iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-30	103.9	120	151
UBD/Beta-Prp	1.20e-51	176.0	41	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gHt  v+ ++f  d  ++vsG+dD t+k+WD+
   Q: 120  GHTKAVHTVDFtADkYHVVSGADDYTVKLWDI 151
           8***********77799**************6 PP

UBD/Beta-Prp

   S: 13   itcvkf..spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvls 99
           +++v+f   p +++ +t+  +++i ++   ++  ++++s  +++ ++ +f +dg++lv gseD++++++d+s + +++ ++gh++ v +
   Q: 41   VSKVDFspQPPYNYAVTA--SSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHT 127
           7889**444555555555..6******************************************************************** PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls 187
           ++f ++++++vsG +d t+++wd+++ +++  t+++h++ v+c + ++ + +l+v+Gs+D tv+++d +t+k +   +  h ++v+s+ 
   Q: 128  VDFTADKYHVVSGADDYTVKLWDIPNSKEIL-TFKEHSDYVRCGCASKLNpDLFVTGSYDHTVKMFDARTNKNVLCVE--HGQPVESVL 213
           *******************************.****************************************999994..9******** PP
   S: 188  fdsngkelvsgsldgtvklwdl 209
           + ++g  lvs+   ++vk+wd+
   Q: 214  LFPSGGLLVSA-GGRYVKVWDM 234
           99988666665.679*****97 PP

Organism

Rattus norvegicus

Functional Description
(View)

Involved in nucleolar processing of pre-18S ribosomal RNA.

Protein Sequence
(Fasta)

MAGYKPVVIQ TYPVLGEKIT QDTLYWNNYK TPVQIKEFGA VSKVDFSPQP PYNYAVTASS 60
RIHIYGRYSQ EPVKTFSRFK DTAYCATFRQ DGQLLVAGSE DGVVQLFDIS GRAPLRQFEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGATTTTGA GCGAGTGCTT CTGAGTGGTC TGCTGTAGGG AGCTGGCGAA GTCTGGGGAG 60
TCGTCCTGGG GATCGGGGTG CCTCGGCGGA CCCTCGGTGC CCCGCGGAGG TAGGCGATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR018983--U3_snoRNA-assocProt_15_C
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09384--UTP15_C
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0001650--C:fibrillar center
GO:0005730--C:nucleolus
GO:0003723--F:RNA binding
GO:0006364--P:rRNA processing

KEGG

rno:310019

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002117	Ailuropoda melanoleuca	92.08	0.00e+00	942.00
IUUC-Atr-003068	Amborella trichopoda	33.40	2.00e-69	256.00
IUUC-Apl-003926	Anas platyrhynchos	70.11	0.00e+00	697.00
IUUC-Aca-004271	Anolis carolinensis	70.35	0.00e+00	722.00
IUUC-Aly-005525	Arabidopsis lyrata	33.93	7.00e-62	231.00
IUUC-Ath-006954	Arabidopsis thaliana	33.93	2.00e-62	233.00
IUUC-Ago-007973	Ashbya gossypii	31.69	6.00e-67	248.00
IUUC-Acl-008287	Aspergillus clavatus	33.02	5.00e-58	218.00
IUUC-Afl-008504	Aspergillus flavus	31.50	5.00e-66	245.00
IUUC-Afu-008983	Aspergillus fumigatus	32.45	2.00e-55	209.00
IUUC-Ani-009315	Aspergillus nidulans	32.89	2.00e-63	236.00
IUUC-Ang-009690	Aspergillus niger	31.44	7.00e-64	238.00
IUUC-Aor-010181	Aspergillus oryzae	31.50	5.00e-66	245.00
IUUC-Ate-010498	Aspergillus terreus	31.31	3.00e-60	226.00
IUUC-Ame-011814	Astyanax mexicanus	60.00	5.00e-173	600.00
IUUC-Bgr-012273	Blumeria graminis	31.71	8.00e-73	268.00
IUUC-Bta-013068	Bos taurus	90.75	0.00e+00	942.00
IUUC-Bci-013930	Botrytis cinerea	31.37	2.00e-72	266.00
IUUC-Bdi-014876	Brachypodium distachyon	31.83	2.00e-64	239.00
IUUC-Bol-015366	Brassica oleracea	33.13	3.00e-64	239.00
IUUC-Bra-017589	Brassica rapa	33.13	1.00e-62	233.00
IUUC-Cel-018159	Caenorhabditis elegans	30.26	2.00e-63	236.00
IUUC-Cja-019139	Callithrix jacchus	92.77	0.00e+00	922.00
IUUC-Cfa-020742	Canis familiaris	87.43	0.00e+00	910.00
IUUC-Cpo-021707	Cavia porcellus	92.26	0.00e+00	958.00
IUUC-Cre-022665	Chlamydomonas reinhardtii	40.82	2.00e-89	322.00
IUUC-Csa-023024	Chlorocebus sabaeus	91.63	0.00e+00	946.00
IUUC-Cho-024487	Choloepus hoffmanni	88.81	6.00e-139	487.00
IUUC-Cin-025294	Ciona intestinalis	47.23	2.00e-135	475.00
IUUC-Cgl-026388	Colletotrichum gloeosporioides	29.24	4.00e-41	162.00
IUUC-Cne-026945	Cryptococcus neoformans	38.95	1.00e-82	300.00
IUUC-Cme-027108	Cyanidioschyzon merolae	31.03	9.00e-58	218.00
IUUC-Dre-028316	Danio rerio	58.67	3.00e-176	611.00
IUUC-Dno-028985	Dasypus novemcinctus	91.09	0.00e+00	926.00
IUUC-Dor-030219	Dipodomys ordii	78.77	1.00e-167	582.00
IUUC-Dse-031495	Dothistroma septosporum	31.06	3.00e-49	189.00
IUUC-Dme-031769	Drosophila melanogaster	38.64	6.00e-86	311.00
IUUC-Ete-032630	Echinops telfairi	82.64	0.00e+00	754.00
IUUC-Eca-033816	Equus caballus	92.02	0.00e+00	950.00
IUUC-Eeu-034840	Erinaceus europaeus	79.75	0.00e+00	720.00
IUUC-Fca-035751	Felis catus	91.05	0.00e+00	952.00
IUUC-Fal-036733	Ficedula albicollis	69.15	0.00e+00	744.00
IUUC-Fox-037743	Fusarium oxysporum	30.59	1.00e-65	243.00
IUUC-Fso-038395	Fusarium solani	30.98	8.00e-67	248.00
IUUC-Gmo-038803	Gadus morhua	62.55	0.00e+00	635.00
IUUC-Ggr-040092	Gaeumannomyces graminis	31.20	4.00e-60	226.00
IUUC-Gga-040714	Gallus gallus	71.52	0.00e+00	744.00
IUUC-Gac-042640	Gasterosteus aculeatus	61.43	0.00e+00	660.00
IUUC-Gma-044192	Glycine max	33.07	3.00e-69	256.00
IUUC-Ggo-045616	Gorilla gorilla	88.54	0.00e+00	936.00
IUUC-Hsa-046720	Homo sapiens	89.74	0.00e+00	884.00
IUUC-Itr-048796	Ictidomys tridecemlineatus	92.02	0.00e+00	947.00
IUUC-Kpa-049291	Komagataella pastoris	30.20	1.00e-64	240.00
IUUC-Lch-049729	Latimeria chalumnae	71.78	0.00e+00	739.00
IUUC-Lpe-051141	Leersia perrieri	32.62	3.00e-64	239.00
IUUC-Loc-051756	Lepisosteus oculatus	71.17	0.00e+00	734.00
IUUC-Lma-053083	Leptosphaeria maculans	31.29	9.00e-66	244.00
IUUC-Laf-054067	Loxodonta africana	87.31	0.00e+00	891.00
IUUC-Mcc-055096	Macaca mulatta	91.63	0.00e+00	946.00
IUUC-Meu-056604	Macropus eugenii	72.37	0.00e+00	739.00
IUUC-Mor-057186	Magnaporthe oryzae	30.11	6.00e-63	235.00
IUUC-Mtr-058346	Medicago truncatula	32.81	3.00e-67	249.00
IUUC-Mla-059116	Melampsora laricipopulina	35.89	5.00e-83	301.00
IUUC-Mga-060038	Meleagris gallopavo	63.37	6.00e-148	516.00
IUUC-Mvi-060272	Microbotryum violaceum	33.52	3.00e-80	292.00
IUUC-Mmr-060877	Microcebus murinus	90.35	0.00e+00	933.00
IUUC-Mdo-062168	Monodelphis domestica	80.00	0.00e+00	785.00
IUUC-Mmu-063441	Mus musculus	95.27	0.00e+00	1005.00
IUUC-Mac-065330	Musa acuminata	33.83	1.00e-53	204.00
IUUC-Mpu-065704	Mustela putorius furo	92.28	0.00e+00	950.00
IUUC-Mlu-067640	Myotis lucifugus	90.33	0.00e+00	940.00
IUUC-Nfi-068589	Neosartorya fischeri	32.26	4.00e-55	209.00
IUUC-Ncr-068769	Neurospora crassa	30.60	2.00e-63	236.00
IUUC-Nle-069105	Nomascus leucogenys	85.36	0.00e+00	865.00
IUUC-Opr-070203	Ochotona princeps	88.42	0.00e+00	952.00
IUUC-Ont-072054	Oreochromis niloticus	66.06	0.00e+00	692.00
IUUC-Oan-073624	Ornithorhynchus anatinus	74.16	0.00e+00	683.00
IUUC-Ocu-074326	Oryctolagus cuniculus	89.77	0.00e+00	930.00
IUUC-Obr-076038	Oryza brachyantha	32.90	4.00e-64	239.00
IUUC-Ogl-077463	Oryza glaberrima	30.93	3.00e-59	223.00
IUUC-Ogu-078631	Oryza glumaepatula	31.59	4.00e-66	245.00
IUUC-Oin-079242	Oryza indica	31.13	5.00e-60	225.00
IUUC-Olo-080652	Oryza longistaminata	29.69	3.00e-55	209.00
IUUC-Ome-081109	Oryza meridionalis	32.20	5.00e-57	216.00
IUUC-Oni-082187	Oryza nivara	31.13	5.00e-60	225.00
IUUC-Opu-083995	Oryza punctata	32.33	6.00e-59	221.00
IUUC-Oru-084962	Oryza rufipogon	32.46	2.00e-56	213.00
IUUC-Osa-086201	Oryza sativa	32.46	2.00e-56	213.00
IUUC-Ola-087115	Oryzias latipes	65.45	0.00e+00	683.00
IUUC-Olu-087842	Ostreococcus lucimarinus	33.86	3.00e-71	262.00
IUUC-Oga-088204	Otolemur garnettii	90.47	0.00e+00	933.00
IUUC-Oar-089297	Ovis aries	90.77	0.00e+00	938.00
IUUC-Ptr-090953	Pan troglodytes	92.02	0.00e+00	951.00
IUUC-Pan-092451	Papio anubis	87.89	0.00e+00	922.00
IUUC-Psi-092999	Pelodiscus sinensis	74.95	0.00e+00	766.00
IUUC-Pma-094304	Petromyzon marinus	46.37	2.00e-127	449.00
IUUC-Pno-095060	Phaeosphaeria nodorum	30.92	7.00e-65	241.00
IUUC-Ppa-095433	Physcomitrella patens	37.94	5.00e-97	348.00
IUUC-Pfo-096433	Poecilia formosa	63.44	0.00e+00	661.00
IUUC-Pab-098677	Pongo abelii	91.05	0.00e+00	942.00
IUUC-Pop-099329	Populus trichocarpa	33.74	6.00e-64	238.00
IUUC-Pca-100444	Procavia capensis	80.89	0.00e+00	763.00
IUUC-Ppe-101318	Prunus persica	32.32	4.00e-76	278.00
IUUC-Pva-102162	Pteropus vampyrus	81.32	0.00e+00	853.00
IUUC-Pgr-103329	Puccinia graminis	41.21	4.00e-65	242.00
IUUC-Ptt-103837	Puccinia triticina	32.84	3.00e-80	292.00
IUUC-Pte-104133	Pyrenophora teres	31.05	6.00e-66	244.00
IUUC-Pyt-104675	Pyrenophora triticirepentis	30.86	2.00e-65	243.00
IUUC-Sce-106443	Saccharomyces cerevisiae	29.84	9.00e-66	244.00
IUUC-Sha-107199	Sarcophilus harrisii	78.68	0.00e+00	836.00
IUUC-Sja-107670	Schizosaccharomyces japonicus	38.76	3.00e-96	345.00
IUUC-Spo-108125	Schizosaccharomyces pombe	37.96	2.00e-90	326.00
IUUC-Ssl-108534	Sclerotinia sclerotiorum	31.18	2.00e-71	263.00
IUUC-Smo-109588	Selaginella moellendorffii	37.03	9.00e-93	333.00
IUUC-Sit-110043	Setaria italica	31.02	4.00e-47	182.00
IUUC-Stu-112396	Solanum tuberosum	35.10	6.00e-82	298.00
IUUC-Sar-113359	Sorex araneus	90.10	2.00e-157	548.00
IUUC-Sre-114995	Sporisorium reilianum	34.57	1.00e-84	307.00
IUUC-Ssc-115397	Sus scrofa	90.66	0.00e+00	941.00
IUUC-Tgu-116834	Taeniopygia guttata	68.91	0.00e+00	747.00
IUUC-Tru-118764	Takifugu rubripes	63.62	0.00e+00	689.00
IUUC-Tsy-119118	Tarsius syrichta	91.05	0.00e+00	945.00
IUUC-Tni-120053	Tetraodon nigroviridis	63.82	0.00e+00	693.00
IUUC-Tca-121842	Theobroma cacao	34.80	1.00e-72	267.00
IUUC-Tre-122172	Trichoderma reesei	32.81	3.00e-68	252.00
IUUC-Tvi-122288	Trichoderma virens	31.78	3.00e-56	213.00
IUUC-Tae-124909	Triticum aestivum	32.68	2.00e-52	200.00
IUUC-Tur-126846	Triticum urartu	31.07	3.00e-29	122.00
IUUC-Tme-127164	Tuber melanosporum	32.52	3.00e-72	265.00
IUUC-Tbe-127458	Tupaia belangeri	91.12	0.00e+00	885.00
IUUC-Ttr-128680	Tursiops truncatus	90.17	0.00e+00	909.00
IUUC-Uma-129508	Ustilago maydis	35.30	3.00e-84	306.00
IUUC-Vda-129696	Verticillium dahliae	35.63	1.00e-52	200.00
IUUC-Vpa-130820	Vicugna pacos	91.09	0.00e+00	931.00
IUUC-Vvi-131126	Vitis vinifera	34.47	8.00e-86	311.00
IUUC-Xtr-131826	Xenopus tropicalis	67.32	0.00e+00	729.00
IUUC-Xma-133373	Xiphophorus maculatus	64.21	0.00e+00	674.00
IUUC-Yli-134432	Yarrowia lipolytica	31.64	2.00e-71	262.00
IUUC-Zma-135241	Zea mays	31.30	6.00e-58	218.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence