iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055338

UUCD1 version

UUC-MaM-01002

Ensembl Protein ID

ENSMMUP00000027665.3

UniProt Accession

F7HGB1; I2CW74; F7HGB1_MACMU

Genbank Protein ID

AFJ71209.1

Protein Name

Ubiquitin-conjugating enzyme E2 C isoform 1

Genbank Nucleotide ID

JSUE03002875

Gene Name

UBE2C; LOC714349

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000031435.2	ENSMMUT00000029564.3	ENSMMUP00000027665.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.40e-45	153.4	34	166

Active Site

Position(s)	Description	Evidence
114	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++el++l+ +  +gisa p+++ +l++w  +i G ++t+Ye+  +kl++efp+ YP+++P+vkflt+++hPnv+++G++Cl+ilk  
   Q: 34   RLQQELMTLMMSGDKGISAFPESD-NLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILK-- 119
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           +kWs+ ++v+++llsiqsll epn++spln++aael+k+   ++kk +
   Q: 120  DKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPT-AFKKYL 166
           ***********************************997655.488765 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MASQNRDPAA TSVTAARKGA EPSGGAARGP VGKRLQQELM TLMMSGDKGI SAFPESDNLF 60
KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCCC AAAACCGCGA CCCGGCAGCC ACTAGCGTCA CCGCCGCCCG TAAAGGAGCC 60
GAGCCGAGCG GGGGCGCTGC CCGGGGTCCC GTGGGCAAAA GGCTACAGCA GGAGCTGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

KEGG

mcc:709380; mcc:714349

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001924	Ailuropoda melanoleuca	95.58	6.00e-95	339.00
IUUC-Atr-002885	Amborella trichopoda	61.78	4.00e-54	203.00
IUUC-Aly-006086	Arabidopsis lyrata	59.39	8.00e-54	202.00
IUUC-Ath-006897	Arabidopsis thaliana	58.97	4.00e-52	197.00
IUUC-Acl-008223	Aspergillus clavatus	66.93	2.00e-39	154.00
IUUC-Afl-008675	Aspergillus flavus	54.82	8.00e-39	152.00
IUUC-Afu-008997	Aspergillus fumigatus	66.14	3.00e-38	151.00
IUUC-Ani-009470	Aspergillus nidulans	56.02	3.00e-39	154.00
IUUC-Ang-009648	Aspergillus niger	59.46	5.00e-39	153.00
IUUC-Aor-009977	Aspergillus oryzae	58.02	9.00e-32	129.00
IUUC-Ate-010318	Aspergillus terreus	51.70	1.00e-38	152.00
IUUC-Ame-011302	Astyanax mexicanus	77.65	4.00e-76	276.00
IUUC-Bta-013101	Bos taurus	97.21	6.00e-100	355.00
IUUC-Bci-013787	Botrytis cinerea	56.71	1.00e-44	172.00
IUUC-Bdi-014144	Brachypodium distachyon	69.29	3.00e-57	214.00
IUUC-Bol-015613	Brassica oleracea	58.54	2.00e-53	201.00
IUUC-Bra-017562	Brassica rapa	58.54	2.00e-53	201.00
IUUC-Cfa-020588	Canis familiaris	97.77	3.00e-97	347.00
IUUC-Cpo-021384	Cavia porcellus	97.21	2.00e-100	357.00
IUUC-Csa-023437	Chlorocebus sabaeus	100.00	1.00e-105	375.00
IUUC-Cho-024330	Choloepus hoffmanni	99.15	5.00e-68	248.00
IUUC-Cin-025365	Ciona intestinalis	56.88	2.00e-32	130.00
IUUC-Csv-025933	Ciona savignyi	61.49	4.00e-59	220.00
IUUC-Cgl-026494	Colletotrichum gloeosporioides	57.74	7.00e-45	172.00
IUUC-Cme-027266	Cyanidioschyzon merolae	50.97	2.00e-37	148.00
IUUC-Dre-027375	Danio rerio	77.65	2.00e-75	274.00
IUUC-Dno-029921	Dasypus novemcinctus	94.97	3.00e-94	337.00
IUUC-Dor-030209	Dipodomys ordii	93.85	1.00e-95	341.00
IUUC-Dse-031516	Dothistroma septosporum	54.67	4.00e-38	150.00
IUUC-Dme-031942	Drosophila melanogaster	67.13	8.00e-56	209.00
IUUC-Ete-032827	Echinops telfairi	84.69	4.00e-41	158.00
IUUC-Eca-034073	Equus caballus	98.32	1.00e-97	348.00
IUUC-Eeu-034854	Erinaceus europaeus	75.98	2.00e-68	251.00
IUUC-Fca-035666	Felis catus	98.32	1.00e-97	348.00
IUUC-Fal-037652	Ficedula albicollis	87.62	7.00e-54	201.00
IUUC-Fox-037793	Fusarium oxysporum	57.32	8.00e-44	169.00
IUUC-Fso-038151	Fusarium solani	58.02	3.00e-45	174.00
IUUC-Gmo-038894	Gadus morhua	78.48	3.00e-61	227.00
IUUC-Ggr-039730	Gaeumannomyces graminis	61.03	2.00e-35	141.00
IUUC-Gga-040537	Gallus gallus	87.50	5.00e-71	259.00
IUUC-Gac-041346	Gasterosteus aculeatus	72.16	2.00e-62	231.00
IUUC-Gma-043989	Glycine max	61.69	2.00e-54	204.00
IUUC-Ggo-045594	Gorilla gorilla	97.79	3.00e-103	367.00
IUUC-Hsa-046216	Homo sapiens	98.88	1.00e-104	371.00
IUUC-Hvu-047797	Hordeum vulgare	70.15	2.00e-54	204.00
IUUC-Itr-048402	Ictidomys tridecemlineatus	98.32	1.00e-97	348.00
IUUC-Lch-049761	Latimeria chalumnae	70.39	4.00e-72	263.00
IUUC-Lpe-051089	Leersia perrieri	63.46	1.00e-55	209.00
IUUC-Loc-052297	Lepisosteus oculatus	76.47	3.00e-73	268.00
IUUC-Lma-053214	Leptosphaeria maculans	50.97	3.00e-43	167.00
IUUC-Laf-054468	Loxodonta africana	96.13	1.00e-101	361.00
IUUC-Meu-056147	Macropus eugenii	92.18	5.00e-94	336.00
IUUC-Mtr-057687	Medicago truncatula	59.64	4.00e-48	183.00
IUUC-Mla-058880	Melampsora laricipopulina	64.29	2.00e-50	191.00
IUUC-Mmr-060747	Microcebus murinus	98.14	2.00e-86	310.00
IUUC-Mdo-062343	Monodelphis domestica	93.89	4.00e-95	339.00
IUUC-Mmu-063563	Mus musculus	95.53	5.00e-98	349.00
IUUC-Mac-064823	Musa acuminata	63.83	3.00e-53	200.00
IUUC-Mpu-065746	Mustela putorius furo	96.69	9.00e-96	342.00
IUUC-Mlu-067388	Myotis lucifugus	95.58	2.00e-94	337.00
IUUC-Nfi-068577	Neosartorya fischeri	63.04	6.00e-39	153.00
IUUC-Ncr-068803	Neurospora crassa	57.59	8.00e-39	152.00
IUUC-Opr-070902	Ochotona princeps	93.33	1.00e-94	338.00
IUUC-Ont-071672	Oreochromis niloticus	70.29	7.00e-65	239.00
IUUC-Ocu-074566	Oryctolagus cuniculus	92.78	2.00e-91	327.00
IUUC-Oba-075538	Oryza barthii	67.94	5.00e-52	196.00
IUUC-Ogu-078467	Oryza glumaepatula	66.44	3.00e-56	211.00
IUUC-Oin-079533	Oryza indica	67.18	2.00e-51	194.00
IUUC-Olo-080673	Oryza longistaminata	68.70	1.00e-52	197.00
IUUC-Ome-081483	Oryza meridionalis	67.86	2.00e-55	208.00
IUUC-Oni-082321	Oryza nivara	66.44	3.00e-56	211.00
IUUC-Opu-083245	Oryza punctata	66.43	3.00e-54	204.00
IUUC-Oru-084641	Oryza rufipogon	63.64	2.00e-54	205.00
IUUC-Osa-085992	Oryza sativa	66.44	3.00e-56	211.00
IUUC-Ola-086807	Oryzias latipes	73.03	2.00e-72	264.00
IUUC-Olu-087834	Ostreococcus lucimarinus	70.07	2.00e-55	207.00
IUUC-Oga-088699	Otolemur garnettii	95.60	6.00e-102	362.00
IUUC-Oar-089542	Ovis aries	96.69	8.00e-96	342.00
IUUC-Ptr-091069	Pan troglodytes	98.88	1.00e-104	371.00
IUUC-Pan-092533	Papio anubis	98.90	3.00e-104	370.00
IUUC-Psi-093581	Pelodiscus sinensis	68.07	5.00e-59	219.00
IUUC-Pma-094607	Petromyzon marinus	71.18	5.00e-70	256.00
IUUC-Pno-094829	Phaeosphaeria nodorum	54.73	3.00e-43	167.00
IUUC-Ppa-095861	Physcomitrella patens	67.14	6.00e-56	209.00
IUUC-Pfo-096836	Poecilia formosa	70.69	2.00e-67	247.00
IUUC-Pab-098707	Pongo abelii	98.88	1.00e-104	371.00
IUUC-Pop-099021	Populus trichocarpa	67.14	2.00e-54	204.00
IUUC-Pca-100661	Procavia capensis	97.77	2.00e-99	354.00
IUUC-Ppe-101289	Prunus persica	57.71	1.00e-54	205.00
IUUC-Pva-103235	Pteropus vampyrus	93.30	5.00e-89	319.00
IUUC-Pte-104292	Pyrenophora teres	59.40	2.00e-43	167.00
IUUC-Rno-105501	Rattus norvegicus	96.09	6.00e-99	352.00
IUUC-Sha-107205	Sarcophilus harrisii	94.33	1.00e-77	282.00
IUUC-Spo-108136	Schizosaccharomyces pombe	55.56	6.00e-51	193.00
IUUC-Ssl-108394	Sclerotinia sclerotiorum	57.23	8.00e-45	172.00
IUUC-Smo-109459	Selaginella moellendorffii	65.44	1.00e-52	199.00
IUUC-Sit-110754	Setaria italica	67.14	1.00e-55	208.00
IUUC-Sly-111137	Solanum lycopersicum	66.20	6.00e-54	202.00
IUUC-Stu-112305	Solanum tuberosum	65.97	3.00e-54	204.00
IUUC-Sbi-114299	Sorghum bicolor	64.08	5.00e-52	196.00
IUUC-Ssc-115625	Sus scrofa	97.77	1.00e-97	348.00
IUUC-Tni-120070	Tetraodon nigroviridis	72.52	2.00e-56	211.00
IUUC-Tca-121158	Theobroma cacao	60.48	2.00e-55	207.00
IUUC-Tre-121973	Trichoderma reesei	57.83	3.00e-45	174.00
IUUC-Tvi-122496	Trichoderma virens	57.49	3.00e-45	174.00
IUUC-Tae-123596	Triticum aestivum	66.44	1.00e-56	212.00
IUUC-Tur-126818	Triticum urartu	65.52	7.00e-43	165.00
IUUC-Tme-127044	Tuber melanosporum	66.42	2.00e-42	164.00
IUUC-Ttr-128548	Tursiops truncatus	76.54	1.00e-68	251.00
IUUC-Vda-129840	Verticillium dahliae	55.69	6.00e-44	169.00
IUUC-Vvi-131685	Vitis vinifera	60.84	1.00e-55	208.00
IUUC-Xtr-132953	Xenopus tropicalis	79.89	8.00e-83	298.00
IUUC-Xma-134093	Xiphophorus maculatus	70.69	2.00e-67	247.00
IUUC-Zma-135182	Zea mays	66.43	6.00e-55	206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence