iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049973

Ensembl Protein ID

ENSLACP00000011172.1

UniProt Accession

H3ANF1; H3ANF1_LATCH

Genbank Protein ID

ENSLACP00000011172

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01122861

Gene Name

LLGL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000009831.1	ENSLACT00000011256.1	ENSLACP00000011172.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-06	28.4	427	450

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 11   f....sd.tllvsGsdDgtikvWD 29
                +  +ll++G  Dgt++ WD
   Q: 427  IapdpPQrDLLLTGHEDGTVRFWD 450
           3545444689************** PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MKRFRRHGTD LLRERIKQDL FQFSKTVEHG FPHQPSALGY CPTLQLMAIG TRSGALKIYG 60
APGVEIMGLH EENAAVTQIH FLPKQGRLVT LLEDNSLHLW ALRVHEGVSG LQEVDTFTLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCCGCCGG AAACCCAATC GCTGGGGGAG GGTTGGAGTT AGTAATCGGG TGGGAACTGG 60
AGTGGAGCCG GGAAAACCCG AGTTGGAAAG CCCGAGGCTG CGGGGGATTT AGGGGAAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000664--Lethal2_giant
IPR013577--LLGL2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2

Pfam

PF08366--LLGL

PRINTS

PR00962--LETHAL2GIANT

SMART

SM00320--WD40

Gene Ontology

GO:0007010--P:cytoskeleton organization
GO:0031581--P:hemidesmosome assembly
GO:0070121--P:Kupffer's vesicle development
GO:0044458--P:motile cilium assembly
GO:0030336--P:negative regulation of cell migration
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0048919--P:posterior lateral line neuromast development
GO:0045682--P:regulation of epidermis development
GO:0098773--P:skin epidermis development

KEGG

lcm:102351077

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000919	Aegilops tauschii	22.60	2.00e-11	64.70
IUUC-Aml-002413	Ailuropoda melanoleuca	69.60	0.00e+00	1395.00
IUUC-Atr-002583	Amborella trichopoda	25.24	8.00e-09	56.20
IUUC-Apl-003619	Anas platyrhynchos	74.76	0.00e+00	1467.00
IUUC-Aly-005770	Arabidopsis lyrata	21.84	2.00e-14	75.10
IUUC-Ath-007643	Arabidopsis thaliana	22.12	2.00e-15	78.60
IUUC-Acl-008044	Aspergillus clavatus	20.24	2.00e-04	42.00
IUUC-Afl-008612	Aspergillus flavus	20.74	6.00e-08	53.50
IUUC-Afu-008901	Aspergillus fumigatus	20.51	5.00e-07	50.40
IUUC-Ani-009223	Aspergillus nidulans	20.87	1.00e-06	48.50
IUUC-Ang-009861	Aspergillus niger	20.94	5.00e-10	60.10
IUUC-Aor-010078	Aspergillus oryzae	20.74	7.00e-08	53.10
IUUC-Ate-010462	Aspergillus terreus	21.02	1.00e-06	48.90
IUUC-Bgr-012214	Blumeria graminis	22.39	6.00e-07	49.70
IUUC-Bta-013249	Bos taurus	69.71	0.00e+00	1422.00
IUUC-Bci-013698	Botrytis cinerea	22.47	2.00e-06	48.10
IUUC-Bdi-015011	Brachypodium distachyon	24.04	6.00e-09	56.60
IUUC-Bol-015788	Brassica oleracea	21.10	9.00e-14	72.80
IUUC-Bra-017845	Brassica rapa	25.25	5.00e-10	60.50
IUUC-Cfa-020305	Canis familiaris	71.07	0.00e+00	1427.00
IUUC-Cpo-021354	Cavia porcellus	70.31	0.00e+00	1403.00
IUUC-Csa-024027	Chlorocebus sabaeus	70.87	0.00e+00	1405.00
IUUC-Cin-025693	Ciona intestinalis	45.74	0.00e+00	751.00
IUUC-Csv-025981	Ciona savignyi	47.08	0.00e+00	845.00
IUUC-Cgl-026432	Colletotrichum gloeosporioides	23.13	1.00e-07	52.40
IUUC-Dno-028910	Dasypus novemcinctus	69.62	0.00e+00	1356.00
IUUC-Dor-030976	Dipodomys ordii	68.31	0.00e+00	1360.00
IUUC-Dse-031263	Dothistroma septosporum	20.30	2.00e-06	48.10
IUUC-Ete-032938	Echinops telfairi	64.38	0.00e+00	755.00
IUUC-Eeu-035274	Erinaceus europaeus	70.58	0.00e+00	1320.00
IUUC-Fca-036585	Felis catus	69.71	0.00e+00	1392.00
IUUC-Fal-037603	Ficedula albicollis	74.27	0.00e+00	1459.00
IUUC-Fox-037853	Fusarium oxysporum	21.89	2.00e-09	58.20
IUUC-Fso-038327	Fusarium solani	21.26	2.00e-09	57.80
IUUC-Ggr-039723	Gaeumannomyces graminis	21.40	2.00e-12	67.80
IUUC-Gga-040222	Gallus gallus	72.33	0.00e+00	1440.00
IUUC-Gma-043398	Glycine max	26.64	5.00e-15	77.00
IUUC-Ggo-045203	Gorilla gorilla	70.29	0.00e+00	1387.00
IUUC-Hsa-045870	Homo sapiens	70.78	0.00e+00	1417.00
IUUC-Hvu-047650	Hordeum vulgare	23.44	2.00e-11	64.30
IUUC-Lpe-051115	Leersia perrieri	24.04	2.00e-10	62.00
IUUC-Lma-053029	Leptosphaeria maculans	23.14	1.00e-12	68.90
IUUC-Laf-053899	Loxodonta africana	69.92	0.00e+00	1418.00
IUUC-Mcc-055790	Macaca mulatta	71.07	0.00e+00	1403.00
IUUC-Mor-057129	Magnaporthe oryzae	19.47	1.00e-11	65.50
IUUC-Mpo-057585	Magnaporthe poae	21.52	4.00e-14	73.60
IUUC-Mtr-058362	Medicago truncatula	23.50	2.00e-13	71.60
IUUC-Mga-059850	Meleagris gallopavo	72.00	0.00e+00	1422.00
IUUC-Mmr-060930	Microcebus murinus	67.67	0.00e+00	1321.00
IUUC-Mdo-062588	Monodelphis domestica	70.38	0.00e+00	1471.00
IUUC-Mmu-064054	Mus musculus	69.06	0.00e+00	1393.00
IUUC-Mac-065436	Musa acuminata	26.52	8.00e-09	56.20
IUUC-Mpu-065729	Mustela putorius furo	69.71	0.00e+00	1401.00
IUUC-Mlu-066984	Myotis lucifugus	69.36	0.00e+00	1403.00
IUUC-Nfi-068318	Neosartorya fischeri	20.12	7.00e-06	46.60
IUUC-Ncr-068624	Neurospora crassa	19.49	2.00e-06	48.50
IUUC-Nle-069136	Nomascus leucogenys	69.78	0.00e+00	1367.00
IUUC-Oan-073438	Ornithorhynchus anatinus	64.28	0.00e+00	1135.00
IUUC-Ocu-074863	Oryctolagus cuniculus	69.77	0.00e+00	1356.00
IUUC-Oba-075180	Oryza barthii	23.56	9.00e-10	59.30
IUUC-Obr-076139	Oryza brachyantha	22.60	5.00e-09	57.00
IUUC-Ogl-077142	Oryza glaberrima	23.56	8.00e-10	59.70
IUUC-Ogu-079037	Oryza glumaepatula	22.97	5.00e-09	57.40
IUUC-Oin-079192	Oryza indica	23.56	7.00e-10	59.70
IUUC-Olo-080693	Oryza longistaminata	20.38	1.00e-13	72.40
IUUC-Oni-082885	Oryza nivara	23.56	7.00e-10	59.70
IUUC-Oru-084893	Oryza rufipogon	20.38	4.00e-13	70.50
IUUC-Osa-085916	Oryza sativa	23.56	7.00e-10	60.10
IUUC-Ola-086437	Oryzias latipes	65.94	0.00e+00	1259.00
IUUC-Oga-088270	Otolemur garnettii	69.84	0.00e+00	1414.00
IUUC-Ptr-091452	Pan troglodytes	71.56	0.00e+00	1382.00
IUUC-Pan-092654	Papio anubis	71.95	0.00e+00	1404.00
IUUC-Psi-093341	Pelodiscus sinensis	73.50	0.00e+00	1478.00
IUUC-Pno-095147	Phaeosphaeria nodorum	21.26	2.00e-06	48.10
IUUC-Pop-099276	Populus trichocarpa	26.72	4.00e-08	53.90
IUUC-Ppe-101236	Prunus persica	21.06	2.00e-11	64.70
IUUC-Pva-102373	Pteropus vampyrus	71.27	0.00e+00	1399.00
IUUC-Pte-104412	Pyrenophora teres	22.99	4.00e-14	73.90
IUUC-Pyt-104770	Pyrenophora triticirepentis	22.59	1.00e-13	72.00
IUUC-Rno-104988	Rattus norvegicus	69.12	0.00e+00	1399.00
IUUC-Sha-106592	Sarcophilus harrisii	67.06	0.00e+00	1348.00
IUUC-Sit-110386	Setaria italica	24.43	7.00e-11	63.20
IUUC-Sly-111338	Solanum lycopersicum	25.73	1.00e-11	63.50
IUUC-Stu-112417	Solanum tuberosum	25.73	7.00e-12	65.10
IUUC-Sbi-114175	Sorghum bicolor	22.39	5.00e-08	53.50
IUUC-Sre-115050	Sporisorium reilianum	20.50	2.00e-05	45.10
IUUC-Tgu-117381	Taeniopygia guttata	75.67	0.00e+00	1456.00
IUUC-Tca-121778	Theobroma cacao	22.14	3.00e-12	67.80
IUUC-Tre-122192	Trichoderma reesei	21.39	4.00e-09	57.40
IUUC-Tvi-122424	Trichoderma virens	20.44	4.00e-10	60.50
IUUC-Tae-125643	Triticum aestivum	21.53	2.00e-11	64.70
IUUC-Tur-126560	Triticum urartu	22.34	4.00e-09	57.00
IUUC-Tbe-127984	Tupaia belangeri	66.22	0.00e+00	704.00
IUUC-Vda-129843	Verticillium dahliae	22.26	2.00e-08	55.10
IUUC-Vvi-131567	Vitis vinifera	21.81	3.00e-12	67.80
IUUC-Xtr-132791	Xenopus tropicalis	67.49	0.00e+00	1365.00
IUUC-Yli-134491	Yarrowia lipolytica	21.07	3.00e-09	57.80
IUUC-Zma-135923	Zea mays	24.76	1.00e-08	55.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence