iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132348

Ensembl Protein ID

ENSXETP00000041302.3

UniProt Accession

F7BND1; F7BND1_XENTR

Genbank Protein ID

ENSXETP00000041302

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAMC01031914

Gene Name

ing2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000019052.3	ENSXETT00000041302.3	ENSXETP00000041302.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.70e-09	36.0	272	318

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C+ ewfH+ C++l+    +p+ + w+Cp+Cr
   Q: 272  TYC-LCNQVSYGE--MIGCDNdeCTiEWFHFSCVGLT---YKPKGK-WYCPDCR 318
           69*.*******99..******9***9***********...888886.******8 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MRPERESSSG VSTLLPGQEP PVLAPPPPLR SASVGGAWSL SLCFGITRSR CSAKCLCWGT 60
MLGQQQQHLH YSPGSSAAED GQLVSYVEEY LECVESLPLE IQRSVTLLRE IDSQYREALK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGCCTG AGCGAGAGAG CAGTAGTGGA GTTAGCACGT TACTACCGGG GCAGGAACCT 60
CCTGTGCTAG CTCCGCCCCC TCCTCTTCGA TAACTCCTCA GCAGTGCGAG TGTGGGGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	70.00	2.00e-82	298.00
IUUC-Aca-004990	Anolis carolinensis	71.21	5.00e-86	310.00
IUUC-Acl-008091	Aspergillus clavatus	58.21	8.00e-19	89.00
IUUC-Bta-012721	Bos taurus	69.26	2.00e-81	295.00
IUUC-Cja-018960	Callithrix jacchus	73.15	4.00e-74	270.00
IUUC-Cfa-020869	Canis familiaris	69.86	8.00e-83	299.00
IUUC-Cpo-021414	Cavia porcellus	68.57	2.00e-80	291.00
IUUC-Csa-023304	Chlorocebus sabaeus	70.36	2.00e-75	275.00
IUUC-Cne-027005	Cryptococcus neoformans	46.97	3.00e-15	75.90
IUUC-Dre-028562	Danio rerio	60.89	6.00e-78	283.00
IUUC-Dno-029945	Dasypus novemcinctus	73.15	2.00e-82	298.00
IUUC-Dor-030141	Dipodomys ordii	69.29	6.00e-80	290.00
IUUC-Dse-031323	Dothistroma septosporum	63.64	5.00e-19	89.40
IUUC-Ete-032709	Echinops telfairi	68.55	1.00e-87	315.00
IUUC-Eca-033432	Equus caballus	72.76	5.00e-81	293.00
IUUC-Eeu-035285	Erinaceus europaeus	76.10	2.00e-68	251.00
IUUC-Fca-036467	Felis catus	71.98	3.00e-80	291.00
IUUC-Gmo-038748	Gadus morhua	56.36	4.00e-80	290.00
IUUC-Gac-041403	Gasterosteus aculeatus	58.48	6.00e-83	300.00
IUUC-Hsa-045837	Homo sapiens	70.36	2.00e-75	275.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	69.29	2.00e-81	295.00
IUUC-Lch-049965	Latimeria chalumnae	71.65	2.00e-86	311.00
IUUC-Lma-053234	Leptosphaeria maculans	56.90	7.00e-17	82.40
IUUC-Mcc-055155	Macaca mulatta	75.86	2.00e-54	204.00
IUUC-Meu-056470	Macropus eugenii	73.62	1.00e-87	315.00
IUUC-Mga-059570	Meleagris gallopavo	75.34	3.00e-76	277.00
IUUC-Mmr-061385	Microcebus murinus	70.36	2.00e-75	275.00
IUUC-Mdo-062144	Monodelphis domestica	73.23	3.00e-87	314.00
IUUC-Mmu-063215	Mus musculus	70.11	4.00e-82	297.00
IUUC-Mpu-065749	Mustela putorius furo	72.38	4.00e-73	267.00
IUUC-Nle-069968	Nomascus leucogenys	75.79	2.00e-61	228.00
IUUC-Ont-071524	Oreochromis niloticus	58.42	4.00e-82	297.00
IUUC-Ocu-074870	Oryctolagus cuniculus	69.26	3.00e-81	294.00
IUUC-Oga-088336	Otolemur garnettii	69.82	5.00e-75	273.00
IUUC-Oar-090136	Ovis aries	68.90	2.00e-81	295.00
IUUC-Ptr-091348	Pan troglodytes	75.79	2.00e-61	228.00
IUUC-Pan-092819	Papio anubis	70.36	2.00e-75	275.00
IUUC-Pfo-096633	Poecilia formosa	57.63	5.00e-75	273.00
IUUC-Pab-098346	Pongo abelii	70.00	5.00e-75	273.00
IUUC-Pca-100278	Procavia capensis	71.65	8.00e-86	309.00
IUUC-Pva-103190	Pteropus vampyrus	72.76	3.00e-81	294.00
IUUC-Pte-104284	Pyrenophora teres	55.17	5.00e-17	83.20
IUUC-Pyt-104787	Pyrenophora triticirepentis	58.62	3.00e-17	83.60
IUUC-Rno-104940	Rattus norvegicus	71.98	2.00e-80	291.00
IUUC-Sha-107533	Sarcophilus harrisii	74.02	4.00e-89	320.00
IUUC-Sar-113630	Sorex araneus	74.63	3.00e-67	247.00
IUUC-Ssc-115734	Sus scrofa	72.76	3.00e-81	294.00
IUUC-Tsy-119494	Tarsius syrichta	75.79	2.00e-61	228.00
IUUC-Tni-120100	Tetraodon nigroviridis	59.00	3.00e-70	258.00
IUUC-Tvi-122341	Trichoderma virens	64.29	3.00e-17	80.90
IUUC-Ttr-128442	Tursiops truncatus	75.61	6.00e-68	249.00
IUUC-Uma-129581	Ustilago maydis	58.33	9.00e-21	95.10
IUUC-Vpa-130063	Vicugna pacos	70.36	2.00e-82	298.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence