iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068712

Ensembl Protein ID

EAA28717

UniProt Accession

Q7S086; Q7S086_NEUCR

Genbank Protein ID

EAA28717.2

Protein Name

Ubiquitin conjugating enzyme Ubc8

Genbank Nucleotide ID

CM002241

Gene Name

NCU10046

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU10046	EAA28717	EAA28717

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.60e-32	109.4	4	117

Active Site

Position(s)	Description	Evidence
61	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 26   dltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsvesvl.lsiqsllaepnpesplneeaae 124
            ++e+ v + Gp++tp+egg++k+++e+p++YP+k+P++ f+++ifhPn++e  G+vCl++++  ++Wsp+ ++ +++ + + +ll+ pnp +pln eaa 
   Q: 4    AVQEFYVRFKGPAETPFEGGIWKVRVELPDQYPYKSPSIGFVNRIFHPNIDELsGSVCLDVIN--QTWSPMFDMINIFeVFLPQLLRYPNPTDPLNGEAAA 102
           589999**********************************************99********9..*************889******************** PP
   S: 125  llkknreeykkkvre 139
           +l +++++y++kv+e
   Q: 103  MLLREPKTYENKVKE 117
           ************985 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MENAVQEFYV RFKGPAETPF EGGIWKVRVE LPDQYPYKSP SIGFVNRIFH PNIDELSGSV 60
CLDVINQTWS PMFDMINIFE VFLPQLLRYP NPTDPLNGEA AAMLLREPKT YENKVKEYVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTACTTTG GTGAACGATA ATAGTATGGA TACACCCTTT CCAACTCCCT GTAGGAAACA 60
TTCAACTTCC GGTTTCGGAG CGCTAACATG GAGAATGCAG TGTAAGATGC GACAACTAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ncr:NCU10046

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000745	Aegilops tauschii	70.31	2.00e-55	206.00
IUUC-Aml-001260	Ailuropoda melanoleuca	66.15	3.00e-46	176.00
IUUC-Atr-002681	Amborella trichopoda	71.54	7.00e-56	207.00
IUUC-Apl-003547	Anas platyrhynchos	71.15	2.00e-45	172.00
IUUC-Aca-005224	Anolis carolinensis	66.15	9.00e-46	174.00
IUUC-Aly-005836	Arabidopsis lyrata	67.72	4.00e-55	205.00
IUUC-Ath-007534	Arabidopsis thaliana	66.93	9.00e-55	204.00
IUUC-Ago-007727	Ashbya gossypii	59.52	4.00e-47	179.00
IUUC-Acl-008119	Aspergillus clavatus	88.06	1.00e-68	250.00
IUUC-Afl-008412	Aspergillus flavus	86.78	1.00e-60	223.00
IUUC-Afu-008925	Aspergillus fumigatus	86.23	2.00e-69	253.00
IUUC-Ani-009294	Aspergillus nidulans	81.53	3.00e-74	268.00
IUUC-Ang-009805	Aspergillus niger	88.06	2.00e-68	249.00
IUUC-Aor-010201	Aspergillus oryzae	75.48	3.00e-65	239.00
IUUC-Ate-010441	Aspergillus terreus	87.70	2.00e-61	226.00
IUUC-Ame-010807	Astyanax mexicanus	64.94	7.00e-31	124.00
IUUC-Bta-012802	Bos taurus	66.15	3.00e-46	176.00
IUUC-Bdi-014415	Brachypodium distachyon	71.43	1.00e-56	210.00
IUUC-Bol-016385	Brassica oleracea	59.63	8.00e-55	204.00
IUUC-Bra-016989	Brassica rapa	60.00	4.00e-54	202.00
IUUC-Cel-018412	Caenorhabditis elegans	58.14	3.00e-48	182.00
IUUC-Cja-019571	Callithrix jacchus	48.15	3.00e-34	136.00
IUUC-Cfa-020811	Canis familiaris	66.15	3.00e-46	176.00
IUUC-Cpo-021889	Cavia porcellus	66.15	3.00e-46	176.00
IUUC-Cre-022956	Chlamydomonas reinhardtii	60.00	3.00e-57	212.00
IUUC-Csa-023289	Chlorocebus sabaeus	66.15	3.00e-46	176.00
IUUC-Cho-024517	Choloepus hoffmanni	66.22	1.00e-20	90.50
IUUC-Cin-025571	Ciona intestinalis	47.41	5.00e-32	128.00
IUUC-Cgl-026627	Colletotrichum gloeosporioides	86.79	7.00e-81	290.00
IUUC-Cne-027006	Cryptococcus neoformans	73.33	6.00e-56	208.00
IUUC-Cme-027171	Cyanidioschyzon merolae	69.60	4.00e-55	205.00
IUUC-Dre-027450	Danio rerio	67.19	3.00e-46	175.00
IUUC-Dno-029838	Dasypus novemcinctus	66.15	3.00e-46	176.00
IUUC-Dor-031119	Dipodomys ordii	66.15	3.00e-46	176.00
IUUC-Dse-031243	Dothistroma septosporum	81.65	5.00e-76	274.00
IUUC-Dme-031807	Drosophila melanogaster	66.41	8.00e-52	194.00
IUUC-Ete-032437	Echinops telfairi	69.01	5.00e-30	121.00
IUUC-Eca-034123	Equus caballus	67.19	2.00e-46	176.00
IUUC-Fca-035502	Felis catus	66.15	3.00e-46	176.00
IUUC-Fal-037054	Ficedula albicollis	67.19	2.00e-46	176.00
IUUC-Fox-037912	Fusarium oxysporum	88.49	1.00e-55	206.00
IUUC-Fso-038148	Fusarium solani	86.54	1.00e-67	246.00
IUUC-Gmo-038858	Gadus morhua	65.38	7.00e-53	197.00
IUUC-Ggr-039749	Gaeumannomyces graminis	83.65	5.00e-77	278.00
IUUC-Gga-040942	Gallus gallus	66.15	3.00e-46	176.00
IUUC-Gac-042079	Gasterosteus aculeatus	65.38	3.00e-53	199.00
IUUC-Gma-044100	Glycine max	73.17	1.00e-57	214.00
IUUC-Hsa-046545	Homo sapiens	66.15	3.00e-46	176.00
IUUC-Hvu-047260	Hordeum vulgare	68.29	7.00e-54	201.00
IUUC-Itr-048474	Ictidomys tridecemlineatus	66.15	3.00e-46	176.00
IUUC-Kpa-049144	Komagataella pastoris	78.22	3.00e-48	182.00
IUUC-Lch-050589	Latimeria chalumnae	66.15	4.00e-46	175.00
IUUC-Lpe-051335	Leersia perrieri	71.43	4.00e-56	208.00
IUUC-Loc-052829	Lepisosteus oculatus	70.75	6.00e-46	174.00
IUUC-Lma-052971	Leptosphaeria maculans	73.37	5.00e-68	248.00
IUUC-Laf-053526	Loxodonta africana	66.15	2.00e-46	176.00
IUUC-Mcc-055611	Macaca mulatta	66.15	3.00e-46	176.00
IUUC-Mor-057278	Magnaporthe oryzae	85.62	2.00e-78	282.00
IUUC-Mpo-057484	Magnaporthe poae	84.72	6.00e-72	260.00
IUUC-Mtr-058579	Medicago truncatula	61.88	3.00e-58	215.00
IUUC-Mla-058926	Melampsora laricipopulina	71.34	4.00e-62	228.00
IUUC-Mga-059801	Meleagris gallopavo	66.15	3.00e-46	176.00
IUUC-Mvi-060244	Microbotryum violaceum	79.67	9.00e-61	224.00
IUUC-Mmr-061205	Microcebus murinus	66.15	3.00e-46	176.00
IUUC-Mdo-062038	Monodelphis domestica	67.44	5.00e-27	110.00
IUUC-Mmu-063974	Mus musculus	66.15	3.00e-46	176.00
IUUC-Mac-064837	Musa acuminata	71.54	1.00e-55	207.00
IUUC-Mpu-066759	Mustela putorius furo	66.15	3.00e-46	176.00
IUUC-Mlu-067674	Myotis lucifugus	66.15	2.00e-46	176.00
IUUC-Nfi-068618	Neosartorya fischeri	86.23	6.00e-69	251.00
IUUC-Nle-069926	Nomascus leucogenys	66.15	3.00e-46	176.00
IUUC-Opr-070598	Ochotona princeps	66.15	3.00e-46	176.00
IUUC-Ont-071893	Oreochromis niloticus	68.00	2.00e-53	199.00
IUUC-Oan-073273	Ornithorhynchus anatinus	66.15	2.00e-46	176.00
IUUC-Ocu-074357	Oryctolagus cuniculus	70.75	8.00e-46	174.00
IUUC-Oba-075055	Oryza barthii	71.43	4.00e-56	208.00
IUUC-Obr-076538	Oryza brachyantha	69.53	7.00e-56	207.00
IUUC-Ogl-077784	Oryza glaberrima	71.43	4.00e-56	208.00
IUUC-Ogu-078045	Oryza glumaepatula	71.43	4.00e-56	208.00
IUUC-Oin-079163	Oryza indica	71.43	4.00e-56	208.00
IUUC-Olo-080847	Oryza longistaminata	65.12	2.00e-50	190.00
IUUC-Ome-081586	Oryza meridionalis	64.29	7.00e-54	201.00
IUUC-Oni-082913	Oryza nivara	71.43	4.00e-56	208.00
IUUC-Opu-083651	Oryza punctata	71.43	4.00e-56	208.00
IUUC-Oru-084980	Oryza rufipogon	71.43	4.00e-56	208.00
IUUC-Osa-085334	Oryza sativa	73.68	4.00e-53	197.00
IUUC-Ola-087423	Oryzias latipes	66.15	6.00e-54	201.00
IUUC-Oga-088412	Otolemur garnettii	66.15	3.00e-46	176.00
IUUC-Oar-090282	Ovis aries	66.15	3.00e-46	176.00
IUUC-Ptr-090470	Pan troglodytes	66.15	3.00e-46	176.00
IUUC-Pan-092552	Papio anubis	66.15	3.00e-46	176.00
IUUC-Psi-093516	Pelodiscus sinensis	66.15	2.00e-46	176.00
IUUC-Pno-094800	Phaeosphaeria nodorum	78.01	2.00e-62	229.00
IUUC-Ppa-095962	Physcomitrella patens	73.39	2.00e-56	209.00
IUUC-Pfo-096105	Poecilia formosa	68.00	2.00e-53	199.00
IUUC-Pab-098112	Pongo abelii	66.15	3.00e-46	176.00
IUUC-Pop-099367	Populus trichocarpa	70.73	5.00e-56	208.00
IUUC-Pca-100436	Procavia capensis	51.33	8.00e-31	124.00
IUUC-Ppe-102031	Prunus persica	70.73	2.00e-56	209.00
IUUC-Pva-102776	Pteropus vampyrus	66.15	3.00e-46	176.00
IUUC-Pgr-103325	Puccinia graminis	70.70	4.00e-62	228.00
IUUC-Ptt-104010	Puccinia triticina	68.79	2.00e-58	216.00
IUUC-Pte-104024	Pyrenophora teres	79.75	8.00e-73	264.00
IUUC-Pyt-104715	Pyrenophora triticirepentis	79.75	2.00e-72	262.00
IUUC-Rno-105699	Rattus norvegicus	65.38	6.00e-46	174.00
IUUC-Sce-106165	Saccharomyces cerevisiae	64.15	1.00e-41	160.00
IUUC-Sha-106524	Sarcophilus harrisii	66.15	2.00e-46	176.00
IUUC-Sja-107813	Schizosaccharomyces japonicus	74.80	5.00e-58	214.00
IUUC-Spo-108105	Schizosaccharomyces pombe	81.60	1.00e-61	226.00
IUUC-Ssl-108543	Sclerotinia sclerotiorum	81.38	8.00e-63	230.00
IUUC-Smo-108956	Selaginella moellendorffii	63.19	8.00e-57	211.00
IUUC-Sit-110211	Setaria italica	70.31	3.00e-56	210.00
IUUC-Sly-111361	Solanum lycopersicum	62.50	1.00e-59	220.00
IUUC-Stu-112765	Solanum tuberosum	63.12	4.00e-60	221.00
IUUC-Sar-113572	Sorex araneus	47.69	2.00e-24	102.00
IUUC-Sbi-114111	Sorghum bicolor	71.43	3.00e-56	209.00
IUUC-Sre-115027	Sporisorium reilianum	71.52	1.00e-65	240.00
IUUC-Ssc-116221	Sus scrofa	66.41	2.00e-44	169.00
IUUC-Tgu-116965	Taeniopygia guttata	66.15	3.00e-46	175.00
IUUC-Tru-117574	Takifugu rubripes	67.20	2.00e-45	173.00
IUUC-Tni-120422	Tetraodon nigroviridis	67.20	2.00e-45	173.00
IUUC-Tca-121070	Theobroma cacao	72.36	8.00e-57	210.00
IUUC-Tre-122110	Trichoderma reesei	85.99	4.00e-70	254.00
IUUC-Tvi-122592	Trichoderma virens	85.90	3.00e-68	248.00
IUUC-Tae-124413	Triticum aestivum	69.84	1.00e-55	206.00
IUUC-Tur-126414	Triticum urartu	70.31	2.00e-55	206.00
IUUC-Tme-127020	Tuber melanosporum	77.62	3.00e-53	198.00
IUUC-Tbe-128053	Tupaia belangeri	51.18	7.00e-28	114.00
IUUC-Ttr-128734	Tursiops truncatus	66.15	3.00e-46	176.00
IUUC-Uma-129334	Ustilago maydis	70.12	9.00e-66	240.00
IUUC-Vda-129953	Verticillium dahliae	84.18	2.00e-71	259.00
IUUC-Vpa-130729	Vicugna pacos	66.15	3.00e-46	175.00
IUUC-Vvi-131633	Vitis vinifera	70.73	7.00e-57	211.00
IUUC-Xtr-132368	Xenopus tropicalis	64.66	2.00e-46	176.00
IUUC-Xma-133407	Xiphophorus maculatus	68.00	2.00e-53	199.00
IUUC-Yli-134339	Yarrowia lipolytica	81.75	1.00e-63	233.00
IUUC-Zma-135728	Zea mays	72.88	8.00e-55	204.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence