iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025789

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ribosome biogenesis protein WDR12 homolog

Genbank Nucleotide ID

EAAA01002968

Gene Name

LOC100187378

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000012967.2	ENSCINT00000024224.2	ENSCINP00000023978.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-37	125.9	345	379
UBD/Beta-Prp	3.10e-40	138.0	252	416

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtg 33
           H ++vt++++  +d ++lvsGs D+ +k+WD+r+ 
   Q: 345  HIGWVTSVHWapNDsHTLVSGSLDNCVKMWDTRSP 379
           999********988899**************9886 PP

UBD/Beta-Prp

   S: 85   kcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk..l 171
           +  +tl+gh++ v +l++    + + sGs+d tir+wd++t  + +      ++++ ++ ++  ++l+v+G +Dr vrlWd ++g+  +
   Q: 252  TAKVTLSGHTEVVSALTWLN-ENEICSGSWDHTIRIWDIDTAVEKS--HMRGMKSILSLDYSHLSRLVVTGNTDRHVRLWDPRSGEgaV 337
           44566666666666666666.6666666666666666666666665..45555566666666666666666666666666665443113 PP
   S: 172  lrtl.tgghtdsvyslsfdsng.kelvsgsldgtvklwdlqtgec.vrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           ++   t+ h + v+s+ + +n    lvsgsld+ vk+wd ++ +  ++ l++htd v sv+ s   ++++sg++D  ++ +
   Q: 338  VKCNlTS-HIGWVTSVHWAPNDsHTLVSGSLDNCVKMWDTRSPKApLYDLQAHTDKVMSVDWS-LPDIVASGGADCKVFTF 416
           3333243.6666666666666546666666666666666664443366666666666666666.66666666666666554 PP

Organism

Ciona intestinalis

Functional Description
(View)

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

Protein Sequence
(Fasta)

MAHFQIKLFT QQKQFSVTDN TFSVPGSSTC TELNDLVNKL LSEDKDESTR SDFDFLVNDE 60
FIRTSLVDHV ETKGLSSESV IDVEYLQRKQ APELKHSFQQ PDWISSIKTT EKFIITGSYD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCACT TCCAAATTAA ACTTTTCACA CAACAAAAAC AGTTTTCAGT TACTGATAAT 60
ACGTTTTCTG TACCTGGTAG CAGCACATGC ACAGAATTGA ATGATTTAGT GAACAAACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08154--NLE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000460--P:maturation of 5.8S rRNA
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000470--P:maturation of LSU-rRNA
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000532	Aegilops tauschii	31.30	4.00e-52	197.00
IUUC-Aml-001997	Ailuropoda melanoleuca	43.07	5.00e-91	326.00
IUUC-Atr-002544	Amborella trichopoda	30.37	1.00e-51	196.00
IUUC-Apl-003981	Anas platyrhynchos	45.45	6.00e-91	325.00
IUUC-Aca-004370	Anolis carolinensis	43.94	4.00e-100	356.00
IUUC-Aly-006455	Arabidopsis lyrata	28.16	2.00e-50	191.00
IUUC-Ath-006669	Arabidopsis thaliana	27.68	2.00e-46	178.00
IUUC-Ago-007864	Ashbya gossypii	26.80	9.00e-32	129.00
IUUC-Acl-008177	Aspergillus clavatus	26.99	1.00e-32	132.00
IUUC-Afl-008617	Aspergillus flavus	27.05	9.00e-32	130.00
IUUC-Afu-008752	Aspergillus fumigatus	26.81	6.00e-31	127.00
IUUC-Ani-009136	Aspergillus nidulans	26.96	3.00e-30	124.00
IUUC-Ang-009701	Aspergillus niger	28.12	2.00e-31	129.00
IUUC-Aor-009884	Aspergillus oryzae	26.81	3.00e-31	127.00
IUUC-Ame-011432	Astyanax mexicanus	43.43	4.00e-103	366.00
IUUC-Bgr-012218	Blumeria graminis	25.78	2.00e-27	115.00
IUUC-Bta-012829	Bos taurus	43.41	7.00e-96	342.00
IUUC-Bci-013953	Botrytis cinerea	27.03	4.00e-27	114.00
IUUC-Bdi-014351	Brachypodium distachyon	32.03	2.00e-47	182.00
IUUC-Bol-015618	Brassica oleracea	31.63	4.00e-46	177.00
IUUC-Bra-018095	Brassica rapa	31.17	5.00e-46	177.00
IUUC-Cel-018569	Caenorhabditis elegans	31.75	2.00e-53	201.00
IUUC-Cja-019468	Callithrix jacchus	43.41	5.00e-94	336.00
IUUC-Cfa-020471	Canis familiaris	41.97	1.00e-91	328.00
IUUC-Cpo-022260	Cavia porcellus	43.17	3.00e-93	333.00
IUUC-Cre-022614	Chlamydomonas reinhardtii	27.53	2.00e-36	145.00
IUUC-Csa-023989	Chlorocebus sabaeus	43.65	2.00e-94	337.00
IUUC-Cho-024426	Choloepus hoffmanni	43.77	8.00e-71	259.00
IUUC-Cne-027063	Cryptococcus neoformans	24.00	5.00e-26	110.00
IUUC-Dre-027907	Danio rerio	44.23	4.00e-103	366.00
IUUC-Dno-029225	Dasypus novemcinctus	43.41	2.00e-96	344.00
IUUC-Dor-031082	Dipodomys ordii	29.69	1.00e-50	192.00
IUUC-Dse-031308	Dothistroma septosporum	28.41	3.00e-33	134.00
IUUC-Dme-032189	Drosophila melanogaster	39.28	2.00e-89	321.00
IUUC-Ete-032247	Echinops telfairi	40.77	2.00e-87	315.00
IUUC-Eca-034285	Equus caballus	43.65	3.00e-96	343.00
IUUC-Eeu-035322	Erinaceus europaeus	40.75	3.00e-84	304.00
IUUC-Fca-036114	Felis catus	42.69	2.00e-95	340.00
IUUC-Fal-036891	Ficedula albicollis	45.51	5.00e-84	303.00
IUUC-Fox-037965	Fusarium oxysporum	27.25	1.00e-31	129.00
IUUC-Fso-038244	Fusarium solani	27.25	5.00e-33	134.00
IUUC-Gmo-039040	Gadus morhua	42.39	1.00e-103	368.00
IUUC-Ggr-040093	Gaeumannomyces graminis	22.50	2.00e-13	68.90
IUUC-Gga-040610	Gallus gallus	43.53	1.00e-99	355.00
IUUC-Gac-042117	Gasterosteus aculeatus	44.24	4.00e-105	373.00
IUUC-Gma-043967	Glycine max	30.79	8.00e-53	199.00
IUUC-Ggo-045179	Gorilla gorilla	43.41	3.00e-93	333.00
IUUC-Hsa-046114	Homo sapiens	43.65	2.00e-93	334.00
IUUC-Hvu-047331	Hordeum vulgare	32.58	1.00e-48	185.00
IUUC-Itr-048275	Ictidomys tridecemlineatus	43.65	3.00e-96	343.00
IUUC-Kpa-049304	Komagataella pastoris	26.61	1.00e-35	142.00
IUUC-Lch-050655	Latimeria chalumnae	37.87	6.00e-64	236.00
IUUC-Lpe-051675	Leersia perrieri	31.03	3.00e-52	197.00
IUUC-Loc-052868	Lepisosteus oculatus	41.36	2.00e-100	357.00
IUUC-Lma-053258	Leptosphaeria maculans	28.26	1.00e-31	130.00
IUUC-Laf-053993	Loxodonta africana	43.88	5.00e-97	346.00
IUUC-Mcc-055128	Macaca mulatta	35.97	2.00e-66	244.00
IUUC-Meu-056501	Macropus eugenii	42.20	1.00e-70	258.00
IUUC-Mor-057114	Magnaporthe oryzae	25.98	1.00e-27	116.00
IUUC-Mtr-058367	Medicago truncatula	33.33	2.00e-52	198.00
IUUC-Mla-059107	Melampsora laricipopulina	26.45	4.00e-33	134.00
IUUC-Mga-059745	Meleagris gallopavo	42.15	2.00e-96	344.00
IUUC-Mvi-060362	Microbotryum violaceum	28.39	5.00e-40	157.00
IUUC-Mdo-062257	Monodelphis domestica	42.12	4.00e-98	350.00
IUUC-Mmu-063546	Mus musculus	42.58	2.00e-96	344.00
IUUC-Mac-065540	Musa acuminata	29.88	4.00e-50	190.00
IUUC-Mpu-066284	Mustela putorius furo	43.41	4.00e-96	343.00
IUUC-Mlu-067241	Myotis lucifugus	42.45	7.00e-96	342.00
IUUC-Nfi-068260	Neosartorya fischeri	27.05	8.00e-32	130.00
IUUC-Ncr-068719	Neurospora crassa	24.24	1.00e-17	83.20
IUUC-Nle-068981	Nomascus leucogenys	43.17	5.00e-90	323.00
IUUC-Opr-071218	Ochotona princeps	40.30	2.00e-85	308.00
IUUC-Ont-071646	Oreochromis niloticus	43.44	2.00e-98	351.00
IUUC-Oan-073453	Ornithorhynchus anatinus	44.87	1.00e-105	375.00
IUUC-Ocu-074008	Oryctolagus cuniculus	42.69	3.00e-95	340.00
IUUC-Oba-075712	Oryza barthii	28.54	1.00e-38	152.00
IUUC-Obr-076721	Oryza brachyantha	30.96	6.00e-50	190.00
IUUC-Ogl-077229	Oryza glaberrima	32.51	2.00e-52	198.00
IUUC-Ogu-078977	Oryza glumaepatula	28.29	8.00e-39	153.00
IUUC-Oin-079683	Oryza indica	30.82	2.00e-52	198.00
IUUC-Olo-080291	Oryza longistaminata	28.62	2.00e-25	108.00
IUUC-Ome-081834	Oryza meridionalis	32.27	2.00e-53	201.00
IUUC-Oni-082507	Oryza nivara	30.94	3.00e-49	187.00
IUUC-Opu-083396	Oryza punctata	32.27	2.00e-52	199.00
IUUC-Oru-085220	Oryza rufipogon	30.26	7.00e-49	186.00
IUUC-Osa-085767	Oryza sativa	30.82	2.00e-52	198.00
IUUC-Ola-087420	Oryzias latipes	42.00	3.00e-98	350.00
IUUC-Olu-087740	Ostreococcus lucimarinus	29.91	2.00e-42	165.00
IUUC-Oga-088264	Otolemur garnettii	43.65	3.00e-94	337.00
IUUC-Oar-089335	Ovis aries	42.69	1.00e-94	338.00
IUUC-Ptr-091320	Pan troglodytes	43.65	2.00e-93	334.00
IUUC-Pan-092833	Papio anubis	43.65	4.00e-94	337.00
IUUC-Psi-093504	Pelodiscus sinensis	44.60	9.00e-99	352.00
IUUC-Pma-094189	Petromyzon marinus	42.34	6.00e-95	339.00
IUUC-Pno-094929	Phaeosphaeria nodorum	27.59	3.00e-29	121.00
IUUC-Ppa-095429	Physcomitrella patens	33.41	2.00e-59	221.00
IUUC-Pfo-096337	Poecilia formosa	42.86	5.00e-105	372.00
IUUC-Pab-097571	Pongo abelii	43.41	2.00e-93	334.00
IUUC-Pop-099977	Populus trichocarpa	30.33	8.00e-52	196.00
IUUC-Pca-100394	Procavia capensis	40.69	2.00e-81	294.00
IUUC-Ppe-101848	Prunus persica	30.31	2.00e-52	197.00
IUUC-Pva-102921	Pteropus vampyrus	35.40	1.00e-35	142.00
IUUC-Pgr-103637	Puccinia graminis	25.05	3.00e-32	131.00
IUUC-Ptt-103781	Puccinia triticina	26.55	2.00e-34	139.00
IUUC-Pte-104135	Pyrenophora teres	27.21	2.00e-29	123.00
IUUC-Pyt-104609	Pyrenophora triticirepentis	26.33	3.00e-31	127.00
IUUC-Rno-105114	Rattus norvegicus	43.17	8.00e-97	345.00
IUUC-Sce-106401	Saccharomyces cerevisiae	29.18	5.00e-38	150.00
IUUC-Sha-107122	Sarcophilus harrisii	42.03	6.00e-93	333.00
IUUC-Sja-107766	Schizosaccharomyces japonicus	26.65	1.00e-36	146.00
IUUC-Spo-108134	Schizosaccharomyces pombe	28.57	3.00e-39	154.00
IUUC-Ssl-108398	Sclerotinia sclerotiorum	27.57	2.00e-29	122.00
IUUC-Smo-108761	Selaginella moellendorffii	34.26	8.00e-58	216.00
IUUC-Sit-110311	Setaria italica	32.75	2.00e-52	198.00
IUUC-Sly-111023	Solanum lycopersicum	27.81	4.00e-45	174.00
IUUC-Stu-112778	Solanum tuberosum	30.09	8.00e-50	189.00
IUUC-Sar-113596	Sorex araneus	40.71	4.00e-72	263.00
IUUC-Sbi-114193	Sorghum bicolor	31.14	2.00e-50	192.00
IUUC-Sre-115002	Sporisorium reilianum	24.27	5.00e-16	77.80
IUUC-Ssc-116066	Sus scrofa	42.93	2.00e-94	337.00
IUUC-Tgu-117048	Taeniopygia guttata	45.99	4.00e-91	326.00
IUUC-Tsy-119573	Tarsius syrichta	25.00	4.00e-32	130.00
IUUC-Tni-119820	Tetraodon nigroviridis	43.17	7.00e-98	349.00
IUUC-Tca-121605	Theobroma cacao	29.45	3.00e-49	187.00
IUUC-Tre-121947	Trichoderma reesei	25.59	8.00e-31	126.00
IUUC-Tvi-122481	Trichoderma virens	25.59	2.00e-31	129.00
IUUC-Tae-123847	Triticum aestivum	31.30	4.00e-52	197.00
IUUC-Tur-126586	Triticum urartu	31.57	2.00e-50	191.00
IUUC-Tme-126900	Tuber melanosporum	28.27	4.00e-38	150.00
IUUC-Tbe-127736	Tupaia belangeri	33.00	7.00e-56	209.00
IUUC-Ttr-129041	Tursiops truncatus	38.66	4.00e-76	277.00
IUUC-Vpa-130260	Vicugna pacos	43.41	5.00e-96	343.00
IUUC-Vvi-131009	Vitis vinifera	27.34	4.00e-47	180.00
IUUC-Xtr-132083	Xenopus tropicalis	44.15	2.00e-97	347.00
IUUC-Xma-133094	Xiphophorus maculatus	42.86	1.00e-104	371.00
IUUC-Yli-134531	Yarrowia lipolytica	31.13	3.00e-10	58.50
IUUC-Zma-135509	Zea mays	31.20	4.00e-52	197.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence