iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035590

Ensembl Protein ID

ENSFCAP00000024481.1

UniProt Accession

M3XCX5; M3XCX5_FELCA

Genbank Protein ID

ENSFCAP00000024481

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02046859

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000022061.1	ENSFCAT00000025594.1	ENSFCAP00000024481.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.20e-103	346.2	392	730

Active Site

Position(s)	Description	Evidence
698	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G+l+g+a++++  ld+
   Q: 392  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKC-----DNYSEFRLVGILMGLAVYNSITLDI 475
           589***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++ +dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k+++LkpgG++ipV
   Q: 476  RFPPCCYKKLLSPpiipsdqntpvgicSVTTDDLCQIMPELAHGLSELLSY-EGNVEED-FYSTFQVFQEEFGIIKSYNLKPGGDKIPV 562
           *************666666666665555**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l+v++ l+++i +q++af+ Gf++v+  + l l+++ee+e+l+cG++e+d+++l++ t+y+g y +++ +i++Fw+v+ 
   Q: 563  TNQNRKEYVQLYVDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPELDMHALQRSTQYDG-YAKTDLTIRYFWDVVL 650
           **********************************************************************76.**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y+sk+ lk+kL++ i++++gF+l+
   Q: 651  GFPLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKnETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE 730
           *****************************...9999967777**************************************985 PP

Organism

Felis catus

Protein Sequence
(Fasta)

GLDRGSKGQI STFSSFVSTV NQKKEAAENR SSPTHLVFPN IKNVRDLPPI CLDVRQKQRI 60
STEASSSEMK APVLPEPVLP NQPKTMKDFQ EDTEKAKSSG DWKAVHDFYL TTFDSFPELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTTGGACA GAGGATCCAA AGGCCAAATT TCCACTTTTA GCAGTTTTGT TTCAACTGTT 60
AACCAGAAGA AAGAAGCTGC TGAAAACAGA AGTTCACCTA CACATCTTGT TTTCCCTAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	97.82	0.00e+00	1474.00
IUUC-Apl-003589	Anas platyrhynchos	86.59	0.00e+00	1291.00
IUUC-Aca-004350	Anolis carolinensis	81.37	0.00e+00	1204.00
IUUC-Ago-007908	Ashbya gossypii	34.86	5.00e-80	292.00
IUUC-Acl-008288	Aspergillus clavatus	36.02	9.00e-98	352.00
IUUC-Afl-008402	Aspergillus flavus	34.49	3.00e-90	326.00
IUUC-Afu-008762	Aspergillus fumigatus	34.81	5.00e-94	339.00
IUUC-Ani-009176	Aspergillus nidulans	35.71	5.00e-92	332.00
IUUC-Ang-009791	Aspergillus niger	36.20	1.00e-92	334.00
IUUC-Aor-009921	Aspergillus oryzae	34.33	2.00e-89	323.00
IUUC-Ate-010295	Aspergillus terreus	35.97	5.00e-100	359.00
IUUC-Ame-010660	Astyanax mexicanus	82.94	4.00e-154	536.00
IUUC-Bgr-011981	Blumeria graminis	32.57	6.00e-93	335.00
IUUC-Bta-012945	Bos taurus	96.16	0.00e+00	1424.00
IUUC-Bci-013697	Botrytis cinerea	33.39	3.00e-79	290.00
IUUC-Cja-019263	Callithrix jacchus	94.69	0.00e+00	1404.00
IUUC-Cfa-020486	Canis familiaris	98.45	0.00e+00	1333.00
IUUC-Cpo-021755	Cavia porcellus	94.66	0.00e+00	1413.00
IUUC-Csa-023814	Chlorocebus sabaeus	95.80	0.00e+00	1343.00
IUUC-Cho-024980	Choloepus hoffmanni	78.49	0.00e+00	1119.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	41.77	8.00e-97	348.00
IUUC-Dre-028551	Danio rerio	77.02	0.00e+00	1146.00
IUUC-Dno-029497	Dasypus novemcinctus	93.77	0.00e+00	1276.00
IUUC-Dor-030867	Dipodomys ordii	83.13	0.00e+00	1209.00
IUUC-Dse-031239	Dothistroma septosporum	29.51	2.00e-88	320.00
IUUC-Ete-032902	Echinops telfairi	79.59	0.00e+00	1164.00
IUUC-Eca-033678	Equus caballus	96.58	0.00e+00	1429.00
IUUC-Eeu-035262	Erinaceus europaeus	79.30	0.00e+00	1061.00
IUUC-Fal-037123	Ficedula albicollis	82.86	0.00e+00	1222.00
IUUC-Fox-037941	Fusarium oxysporum	40.48	2.00e-99	357.00
IUUC-Fso-038388	Fusarium solani	41.27	3.00e-102	366.00
IUUC-Gmo-039553	Gadus morhua	66.93	0.00e+00	851.00
IUUC-Ggr-040110	Gaeumannomyces graminis	40.87	2.00e-97	350.00
IUUC-Gga-040406	Gallus gallus	86.99	0.00e+00	1328.00
IUUC-Gac-042141	Gasterosteus aculeatus	76.23	0.00e+00	1109.00
IUUC-Ggo-045504	Gorilla gorilla	94.41	0.00e+00	1406.00
IUUC-Hsa-045786	Homo sapiens	95.21	0.00e+00	1413.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	90.12	0.00e+00	1236.00
IUUC-Kpa-049152	Komagataella pastoris	34.36	1.00e-75	277.00
IUUC-Lch-049824	Latimeria chalumnae	81.91	0.00e+00	1110.00
IUUC-Loc-052173	Lepisosteus oculatus	80.16	0.00e+00	1189.00
IUUC-Laf-054017	Loxodonta africana	95.78	0.00e+00	1345.00
IUUC-Mcc-055713	Macaca mulatta	95.37	0.00e+00	1395.00
IUUC-Meu-056212	Macropus eugenii	70.37	8.00e-118	417.00
IUUC-Mor-057045	Magnaporthe oryzae	36.59	4.00e-89	323.00
IUUC-Mla-059187	Melampsora laricipopulina	44.37	2.00e-87	316.00
IUUC-Mga-059884	Meleagris gallopavo	80.46	0.00e+00	1171.00
IUUC-Mmr-061344	Microcebus murinus	94.65	0.00e+00	1408.00
IUUC-Mdo-062653	Monodelphis domestica	89.25	0.00e+00	1320.00
IUUC-Mmu-063775	Mus musculus	92.48	0.00e+00	1304.00
IUUC-Mpu-066069	Mustela putorius furo	98.49	0.00e+00	1366.00
IUUC-Mlu-067925	Myotis lucifugus	96.58	0.00e+00	1412.00
IUUC-Nfi-068439	Neosartorya fischeri	34.98	2.00e-94	340.00
IUUC-Ncr-068903	Neurospora crassa	37.68	2.00e-91	330.00
IUUC-Nle-070046	Nomascus leucogenys	95.23	0.00e+00	1417.00
IUUC-Opr-071085	Ochotona princeps	80.20	5.00e-138	484.00
IUUC-Ont-072126	Oreochromis niloticus	73.98	0.00e+00	1152.00
IUUC-Oan-072933	Ornithorhynchus anatinus	89.49	0.00e+00	1181.00
IUUC-Ocu-073800	Oryctolagus cuniculus	96.83	0.00e+00	1301.00
IUUC-Ola-086988	Oryzias latipes	76.71	0.00e+00	1116.00
IUUC-Oga-088117	Otolemur garnettii	96.72	0.00e+00	1135.00
IUUC-Oar-089371	Ovis aries	95.89	0.00e+00	1401.00
IUUC-Ptr-090551	Pan troglodytes	94.21	0.00e+00	1371.00
IUUC-Pan-092067	Papio anubis	95.89	0.00e+00	1402.00
IUUC-Psi-092963	Pelodiscus sinensis	87.53	0.00e+00	1268.00
IUUC-Pfo-096562	Poecilia formosa	71.93	0.00e+00	1116.00
IUUC-Pab-098680	Pongo abelii	95.48	0.00e+00	1414.00
IUUC-Pca-100986	Procavia capensis	77.50	0.00e+00	907.00
IUUC-Pva-102219	Pteropus vampyrus	81.16	0.00e+00	1078.00
IUUC-Pgr-103315	Puccinia graminis	35.76	7.00e-96	345.00
IUUC-Ptt-103736	Puccinia triticina	41.91	5.00e-95	342.00
IUUC-Rno-105270	Rattus norvegicus	92.60	0.00e+00	1306.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.84	5.00e-69	256.00
IUUC-Sha-106819	Sarcophilus harrisii	91.23	0.00e+00	1375.00
IUUC-Spo-108271	Schizosaccharomyces pombe	32.63	1.00e-85	311.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	31.23	3.00e-84	306.00
IUUC-Sar-113134	Sorex araneus	86.58	0.00e+00	1249.00
IUUC-Ssc-115441	Sus scrofa	96.85	0.00e+00	1413.00
IUUC-Tgu-117166	Taeniopygia guttata	85.34	0.00e+00	1253.00
IUUC-Tsy-118898	Tarsius syrichta	82.13	0.00e+00	1129.00
IUUC-Tre-122108	Trichoderma reesei	39.34	1.00e-89	324.00
IUUC-Tvi-122644	Trichoderma virens	39.92	6.00e-95	342.00
IUUC-Tme-127004	Tuber melanosporum	34.86	3.00e-102	367.00
IUUC-Tbe-127292	Tupaia belangeri	79.32	0.00e+00	1079.00
IUUC-Ttr-128352	Tursiops truncatus	92.88	0.00e+00	1357.00
IUUC-Vda-129969	Verticillium dahliae	40.88	2.00e-92	334.00
IUUC-Vpa-130218	Vicugna pacos	95.18	0.00e+00	1021.00
IUUC-Xtr-132594	Xenopus tropicalis	80.00	0.00e+00	1169.00
IUUC-Xma-134157	Xiphophorus maculatus	75.46	0.00e+00	1041.00
IUUC-Yli-134470	Yarrowia lipolytica	35.15	2.00e-76	280.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence