iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021798

Ensembl Protein ID

ENSCPOP00000013190.2

UniProt Accession

H0VRH6; H0VRH6_CAVPO

Genbank Protein ID

ENSCPOP00000013190

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02002140

Gene Name

WDR36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000014638.3	ENSCPOT00000014783.2	ENSCPOP00000013190.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-22	78.3	568	604
UBD/Beta-Prp	5.40e-61	206.3	237	528

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ ++++ f +d + l+s++ D+ i++WDl +g l
   Q: 568  GHQGQINDMTFsPDgRWLISAAMDCCIRIWDLPSGCL 604
           8***********99999***************99976 PP

UBD/Beta-Prp

   S: 11   svitcvkf.spdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvw....dlstgkcvhtlkgh 93
           ++it++ f +++ +++a+gs  g i +wd++++kl+ ++   h+ +++ ++f +++++lvt + D+++++w    +   g  ++   gh
   Q: 237  GPITSISFrTDGHPIMAAGSPCGHIGLWDLEDKKLINQMrNAHSTAIAGLTFLHREPLLVTNGADNAVRIWifdgPAGEGRLLRFRMGH 325
           689*****9999***************************99******************************7765555999999999** PP
   S: 94   edsvlslsfsp.sgdklvsGshdrtirvwdletgqclee..........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..... 166
           ++ ++s++++  +g+ ++s+s+d t++ + + +++  ++          ++++  + +++v+++p ++  + ++       Wd      
   Q: 326  SAPLTSIRYYGqNGQQILSASQDGTLQSFSTVHEKFNKSlghglinkkrVKRKGLQNTMSVRLPPITKFAAEAAR--ESD-WDGiiach 411
           *********99788***************9999988888999**9999966666666666666664444333332..222.44444442 PP
   S: 167  ...........ktgkllrtl...tgghtdsvysls...fdsngkelvsgsldgtvklwdlq....tgecvrtlnghtdnvksvrfspnd 234
                      +  ++   +   ++ +td+++ +    ++s g++ v g   gtv ++++q    +g    + ++h+  ++ v+++  +
   Q: 412  qgklscstwnyQKSTIGSYFlkpKELKTDDITATVsrdITSCGNFAVIGLSSGTVDVYNMQsgihRG-SFGKDQAHKGSIRGVAVDGLN 499
           11222222221333333333555444555555555455666669*****************555322.3777789************** PP
   S: 235  erlvsgssDgsiriWdlrsgdllktlqlh 263
           ++ ++++s+g +++W+ +++dl+++++l 
   Q: 500  QLTITAGSEGLLKFWNFKNKDLIHSVNLD 528
           ************************99985 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

VAEMECGMEG RTASALFAGF RALGLFSNDI PHVVRFSALK RRFYVTTCVG KSFHTYDVQK 60
LSLVAVSNSV PQDICCMAAD GRLVFAAYGN VFSAFARNKE VVHTFKGHKA EIQLLQPFGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGCGGAGA TGGAATGCGG CATGGAAGGC CGGACAGCCA GCGCGCTCTT CGCGGGGTTC 60
CGGGCCTTGG GGCTCTTTAG CAACGATATT CCACACGTGG TGCGGTTCAG CGCGCTGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR007319--SSU_processome_Utp21
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04192--Utp21
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0032040--C:small-subunit processome
GO:0003723--F:RNA binding
GO:0030516--P:regulation of axon extension
GO:0001895--P:retina homeostasis
GO:0006364--P:rRNA processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001096	Aegilops tauschii	36.13	7.00e-148	518.00
IUUC-Aml-002289	Ailuropoda melanoleuca	92.53	0.00e+00	1600.00
IUUC-Atr-002859	Amborella trichopoda	33.41	6.00e-124	438.00
IUUC-Apl-003505	Anas platyrhynchos	73.92	0.00e+00	1170.00
IUUC-Aca-004339	Anolis carolinensis	71.81	0.00e+00	1253.00
IUUC-Aly-005913	Arabidopsis lyrata	36.26	5.00e-153	535.00
IUUC-Ath-006767	Arabidopsis thaliana	36.34	8.00e-156	544.00
IUUC-Ago-007763	Ashbya gossypii	31.28	2.00e-118	420.00
IUUC-Acl-008275	Aspergillus clavatus	32.96	1.00e-90	327.00
IUUC-Afl-008457	Aspergillus flavus	33.67	8.00e-94	338.00
IUUC-Afu-008914	Aspergillus fumigatus	33.99	4.00e-104	372.00
IUUC-Ani-009225	Aspergillus nidulans	32.53	7.00e-104	371.00
IUUC-Aor-010046	Aspergillus oryzae	32.20	6.00e-118	418.00
IUUC-Ate-010337	Aspergillus terreus	33.16	5.00e-118	419.00
IUUC-Ame-010963	Astyanax mexicanus	66.74	0.00e+00	1158.00
IUUC-Bgr-011973	Blumeria graminis	31.47	5.00e-113	402.00
IUUC-Bta-012462	Bos taurus	91.06	0.00e+00	1559.00
IUUC-Bci-013940	Botrytis cinerea	31.59	5.00e-115	409.00
IUUC-Bdi-014725	Brachypodium distachyon	35.95	3.00e-149	522.00
IUUC-Bol-016534	Brassica oleracea	35.73	2.00e-149	523.00
IUUC-Bra-016781	Brassica rapa	35.17	1.00e-147	517.00
IUUC-Cel-018581	Caenorhabditis elegans	28.28	7.00e-87	315.00
IUUC-Cja-019675	Callithrix jacchus	92.98	0.00e+00	1620.00
IUUC-Cfa-020118	Canis familiaris	89.71	0.00e+00	1540.00
IUUC-Cre-022566	Chlamydomonas reinhardtii	29.04	4.00e-30	125.00
IUUC-Csa-023547	Chlorocebus sabaeus	93.34	0.00e+00	1595.00
IUUC-Cho-024518	Choloepus hoffmanni	78.71	0.00e+00	1264.00
IUUC-Cin-025339	Ciona intestinalis	46.42	0.00e+00	765.00
IUUC-Cgl-026476	Colletotrichum gloeosporioides	30.68	3.00e-114	406.00
IUUC-Cne-026859	Cryptococcus neoformans	34.90	2.00e-141	496.00
IUUC-Cme-027173	Cyanidioschyzon merolae	28.69	6.00e-83	302.00
IUUC-Dre-027733	Danio rerio	64.52	0.00e+00	1144.00
IUUC-Dno-029439	Dasypus novemcinctus	91.68	0.00e+00	1566.00
IUUC-Dor-030329	Dipodomys ordii	79.24	0.00e+00	1316.00
IUUC-Dse-031511	Dothistroma septosporum	30.24	3.00e-105	376.00
IUUC-Dme-031694	Drosophila melanogaster	39.91	0.00e+00	677.00
IUUC-Ete-032930	Echinops telfairi	78.07	0.00e+00	1342.00
IUUC-Eca-033302	Equus caballus	92.20	0.00e+00	1590.00
IUUC-Eeu-034516	Erinaceus europaeus	91.00	0.00e+00	1612.00
IUUC-Fca-036064	Felis catus	91.91	0.00e+00	1567.00
IUUC-Fal-037024	Ficedula albicollis	71.53	0.00e+00	1243.00
IUUC-Fox-037787	Fusarium oxysporum	29.41	1.00e-96	348.00
IUUC-Fso-038378	Fusarium solani	30.11	1.00e-99	357.00
IUUC-Gmo-039637	Gadus morhua	51.81	9.00e-153	533.00
IUUC-Ggr-040108	Gaeumannomyces graminis	29.85	5.00e-106	379.00
IUUC-Gga-040982	Gallus gallus	72.89	0.00e+00	1281.00
IUUC-Gac-041565	Gasterosteus aculeatus	56.25	0.00e+00	933.00
IUUC-Gma-043185	Glycine max	35.14	5.00e-155	541.00
IUUC-Ggo-045463	Gorilla gorilla	93.01	0.00e+00	1622.00
IUUC-Hsa-045675	Homo sapiens	92.89	0.00e+00	1620.00
IUUC-Hvu-047352	Hordeum vulgare	35.69	6.00e-132	464.00
IUUC-Itr-048088	Ictidomys tridecemlineatus	92.09	0.00e+00	1628.00
IUUC-Kpa-049164	Komagataella pastoris	33.37	2.00e-113	403.00
IUUC-Lch-050476	Latimeria chalumnae	68.44	0.00e+00	1213.00
IUUC-Lpe-051556	Leersia perrieri	28.86	7.00e-93	335.00
IUUC-Loc-052820	Lepisosteus oculatus	67.08	0.00e+00	1181.00
IUUC-Lma-052961	Leptosphaeria maculans	33.13	1.00e-108	388.00
IUUC-Laf-054006	Loxodonta africana	88.83	0.00e+00	1540.00
IUUC-Mcc-055037	Macaca mulatta	93.12	0.00e+00	1624.00
IUUC-Mor-057280	Magnaporthe oryzae	30.96	1.00e-108	387.00
IUUC-Mpo-057408	Magnaporthe poae	29.71	1.00e-102	368.00
IUUC-Mtr-058473	Medicago truncatula	34.03	2.00e-152	533.00
IUUC-Mla-058892	Melampsora laricipopulina	34.37	8.00e-120	424.00
IUUC-Mga-059598	Meleagris gallopavo	61.75	0.00e+00	986.00
IUUC-Mvi-060334	Microbotryum violaceum	35.49	7.00e-120	425.00
IUUC-Mmr-061239	Microcebus murinus	91.51	0.00e+00	1573.00
IUUC-Mdo-062471	Monodelphis domestica	80.07	0.00e+00	1357.00
IUUC-Mmu-063872	Mus musculus	88.69	0.00e+00	1597.00
IUUC-Mac-064631	Musa acuminata	34.31	2.00e-132	466.00
IUUC-Mpu-066039	Mustela putorius furo	92.41	0.00e+00	1611.00
IUUC-Mlu-067485	Myotis lucifugus	91.75	0.00e+00	1589.00
IUUC-Nfi-068319	Neosartorya fischeri	30.44	8.00e-103	368.00
IUUC-Ncr-068725	Neurospora crassa	30.02	4.00e-105	376.00
IUUC-Nle-069050	Nomascus leucogenys	93.23	0.00e+00	1628.00
IUUC-Opr-070437	Ochotona princeps	78.72	2.00e-137	483.00
IUUC-Ont-071574	Oreochromis niloticus	57.80	0.00e+00	998.00
IUUC-Oan-072826	Ornithorhynchus anatinus	74.83	0.00e+00	1290.00
IUUC-Ocu-073995	Oryctolagus cuniculus	92.03	0.00e+00	1551.00
IUUC-Oba-075407	Oryza barthii	32.48	8.00e-118	417.00
IUUC-Obr-076451	Oryza brachyantha	36.38	8.00e-154	537.00
IUUC-Ogl-077535	Oryza glaberrima	35.62	9.00e-148	517.00
IUUC-Ogu-077995	Oryza glumaepatula	32.03	7.00e-117	414.00
IUUC-Oin-079431	Oryza indica	35.87	5.00e-150	525.00
IUUC-Olo-080495	Oryza longistaminata	31.89	6.00e-115	408.00
IUUC-Oni-082336	Oryza nivara	34.51	7.00e-138	484.00
IUUC-Opu-084028	Oryza punctata	33.07	1.00e-125	444.00
IUUC-Oru-084500	Oryza rufipogon	32.17	3.00e-115	409.00
IUUC-Osa-086242	Oryza sativa	35.93	2.00e-149	523.00
IUUC-Ola-086612	Oryzias latipes	56.26	0.00e+00	777.00
IUUC-Olu-087703	Ostreococcus lucimarinus	30.38	7.00e-104	372.00
IUUC-Oga-088572	Otolemur garnettii	91.17	0.00e+00	1576.00
IUUC-Oar-090363	Ovis aries	90.37	0.00e+00	1588.00
IUUC-Ptr-090477	Pan troglodytes	92.55	0.00e+00	1602.00
IUUC-Pan-092914	Papio anubis	93.44	0.00e+00	1625.00
IUUC-Psi-093019	Pelodiscus sinensis	72.63	0.00e+00	1259.00
IUUC-Pma-094303	Petromyzon marinus	50.90	0.00e+00	768.00
IUUC-Pno-094938	Phaeosphaeria nodorum	32.27	3.00e-100	360.00
IUUC-Ppa-095720	Physcomitrella patens	35.19	6.00e-146	511.00
IUUC-Pfo-097034	Poecilia formosa	56.29	0.00e+00	949.00
IUUC-Pab-097669	Pongo abelii	92.98	0.00e+00	1620.00
IUUC-Pop-098835	Populus trichocarpa	35.24	5.00e-149	521.00
IUUC-Pca-101097	Procavia capensis	85.29	5.00e-176	611.00
IUUC-Ppe-101430	Prunus persica	34.77	9.00e-154	537.00
IUUC-Pva-103152	Pteropus vampyrus	92.32	0.00e+00	1623.00
IUUC-Pgr-103517	Puccinia graminis	30.98	2.00e-125	443.00
IUUC-Ptt-103697	Puccinia triticina	32.51	3.00e-101	363.00
IUUC-Pte-104121	Pyrenophora teres	31.43	5.00e-107	382.00
IUUC-Pyt-104672	Pyrenophora triticirepentis	31.72	1.00e-108	387.00
IUUC-Rno-105435	Rattus norvegicus	88.99	0.00e+00	1563.00
IUUC-Sce-106202	Saccharomyces cerevisiae	31.95	1.00e-111	397.00
IUUC-Sha-107272	Sarcophilus harrisii	80.32	0.00e+00	1302.00
IUUC-Sja-107744	Schizosaccharomyces japonicus	36.47	2.00e-154	539.00
IUUC-Spo-108256	Schizosaccharomyces pombe	36.96	6.00e-151	528.00
IUUC-Ssl-108618	Sclerotinia sclerotiorum	31.33	1.00e-113	404.00
IUUC-Smo-108762	Selaginella moellendorffii	36.37	2.00e-153	536.00
IUUC-Sit-110051	Setaria italica	36.11	1.00e-149	523.00
IUUC-Sly-111181	Solanum lycopersicum	35.12	1.00e-152	533.00
IUUC-Stu-112018	Solanum tuberosum	34.69	3.00e-151	529.00
IUUC-Sar-113348	Sorex araneus	87.68	0.00e+00	1086.00
IUUC-Sbi-114282	Sorghum bicolor	36.18	2.00e-150	526.00
IUUC-Sre-114946	Sporisorium reilianum	31.49	2.00e-93	337.00
IUUC-Ssc-115287	Sus scrofa	92.07	0.00e+00	1602.00
IUUC-Tgu-117138	Taeniopygia guttata	68.25	0.00e+00	1057.00
IUUC-Tru-118232	Takifugu rubripes	57.63	0.00e+00	971.00
IUUC-Tsy-119502	Tarsius syrichta	79.10	0.00e+00	1300.00
IUUC-Tni-120378	Tetraodon nigroviridis	56.87	0.00e+00	953.00
IUUC-Tca-121506	Theobroma cacao	34.52	7.00e-144	504.00
IUUC-Tre-122166	Trichoderma reesei	29.87	2.00e-106	380.00
IUUC-Tvi-122385	Trichoderma virens	29.89	8.00e-107	381.00
IUUC-Tae-122836	Triticum aestivum	35.64	1.00e-150	526.00
IUUC-Tur-126490	Triticum urartu	32.12	1.00e-114	407.00
IUUC-Tme-127157	Tuber melanosporum	33.07	8.00e-113	401.00
IUUC-Tbe-127981	Tupaia belangeri	83.85	0.00e+00	1352.00
IUUC-Ttr-128886	Tursiops truncatus	90.22	0.00e+00	1556.00
IUUC-Uma-129439	Ustilago maydis	32.39	1.00e-100	361.00
IUUC-Vda-129760	Verticillium dahliae	29.86	3.00e-103	370.00
IUUC-Vpa-130456	Vicugna pacos	91.40	0.00e+00	1593.00
IUUC-Vvi-131086	Vitis vinifera	34.53	9.00e-147	514.00
IUUC-Xtr-131829	Xenopus tropicalis	68.83	0.00e+00	1198.00
IUUC-Xma-133588	Xiphophorus maculatus	56.29	0.00e+00	934.00
IUUC-Yli-134328	Yarrowia lipolytica	30.90	2.00e-111	397.00
IUUC-Zma-135808	Zea mays	36.15	3.00e-150	526.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence