iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggr-040005

Ensembl Protein ID

GGTG_08806T0

UniProt Accession

J3P5L6; J3P5L6_GAGT3

Genbank Protein ID

EJT74968.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

ADBI01000732

Gene Name

GGTG_08806

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GGTG_08806	GGTG_08806T0	GGTG_08806T0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.30e-53	181.4	23	525

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllv..GagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahee 95
           YDRQ+rlw + +q++l+sa+ llv  G g++G+E+lKnLvl G+g +t++D +tv+ ++l+ +F+++++++gk++A+++ae l elnp v++e   +
   Q: 23   YDRQLRLWAASGQAALESANLLLVnsGSGTVGVETLKNLVLPGIGRFTIFDEATVCEADLGVNFFLDEDSIGKPRAQCCAELLVELNPEVQGEWQPN 119
           ***********************9445789**************************************************************98644 PP
   S: 96   .siteleeeivFfkkf....dvVvla.ldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd.....dppqktiPfctlketpn 181
            +  +l+ e+ ++ +     ++++     + + r  v +  +++  pl+ + + Gl+++ rv ++g   + + ++      ++++  P+++l ++  
   Q: 120  hEAGPLGLEQ-LLGQAspaySLIIYShPISKSDRDLVKSYGRQHGTPLVAVHSAGLYSYFRVELPGTFPIVDTHPdetatTDLRLLGPWPELVDFAK 215
           1445554443.666655666666655056777888899***************************9755555554499999**************66 PP
   S: 182  ...........aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavkafakttins.ikqllksfec 262
                       ++ +++++v++  +le+++++ +++ +++++ek+++++ v+++ +       eenf+ea+++++k  ++ + +s  k+++k++  
   Q: 216  gmtadidgldnHQHGHLPYVVILLYYLEQWKESYDGRYPSTYAEKTAFRKIVSEAQRRdnaeGGEENFDEAVAAVLKTISPPSLPSgLKEVFKYLDT 312
           66666666666**************************************99987777655555699****************************998 PP
   S: 263  divtkskspfwv....................................................................sfcsnaealq....... 284
            +    k +fwv                                                                     fc+na+ ++       
   Q: 313  HK-DAAKGSFWViaaavgafwekhqclpvpgkvpdmkaqssvyiqlqniykakarrdvaevletvrsspggggiepaeveLFCKNAAFVKlinatet 408
           77.889999***********************************************************************88888888887666555 PP
   S: 285  ......vpekvekdeevvkasaplylllralerfekkkgrkpgelsfekddds.....avdlvtaaanlraeslgiepkldddlikeiagniipaia 370
                    +v+  e +++a+   ++++  l+++          ls   dd+      ++  ++++    a++  +      ++ +e+a+   ++++
   Q: 409  gpsadrL-ASVVAAELANDAN--AEAMMMPLSLVPIYMA-----LSATADDPAataedIMGTMRDMVPSAASNDRLV-----KAAEEVARASGGELH 492
           4443321.2222222222222..2222222222222222.....222222221121115555555553222222222.....35678888889**** PP
   S: 371  ttnavvgGlaaqEviKvvsgkfeplknfflfda 403
            ++a  gG++aqEviK+++++++p++n+ +fd+
   Q: 493  NISALTGGMVAQEVIKIITKQYTPVDNTCIFDG 525
           *******************************97 PP

Organism

Gaeumannomyces graminis

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MTEVVAGQTP PALHRPSEKE KKYDRQLRLW AASGQAALES ANLLLVNSGS GTVGVETLKN 60
LVLPGIGRFT IFDEATVCEA DLGVNFFLDE DSIGKPRAQC CAELLVELNP EVQGEWQPNH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGAAG TCGTGGCCGG CCAGACCCCA CCGGCCCTCC ATCGACCGTC GGAAAAGGAA 60
AAGAAGTACG ACAGGCAGCT GCGCCTGTGG GCGGCCAGCG GCCAGGCGGC GCTCGAGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	32.85	1.00e-66	245.00
IUUC-Aml-002333	Ailuropoda melanoleuca	35.15	8.00e-75	273.00
IUUC-Atr-002644	Amborella trichopoda	32.23	2.00e-60	225.00
IUUC-Apl-003446	Anas platyrhynchos	32.90	3.00e-65	240.00
IUUC-Aca-004450	Anolis carolinensis	33.10	2.00e-74	271.00
IUUC-Aly-006187	Arabidopsis lyrata	31.78	7.00e-62	229.00
IUUC-Ath-006692	Arabidopsis thaliana	32.22	1.00e-64	238.00
IUUC-Ago-007900	Ashbya gossypii	25.48	1.00e-33	135.00
IUUC-Acl-008333	Aspergillus clavatus	45.86	1.00e-128	451.00
IUUC-Afl-008529	Aspergillus flavus	47.36	4.00e-130	456.00
IUUC-Afu-009071	Aspergillus fumigatus	47.26	1.00e-133	468.00
IUUC-Ani-009443	Aspergillus nidulans	45.34	1.00e-124	438.00
IUUC-Ang-009669	Aspergillus niger	46.91	7.00e-143	499.00
IUUC-Aor-009914	Aspergillus oryzae	47.28	2.00e-129	454.00
IUUC-Ate-010450	Aspergillus terreus	46.74	3.00e-135	473.00
IUUC-Ame-011183	Astyanax mexicanus	33.03	4.00e-73	267.00
IUUC-Bgr-012111	Blumeria graminis	51.72	1.00e-146	511.00
IUUC-Bta-012583	Bos taurus	34.55	6.00e-76	276.00
IUUC-Bci-013892	Botrytis cinerea	62.95	1.00e-179	621.00
IUUC-Bdi-014592	Brachypodium distachyon	33.03	3.00e-65	241.00
IUUC-Bol-015487	Brassica oleracea	31.32	4.00e-64	237.00
IUUC-Bra-017506	Brassica rapa	31.96	2.00e-62	231.00
IUUC-Cel-018456	Caenorhabditis elegans	29.86	1.00e-56	212.00
IUUC-Cja-020007	Callithrix jacchus	34.36	3.00e-74	270.00
IUUC-Cfa-020324	Canis familiaris	35.28	9.00e-77	279.00
IUUC-Cpo-022248	Cavia porcellus	30.97	1.00e-38	152.00
IUUC-Csa-023149	Chlorocebus sabaeus	29.57	7.00e-50	189.00
IUUC-Cho-024537	Choloepus hoffmanni	27.87	1.00e-36	145.00
IUUC-Cin-025763	Ciona intestinalis	31.69	1.00e-74	272.00
IUUC-Csv-026113	Ciona savignyi	33.70	2.00e-77	281.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	61.44	0.00e+00	635.00
IUUC-Cne-026884	Cryptococcus neoformans	30.40	3.00e-54	204.00
IUUC-Dre-028140	Danio rerio	34.69	3.00e-75	274.00
IUUC-Dno-030033	Dasypus novemcinctus	38.12	1.00e-66	245.00
IUUC-Dor-030513	Dipodomys ordii	57.43	6.00e-25	107.00
IUUC-Dse-031536	Dothistroma septosporum	41.65	3.00e-122	430.00
IUUC-Dme-031683	Drosophila melanogaster	33.33	1.00e-65	242.00
IUUC-Ete-032420	Echinops telfairi	30.91	4.00e-58	217.00
IUUC-Eca-033992	Equus caballus	31.41	2.00e-48	184.00
IUUC-Eeu-034713	Erinaceus europaeus	58.16	4.00e-26	111.00
IUUC-Fca-036548	Felis catus	34.55	1.00e-74	272.00
IUUC-Fal-037600	Ficedula albicollis	32.46	5.00e-65	240.00
IUUC-Fox-038037	Fusarium oxysporum	63.02	0.00e+00	666.00
IUUC-Fso-038387	Fusarium solani	63.79	0.00e+00	688.00
IUUC-Gmo-038562	Gadus morhua	33.70	2.00e-76	278.00
IUUC-Gga-041129	Gallus gallus	33.64	2.00e-72	264.00
IUUC-Gac-042558	Gasterosteus aculeatus	34.51	9.00e-74	269.00
IUUC-Gma-043610	Glycine max	32.72	4.00e-64	237.00
IUUC-Ggo-045611	Gorilla gorilla	34.49	4.00e-74	270.00
IUUC-Hsa-046563	Homo sapiens	34.86	4.00e-76	277.00
IUUC-Hvu-047790	Hordeum vulgare	31.67	7.00e-42	163.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	34.25	4.00e-74	270.00
IUUC-Kpa-049309	Komagataella pastoris	32.50	1.00e-61	228.00
IUUC-Lch-050038	Latimeria chalumnae	33.33	1.00e-71	262.00
IUUC-Lpe-051535	Leersia perrieri	29.92	4.00e-49	187.00
IUUC-Loc-051917	Lepisosteus oculatus	31.50	4.00e-59	220.00
IUUC-Lma-053112	Leptosphaeria maculans	45.77	6.00e-136	476.00
IUUC-Laf-053690	Loxodonta africana	34.96	1.00e-76	278.00
IUUC-Mcc-055117	Macaca mulatta	33.45	2.00e-69	255.00
IUUC-Meu-056761	Macropus eugenii	32.15	3.00e-38	151.00
IUUC-Mor-057230	Magnaporthe oryzae	72.71	0.00e+00	815.00
IUUC-Mpo-057514	Magnaporthe poae	93.83	0.00e+00	982.00
IUUC-Mtr-058551	Medicago truncatula	32.56	2.00e-63	235.00
IUUC-Mla-059183	Melampsora laricipopulina	34.62	9.00e-79	286.00
IUUC-Mga-060144	Meleagris gallopavo	32.71	2.00e-67	248.00
IUUC-Mvi-060221	Microbotryum violaceum	36.32	5.00e-61	227.00
IUUC-Mmr-061325	Microcebus murinus	33.03	2.00e-70	258.00
IUUC-Mdo-062532	Monodelphis domestica	35.09	1.00e-75	275.00
IUUC-Mmu-063956	Mus musculus	34.19	6.00e-76	276.00
IUUC-Mac-064521	Musa acuminata	33.52	7.00e-69	253.00
IUUC-Mpu-066716	Mustela putorius furo	38.06	1.00e-66	246.00
IUUC-Mlu-067459	Myotis lucifugus	34.07	2.00e-75	275.00
IUUC-Nfi-068245	Neosartorya fischeri	47.43	3.00e-133	467.00
IUUC-Ncr-068910	Neurospora crassa	62.32	0.00e+00	684.00
IUUC-Nle-070034	Nomascus leucogenys	32.53	6.00e-66	243.00
IUUC-Opr-070552	Ochotona princeps	34.50	4.00e-35	140.00
IUUC-Ont-071426	Oreochromis niloticus	35.12	6.00e-77	280.00
IUUC-Oan-073389	Ornithorhynchus anatinus	31.22	5.00e-45	173.00
IUUC-Ocu-074911	Oryctolagus cuniculus	33.94	1.00e-74	271.00
IUUC-Oba-075437	Oryza barthii	31.68	2.00e-59	221.00
IUUC-Obr-076684	Oryza brachyantha	31.30	4.00e-54	204.00
IUUC-Ogl-077170	Oryza glaberrima	31.68	2.00e-59	221.00
IUUC-Ogu-078844	Oryza glumaepatula	31.03	1.00e-51	195.00
IUUC-Oin-079105	Oryza indica	31.68	2.00e-59	222.00
IUUC-Olo-080943	Oryza longistaminata	29.87	5.00e-46	177.00
IUUC-Oni-082891	Oryza nivara	30.59	1.00e-53	202.00
IUUC-Opu-083457	Oryza punctata	31.87	7.00e-59	219.00
IUUC-Oru-084960	Oryza rufipogon	29.81	3.00e-46	177.00
IUUC-Osa-085358	Oryza sativa	31.68	5.00e-59	220.00
IUUC-Ola-086420	Oryzias latipes	30.62	7.00e-45	172.00
IUUC-Olu-087625	Ostreococcus lucimarinus	27.07	5.00e-41	160.00
IUUC-Oga-088810	Otolemur garnettii	34.98	1.00e-76	279.00
IUUC-Oar-089196	Ovis aries	34.54	7.00e-75	273.00
IUUC-Ptr-090617	Pan troglodytes	34.86	1.00e-75	275.00
IUUC-Pan-092761	Papio anubis	34.55	2.00e-75	275.00
IUUC-Psi-093191	Pelodiscus sinensis	30.98	3.00e-64	238.00
IUUC-Pma-094380	Petromyzon marinus	35.02	2.00e-64	238.00
IUUC-Pno-095084	Phaeosphaeria nodorum	43.35	4.00e-119	421.00
IUUC-Ppa-095875	Physcomitrella patens	32.12	1.00e-63	236.00
IUUC-Pfo-096467	Poecilia formosa	34.07	8.00e-72	263.00
IUUC-Pab-098255	Pongo abelii	36.66	4.00e-66	243.00
IUUC-Pop-099871	Populus trichocarpa	31.32	5.00e-65	240.00
IUUC-Pca-100807	Procavia capensis	37.88	3.00e-24	104.00
IUUC-Ppe-101280	Prunus persica	32.90	2.00e-68	251.00
IUUC-Pva-102333	Pteropus vampyrus	34.36	2.00e-70	258.00
IUUC-Pgr-103401	Puccinia graminis	29.12	1.00e-63	235.00
IUUC-Ptt-103889	Puccinia triticina	28.21	8.00e-59	219.00
IUUC-Pte-104355	Pyrenophora teres	46.98	1.00e-135	474.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	46.46	7.00e-134	469.00
IUUC-Rno-105810	Rattus norvegicus	34.01	5.00e-75	273.00
IUUC-Sce-106397	Saccharomyces cerevisiae	23.29	9.00e-27	112.00
IUUC-Sha-106770	Sarcophilus harrisii	39.20	5.00e-48	182.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	31.25	8.00e-65	239.00
IUUC-Spo-108276	Schizosaccharomyces pombe	31.42	1.00e-65	242.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	61.75	0.00e+00	641.00
IUUC-Smo-109213	Selaginella moellendorffii	33.88	4.00e-68	250.00
IUUC-Sit-110157	Setaria italica	32.23	4.00e-67	247.00
IUUC-Sly-111660	Solanum lycopersicum	30.96	9.00e-60	222.00
IUUC-Stu-112469	Solanum tuberosum	32.07	2.00e-66	245.00
IUUC-Sar-113083	Sorex araneus	25.93	7.00e-35	140.00
IUUC-Sbi-113813	Sorghum bicolor	32.10	8.00e-66	243.00
IUUC-Sre-115058	Sporisorium reilianum	36.08	9.00e-60	223.00
IUUC-Tgu-116772	Taeniopygia guttata	32.54	8.00e-66	243.00
IUUC-Tru-118686	Takifugu rubripes	33.58	2.00e-72	265.00
IUUC-Tsy-119111	Tarsius syrichta	36.43	1.00e-37	149.00
IUUC-Tni-120231	Tetraodon nigroviridis	31.67	2.00e-64	238.00
IUUC-Tca-121491	Theobroma cacao	32.72	5.00e-60	223.00
IUUC-Tre-122103	Trichoderma reesei	61.64	0.00e+00	682.00
IUUC-Tvi-122672	Trichoderma virens	62.20	0.00e+00	664.00
IUUC-Tae-125316	Triticum aestivum	33.33	2.00e-67	248.00
IUUC-Tur-126487	Triticum urartu	32.10	5.00e-62	230.00
IUUC-Tme-127097	Tuber melanosporum	40.36	7.00e-96	342.00
IUUC-Ttr-128465	Tursiops truncatus	32.18	7.00e-60	223.00
IUUC-Uma-129645	Ustilago maydis	36.12	2.00e-61	228.00
IUUC-Vda-129989	Verticillium dahliae	55.88	4.00e-160	556.00
IUUC-Vpa-130529	Vicugna pacos	33.27	8.00e-65	239.00
IUUC-Vvi-131059	Vitis vinifera	33.27	1.00e-66	245.00
IUUC-Xtr-132002	Xenopus tropicalis	32.84	8.00e-73	266.00
IUUC-Xma-133930	Xiphophorus maculatus	34.94	1.00e-73	268.00
IUUC-Yli-134505	Yarrowia lipolytica	36.29	1.00e-81	295.00
IUUC-Zma-135619	Zea mays	31.87	3.00e-64	237.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence