iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058691

Ensembl Protein ID

AES67037

UniProt Accession

G7ITP8; G7ITP8_MEDTR

Genbank Protein ID

AES67037.1

Protein Name

Protein HIRA

Genbank Nucleotide ID

CM001218

Gene Name

MTR_2g086140

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_2g086140	AES67037	AES67037

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.50e-20	72.3	123	160
UBD/Beta-Prp	3.30e-41	142.9	12	208

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH+++v +l++ +d   l+sGs D+ti++W+++ g ++
   Q: 123  GHSADVVDLNWsPDdSSLASGSLDNTIHIWNMTNGICT 160
           8***********77799****************99886 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvw.................dl 81
           +  +i ++++ p++  +atg+ d+++++w++++  +           l++l +h + v++v++ ++g + ++gs+D++i +                  d+
   Q: 12   EGMQIFSIDVQPSGLRFATGGGDHKVRIWNMKSLGAdmesldtserlLATLRDHFGSVNCVRWAKHGRFVASGSDDQAILIHerkpgsgttefgsgeppDI 112
           5566778999**********************977799********************************************9998888888888888888 PP
   S: 82   stgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           ++ k v+tl+gh+++v++l++sp++++l+sGs d+ti++w++ +g c   +l+gh+++v +v+++p g+ ++s s+D+tv +W+ +  +l ++  g h
   Q: 113  ENWKVVMTLRGHSADVVDLNWSPDDSSLASGSLDNTIHIWNMTNGICTA-VLRGHSSLVKGVAWDPIGSFIASQSDDKTVIIWRTSDWSLAHRTDG-H 208
           8***********************************************9.*********************************9988888887766.4 PP

Organism

Medicago truncatula

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MIAEKPSWLR HEGMQIFSID VQPSGLRFAT GGGDHKVRIW NMKSLGADME SLDTSERLLA 60
TLRDHFGSVN CVRWAKHGRF VASGSDDQAI LIHERKPGSG TTEFGSGEPP DIENWKVVMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTGTTTTT GTTTTCCACC TTTCAAAGAA AATTGATAAA CCCTTCTTGA GTGTACATGT 60
GTAAAATTCA ATAAAATTCA GATTCTGGGA AATCATTACG ACCAATTTGC GTAGGAATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

mtr:MTR_2g086140

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004733	Anolis carolinensis	36.75	2.00e-83	303.00
IUUC-Ago-007766	Ashbya gossypii	29.71	1.00e-60	228.00
IUUC-Acl-008104	Aspergillus clavatus	30.73	1.00e-67	250.00
IUUC-Afl-008591	Aspergillus flavus	25.14	4.00e-85	309.00
IUUC-Aor-010119	Aspergillus oryzae	25.14	2.00e-85	310.00
IUUC-Bci-013795	Botrytis cinerea	32.12	2.00e-70	259.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	36.32	2.00e-73	270.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	34.51	7.00e-64	238.00
IUUC-Cne-026891	Cryptococcus neoformans	40.78	4.00e-81	295.00
IUUC-Dre-027655	Danio rerio	35.34	3.00e-83	302.00
IUUC-Dse-031334	Dothistroma septosporum	25.69	7.00e-90	325.00
IUUC-Fox-037906	Fusarium oxysporum	34.42	6.00e-67	248.00
IUUC-Fso-038409	Fusarium solani	34.74	8.00e-65	241.00
IUUC-Gmo-039151	Gadus morhua	39.27	1.00e-79	290.00
IUUC-Ggr-040016	Gaeumannomyces graminis	33.19	3.00e-67	249.00
IUUC-Gac-041405	Gasterosteus aculeatus	35.01	4.00e-79	289.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	41.46	2.00e-60	225.00
IUUC-Lma-053237	Leptosphaeria maculans	33.49	1.00e-65	244.00
IUUC-Meu-055914	Macropus eugenii	40.00	1.00e-52	201.00
IUUC-Mor-057090	Magnaporthe oryzae	34.96	2.00e-66	247.00
IUUC-Mpo-057364	Magnaporthe poae	33.19	6.00e-67	248.00
IUUC-Ncr-068842	Neurospora crassa	35.78	3.00e-69	256.00
IUUC-Opr-070808	Ochotona princeps	40.30	3.00e-51	196.00
IUUC-Ont-072105	Oreochromis niloticus	35.47	1.00e-79	290.00
IUUC-Ola-087302	Oryzias latipes	33.93	8.00e-78	285.00
IUUC-Pno-094985	Phaeosphaeria nodorum	30.07	5.00e-56	212.00
IUUC-Pgr-103660	Puccinia graminis	35.95	1.00e-61	231.00
IUUC-Ptt-103900	Puccinia triticina	36.49	2.00e-61	230.00
IUUC-Pte-104209	Pyrenophora teres	33.41	8.00e-69	254.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	33.41	5.00e-68	252.00
IUUC-Sce-106291	Saccharomyces cerevisiae	33.90	2.00e-65	243.00
IUUC-Tre-121887	Trichoderma reesei	31.56	3.00e-58	219.00
IUUC-Tvi-122262	Trichoderma virens	33.73	6.00e-58	218.00
IUUC-Tbe-127350	Tupaia belangeri	35.36	3.00e-47	183.00
IUUC-Vda-129844	Verticillium dahliae	33.65	7.00e-66	245.00
IUUC-Yli-134424	Yarrowia lipolytica	35.53	2.00e-64	240.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence