iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012788

Ensembl Protein ID

ENSBTAP00000028643.4

UniProt Accession

A7E3S5; WDR4_BOVIN

Genbank Protein ID

ABS45012.1

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Genbank Nucleotide ID

BT030696

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000021490.4	ENSBTAT00000028643.4	ENSBTAP00000028643.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.10e-06	26.8	187	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+ + f   +   ll+s+s+D+t+++W++r+g+ l+
   Q: 187  GHTEFVSRI-FvvpNHpELLLSSSGDCTLRLWEYRSGRELH 226
           677777777.789544799******************9876 PP

Organism

Bos taurus

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MASSAGLALC GHALVVRGGS RLLATSTSSS DGDSLFIYDC SAAEKKSQEN KGEDGQPVDQ 60
GSDTVLASTF SKSGSYFVLT DDSKRLILFR TNPWQCLSVR TVVRRCTALT FTASEEKILV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCGGGCAC ATGGCGAGTT CTGCGGGGCT GGCTCTGTGT GGGCATGCGC TGGTGGTTCG 60
GGGCGGTAGC CGGTTGCTGG CTACCTCCAC TTCGAGCAGG TGAGGGGTCG TTCTGGAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0043527--C:tRNA methyltransferase complex
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity
GO:0006400--P:tRNA modification

KEGG

bta:508051

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	27.47	2.00e-13	70.10
IUUC-Apl-003975	Anas platyrhynchos	59.00	1.00e-120	426.00
IUUC-Aca-005170	Anolis carolinensis	54.86	4.00e-107	381.00
IUUC-Aly-005769	Arabidopsis lyrata	30.61	5.00e-25	108.00
IUUC-Ath-006733	Arabidopsis thaliana	30.54	1.00e-23	104.00
IUUC-Acl-008151	Aspergillus clavatus	36.99	4.00e-16	79.30
IUUC-Afl-008518	Aspergillus flavus	31.19	4.00e-17	82.00
IUUC-Afu-009102	Aspergillus fumigatus	35.88	5.00e-14	72.80
IUUC-Ani-009442	Aspergillus nidulans	28.85	2.00e-16	80.90
IUUC-Aor-010133	Aspergillus oryzae	27.12	6.00e-20	92.00
IUUC-Ate-010465	Aspergillus terreus	39.83	1.00e-15	77.80
IUUC-Ame-010613	Astyanax mexicanus	44.79	7.00e-87	314.00
IUUC-Bgr-012067	Blumeria graminis	27.24	3.00e-19	90.10
IUUC-Bdi-014458	Brachypodium distachyon	31.45	3.00e-19	89.70
IUUC-Bol-016398	Brassica oleracea	39.23	2.00e-25	109.00
IUUC-Bra-016644	Brassica rapa	39.56	1.00e-24	109.00
IUUC-Cpo-021963	Cavia porcellus	78.57	4.00e-168	583.00
IUUC-Csa-024148	Chlorocebus sabaeus	77.97	2.00e-162	565.00
IUUC-Cne-026834	Cryptococcus neoformans	35.26	2.00e-20	94.40
IUUC-Dre-028427	Danio rerio	47.03	1.00e-94	340.00
IUUC-Dno-028881	Dasypus novemcinctus	70.60	6.00e-152	530.00
IUUC-Dor-030522	Dipodomys ordii	74.31	2.00e-165	574.00
IUUC-Dme-032136	Drosophila melanogaster	31.55	6.00e-23	101.00
IUUC-Fca-035833	Felis catus	79.10	2.00e-169	587.00
IUUC-Fal-037497	Ficedula albicollis	58.28	3.00e-118	417.00
IUUC-Gga-040547	Gallus gallus	57.99	9.00e-123	433.00
IUUC-Gac-041761	Gasterosteus aculeatus	43.09	5.00e-79	287.00
IUUC-Gma-043722	Glycine max	32.52	1.00e-19	90.90
IUUC-Ggo-045340	Gorilla gorilla	77.97	4.00e-170	590.00
IUUC-Hsa-046403	Homo sapiens	77.24	2.00e-168	585.00
IUUC-Hvu-047643	Hordeum vulgare	31.71	7.00e-22	98.20
IUUC-Itr-048103	Ictidomys tridecemlineatus	77.48	4.00e-173	600.00
IUUC-Kpa-049283	Komagataella pastoris	31.21	5.00e-18	85.50
IUUC-Lch-050682	Latimeria chalumnae	53.33	1.00e-113	402.00
IUUC-Lpe-050712	Leersia perrieri	31.97	1.00e-25	110.00
IUUC-Loc-052599	Lepisosteus oculatus	50.99	7.00e-111	394.00
IUUC-Laf-054390	Loxodonta africana	75.06	1.00e-173	602.00
IUUC-Mcc-054747	Macaca mulatta	77.24	3.00e-166	577.00
IUUC-Mtr-058600	Medicago truncatula	38.42	7.00e-24	104.00
IUUC-Mla-059129	Melampsora laricipopulina	25.64	1.00e-12	67.00
IUUC-Mga-059876	Meleagris gallopavo	57.49	1.00e-123	436.00
IUUC-Mvi-060359	Microbotryum violaceum	31.14	1.00e-12	68.20
IUUC-Mmr-061518	Microcebus murinus	75.30	4.00e-167	580.00
IUUC-Mac-065417	Musa acuminata	27.90	2.00e-21	96.70
IUUC-Nfi-068402	Neosartorya fischeri	30.28	4.00e-14	72.80
IUUC-Nle-069914	Nomascus leucogenys	78.45	8.00e-163	566.00
IUUC-Ont-071555	Oreochromis niloticus	41.99	5.00e-77	281.00
IUUC-Oan-072951	Ornithorhynchus anatinus	69.07	2.00e-151	528.00
IUUC-Ocu-074679	Oryctolagus cuniculus	80.11	2.00e-163	568.00
IUUC-Oba-075355	Oryza barthii	26.30	1.00e-13	70.90
IUUC-Obr-076769	Oryza brachyantha	33.89	2.00e-26	113.00
IUUC-Ogl-077168	Oryza glaberrima	31.41	3.00e-26	112.00
IUUC-Ogu-078275	Oryza glumaepatula	25.28	2.00e-13	70.50
IUUC-Oin-079207	Oryza indica	31.41	3.00e-26	112.00
IUUC-Oni-082437	Oryza nivara	26.81	4.00e-13	69.30
IUUC-Opu-084031	Oryza punctata	31.43	2.00e-24	106.00
IUUC-Oru-084380	Oryza rufipogon	26.30	3.00e-13	69.70
IUUC-Osa-085327	Oryza sativa	31.41	7.00e-26	111.00
IUUC-Ola-086716	Oryzias latipes	42.86	1.00e-74	273.00
IUUC-Olu-087708	Ostreococcus lucimarinus	29.95	2.00e-14	73.20
IUUC-Oar-090239	Ovis aries	97.61	0.00e+00	734.00
IUUC-Ptr-090851	Pan troglodytes	77.97	4.00e-170	590.00
IUUC-Pan-092558	Papio anubis	77.35	8.00e-161	559.00
IUUC-Psi-093792	Pelodiscus sinensis	58.70	1.00e-130	459.00
IUUC-Ppa-095757	Physcomitrella patens	36.46	1.00e-21	97.40
IUUC-Pfo-096465	Poecilia formosa	42.93	2.00e-82	299.00
IUUC-Pab-097722	Pongo abelii	79.42	5.00e-171	593.00
IUUC-Pop-098979	Populus trichocarpa	34.95	7.00e-21	95.10
IUUC-Pca-100753	Procavia capensis	71.63	6.00e-115	407.00
IUUC-Ppe-101515	Prunus persica	30.77	1.00e-20	94.40
IUUC-Sja-107780	Schizosaccharomyces japonicus	29.23	1.00e-14	73.90
IUUC-Spo-108251	Schizosaccharomyces pombe	26.30	1.00e-13	70.90
IUUC-Smo-108938	Selaginella moellendorffii	37.82	5.00e-23	102.00
IUUC-Sit-110020	Setaria italica	30.52	3.00e-23	102.00
IUUC-Sly-111543	Solanum lycopersicum	29.67	8.00e-25	108.00
IUUC-Stu-111925	Solanum tuberosum	28.80	2.00e-24	106.00
IUUC-Sbi-114061	Sorghum bicolor	30.43	8.00e-23	101.00
IUUC-Tgu-117321	Taeniopygia guttata	57.52	1.00e-108	386.00
IUUC-Tru-118454	Takifugu rubripes	44.39	6.00e-78	284.00
IUUC-Tni-119894	Tetraodon nigroviridis	43.86	7.00e-74	270.00
IUUC-Tca-121746	Theobroma cacao	33.68	1.00e-20	94.40
IUUC-Tae-124114	Triticum aestivum	31.45	3.00e-22	99.40
IUUC-Tur-126254	Triticum urartu	26.86	7.00e-15	74.70
IUUC-Tbe-127683	Tupaia belangeri	51.88	4.00e-55	208.00
IUUC-Ttr-129056	Tursiops truncatus	81.64	1.00e-179	622.00
IUUC-Vvi-131428	Vitis vinifera	36.02	5.00e-23	102.00
IUUC-Xma-133605	Xiphophorus maculatus	43.00	2.00e-82	299.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence