iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000002459.1	ENSSHAT00000002810.1	ENSSHAP00000002779.1
ENSSHAG00000002459.1	ENSSHAT00000002811.1	ENSSHAP00000002780.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.90e-137	458.4	10	422

Active Site

Position(s)	Description	Evidence
173	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 11   eaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           e  e++   +vl+vGagg+GcEllKnLvl+G+ +i ++D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ pd n+ a+++si++
   Q: 10   ELAEAVAGGRVLVVGAGGIGCELLKNLVLSGFAHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPDANIIAYHDSIMN 98
           6789999********************************************************************************** PP
   S: 100  leeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtie 188
           ++++++Ff++f++V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv+vi kg+tecy+c+++p+qkt+P+ct+++tp+++ h+i+
   Q: 99   PDYNVEFFRQFTLVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTVIKKGVTECYECHPKPTQKTFPGCTIRNTPSEPIHCIV 187
           ***************************************************************************************** PP
   S: 189  wa.vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv. 274
           wa +lfn+l++ee++++ev++  d++++e+++++ ++e+++++++++ ++++i++k++ak+t ++ +k ++k f++di++  ++++++ 
   Q: 188  WAkYLFNQLFGEEDADQEVSP--DRADPEAAWEPAEAEARARASNEDGDIKRISTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDKLWr 274
           *********************..799*************************************************************** PP
   S: 275  ..................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaa 340
                                 n +++++   ++kd++v++++++     +++++++++++ek +g    el ++kdd+sa+d+vt+aa
   Q: 275  krkppvpldwtevqsqdnGKDANGDQQNESTLGLKDQQVLDVKSYarlfsKSIETLRVHLAEKGDGA---ELIWDKDDPSAMDFVTSAA 360
           ***********9999988778888999999*************************************...68***************** PP
   S: 341  nlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           nlr++ +++++  ++++ik++agniipaiattnav++Gl+++E +K++sgk ++++++fl+++
   Q: 361  NLRMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQ 422
           ***********.***********************************************9965 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MALSRGLSRE LAEAVAGGRV LVVGAGGIGC ELLKNLVLSG FAHIDLIDLD TIDVSNLNRQ 60
FLFQKKHVGR SKAQVAKESV LQFYPDANII AYHDSIMNPD YNVEFFRQFT LVMNALDNRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTATTTAC CACTCATGGT GCTATTTTAC CACTTTATAA ATTCTAGAAA CCTCCTCCTC 60
CCCCAATCTG GGGAAGGACT GTAATACAAA GATTACTTGA ACTTTTAGGC AGAGATGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	40.48	5.00e-107	381.00
IUUC-Aml-001662	Ailuropoda melanoleuca	92.38	0.00e+00	1149.00
IUUC-Atr-002636	Amborella trichopoda	39.22	3.00e-115	409.00
IUUC-Apl-003369	Anas platyrhynchos	90.08	0.00e+00	1033.00
IUUC-Aca-004490	Anolis carolinensis	82.77	0.00e+00	920.00
IUUC-Aly-006359	Arabidopsis lyrata	42.12	2.00e-104	372.00
IUUC-Ath-007667	Arabidopsis thaliana	43.22	3.00e-108	385.00
IUUC-Ago-007844	Ashbya gossypii	36.11	7.00e-83	301.00
IUUC-Acl-008270	Aspergillus clavatus	43.52	1.00e-106	380.00
IUUC-Afl-008674	Aspergillus flavus	43.62	2.00e-112	399.00
IUUC-Afu-008883	Aspergillus fumigatus	42.86	6.00e-107	381.00
IUUC-Ani-009500	Aspergillus nidulans	44.87	3.00e-113	402.00
IUUC-Ang-009535	Aspergillus niger	42.63	3.00e-111	395.00
IUUC-Aor-010223	Aspergillus oryzae	43.43	7.00e-113	400.00
IUUC-Ate-010282	Aspergillus terreus	44.92	2.00e-89	322.00
IUUC-Ame-011736	Astyanax mexicanus	77.88	0.00e+00	966.00
IUUC-Bgr-012166	Blumeria graminis	41.60	1.00e-99	357.00
IUUC-Bta-012589	Bos taurus	92.36	0.00e+00	1155.00
IUUC-Bci-013802	Botrytis cinerea	42.64	1.00e-101	363.00
IUUC-Bdi-014697	Brachypodium distachyon	40.84	6.00e-110	391.00
IUUC-Bol-016315	Brassica oleracea	39.27	3.00e-110	392.00
IUUC-Bra-017009	Brassica rapa	40.24	4.00e-111	395.00
IUUC-Cel-018708	Caenorhabditis elegans	45.93	3.00e-132	464.00
IUUC-Cja-019120	Callithrix jacchus	93.15	0.00e+00	1152.00
IUUC-Cfa-021061	Canis familiaris	92.83	0.00e+00	1158.00
IUUC-Cpo-021842	Cavia porcellus	92.21	0.00e+00	1142.00
IUUC-Csa-024104	Chlorocebus sabaeus	93.16	0.00e+00	1120.00
IUUC-Cho-024332	Choloepus hoffmanni	82.46	0.00e+00	838.00
IUUC-Cin-025363	Ciona intestinalis	60.66	0.00e+00	665.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	42.94	2.00e-99	356.00
IUUC-Cne-026888	Cryptococcus neoformans	44.31	6.00e-73	268.00
IUUC-Cme-027315	Cyanidioschyzon merolae	46.50	1.00e-51	197.00
IUUC-Dre-028420	Danio rerio	75.36	0.00e+00	923.00
IUUC-Dno-030041	Dasypus novemcinctus	92.38	0.00e+00	1149.00
IUUC-Dor-031039	Dipodomys ordii	76.57	8.00e-173	600.00
IUUC-Dse-031504	Dothistroma septosporum	35.97	2.00e-95	343.00
IUUC-Dme-031771	Drosophila melanogaster	50.50	5.00e-149	521.00
IUUC-Ete-033037	Echinops telfairi	87.07	0.00e+00	1033.00
IUUC-Eca-033774	Equus caballus	92.95	0.00e+00	1118.00
IUUC-Eeu-035074	Erinaceus europaeus	92.02	0.00e+00	893.00
IUUC-Fca-036508	Felis catus	93.29	0.00e+00	1121.00
IUUC-Fal-036813	Ficedula albicollis	88.10	0.00e+00	1028.00
IUUC-Fox-038056	Fusarium oxysporum	42.46	5.00e-105	375.00
IUUC-Fso-038223	Fusarium solani	42.93	7.00e-105	374.00
IUUC-Gmo-038526	Gadus morhua	75.59	0.00e+00	875.00
IUUC-Ggr-039767	Gaeumannomyces graminis	42.99	8.00e-100	357.00
IUUC-Gga-040981	Gallus gallus	88.46	0.00e+00	1055.00
IUUC-Gac-041437	Gasterosteus aculeatus	75.72	0.00e+00	899.00
IUUC-Gma-044072	Glycine max	37.94	6.00e-115	407.00
IUUC-Ggo-045358	Gorilla gorilla	89.81	0.00e+00	1064.00
IUUC-Hsa-046068	Homo sapiens	93.30	0.00e+00	1124.00
IUUC-Hvu-047646	Hordeum vulgare	37.32	6.00e-108	384.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	92.69	0.00e+00	1149.00
IUUC-Lch-049565	Latimeria chalumnae	82.40	0.00e+00	1023.00
IUUC-Lpe-050884	Leersia perrieri	41.50	2.00e-111	395.00
IUUC-Loc-052493	Lepisosteus oculatus	81.77	0.00e+00	999.00
IUUC-Lma-053117	Leptosphaeria maculans	44.96	8.00e-104	370.00
IUUC-Laf-054518	Loxodonta africana	89.89	0.00e+00	1134.00
IUUC-Mcc-055334	Macaca mulatta	93.15	0.00e+00	1122.00
IUUC-Mor-057137	Magnaporthe oryzae	44.29	1.00e-95	343.00
IUUC-Mpo-057449	Magnaporthe poae	41.61	2.00e-102	366.00
IUUC-Mtr-058045	Medicago truncatula	39.48	1.00e-118	420.00
IUUC-Mla-058864	Melampsora laricipopulina	46.35	1.00e-97	350.00
IUUC-Mga-059422	Meleagris gallopavo	84.04	0.00e+00	939.00
IUUC-Mvi-060536	Microbotryum violaceum	41.53	2.00e-88	319.00
IUUC-Mmr-061161	Microcebus murinus	91.13	0.00e+00	1144.00
IUUC-Mdo-061802	Monodelphis domestica	96.88	0.00e+00	1182.00
IUUC-Mmu-064357	Mus musculus	90.95	0.00e+00	1160.00
IUUC-Mac-065475	Musa acuminata	39.39	2.00e-110	392.00
IUUC-Mpu-066895	Mustela putorius furo	92.99	0.00e+00	1158.00
IUUC-Mlu-067862	Myotis lucifugus	92.85	0.00e+00	1157.00
IUUC-Nfi-068385	Neosartorya fischeri	44.49	7.00e-109	387.00
IUUC-Ncr-068885	Neurospora crassa	41.56	1.00e-106	380.00
IUUC-Nle-069524	Nomascus leucogenys	92.68	0.00e+00	1108.00
IUUC-Opr-071038	Ochotona princeps	92.83	0.00e+00	1194.00
IUUC-Ont-071719	Oreochromis niloticus	76.50	0.00e+00	959.00
IUUC-Oan-072877	Ornithorhynchus anatinus	91.43	0.00e+00	994.00
IUUC-Ocu-074080	Oryctolagus cuniculus	92.52	0.00e+00	1145.00
IUUC-Oba-075936	Oryza barthii	40.22	5.00e-110	391.00
IUUC-Obr-076841	Oryza brachyantha	41.03	5.00e-112	398.00
IUUC-Ogl-077686	Oryza glaberrima	40.25	1.00e-111	396.00
IUUC-Ogu-078597	Oryza glumaepatula	39.15	7.00e-107	381.00
IUUC-Oin-079791	Oryza indica	40.22	5.00e-110	391.00
IUUC-Olo-081009	Oryza longistaminata	40.22	5.00e-110	391.00
IUUC-Ome-081327	Oryza meridionalis	37.39	1.00e-104	373.00
IUUC-Oni-082334	Oryza nivara	39.36	2.00e-107	382.00
IUUC-Opu-083447	Oryza punctata	40.91	4.00e-112	398.00
IUUC-Oru-084977	Oryza rufipogon	40.22	5.00e-110	391.00
IUUC-Osa-086160	Oryza sativa	44.36	3.00e-96	345.00
IUUC-Ola-087415	Oryzias latipes	75.99	0.00e+00	949.00
IUUC-Olu-087850	Ostreococcus lucimarinus	40.44	1.00e-98	353.00
IUUC-Oga-088434	Otolemur garnettii	92.37	0.00e+00	1149.00
IUUC-Oar-089872	Ovis aries	92.28	0.00e+00	1105.00
IUUC-Ptr-091212	Pan troglodytes	93.30	0.00e+00	1124.00
IUUC-Pan-092708	Papio anubis	96.14	2.00e-128	452.00
IUUC-Psi-093703	Pelodiscus sinensis	91.60	0.00e+00	1062.00
IUUC-Pno-094953	Phaeosphaeria nodorum	47.31	5.00e-106	378.00
IUUC-Ppa-095963	Physcomitrella patens	43.25	1.00e-110	393.00
IUUC-Pfo-097515	Poecilia formosa	75.55	0.00e+00	916.00
IUUC-Pab-097951	Pongo abelii	92.86	0.00e+00	977.00
IUUC-Pop-099703	Populus trichocarpa	36.72	3.00e-96	345.00
IUUC-Pca-100426	Procavia capensis	89.72	0.00e+00	1120.00
IUUC-Ppe-101152	Prunus persica	39.73	1.00e-112	400.00
IUUC-Pva-102792	Pteropus vampyrus	89.02	0.00e+00	1073.00
IUUC-Pgr-103592	Puccinia graminis	39.15	4.00e-101	362.00
IUUC-Ptt-103805	Puccinia triticina	41.92	1.00e-87	317.00
IUUC-Pte-104215	Pyrenophora teres	45.44	7.00e-112	397.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	46.64	6.00e-111	394.00
IUUC-Rno-106117	Rattus norvegicus	90.64	0.00e+00	1159.00
IUUC-Sce-106177	Saccharomyces cerevisiae	37.02	1.00e-73	270.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	43.64	2.00e-94	340.00
IUUC-Spo-108020	Schizosaccharomyces pombe	45.34	2.00e-95	343.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	43.18	5.00e-102	365.00
IUUC-Smo-109264	Selaginella moellendorffii	40.45	2.00e-106	379.00
IUUC-Sit-110581	Setaria italica	41.65	8.00e-111	394.00
IUUC-Sly-111870	Solanum lycopersicum	39.93	3.00e-114	405.00
IUUC-Stu-112283	Solanum tuberosum	39.57	7.00e-112	397.00
IUUC-Sar-113432	Sorex araneus	67.95	4.00e-146	511.00
IUUC-Sbi-114075	Sorghum bicolor	39.42	2.00e-110	392.00
IUUC-Sre-114926	Sporisorium reilianum	39.82	6.00e-104	371.00
IUUC-Ssc-116281	Sus scrofa	96.70	5.00e-112	396.00
IUUC-Tgu-117247	Taeniopygia guttata	86.58	0.00e+00	1025.00
IUUC-Tru-118075	Takifugu rubripes	72.35	0.00e+00	880.00
IUUC-Tsy-119398	Tarsius syrichta	77.26	0.00e+00	876.00
IUUC-Tni-120771	Tetraodon nigroviridis	67.08	0.00e+00	796.00
IUUC-Tca-121651	Theobroma cacao	39.31	1.00e-113	403.00
IUUC-Tre-122224	Trichoderma reesei	43.73	6.00e-96	344.00
IUUC-Tvi-122634	Trichoderma virens	43.05	7.00e-97	348.00
IUUC-Tae-125665	Triticum aestivum	40.41	3.00e-105	375.00
IUUC-Tur-126417	Triticum urartu	37.70	7.00e-106	377.00
IUUC-Tme-127016	Tuber melanosporum	45.03	5.00e-98	351.00
IUUC-Tbe-127678	Tupaia belangeri	90.14	2.00e-156	545.00
IUUC-Ttr-128598	Tursiops truncatus	88.63	0.00e+00	1095.00
IUUC-Uma-129612	Ustilago maydis	43.05	1.00e-95	343.00
IUUC-Vda-129811	Verticillium dahliae	44.79	4.00e-101	362.00
IUUC-Vpa-130732	Vicugna pacos	78.82	0.00e+00	939.00
IUUC-Vvi-130832	Vitis vinifera	42.54	8.00e-109	387.00
IUUC-Xtr-132823	Xenopus tropicalis	76.96	0.00e+00	907.00
IUUC-Xma-133552	Xiphophorus maculatus	76.03	0.00e+00	915.00
IUUC-Yli-134666	Yarrowia lipolytica	38.85	6.00e-77	281.00
IUUC-Zma-135547	Zea mays	38.65	5.00e-109	388.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence