iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028723

UUCD1 version

UUC-DaR-01260

Ensembl Protein ID

ENSDARP00000088166.3

UniProt Accession

Q6PH45; Q6PH45_DANRE

Genbank Protein ID

AAH56720.1; AAI54323.1

Protein Name

PRP4 pre-mRNA processing factor 4 homolog (Yeast); PRP4 pre-mRNA-processing factor 4 homolog (yeast)

Genbank Nucleotide ID

BX510338; BC154322

Gene Name

prpf4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000067639.3	ENSDART00000097395.3	ENSDARP00000088166.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.40e-39	132.0	390	428
UBD/Beta-Prp	1.20e-64	219.2	215	462

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH  ++++++f ++  ++++Gs+D+ +kvWDlr+ +++ 
   Q: 390  GHIKEIYSINFsPNgFHVATGSGDNACKVWDLRQRRCIY 428
           79999*******77799****************999975 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk........ilvtgseDrtikvwdlstgkcvht 89
           ++ +i+  +fsp+++ll+t+s++g  k+w+v + +l+r+l gh+  v a++f+p++          +++++ D+ +k+w+l++ +++  
   Q: 215  DDRPISYCQFSPNSKLLVTASWSGLCKLWKVPDCTLIRTLRGHNTNVGAISFHPQATltleesdvNMASCAADGSVKLWSLDSDEPIAD 303
           6789999************************************************999888999899********************** PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++gh+ +v  ++++psg +l ++  d   r+wdle ++++   ++gh++ v  +++hpdg+l  +G+lD++ r+Wdl+tg+++  l+g 
   Q: 304  IEGHSMRVARVTWHPSGRFLGTTCYDHSWRLWDLEVQEEIL-HQEGHSKGVHDLHFHPDGSLAGTGGLDSFARVWDLRTGRCVMFLEG- 390
           *****************************************.********************************************99. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriW 249
           h + +ys++f++ng+++++gs d+  k+wdl++ +c++t  +h++ v+sv+f  +++++l++g+ D++ +iW
   Q: 391  HIKEIYSINFSPNGFHVATGSGDNACKVWDLRQRRCIYTIPAHQNLVSSVKFQpNDGHYLLTGAYDNTAKIW 462
           *****************************************************77889************** PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSDEDEAPVV KRSRIFYGSL EEKEKERLSR EGTSTTAKDA VKAGIEAGHI NISSGESMEM 60
EERVSERQAE VLAEFERRKR ARQITVSTDD VEVKACLRAL GEPITLFGEG PAERRERLRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCGGATAT GACGACATAC TGTGCGCCGA GTAGCCCGCG TCGTGTGGTC GTGTTTGTGG 60
ATTTTATCAC AGCACTATCT TACAAAACAA GCTGCTTTTA AAGGAAGCTT CGTTTGTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR014906--PRP4-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08799--PRP4
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00500--SFM
SM00320--WD40

Gene Ontology

GO:0046540--C:U4/U6 x U5 tri-snRNP complex
GO:0030621--F:U4 snRNA binding
GO:0017070--F:U6 snRNA binding
GO:0043009--P:chordate embryonic development
GO:0009792--P:embryo development ending in birth or egg hatching
GO:0000398--P:mRNA splicing, via spliceosome
GO:0060041--P:retina development in camera-type eye

KEGG

dre:326944

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000771	Aegilops tauschii	44.39	3.00e-102	365.00
IUUC-Aml-001737	Ailuropoda melanoleuca	79.80	0.00e+00	849.00
IUUC-Atr-002828	Amborella trichopoda	42.01	3.00e-104	372.00
IUUC-Apl-003723	Anas platyrhynchos	79.80	0.00e+00	857.00
IUUC-Aca-004972	Anolis carolinensis	78.94	0.00e+00	811.00
IUUC-Aly-006531	Arabidopsis lyrata	43.37	1.00e-94	340.00
IUUC-Ath-007367	Arabidopsis thaliana	44.03	4.00e-110	392.00
IUUC-Ago-007893	Ashbya gossypii	31.42	2.00e-53	203.00
IUUC-Acl-008236	Aspergillus clavatus	39.04	1.00e-89	323.00
IUUC-Afl-008522	Aspergillus flavus	41.24	5.00e-101	361.00
IUUC-Afu-008904	Aspergillus fumigatus	39.12	8.00e-94	337.00
IUUC-Ani-009198	Aspergillus nidulans	40.62	5.00e-99	355.00
IUUC-Ang-009662	Aspergillus niger	42.95	1.00e-100	360.00
IUUC-Aor-009881	Aspergillus oryzae	41.24	4.00e-101	362.00
IUUC-Ate-010333	Aspergillus terreus	38.92	2.00e-88	319.00
IUUC-Ame-011697	Astyanax mexicanus	89.15	0.00e+00	906.00
IUUC-Bgr-012254	Blumeria graminis	40.69	1.00e-103	370.00
IUUC-Bta-012615	Bos taurus	80.00	0.00e+00	837.00
IUUC-Bci-013720	Botrytis cinerea	39.06	5.00e-100	358.00
IUUC-Bdi-014302	Brachypodium distachyon	44.50	4.00e-109	388.00
IUUC-Bol-015594	Brassica oleracea	42.42	2.00e-98	353.00
IUUC-Bra-017465	Brassica rapa	42.21	2.00e-98	353.00
IUUC-Cel-018632	Caenorhabditis elegans	45.82	7.00e-116	410.00
IUUC-Cja-019747	Callithrix jacchus	79.80	0.00e+00	852.00
IUUC-Cfa-020288	Canis familiaris	79.80	0.00e+00	851.00
IUUC-Cpo-021440	Cavia porcellus	78.26	0.00e+00	835.00
IUUC-Cre-022716	Chlamydomonas reinhardtii	44.82	2.00e-86	312.00
IUUC-Csa-023139	Chlorocebus sabaeus	81.98	1.00e-175	608.00
IUUC-Cho-024481	Choloepus hoffmanni	80.53	0.00e+00	754.00
IUUC-Cin-025106	Ciona intestinalis	60.79	0.00e+00	629.00
IUUC-Csv-026087	Ciona savignyi	59.17	0.00e+00	632.00
IUUC-Cgl-026538	Colletotrichum gloeosporioides	38.64	7.00e-95	342.00
IUUC-Cne-026793	Cryptococcus neoformans	40.20	8.00e-105	374.00
IUUC-Dno-029299	Dasypus novemcinctus	79.41	0.00e+00	847.00
IUUC-Dor-030345	Dipodomys ordii	53.36	6.00e-66	244.00
IUUC-Dse-031562	Dothistroma septosporum	38.00	2.00e-91	329.00
IUUC-Dme-031783	Drosophila melanogaster	50.36	6.00e-139	487.00
IUUC-Ete-032669	Echinops telfairi	79.01	0.00e+00	845.00
IUUC-Eca-033566	Equus caballus	79.80	0.00e+00	849.00
IUUC-Eeu-034524	Erinaceus europaeus	62.13	1.00e-157	549.00
IUUC-Fca-036215	Felis catus	79.80	0.00e+00	850.00
IUUC-Fal-037018	Ficedula albicollis	78.79	0.00e+00	719.00
IUUC-Fox-037936	Fusarium oxysporum	38.35	1.00e-85	310.00
IUUC-Fso-038366	Fusarium solani	38.94	3.00e-92	332.00
IUUC-Gmo-038966	Gadus morhua	70.03	8.00e-151	526.00
IUUC-Ggr-039942	Gaeumannomyces graminis	38.28	2.00e-86	313.00
IUUC-Gga-040797	Gallus gallus	79.96	0.00e+00	856.00
IUUC-Gac-042598	Gasterosteus aculeatus	72.16	0.00e+00	720.00
IUUC-Gma-044220	Glycine max	44.02	4.00e-103	369.00
IUUC-Ggo-044682	Gorilla gorilla	79.84	0.00e+00	845.00
IUUC-Hsa-045804	Homo sapiens	80.00	0.00e+00	852.00
IUUC-Hvu-047567	Hordeum vulgare	43.95	2.00e-98	352.00
IUUC-Itr-047882	Ictidomys tridecemlineatus	79.60	0.00e+00	850.00
IUUC-Kpa-049369	Komagataella pastoris	33.24	3.00e-61	229.00
IUUC-Lch-050074	Latimeria chalumnae	77.41	0.00e+00	800.00
IUUC-Lpe-051333	Leersia perrieri	43.33	9.00e-101	360.00
IUUC-Loc-052164	Lepisosteus oculatus	85.40	0.00e+00	899.00
IUUC-Lma-053088	Leptosphaeria maculans	36.92	8.00e-86	311.00
IUUC-Laf-053460	Loxodonta africana	79.80	0.00e+00	851.00
IUUC-Mcc-055859	Macaca mulatta	79.80	0.00e+00	850.00
IUUC-Meu-056134	Macropus eugenii	79.80	0.00e+00	847.00
IUUC-Mor-057251	Magnaporthe oryzae	36.90	3.00e-86	312.00
IUUC-Mpo-057375	Magnaporthe poae	40.80	1.00e-52	199.00
IUUC-Mtr-057656	Medicago truncatula	44.75	1.00e-95	343.00
IUUC-Mla-059145	Melampsora laricipopulina	41.32	7.00e-103	367.00
IUUC-Mga-059855	Meleagris gallopavo	79.25	0.00e+00	850.00
IUUC-Mvi-060372	Microbotryum violaceum	43.00	3.00e-97	349.00
IUUC-Mmr-060826	Microcebus murinus	79.80	0.00e+00	848.00
IUUC-Mdo-062119	Monodelphis domestica	79.84	0.00e+00	844.00
IUUC-Mmu-063351	Mus musculus	79.80	0.00e+00	850.00
IUUC-Mac-064846	Musa acuminata	42.50	1.00e-95	343.00
IUUC-Mpu-066006	Mustela putorius furo	79.80	0.00e+00	850.00
IUUC-Mlu-067398	Myotis lucifugus	79.80	0.00e+00	848.00
IUUC-Nfi-068399	Neosartorya fischeri	38.92	5.00e-100	358.00
IUUC-Ncr-068711	Neurospora crassa	37.29	2.00e-91	329.00
IUUC-Nle-069982	Nomascus leucogenys	79.80	0.00e+00	852.00
IUUC-Opr-070596	Ochotona princeps	79.60	0.00e+00	851.00
IUUC-Ont-072374	Oreochromis niloticus	80.20	0.00e+00	827.00
IUUC-Oan-073166	Ornithorhynchus anatinus	80.05	0.00e+00	676.00
IUUC-Ocu-074371	Oryctolagus cuniculus	79.60	0.00e+00	849.00
IUUC-Oba-075083	Oryza barthii	43.61	9.00e-104	370.00
IUUC-Obr-076405	Oryza brachyantha	43.33	5.00e-100	358.00
IUUC-Ogl-077683	Oryza glaberrima	43.61	1.00e-103	370.00
IUUC-Ogu-078486	Oryza glumaepatula	43.38	1.00e-102	367.00
IUUC-Oin-079679	Oryza indica	43.15	6.00e-105	375.00
IUUC-Olo-080243	Oryza longistaminata	42.61	2.00e-91	329.00
IUUC-Ome-081230	Oryza meridionalis	43.15	7.00e-105	374.00
IUUC-Oni-082961	Oryza nivara	43.15	1.00e-104	374.00
IUUC-Opu-083189	Oryza punctata	42.60	4.00e-102	365.00
IUUC-Oru-084353	Oryza rufipogon	43.22	1.00e-102	366.00
IUUC-Osa-085458	Oryza sativa	43.15	7.00e-105	374.00
IUUC-Ola-086940	Oryzias latipes	78.15	0.00e+00	822.00
IUUC-Olu-087580	Ostreococcus lucimarinus	34.91	2.00e-66	246.00
IUUC-Oga-088703	Otolemur garnettii	76.04	0.00e+00	801.00
IUUC-Oar-089829	Ovis aries	79.60	0.00e+00	834.00
IUUC-Ptr-090838	Pan troglodytes	80.00	0.00e+00	852.00
IUUC-Pan-092261	Papio anubis	79.45	0.00e+00	845.00
IUUC-Psi-093020	Pelodiscus sinensis	78.70	0.00e+00	855.00
IUUC-Pno-094858	Phaeosphaeria nodorum	36.64	6.00e-80	291.00
IUUC-Ppa-095531	Physcomitrella patens	43.70	5.00e-114	404.00
IUUC-Pfo-096812	Poecilia formosa	73.15	0.00e+00	736.00
IUUC-Pab-097805	Pongo abelii	71.09	0.00e+00	729.00
IUUC-Pop-100051	Populus trichocarpa	43.90	1.00e-103	370.00
IUUC-Pca-100152	Procavia capensis	79.80	0.00e+00	851.00
IUUC-Ppe-101244	Prunus persica	43.51	2.00e-105	375.00
IUUC-Pva-102529	Pteropus vampyrus	76.83	0.00e+00	810.00
IUUC-Pgr-103550	Puccinia graminis	36.82	4.00e-102	365.00
IUUC-Ptt-103951	Puccinia triticina	39.95	2.00e-81	296.00
IUUC-Pte-104151	Pyrenophora teres	37.27	5.00e-81	295.00
IUUC-Pyt-104571	Pyrenophora triticirepentis	38.13	3.00e-84	305.00
IUUC-Rno-105747	Rattus norvegicus	79.60	0.00e+00	848.00
IUUC-Sce-106418	Saccharomyces cerevisiae	34.29	3.00e-70	259.00
IUUC-Sha-107334	Sarcophilus harrisii	80.00	0.00e+00	848.00
IUUC-Sja-107794	Schizosaccharomyces japonicus	35.89	2.00e-74	273.00
IUUC-Spo-108189	Schizosaccharomyces pombe	36.24	3.00e-80	292.00
IUUC-Ssl-108550	Sclerotinia sclerotiorum	38.63	3.00e-98	352.00
IUUC-Smo-109578	Selaginella moellendorffii	43.97	2.00e-109	389.00
IUUC-Sit-110102	Setaria italica	43.64	3.00e-104	372.00
IUUC-Sly-111668	Solanum lycopersicum	43.72	6.00e-104	371.00
IUUC-Stu-111928	Solanum tuberosum	43.72	2.00e-104	373.00
IUUC-Sar-113266	Sorex araneus	70.50	0.00e+00	711.00
IUUC-Sbi-114134	Sorghum bicolor	42.95	5.00e-104	371.00
IUUC-Sre-115114	Sporisorium reilianum	42.31	1.00e-105	376.00
IUUC-Ssc-115443	Sus scrofa	79.80	0.00e+00	849.00
IUUC-Tgu-117157	Taeniopygia guttata	80.12	0.00e+00	818.00
IUUC-Tru-118587	Takifugu rubripes	80.16	0.00e+00	821.00
IUUC-Tsy-119157	Tarsius syrichta	81.03	0.00e+00	676.00
IUUC-Tni-120427	Tetraodon nigroviridis	80.79	0.00e+00	832.00
IUUC-Tca-121368	Theobroma cacao	44.03	2.00e-108	386.00
IUUC-Tre-122074	Trichoderma reesei	38.72	1.00e-90	327.00
IUUC-Tvi-122349	Trichoderma virens	37.79	8.00e-89	321.00
IUUC-Tae-125651	Triticum aestivum	44.29	1.00e-104	373.00
IUUC-Tur-126532	Triticum urartu	43.86	3.00e-92	332.00
IUUC-Tme-126951	Tuber melanosporum	40.84	5.00e-102	365.00
IUUC-Tbe-128136	Tupaia belangeri	72.87	0.00e+00	756.00
IUUC-Ttr-129169	Tursiops truncatus	80.54	7.00e-141	493.00
IUUC-Uma-129399	Ustilago maydis	42.64	1.00e-104	373.00
IUUC-Vda-129842	Verticillium dahliae	38.84	1.00e-95	343.00
IUUC-Vpa-130440	Vicugna pacos	79.80	0.00e+00	849.00
IUUC-Vvi-131075	Vitis vinifera	43.57	5.00e-104	372.00
IUUC-Xtr-132713	Xenopus tropicalis	47.36	1.00e-110	393.00
IUUC-Xma-133002	Xiphophorus maculatus	81.34	7.00e-180	622.00
IUUC-Yli-134569	Yarrowia lipolytica	36.48	4.00e-78	285.00
IUUC-Zma-135799	Zea mays	41.51	2.00e-102	366.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence