iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097908

Ensembl Protein ID

ENSPPYP00000012176.2

UniProt Accession

H2P1L5; H2P1L5_PONAB

Genbank Protein ID

ENSPPYP00000012176

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

ABGA01020931

Gene Name

HCK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000010900.2	ENSPPYT00000012655.2	ENSPPYP00000012176.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.40e-17	61.4	82	137

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            v +lydyea + ++L+++kGd++ v+   e++++W+k+ + ++gk+G +P+n+v++++
   Q: 82   IVVALYDYEAIHHEDLSFQKGDKMVVL---EESGEWWKARSLATGKEGYIPSNYVARVD 137
           689************************...99*************************97 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

LGGRSSCEDP GCPRDEERAP RMGCMRSKFL QVGGNTFSKS ETSANPHCPV YVPDPTSTIK 60
PGPNSNNSNT PGIREAGSED IIVVALYDYE AIHHEDLSFQ KGDKMVVLEE SGEWWKARSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGGGGGGC GCTCAAGCTG CGAGGATCCG GGCTGCCCGC GAGACGAGGA GCGGGCGCCC 60
AGGTGAGTGC CGTGCACAGG GGACCGGGAA TACCCGGCCC GCGAGGGGTC CCAGGAGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007861	Ashbya gossypii	51.22	2.00e-05	43.50
IUUC-Acl-008300	Aspergillus clavatus	40.00	1.00e-06	48.90
IUUC-Ang-009534	Aspergillus niger	37.93	4.00e-07	50.80
IUUC-Csa-024143	Chlorocebus sabaeus	77.67	0.00e+00	776.00
IUUC-Fox-037764	Fusarium oxysporum	48.00	2.00e-07	48.90
IUUC-Ggo-044570	Gorilla gorilla	79.28	0.00e+00	824.00
IUUC-Hsa-046378	Homo sapiens	79.28	0.00e+00	837.00
IUUC-Lma-053236	Leptosphaeria maculans	40.00	1.00e-06	48.50
IUUC-Mcc-055317	Macaca mulatta	77.62	0.00e+00	778.00
IUUC-Nfi-068406	Neosartorya fischeri	40.00	2.00e-06	48.50
IUUC-Nle-069222	Nomascus leucogenys	77.82	0.00e+00	768.00
IUUC-Ptr-090505	Pan troglodytes	84.25	0.00e+00	857.00
IUUC-Pan-092260	Papio anubis	77.82	0.00e+00	780.00
IUUC-Pno-094774	Phaeosphaeria nodorum	43.66	3.00e-08	55.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence