iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010613

Ensembl Protein ID

ENSAMXP00000008708.1

UniProt Accession

W5KM96; W5KM96_ASTMX

Genbank Protein ID

ENSAMXP00000008708

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Genbank Nucleotide ID

APWO01056513

Gene Name

wdr4; WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000008345.1	ENSAMXT00000008708.1	ENSAMXP00000008708.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.00e-07	29.8	189	229

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.....sdtllvsGsdDgtikvWDlrtgvllks 38
           gHt+ v+ l f     +   l+sGs+Dgt+k+W + tg+ l+s
   Q: 189  GHTEFVSTL-FvptghP-EWLLSGSGDGTLKLWHYETGRRLQS 229
           688888888.8864322.77*****************998875 PP

Organism

Astyanax mexicanus

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MAAVCCAGDW LLTCSSQYLV AVNIRQSRNR EPFVFDCSKA EQKPTETEAE NKSDGGGSEE 60
KGSDLILACT ISTSGNYAAL TDDNKRLILF RTQPSWQCIS TRWVVRRCTS LMFSQAEDEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGCGG TGTGCTGTGC TGGAGACTGG CTGCTGACAT GCAGCTCTCA GTATTTAGTA 60
GCAGTGAACA TCAGGCAAAG CAGGTCAGCG GCTTTATCTC ATCATAGACC TTTTCTTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0036265--P:RNA (guanine-N7)-methylation
GO:0030488--P:tRNA methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	30.51	3.00e-11	63.20
IUUC-Atr-002431	Amborella trichopoda	33.33	1.00e-12	65.10
IUUC-Apl-003975	Anas platyrhynchos	46.65	3.00e-95	341.00
IUUC-Aca-005170	Anolis carolinensis	43.94	2.00e-81	296.00
IUUC-Aly-005769	Arabidopsis lyrata	31.14	2.00e-26	113.00
IUUC-Ath-006733	Arabidopsis thaliana	31.82	5.00e-27	115.00
IUUC-Acl-008151	Aspergillus clavatus	43.00	1.00e-16	81.30
IUUC-Afl-008518	Aspergillus flavus	30.04	8.00e-18	84.30
IUUC-Afu-009102	Aspergillus fumigatus	28.20	1.00e-18	88.20
IUUC-Ani-009442	Aspergillus nidulans	25.81	3.00e-17	83.20
IUUC-Aor-010133	Aspergillus oryzae	27.58	1.00e-19	90.90
IUUC-Ate-010465	Aspergillus terreus	27.83	1.00e-17	84.30
IUUC-Bgr-012067	Blumeria graminis	49.49	1.00e-19	91.30
IUUC-Bta-012788	Bos taurus	46.03	2.00e-91	329.00
IUUC-Bdi-014458	Brachypodium distachyon	33.19	4.00e-16	79.30
IUUC-Bol-015373	Brassica oleracea	32.16	4.00e-25	110.00
IUUC-Bra-017059	Brassica rapa	32.07	1.00e-24	107.00
IUUC-Cpo-021963	Cavia porcellus	46.21	8.00e-87	313.00
IUUC-Csa-024148	Chlorocebus sabaeus	48.41	9.00e-79	287.00
IUUC-Cne-026834	Cryptococcus neoformans	32.27	5.00e-24	105.00
IUUC-Dre-028427	Danio rerio	68.35	4.00e-165	573.00
IUUC-Dno-028881	Dasypus novemcinctus	40.77	2.00e-74	273.00
IUUC-Dor-030522	Dipodomys ordii	48.91	2.00e-93	335.00
IUUC-Dme-032136	Drosophila melanogaster	35.57	1.00e-22	100.00
IUUC-Fca-035833	Felis catus	47.84	1.00e-88	319.00
IUUC-Fal-037497	Ficedula albicollis	48.84	7.00e-98	350.00
IUUC-Gga-040547	Gallus gallus	47.66	2.00e-95	342.00
IUUC-Gac-041761	Gasterosteus aculeatus	53.14	7.00e-116	410.00
IUUC-Gma-043722	Glycine max	31.67	8.00e-21	94.70
IUUC-Ggo-045340	Gorilla gorilla	46.68	5.00e-84	304.00
IUUC-Hsa-046403	Homo sapiens	45.62	1.00e-81	296.00
IUUC-Hvu-047643	Hordeum vulgare	32.98	1.00e-19	90.90
IUUC-Itr-048103	Ictidomys tridecemlineatus	47.62	6.00e-97	347.00
IUUC-Kpa-049283	Komagataella pastoris	27.97	3.00e-18	85.90
IUUC-Lch-050682	Latimeria chalumnae	45.22	4.00e-99	355.00
IUUC-Lpe-050712	Leersia perrieri	34.21	1.00e-23	104.00
IUUC-Loc-052599	Lepisosteus oculatus	57.79	2.00e-138	485.00
IUUC-Laf-054390	Loxodonta africana	48.41	2.00e-96	346.00
IUUC-Mcc-054747	Macaca mulatta	48.70	1.00e-82	300.00
IUUC-Mtr-058600	Medicago truncatula	34.60	3.00e-22	99.80
IUUC-Mla-059135	Melampsora laricipopulina	28.41	4.00e-14	73.20
IUUC-Mga-059876	Meleagris gallopavo	48.28	7.00e-95	340.00
IUUC-Mvi-060359	Microbotryum violaceum	30.12	1.00e-12	67.80
IUUC-Mmr-061518	Microcebus murinus	45.24	5.00e-84	304.00
IUUC-Mac-065625	Musa acuminata	29.12	1.00e-20	94.70
IUUC-Nfi-068402	Neosartorya fischeri	28.20	8.00e-19	88.20
IUUC-Nle-069914	Nomascus leucogenys	46.97	8.00e-77	280.00
IUUC-Ont-071555	Oreochromis niloticus	54.46	3.00e-116	411.00
IUUC-Oan-072951	Ornithorhynchus anatinus	47.47	2.00e-97	349.00
IUUC-Ocu-074679	Oryctolagus cuniculus	45.09	2.00e-81	295.00
IUUC-Oba-075355	Oryza barthii	26.36	3.00e-11	63.20
IUUC-Obr-076769	Oryza brachyantha	29.02	3.00e-24	105.00
IUUC-Ogl-077168	Oryza glaberrima	31.68	3.00e-24	106.00
IUUC-Ogu-078275	Oryza glumaepatula	25.97	8.00e-11	62.00
IUUC-Oin-079207	Oryza indica	31.68	3.00e-24	106.00
IUUC-Oni-082437	Oryza nivara	26.45	4.00e-10	59.30
IUUC-Opu-084031	Oryza punctata	32.06	1.00e-23	104.00
IUUC-Oru-084380	Oryza rufipogon	26.36	4.00e-11	62.80
IUUC-Osa-085327	Oryza sativa	31.68	4.00e-24	105.00
IUUC-Ola-086716	Oryzias latipes	53.03	3.00e-109	388.00
IUUC-Olu-087708	Ostreococcus lucimarinus	24.54	2.00e-14	73.60
IUUC-Oar-090239	Ovis aries	48.15	5.00e-91	327.00
IUUC-Ptr-090851	Pan troglodytes	46.42	3.00e-83	301.00
IUUC-Pan-092558	Papio anubis	47.92	2.00e-77	282.00
IUUC-Psi-093792	Pelodiscus sinensis	43.80	6.00e-91	327.00
IUUC-Ppa-095757	Physcomitrella patens	33.96	9.00e-26	111.00
IUUC-Pfo-096465	Poecilia formosa	56.23	2.00e-125	442.00
IUUC-Pab-097722	Pongo abelii	48.83	4.00e-88	318.00
IUUC-Pop-098979	Populus trichocarpa	31.49	2.00e-19	90.50
IUUC-Pca-100753	Procavia capensis	46.25	6.00e-62	231.00
IUUC-Ppe-101515	Prunus persica	29.64	8.00e-19	88.20
IUUC-Sja-107780	Schizosaccharomyces japonicus	27.33	2.00e-14	73.60
IUUC-Spo-108251	Schizosaccharomyces pombe	25.08	1.00e-13	70.90
IUUC-Smo-108938	Selaginella moellendorffii	36.74	1.00e-27	117.00
IUUC-Sit-110020	Setaria italica	29.72	1.00e-22	100.00
IUUC-Sly-111543	Solanum lycopersicum	30.55	2.00e-24	106.00
IUUC-Stu-111925	Solanum tuberosum	30.55	6.00e-25	108.00
IUUC-Sbi-114061	Sorghum bicolor	32.83	1.00e-23	103.00
IUUC-Tgu-117321	Taeniopygia guttata	47.55	3.00e-89	322.00
IUUC-Tru-118454	Takifugu rubripes	55.41	1.00e-115	409.00
IUUC-Tni-119894	Tetraodon nigroviridis	51.81	1.00e-104	372.00
IUUC-Tca-121746	Theobroma cacao	31.52	6.00e-21	95.10
IUUC-Tae-124114	Triticum aestivum	32.75	4.00e-19	89.40
IUUC-Tur-126254	Triticum urartu	29.18	2.00e-12	66.60
IUUC-Tbe-127683	Tupaia belangeri	59.26	7.00e-26	111.00
IUUC-Ttr-129056	Tursiops truncatus	44.60	2.00e-83	303.00
IUUC-Vvi-131428	Vitis vinifera	33.88	5.00e-22	98.60
IUUC-Xma-133605	Xiphophorus maculatus	54.29	5.00e-123	434.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence