iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025395

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog

Genbank Nucleotide ID

EAAA01002629

Gene Name

LOC100179970

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000006781.3	ENSCINT00000013921.3	ENSCINP00000013921.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-47	156.7	192	222
UBD/Beta-Prp	1.50e-90	303.2	55	279

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH++ v+++++  d ++lvsGsdD+tikvW 
   Q: 192  GHSSTVWSVSWsKDgRRLVSGSDDKTIKVWQ 222
           8***********7779**************6 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdls....tgkcv 87
           l++ h+  i++v +sp ++ la++s d+ti +wd ++g++   ++l+ghe+ev+av +s++g++l+t+s+D+ + +w+++    +++c 
   Q: 55   LQDGHQRTIRKVGWSPCGNKLASASFDATICIWDKSSGQFesAATLEGHENEVKAVAWSQSGEYLATCSRDKSVWIWSVDdeedDFECA 143
           6888999*********************************9999*********************************8887788***** PP
   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl......... 166
            +l+ h+++v +++++p    ++s+s d+ti++++ + g++l+  tlsgh+++v++v++++dg+ lvsGs+D+t+++W+          
   Q: 144  GVLTVHTQDVKDIAWHPFEPIVASASYDDTIKLFKEDDGEWLSFaTLSGHSSTVWSVSWSKDGRRLVSGSDDKTIKVWQKyepgnmegi 232
           *****************99***********************878******************************************** PP
   S: 167  ......ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklw 207
                 +t k++ tl+g+ ++++y++++ ++   ++++s d++++++
   Q: 233  atkgetPTWKCVCTLSGYFNQPIYCVTWCHQTDMIAACSGDNSIIVF 279
           ********************************************998 PP

Organism

Ciona intestinalis

Functional Description
(View)

Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

MTPTLDCVAS LNDHGDRVWD VKWNPKGTLL ATCGTDKTIR IWGKEGDKWV CKSILQDGHQ 60
RTIRKVGWSP CGNKLASASF DATICIWDKS SGQFESAATL EGHENEVKAV AWSQSGEYLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTTTGCCA TGACTCCGAC GTTAGATTGT GTTGCATCGT TAAACGATCA CGGGGACAGA 60
GTATGGGACG TGAAGTGGAA TCCTAAAGGA ACACTGTTGG CGACTTGTGG CACAGATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR028608--CIAO1/Cia1
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0016226--P:iron-sulfur cluster assembly

KEGG

cin:100179970

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	41.98	3.00e-56	211.00
IUUC-Aml-001317	Ailuropoda melanoleuca	57.06	4.00e-100	356.00
IUUC-Atr-003029	Amborella trichopoda	44.76	2.00e-72	265.00
IUUC-Apl-004042	Anas platyrhynchos	51.56	3.00e-32	129.00
IUUC-Aly-006458	Arabidopsis lyrata	43.57	4.00e-71	260.00
IUUC-Ath-006671	Arabidopsis thaliana	44.15	2.00e-71	261.00
IUUC-Ago-007820	Ashbya gossypii	38.24	2.00e-53	201.00
IUUC-Acl-008042	Aspergillus clavatus	30.25	2.00e-43	168.00
IUUC-Afl-008639	Aspergillus flavus	29.83	3.00e-41	160.00
IUUC-Afu-008899	Aspergillus fumigatus	28.41	3.00e-41	161.00
IUUC-Ani-009453	Aspergillus nidulans	29.59	6.00e-42	163.00
IUUC-Ang-009758	Aspergillus niger	32.27	7.00e-43	166.00
IUUC-Aor-010212	Aspergillus oryzae	29.83	3.00e-41	160.00
IUUC-Ate-010314	Aspergillus terreus	28.64	1.00e-42	166.00
IUUC-Ame-010676	Astyanax mexicanus	55.52	6.00e-103	365.00
IUUC-Bgr-012095	Blumeria graminis	29.64	1.00e-33	136.00
IUUC-Bta-012884	Bos taurus	56.42	4.00e-100	356.00
IUUC-Bci-013622	Botrytis cinerea	28.81	3.00e-32	131.00
IUUC-Bdi-014614	Brachypodium distachyon	45.72	2.00e-75	274.00
IUUC-Bol-016439	Brassica oleracea	42.73	6.00e-69	253.00
IUUC-Bra-016830	Brassica rapa	41.67	3.00e-67	246.00
IUUC-Cel-018709	Caenorhabditis elegans	39.34	4.00e-58	216.00
IUUC-Cja-019822	Callithrix jacchus	56.42	1.00e-100	358.00
IUUC-Cfa-020823	Canis familiaris	56.42	4.00e-100	356.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	44.86	8.00e-70	255.00
IUUC-Csa-023754	Chlorocebus sabaeus	56.72	4.00e-102	362.00
IUUC-Csv-025943	Ciona savignyi	82.14	2.00e-166	576.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	31.65	1.00e-28	119.00
IUUC-Cne-026939	Cryptococcus neoformans	29.80	2.00e-39	155.00
IUUC-Cme-027239	Cyanidioschyzon merolae	41.98	2.00e-41	162.00
IUUC-Dre-028172	Danio rerio	54.35	3.00e-99	353.00
IUUC-Dno-029472	Dasypus novemcinctus	58.82	3.00e-88	317.00
IUUC-Dor-031134	Dipodomys ordii	49.25	3.00e-78	283.00
IUUC-Dse-031535	Dothistroma septosporum	27.83	2.00e-36	144.00
IUUC-Dme-032020	Drosophila melanogaster	57.06	7.00e-104	369.00
IUUC-Eca-033700	Equus caballus	57.01	3.00e-102	363.00
IUUC-Eeu-035010	Erinaceus europaeus	56.42	2.00e-98	350.00
IUUC-Fca-036309	Felis catus	52.08	2.00e-94	337.00
IUUC-Fal-037243	Ficedula albicollis	61.40	2.00e-65	240.00
IUUC-Fox-038058	Fusarium oxysporum	29.63	1.00e-34	140.00
IUUC-Fso-038459	Fusarium solani	29.53	1.00e-32	132.00
IUUC-Gmo-039375	Gadus morhua	52.37	3.00e-88	316.00
IUUC-Ggr-040002	Gaeumannomyces graminis	31.09	9.00e-31	126.00
IUUC-Gga-040294	Gallus gallus	55.93	5.00e-80	289.00
IUUC-Gac-042499	Gasterosteus aculeatus	55.52	2.00e-95	340.00
IUUC-Gma-043543	Glycine max	42.57	6.00e-71	259.00
IUUC-Ggo-045181	Gorilla gorilla	56.72	4.00e-102	362.00
IUUC-Hsa-046528	Homo sapiens	56.72	4.00e-102	362.00
IUUC-Hvu-047341	Hordeum vulgare	51.60	8.00e-50	188.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	57.61	2.00e-103	367.00
IUUC-Kpa-049353	Komagataella pastoris	35.96	5.00e-54	203.00
IUUC-Lch-049763	Latimeria chalumnae	56.12	1.00e-103	368.00
IUUC-Lpe-051500	Leersia perrieri	41.51	8.00e-72	262.00
IUUC-Loc-052021	Lepisosteus oculatus	57.01	4.00e-101	359.00
IUUC-Lma-053331	Leptosphaeria maculans	28.54	6.00e-41	161.00
IUUC-Laf-054558	Loxodonta africana	56.42	2.00e-99	354.00
IUUC-Mcc-055374	Macaca mulatta	56.42	3.00e-101	359.00
IUUC-Meu-056042	Macropus eugenii	60.00	2.00e-65	240.00
IUUC-Mor-057187	Magnaporthe oryzae	28.74	7.00e-32	130.00
IUUC-Mtr-058072	Medicago truncatula	43.73	3.00e-71	260.00
IUUC-Mla-059108	Melampsora laricipopulina	30.37	8.00e-42	163.00
IUUC-Mga-059370	Meleagris gallopavo	44.69	5.00e-60	223.00
IUUC-Mvi-060495	Microbotryum violaceum	34.82	6.00e-47	180.00
IUUC-Mmr-060902	Microcebus murinus	56.72	4.00e-101	359.00
IUUC-Mdo-062510	Monodelphis domestica	58.51	5.00e-101	359.00
IUUC-Mmu-063575	Mus musculus	57.06	1.00e-100	358.00
IUUC-Mac-065322	Musa acuminata	45.03	2.00e-76	277.00
IUUC-Mpu-065925	Mustela putorius furo	56.42	5.00e-101	359.00
IUUC-Mlu-067755	Myotis lucifugus	56.12	4.00e-100	356.00
IUUC-Nfi-068327	Neosartorya fischeri	29.05	5.00e-41	160.00
IUUC-Ncr-068845	Neurospora crassa	27.15	1.00e-25	109.00
IUUC-Nle-069406	Nomascus leucogenys	55.82	2.00e-98	350.00
IUUC-Opr-070416	Ochotona princeps	45.97	5.00e-74	269.00
IUUC-Ont-071936	Oreochromis niloticus	56.42	2.00e-97	347.00
IUUC-Oan-073452	Ornithorhynchus anatinus	57.23	3.00e-42	162.00
IUUC-Ocu-074791	Oryctolagus cuniculus	56.72	3.00e-101	360.00
IUUC-Oba-075636	Oryza barthii	45.54	4.00e-77	280.00
IUUC-Obr-076742	Oryza brachyantha	44.95	5.00e-65	239.00
IUUC-Ogl-077766	Oryza glaberrima	45.54	4.00e-77	280.00
IUUC-Ogu-079039	Oryza glumaepatula	45.54	2.00e-77	281.00
IUUC-Oin-079315	Oryza indica	45.55	2.00e-66	244.00
IUUC-Olo-080669	Oryza longistaminata	40.73	2.00e-69	254.00
IUUC-Ome-081490	Oryza meridionalis	45.83	2.00e-77	281.00
IUUC-Oni-082572	Oryza nivara	45.54	4.00e-77	280.00
IUUC-Opu-083732	Oryza punctata	45.83	3.00e-78	283.00
IUUC-Oru-084763	Oryza rufipogon	45.54	4.00e-77	280.00
IUUC-Osa-085372	Oryza sativa	45.54	4.00e-77	280.00
IUUC-Ola-087379	Oryzias latipes	54.63	3.00e-93	333.00
IUUC-Olu-087801	Ostreococcus lucimarinus	30.99	7.00e-35	139.00
IUUC-Oga-089076	Otolemur garnettii	56.72	6.00e-102	362.00
IUUC-Oar-090022	Ovis aries	56.72	7.00e-101	358.00
IUUC-Ptr-090809	Pan troglodytes	56.72	4.00e-102	362.00
IUUC-Pan-091685	Papio anubis	56.72	2.00e-102	365.00
IUUC-Psi-093046	Pelodiscus sinensis	56.72	2.00e-100	357.00
IUUC-Pma-094181	Petromyzon marinus	56.12	5.00e-106	375.00
IUUC-Pno-094882	Phaeosphaeria nodorum	28.87	6.00e-40	157.00
IUUC-Ppa-095172	Physcomitrella patens	43.19	9.00e-70	255.00
IUUC-Pfo-096396	Poecilia formosa	54.33	2.00e-95	341.00
IUUC-Pab-098427	Pongo abelii	56.12	9.00e-100	355.00
IUUC-Pop-100016	Populus trichocarpa	43.95	3.00e-74	270.00
IUUC-Pca-101048	Procavia capensis	57.01	8.00e-101	358.00
IUUC-Ppe-102050	Prunus persica	40.85	2.00e-67	248.00
IUUC-Pva-103117	Pteropus vampyrus	56.12	2.00e-100	357.00
IUUC-Pgr-103307	Puccinia graminis	31.95	4.00e-45	174.00
IUUC-Ptt-103938	Puccinia triticina	34.82	4.00e-39	153.00
IUUC-Pte-104315	Pyrenophora teres	29.15	3.00e-42	164.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	28.91	1.00e-42	166.00
IUUC-Rno-105523	Rattus norvegicus	58.49	1.00e-99	355.00
IUUC-Sce-106297	Saccharomyces cerevisiae	35.96	4.00e-51	193.00
IUUC-Sha-106981	Sarcophilus harrisii	59.52	7.00e-87	311.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	36.07	9.00e-52	196.00
IUUC-Spo-108214	Schizosaccharomyces pombe	37.85	8.00e-47	180.00
IUUC-Smo-109034	Selaginella moellendorffii	43.58	1.00e-68	251.00
IUUC-Sit-110663	Setaria italica	46.11	5.00e-77	279.00
IUUC-Sly-110898	Solanum lycopersicum	42.06	2.00e-63	234.00
IUUC-Stu-112647	Solanum tuberosum	44.74	2.00e-52	197.00
IUUC-Sbi-114288	Sorghum bicolor	45.83	8.00e-76	275.00
IUUC-Sre-115065	Sporisorium reilianum	37.33	2.00e-56	211.00
IUUC-Ssc-115960	Sus scrofa	53.41	9.00e-103	365.00
IUUC-Tru-118382	Takifugu rubripes	57.31	3.00e-105	373.00
IUUC-Tsy-119585	Tarsius syrichta	50.75	5.00e-82	296.00
IUUC-Tni-120133	Tetraodon nigroviridis	55.59	6.00e-97	345.00
IUUC-Tca-121167	Theobroma cacao	44.41	1.00e-66	245.00
IUUC-Tre-122119	Trichoderma reesei	27.78	1.00e-31	129.00
IUUC-Tvi-122407	Trichoderma virens	27.87	2.00e-34	138.00
IUUC-Tae-125748	Triticum aestivum	44.94	6.00e-71	259.00
IUUC-Tur-126682	Triticum urartu	45.19	1.00e-55	208.00
IUUC-Tme-127095	Tuber melanosporum	36.62	2.00e-50	191.00
IUUC-Tbe-128004	Tupaia belangeri	57.06	3.00e-101	360.00
IUUC-Ttr-129284	Tursiops truncatus	55.75	8.00e-100	355.00
IUUC-Uma-129527	Ustilago maydis	36.90	6.00e-55	206.00
IUUC-Vda-129854	Verticillium dahliae	28.27	1.00e-29	122.00
IUUC-Vpa-130681	Vicugna pacos	67.54	5.00e-34	136.00
IUUC-Vvi-131004	Vitis vinifera	43.62	1.00e-70	258.00
IUUC-Xtr-131928	Xenopus tropicalis	53.73	9.00e-93	332.00
IUUC-Xma-134290	Xiphophorus maculatus	52.84	2.00e-91	327.00
IUUC-Yli-134364	Yarrowia lipolytica	39.07	2.00e-55	207.00
IUUC-Zma-135658	Zea mays	44.35	1.00e-71	261.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence