iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049763

Ensembl Protein ID

ENSLACP00000003289.1

UniProt Accession

H3A0W8; H3A0W8_LATCH

Genbank Protein ID

ENSLACP00000003289

Protein Name

Probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat-containing protein 39

Genbank Nucleotide ID

AFYH01216332

Gene Name

CIAO1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000002942.1	ENSLACT00000003319.1	ENSLACP00000003289.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.40e-44	146.0	194	226
UBD/Beta-Prp	9.10e-54	182.9	10	180

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvW.Dl 30
           gH++ v+++af  s+ +l+s+sdD+t+k+W D+
   Q: 194  GHESTVWSIAFdkSGERLASCSDDKTVKIWqDY 226
           8**********97779**************775 PP

UBD/Beta-Prp

   S: 2    iktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrsl.sgheaevtavkfspdgkilvtgseDrtikvw..dlstgk 85
           i+ +++h++s++  +++sp ++lla+ + d+ i++w  +  +    + l +gh+ +v+ v +sp g++l+++s D+t ++w    + ++
   Q: 10   ITRFSAHPDSRCWFLAWSPTGTLLASCGGDRVIRIWGQEGDSWvcKSVLeEGHQRTVRKVAWSPCGNYLASASFDATTCIWrkKQEEFE 98
           56788999999999**********************988765543666789******************************98888*** PP
   S: 86   cvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWd 165
           c+ tl+ghe++v s+s+ psg+ l++ s+d+ + vw+++++ ++e   +l+ h++ v +v +hp+g ll+s+s+D+t++l++
   Q: 99   CITTLEGHENEVKSVSWAPSGSLLATCSRDKSVWVWEVDEDDEYECvsVLNSHTQDVKHVIWHPNGELLASASYDNTIKLYK 180
           **************************************9987776566*******************************995 PP

Organism

Latimeria chalumnae

Functional Description
(View)

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

IIMKDSLALI TRFSAHPDSR CWFLAWSPTG TLLASCGGDR VIRIWGQEGD SWVCKSVLEE 60
GHQRTVRKVA WSPCGNYLAS ASFDATTCIW RKKQEEFECI TTLEGHENEV KSVSWAPSGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTGTTGAG GGAGTTTGAG ACTTCCTCAG ATAGCGGGAG CCAGTTTGGG TTGGTATCAG 60
AAATGTACTC TGTAAGTTGT CAGATCTGTT GCAGTGAGAG TTTCCAACAT CGGGACTGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0016226--P:iron-sulfur cluster assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	50.55	8.00e-70	258.00
IUUC-Aml-001317	Ailuropoda melanoleuca	79.94	1.00e-155	541.00
IUUC-Atr-003029	Amborella trichopoda	50.14	2.00e-92	332.00
IUUC-Apl-004042	Anas platyrhynchos	67.42	8.00e-51	191.00
IUUC-Aly-006458	Arabidopsis lyrata	50.14	1.00e-87	316.00
IUUC-Ath-006671	Arabidopsis thaliana	49.44	1.00e-87	315.00
IUUC-Ago-007820	Ashbya gossypii	38.89	5.00e-56	211.00
IUUC-Acl-008042	Aspergillus clavatus	32.02	2.00e-47	182.00
IUUC-Afl-008639	Aspergillus flavus	31.98	6.00e-52	197.00
IUUC-Afu-008899	Aspergillus fumigatus	31.05	3.00e-46	179.00
IUUC-Ani-009453	Aspergillus nidulans	30.93	7.00e-47	181.00
IUUC-Ang-009758	Aspergillus niger	32.67	7.00e-51	194.00
IUUC-Aor-010212	Aspergillus oryzae	31.98	6.00e-52	197.00
IUUC-Ate-010314	Aspergillus terreus	32.13	1.00e-50	193.00
IUUC-Ame-010676	Astyanax mexicanus	72.02	4.00e-152	530.00
IUUC-Bgr-012095	Blumeria graminis	30.45	2.00e-36	146.00
IUUC-Bta-012884	Bos taurus	79.94	1.00e-156	545.00
IUUC-Bci-013622	Botrytis cinerea	31.02	2.00e-36	146.00
IUUC-Bdi-014614	Brachypodium distachyon	50.45	2.00e-86	312.00
IUUC-Bol-016439	Brassica oleracea	49.14	9.00e-85	306.00
IUUC-Bra-016830	Brassica rapa	47.84	2.00e-83	301.00
IUUC-Cel-018709	Caenorhabditis elegans	39.76	3.00e-63	235.00
IUUC-Cja-019822	Callithrix jacchus	80.24	1.00e-154	539.00
IUUC-Cfa-020823	Canis familiaris	80.24	1.00e-156	545.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	47.14	8.00e-79	286.00
IUUC-Csa-023754	Chlorocebus sabaeus	80.24	9.00e-156	542.00
IUUC-Cin-025395	Ciona intestinalis	56.72	5.00e-114	404.00
IUUC-Csv-025943	Ciona savignyi	54.33	1.00e-110	392.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	30.59	6.00e-38	151.00
IUUC-Cne-026939	Cryptococcus neoformans	32.13	5.00e-47	181.00
IUUC-Cme-027239	Cyanidioschyzon merolae	41.56	4.00e-46	178.00
IUUC-Dre-028172	Danio rerio	72.54	3.00e-149	520.00
IUUC-Dno-029472	Dasypus novemcinctus	80.90	1.00e-132	465.00
IUUC-Dor-031134	Dipodomys ordii	69.76	1.00e-127	449.00
IUUC-Dse-031535	Dothistroma septosporum	28.57	9.00e-43	167.00
IUUC-Dme-032020	Drosophila melanogaster	60.88	2.00e-115	408.00
IUUC-Eca-033700	Equus caballus	80.54	1.00e-157	548.00
IUUC-Eeu-035010	Erinaceus europaeus	78.44	1.00e-151	528.00
IUUC-Fca-036309	Felis catus	71.94	3.00e-146	510.00
IUUC-Fal-037243	Ficedula albicollis	66.51	3.00e-81	293.00
IUUC-Fox-038058	Fusarium oxysporum	32.18	5.00e-43	169.00
IUUC-Fso-038459	Fusarium solani	31.69	8.00e-40	157.00
IUUC-Gmo-039375	Gadus morhua	73.35	2.00e-136	478.00
IUUC-Ggr-040002	Gaeumannomyces graminis	33.05	4.00e-38	152.00
IUUC-Gga-040294	Gallus gallus	75.09	7.00e-119	420.00
IUUC-Gac-042499	Gasterosteus aculeatus	72.32	2.00e-135	474.00
IUUC-Gma-043543	Glycine max	47.80	2.00e-86	311.00
IUUC-Ggo-045181	Gorilla gorilla	80.24	9.00e-156	542.00
IUUC-Hsa-046528	Homo sapiens	80.24	9.00e-156	542.00
IUUC-Hvu-047341	Hordeum vulgare	58.51	4.00e-57	213.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	79.94	2.00e-155	541.00
IUUC-Kpa-049353	Komagataella pastoris	35.98	5.00e-56	211.00
IUUC-Lpe-051500	Leersia perrieri	43.77	1.00e-81	296.00
IUUC-Loc-052021	Lepisosteus oculatus	80.06	9.00e-157	545.00
IUUC-Lma-053331	Leptosphaeria maculans	33.92	2.00e-52	200.00
IUUC-Laf-054558	Loxodonta africana	80.24	1.00e-155	542.00
IUUC-Mcc-055374	Macaca mulatta	79.94	6.00e-155	539.00
IUUC-Meu-056042	Macropus eugenii	69.04	1.00e-99	355.00
IUUC-Mor-057187	Magnaporthe oryzae	32.26	6.00e-39	154.00
IUUC-Mtr-058072	Medicago truncatula	47.95	6.00e-86	310.00
IUUC-Mla-059108	Melampsora laricipopulina	31.60	7.00e-51	194.00
IUUC-Mga-059370	Meleagris gallopavo	58.98	5.00e-95	340.00
IUUC-Mvi-060495	Microbotryum violaceum	37.11	1.00e-54	207.00
IUUC-Mmr-060902	Microcebus murinus	80.24	1.00e-156	545.00
IUUC-Mdo-062510	Monodelphis domestica	80.84	1.00e-150	525.00
IUUC-Mmu-063575	Mus musculus	80.54	1.00e-155	542.00
IUUC-Mac-065322	Musa acuminata	50.59	3.00e-90	324.00
IUUC-Mpu-065925	Mustela putorius furo	79.64	1.00e-156	545.00
IUUC-Mlu-067755	Myotis lucifugus	80.84	2.00e-158	551.00
IUUC-Nfi-068327	Neosartorya fischeri	30.54	2.00e-45	176.00
IUUC-Ncr-068845	Neurospora crassa	29.62	5.00e-31	128.00
IUUC-Nle-069406	Nomascus leucogenys	79.34	1.00e-151	528.00
IUUC-Opr-070416	Ochotona princeps	65.57	3.00e-116	411.00
IUUC-Ont-071936	Oreochromis niloticus	72.70	6.00e-139	486.00
IUUC-Oan-073452	Ornithorhynchus anatinus	75.76	3.00e-64	236.00
IUUC-Ocu-074791	Oryctolagus cuniculus	80.54	8.00e-156	542.00
IUUC-Oba-075636	Oryza barthii	49.26	2.00e-89	322.00
IUUC-Obr-076742	Oryza brachyantha	49.65	2.00e-78	285.00
IUUC-Ogl-077766	Oryza glaberrima	49.26	2.00e-89	322.00
IUUC-Ogu-079039	Oryza glumaepatula	48.02	1.00e-89	323.00
IUUC-Oin-079315	Oryza indica	49.66	6.00e-79	287.00
IUUC-Olo-080669	Oryza longistaminata	43.78	2.00e-81	295.00
IUUC-Ome-081490	Oryza meridionalis	49.26	2.00e-89	322.00
IUUC-Oni-082572	Oryza nivara	49.26	2.00e-89	322.00
IUUC-Opu-083732	Oryza punctata	50.00	2.00e-90	325.00
IUUC-Oru-084763	Oryza rufipogon	49.26	2.00e-89	322.00
IUUC-Osa-085372	Oryza sativa	49.26	2.00e-89	322.00
IUUC-Ola-087379	Oryzias latipes	72.40	9.00e-136	476.00
IUUC-Olu-087801	Ostreococcus lucimarinus	34.52	5.00e-41	161.00
IUUC-Oga-089076	Otolemur garnettii	80.24	5.00e-157	546.00
IUUC-Oar-090022	Ovis aries	79.94	8.00e-157	546.00
IUUC-Ptr-090809	Pan troglodytes	80.24	9.00e-156	542.00
IUUC-Pan-091685	Papio anubis	80.24	1.00e-157	550.00
IUUC-Psi-093046	Pelodiscus sinensis	80.54	4.00e-156	543.00
IUUC-Pma-094181	Petromyzon marinus	63.31	2.00e-130	458.00
IUUC-Pno-094882	Phaeosphaeria nodorum	33.57	2.00e-53	203.00
IUUC-Ppa-095172	Physcomitrella patens	48.10	2.00e-86	312.00
IUUC-Pfo-096396	Poecilia formosa	70.92	2.00e-136	478.00
IUUC-Pab-098427	Pongo abelii	80.24	4.00e-154	536.00
IUUC-Pop-100016	Populus trichocarpa	51.32	1.00e-89	322.00
IUUC-Pca-101048	Procavia capensis	79.94	6.00e-156	543.00
IUUC-Ppe-102050	Prunus persica	46.29	6.00e-85	307.00
IUUC-Pva-103117	Pteropus vampyrus	80.54	3.00e-157	547.00
IUUC-Pgr-103307	Puccinia graminis	34.56	3.00e-55	209.00
IUUC-Ptt-103938	Puccinia triticina	39.44	1.00e-48	186.00
IUUC-Pte-104315	Pyrenophora teres	33.57	2.00e-54	206.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	33.09	8.00e-54	204.00
IUUC-Rno-105523	Rattus norvegicus	81.44	4.00e-157	546.00
IUUC-Sce-106297	Saccharomyces cerevisiae	39.59	6.00e-60	224.00
IUUC-Sha-106981	Sarcophilus harrisii	81.25	6.00e-127	446.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	37.90	7.00e-53	201.00
IUUC-Spo-108214	Schizosaccharomyces pombe	40.56	2.00e-55	210.00
IUUC-Smo-109034	Selaginella moellendorffii	43.84	5.00e-79	287.00
IUUC-Sit-110663	Setaria italica	50.60	2.00e-90	325.00
IUUC-Sly-110898	Solanum lycopersicum	48.24	1.00e-81	296.00
IUUC-Stu-112647	Solanum tuberosum	52.42	2.00e-71	261.00
IUUC-Sbi-114288	Sorghum bicolor	48.67	2.00e-87	315.00
IUUC-Sre-115065	Sporisorium reilianum	41.56	2.00e-71	263.00
IUUC-Ssc-115960	Sus scrofa	73.29	4.00e-156	543.00
IUUC-Tru-118382	Takifugu rubripes	70.33	4.00e-145	507.00
IUUC-Tsy-119585	Tarsius syrichta	71.86	3.00e-134	471.00
IUUC-Tni-120133	Tetraodon nigroviridis	72.42	3.00e-139	487.00
IUUC-Tca-121167	Theobroma cacao	47.51	1.00e-79	289.00
IUUC-Tre-122119	Trichoderma reesei	29.65	9.00e-38	150.00
IUUC-Tvi-122407	Trichoderma virens	29.03	8.00e-40	157.00
IUUC-Tae-125748	Triticum aestivum	49.56	7.00e-85	306.00
IUUC-Tur-126682	Triticum urartu	51.13	3.00e-70	258.00
IUUC-Tme-127095	Tuber melanosporum	36.59	2.00e-60	225.00
IUUC-Tbe-128004	Tupaia belangeri	80.54	3.00e-157	547.00
IUUC-Ttr-129284	Tursiops truncatus	78.34	1.00e-151	529.00
IUUC-Uma-129527	Ustilago maydis	42.36	4.00e-73	268.00
IUUC-Vda-129854	Verticillium dahliae	31.65	5.00e-39	155.00
IUUC-Vpa-130681	Vicugna pacos	88.79	2.00e-46	179.00
IUUC-Vvi-131004	Vitis vinifera	51.34	9.00e-85	306.00
IUUC-Xtr-131928	Xenopus tropicalis	78.14	5.00e-148	516.00
IUUC-Xma-134290	Xiphophorus maculatus	69.73	8.00e-133	466.00
IUUC-Yli-134364	Yarrowia lipolytica	43.15	2.00e-64	238.00
IUUC-Zma-135658	Zea mays	49.56	2.00e-88	318.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence