iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121765

Ensembl Protein ID

EOY33478

UniProt Accession

A0A061GVM4; A0A061GVM4_THECC

Genbank Protein ID

EOY33478.1

Protein Name

Protein HIRA

Genbank Nucleotide ID

CM001887

Gene Name

TCM_041451

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_041451	EOY33479	EOY33479
TCM_041451	EOY33478	EOY33478

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.00e-23	81.2	123	160
UBD/Beta-Prp	6.60e-41	141.3	11	208

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHt++v +l++ +d  +l+sGs D+ti++W+++ g ++
   Q: 123  GHTADVVDLNWsPDdSILASGSLDNTIHIWNMSNGICT 160
           8***********77799**************9998886 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvw.................d 80
           h+  +i ++++ p++  +atg+ d+++++w++++              l++l +h + v++v++ ++g + ++gs+D++i +                  d
   Q: 11   HEGMQIFSIDVQPGGLRFATGGGDHKVRIWNMKSVGRdlendestqrlLATLRDHFGSVNCVRWAKHGRFVASGSDDQVILIHerkpgsgttefgsgeppD 111
           56667788999*********************9976699********************************************888888888888888888 PP
   S: 81   lstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           +++ k  +tl+gh+++v++l++sp+++ l+sGs d+ti++w++++g c   +l+gh+++v +v+++p g+ ++s s+D+tv +W+ +  +l ++ +g h
   Q: 112  VENWKVAMTLRGHTADVVDLNWSPDDSILASGSLDNTIHIWNMSNGICTA-VLRGHSSLVKGVAWDPIGSFIASQSDDKTVIIWRTSDWSLAHRTEG-H 208
           88************************************************.**********************************988888888877.4 PP

Organism

Theobroma cacao

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MIAEKPSWVR HEGMQIFSID VQPGGLRFAT GGGDHKVRIW NMKSVGRDLE NDESTQRLLA 60
TLRDHFGSVN CVRWAKHGRF VASGSDDQVI LIHERKPGSG TTEFGSGEPP DVENWKVAMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTAAGGGTC ACAAAGATTA ATCCTTTATT TTTCTTTTTT CTTTTAAATA CATTGTTCTC 60
TGTTGCAGTC TTCCGTATCG AAGACCCTTC CTCACAATCT TCTAAGAAAG AATTTTGACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	68.13	0.00e+00	1382.00
IUUC-Aml-001723	Ailuropoda melanoleuca	41.41	1.00e-80	294.00
IUUC-Atr-003132	Amborella trichopoda	70.29	0.00e+00	1386.00
IUUC-Apl-003197	Anas platyrhynchos	35.17	6.00e-81	295.00
IUUC-Aca-004733	Anolis carolinensis	37.07	4.00e-86	311.00
IUUC-Aly-005446	Arabidopsis lyrata	72.26	0.00e+00	1380.00
IUUC-Ath-007627	Arabidopsis thaliana	70.20	0.00e+00	1370.00
IUUC-Ago-007766	Ashbya gossypii	30.53	2.00e-60	226.00
IUUC-Acl-008104	Aspergillus clavatus	31.24	3.00e-69	256.00
IUUC-Afl-008591	Aspergillus flavus	31.62	1.00e-67	250.00
IUUC-Afu-008781	Aspergillus fumigatus	34.84	2.00e-62	233.00
IUUC-Ani-009272	Aspergillus nidulans	29.12	1.00e-54	207.00
IUUC-Ang-009655	Aspergillus niger	32.32	3.00e-68	253.00
IUUC-Aor-010119	Aspergillus oryzae	34.03	1.00e-67	251.00
IUUC-Ate-010530	Aspergillus terreus	28.26	1.00e-54	207.00
IUUC-Bgr-012237	Blumeria graminis	34.45	1.00e-65	244.00
IUUC-Bta-013320	Bos taurus	37.17	2.00e-83	303.00
IUUC-Bci-013795	Botrytis cinerea	32.65	2.00e-73	270.00
IUUC-Bdi-014075	Brachypodium distachyon	71.09	0.00e+00	1410.00
IUUC-Bol-016440	Brassica oleracea	69.73	0.00e+00	1370.00
IUUC-Bra-016651	Brassica rapa	69.23	0.00e+00	1331.00
IUUC-Cel-018692	Caenorhabditis elegans	28.75	2.00e-45	177.00
IUUC-Cja-018987	Callithrix jacchus	35.71	8.00e-73	268.00
IUUC-Cfa-020132	Canis familiaris	41.09	8.00e-81	294.00
IUUC-Cpo-021484	Cavia porcellus	41.84	5.00e-85	308.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	36.83	7.00e-74	271.00
IUUC-Csa-023081	Chlorocebus sabaeus	37.92	3.00e-86	312.00
IUUC-Cin-025182	Ciona intestinalis	36.43	3.00e-82	299.00
IUUC-Csv-026154	Ciona savignyi	35.76	6.00e-81	295.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	26.10	1.00e-82	300.00
IUUC-Cne-026891	Cryptococcus neoformans	40.04	7.00e-82	297.00
IUUC-Cme-027349	Cyanidioschyzon merolae	28.36	1.00e-52	201.00
IUUC-Dre-027655	Danio rerio	36.16	7.00e-85	308.00
IUUC-Dno-029557	Dasypus novemcinctus	36.05	4.00e-68	252.00
IUUC-Dor-030687	Dipodomys ordii	37.43	3.00e-64	239.00
IUUC-Dse-031334	Dothistroma septosporum	31.60	1.00e-68	254.00
IUUC-Dme-031746	Drosophila melanogaster	39.61	8.00e-85	308.00
IUUC-Ete-032384	Echinops telfairi	33.20	2.00e-61	229.00
IUUC-Eca-033430	Equus caballus	36.76	1.00e-81	297.00
IUUC-Fca-036121	Felis catus	41.28	3.00e-82	299.00
IUUC-Fal-036817	Ficedula albicollis	36.27	4.00e-80	292.00
IUUC-Fox-037906	Fusarium oxysporum	32.11	6.00e-70	258.00
IUUC-Fso-038409	Fusarium solani	32.82	1.00e-68	254.00
IUUC-Gmo-039151	Gadus morhua	40.84	6.00e-82	298.00
IUUC-Ggr-040016	Gaeumannomyces graminis	35.11	5.00e-67	248.00
IUUC-Gga-040936	Gallus gallus	36.02	2.00e-84	306.00
IUUC-Gac-041405	Gasterosteus aculeatus	39.90	2.00e-78	286.00
IUUC-Gma-044252	Glycine max	77.76	0.00e+00	1628.00
IUUC-Ggo-045430	Gorilla gorilla	37.92	3.00e-86	312.00
IUUC-Hsa-046442	Homo sapiens	37.92	3.00e-86	312.00
IUUC-Hvu-047587	Hordeum vulgare	68.16	0.00e+00	1320.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	41.77	9.00e-63	232.00
IUUC-Kpa-049145	Komagataella pastoris	32.38	2.00e-59	223.00
IUUC-Lch-050474	Latimeria chalumnae	36.31	2.00e-79	290.00
IUUC-Lpe-051209	Leersia perrieri	68.24	0.00e+00	1353.00
IUUC-Loc-052119	Lepisosteus oculatus	34.90	5.00e-80	291.00
IUUC-Lma-053237	Leptosphaeria maculans	32.69	1.00e-63	237.00
IUUC-Laf-053718	Loxodonta africana	37.65	6.00e-86	311.00
IUUC-Mcc-055621	Macaca mulatta	35.90	7.00e-73	268.00
IUUC-Meu-055914	Macropus eugenii	39.31	2.00e-53	203.00
IUUC-Mor-057090	Magnaporthe oryzae	33.80	4.00e-66	246.00
IUUC-Mpo-057364	Magnaporthe poae	29.46	1.00e-67	250.00
IUUC-Mtr-057744	Medicago truncatula	79.96	0.00e+00	1597.00
IUUC-Mla-058914	Melampsora laricipopulina	38.17	2.00e-65	243.00
IUUC-Mga-060181	Meleagris gallopavo	35.60	6.00e-80	291.00
IUUC-Mvi-060432	Microbotryum violaceum	32.74	1.00e-57	218.00
IUUC-Mmr-060871	Microcebus murinus	37.72	1.00e-85	311.00
IUUC-Mdo-062301	Monodelphis domestica	36.16	4.00e-84	305.00
IUUC-Mmu-063888	Mus musculus	37.72	7.00e-86	311.00
IUUC-Mac-064768	Musa acuminata	72.54	0.00e+00	1373.00
IUUC-Mpu-066732	Mustela putorius furo	41.41	7.00e-81	295.00
IUUC-Mlu-067542	Myotis lucifugus	37.00	2.00e-82	300.00
IUUC-Nfi-068396	Neosartorya fischeri	34.59	8.00e-62	231.00
IUUC-Ncr-068842	Neurospora crassa	27.14	3.00e-86	313.00
IUUC-Nle-070156	Nomascus leucogenys	37.92	4.00e-86	312.00
IUUC-Opr-070808	Ochotona princeps	40.68	3.00e-52	199.00
IUUC-Ont-072105	Oreochromis niloticus	36.16	1.00e-81	297.00
IUUC-Ocu-074962	Oryctolagus cuniculus	36.34	3.00e-81	296.00
IUUC-Oba-075178	Oryza barthii	71.38	0.00e+00	1342.00
IUUC-Obr-076399	Oryza brachyantha	71.19	0.00e+00	1375.00
IUUC-Ogu-078797	Oryza glumaepatula	71.38	0.00e+00	1342.00
IUUC-Oin-080085	Oryza indica	70.87	0.00e+00	1261.00
IUUC-Olo-081048	Oryza longistaminata	88.85	9.00e-172	597.00
IUUC-Ome-081324	Oryza meridionalis	71.28	0.00e+00	1341.00
IUUC-Oni-082548	Oryza nivara	71.18	0.00e+00	1340.00
IUUC-Opu-084008	Oryza punctata	79.15	0.00e+00	773.00
IUUC-Oru-084339	Oryza rufipogon	71.38	0.00e+00	1342.00
IUUC-Osa-085782	Oryza sativa	71.38	0.00e+00	1342.00
IUUC-Ola-087302	Oryzias latipes	34.94	5.00e-77	281.00
IUUC-Olu-087611	Ostreococcus lucimarinus	42.66	5.00e-118	417.00
IUUC-Oga-087935	Otolemur garnettii	37.17	1.00e-81	296.00
IUUC-Oar-089229	Ovis aries	33.00	8.00e-65	241.00
IUUC-Ptr-090715	Pan troglodytes	37.92	3.00e-86	312.00
IUUC-Pan-092318	Papio anubis	37.10	4.00e-82	298.00
IUUC-Psi-094053	Pelodiscus sinensis	35.61	2.00e-80	293.00
IUUC-Pno-094985	Phaeosphaeria nodorum	31.16	6.00e-58	218.00
IUUC-Ppa-095499	Physcomitrella patens	51.34	0.00e+00	930.00
IUUC-Pfo-096857	Poecilia formosa	35.89	3.00e-78	286.00
IUUC-Pab-098047	Pongo abelii	37.92	3.00e-86	312.00
IUUC-Pop-099587	Populus trichocarpa	80.38	0.00e+00	1655.00
IUUC-Pca-100558	Procavia capensis	48.19	3.00e-48	186.00
IUUC-Ppe-101261	Prunus persica	81.22	0.00e+00	1587.00
IUUC-Pva-102683	Pteropus vampyrus	37.52	3.00e-83	302.00
IUUC-Pgr-103660	Puccinia graminis	37.03	3.00e-62	232.00
IUUC-Ptt-103900	Puccinia triticina	37.03	4.00e-62	232.00
IUUC-Pte-104209	Pyrenophora teres	33.88	2.00e-70	259.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	33.88	2.00e-69	257.00
IUUC-Rno-105566	Rattus norvegicus	38.12	2.00e-86	313.00
IUUC-Sce-106291	Saccharomyces cerevisiae	31.77	3.00e-67	249.00
IUUC-Sha-107514	Sarcophilus harrisii	33.67	2.00e-69	256.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	33.20	5.00e-71	261.00
IUUC-Spo-108162	Schizosaccharomyces pombe	32.89	2.00e-72	266.00
IUUC-Smo-109186	Selaginella moellendorffii	50.71	0.00e+00	922.00
IUUC-Sit-109980	Setaria italica	71.61	0.00e+00	1400.00
IUUC-Sly-111547	Solanum lycopersicum	72.90	0.00e+00	1494.00
IUUC-Stu-112705	Solanum tuberosum	73.47	0.00e+00	1499.00
IUUC-Sar-113222	Sorex araneus	35.12	6.00e-75	275.00
IUUC-Sbi-114272	Sorghum bicolor	70.60	0.00e+00	1360.00
IUUC-Sre-115061	Sporisorium reilianum	37.53	5.00e-71	261.00
IUUC-Ssc-116364	Sus scrofa	36.55	2.00e-81	296.00
IUUC-Tgu-116645	Taeniopygia guttata	35.86	7.00e-80	291.00
IUUC-Tru-117590	Takifugu rubripes	36.75	1.00e-85	310.00
IUUC-Tsy-119212	Tarsius syrichta	41.67	3.00e-69	256.00
IUUC-Tni-119915	Tetraodon nigroviridis	36.35	4.00e-84	305.00
IUUC-Tre-121887	Trichoderma reesei	26.43	3.00e-77	283.00
IUUC-Tvi-122262	Trichoderma virens	33.73	1.00e-59	224.00
IUUC-Tae-123009	Triticum aestivum	61.64	0.00e+00	844.00
IUUC-Tur-126483	Triticum urartu	68.82	0.00e+00	1398.00
IUUC-Tme-127202	Tuber melanosporum	28.71	7.00e-48	185.00
IUUC-Tbe-127350	Tupaia belangeri	34.40	5.00e-48	185.00
IUUC-Ttr-129077	Tursiops truncatus	32.85	6.00e-71	261.00
IUUC-Uma-129465	Ustilago maydis	37.44	3.00e-73	269.00
IUUC-Vda-129844	Verticillium dahliae	28.78	1.00e-70	260.00
IUUC-Vvi-131397	Vitis vinifera	80.62	0.00e+00	1659.00
IUUC-Xtr-132057	Xenopus tropicalis	35.56	4.00e-84	305.00
IUUC-Xma-134139	Xiphophorus maculatus	38.48	1.00e-65	243.00
IUUC-Yli-134424	Yarrowia lipolytica	34.60	2.00e-64	239.00
IUUC-Zma-135839	Zea mays	70.84	0.00e+00	1380.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence