• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-064386
UUCD1 version UUC-MuM-00876
Ensembl Protein ID ENSMUSP00000070927.5
UniProt Accession Q99ME2; WDR6_MOUSE
Genbank Protein ID AAK31166.1; BAC29740.1; BAE27306.1; BAE37480.1; EDL21306.1; AAH50894.1; AAH54367.1
Protein Name WD repeat-containing protein 6
Genbank Nucleotide ID AF348591; AK037181; AK146617; AK163752; CH466560; BC050894; BC054367
Gene Name Wdr6
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000066357.6 ENSMUST00000068700.6 ENSMUSP00000070927.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 4.40e-24 84.7 917 954
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 6    vtcla.f....sd.tl...lvsGsdDgtikvWDlrtgv 34
           v  ++ f    ++ ++   l+s++ Dg++  WDl+t  
   Q: 917  VLKVHsFtheaPNqRRrliLCSAATDGSLAFWDLTTAM 954
           555554666663321134479999**********9975 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.
 Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.
Protein Sequence
(Fasta)
MDAFGDYVWP RATSELILLP VTGLECVGDR LLAGEGPDLL VYNLDLGGHL RMVKRVQNLL 60
GHFLIHGFRV RPEPKGDLDS EAMIAVFGSK GLKVVKVSWG QSHLRELWRS GLWNMSDWIW 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064386|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTGGACGTCC GCAGCCCAGC GCCAGGGCTT TGCTACCTGT AGCTAAGGGC TTCGGAGCTC 60
TGCAGCGCGG CTCTCCAGAC GGCTGGTTCT CGCGAGAACG CAGCTCTCTT CTTGTCCGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064386|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0131--Cell cycle
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0003723--F:RNA binding
GO:0007050--P:cell cycle arrest
GO:0010507--P:negative regulation of autophagy
GO:0008285--P:negative regulation of cell proliferation
KEGG mmu:83669
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000976 Aegilops tauschii 21.69 9.00e-21 96.30
IUUC-Aml-001786 Ailuropoda melanoleuca 87.29 0.00e+00 1952.00
IUUC-Atr-003053 Amborella trichopoda 22.70 4.00e-33 137.00
IUUC-Apl-003178 Anas platyrhynchos 47.44 6.00e-142 497.00
IUUC-Aca-004886 Anolis carolinensis 44.59 0.00e+00 856.00
IUUC-Aly-005509 Arabidopsis lyrata 24.47 1.00e-36 149.00
IUUC-Ath-007109 Arabidopsis thaliana 24.00 5.00e-35 143.00
IUUC-Ago-007817 Ashbya gossypii 21.97 1.00e-40 162.00
IUUC-Acl-008020 Aspergillus clavatus 21.68 3.00e-30 127.00
IUUC-Afl-008608 Aspergillus flavus 21.37 8.00e-16 79.30
IUUC-Afu-009035 Aspergillus fumigatus 22.32 2.00e-32 135.00
IUUC-Ani-009359 Aspergillus nidulans 21.90 2.00e-20 95.10
IUUC-Ang-009692 Aspergillus niger 20.83 3.00e-22 101.00
IUUC-Aor-010056 Aspergillus oryzae 21.35 6.00e-26 113.00
IUUC-Ate-010299 Aspergillus terreus 22.72 5.00e-28 120.00
IUUC-Ame-011051 Astyanax mexicanus 33.61 2.00e-151 530.00
IUUC-Bgr-012077 Blumeria graminis 27.21 4.00e-08 54.30
IUUC-Bta-012793 Bos taurus 84.88 0.00e+00 1876.00
IUUC-Bci-013679 Botrytis cinerea 21.34 8.00e-10 60.10
IUUC-Bdi-014401 Brachypodium distachyon 23.28 1.00e-34 142.00
IUUC-Bol-015628 Brassica oleracea 23.70 1.00e-27 119.00
IUUC-Bra-017446 Brassica rapa 24.17 6.00e-32 133.00
IUUC-Cja-018910 Callithrix jacchus 85.96 0.00e+00 1945.00
IUUC-Cfa-021260 Canis familiaris 87.47 0.00e+00 1961.00
IUUC-Cpo-022205 Cavia porcellus 84.18 0.00e+00 1925.00
IUUC-Csa-023510 Chlorocebus sabaeus 85.33 0.00e+00 1907.00
IUUC-Cgl-026380 Colletotrichum gloeosporioides 29.09 8.00e-08 52.80
IUUC-Dre-028004 Danio rerio 33.44 3.00e-156 546.00
IUUC-Dno-029804 Dasypus novemcinctus 80.83 0.00e+00 1793.00
IUUC-Dor-030512 Dipodomys ordii 81.39 0.00e+00 1440.00
IUUC-Dme-032047 Drosophila melanogaster 24.24 4.00e-26 114.00
IUUC-Ete-033076 Echinops telfairi 78.04 0.00e+00 666.00
IUUC-Eca-033727 Equus caballus 86.50 0.00e+00 1547.00
IUUC-Eeu-035210 Erinaceus europaeus 79.82 0.00e+00 1818.00
IUUC-Fca-035433 Felis catus 87.11 0.00e+00 1963.00
IUUC-Fal-036807 Ficedula albicollis 45.90 4.00e-164 571.00
IUUC-Fox-037749 Fusarium oxysporum 21.79 4.00e-17 84.00
IUUC-Fso-038164 Fusarium solani 23.54 1.00e-16 82.40
IUUC-Gmo-039180 Gadus morhua 34.73 4.00e-141 496.00
IUUC-Ggr-039801 Gaeumannomyces graminis 27.37 9.00e-05 43.50
IUUC-Gga-040482 Gallus gallus 43.79 1.00e-178 620.00
IUUC-Gac-042066 Gasterosteus aculeatus 34.80 7.00e-149 521.00
IUUC-Gma-042704 Glycine max 23.47 1.00e-28 122.00
IUUC-Ggo-044942 Gorilla gorilla 86.40 0.00e+00 1925.00
IUUC-Hsa-046408 Homo sapiens 86.49 0.00e+00 1952.00
IUUC-Hvu-047448 Hordeum vulgare 22.17 3.00e-25 110.00
IUUC-Itr-048756 Ictidomys tridecemlineatus 87.38 0.00e+00 2015.00
IUUC-Kpa-049257 Komagataella pastoris 21.34 2.00e-38 155.00
IUUC-Lch-050170 Latimeria chalumnae 42.09 0.00e+00 876.00
IUUC-Lpe-051575 Leersia perrieri 21.79 2.00e-30 129.00
IUUC-Loc-052341 Lepisosteus oculatus 35.62 7.00e-137 481.00
IUUC-Lma-053318 Leptosphaeria maculans 24.42 1.00e-12 69.30
IUUC-Laf-054299 Loxodonta africana 82.76 0.00e+00 1852.00
IUUC-Mcc-055438 Macaca mulatta 85.51 0.00e+00 1910.00
IUUC-Meu-056206 Macropus eugenii 46.57 0.00e+00 635.00
IUUC-Mor-056928 Magnaporthe oryzae 23.03 2.00e-12 68.90
IUUC-Mpo-057438 Magnaporthe poae 26.09 2.00e-04 41.60
IUUC-Mtr-058455 Medicago truncatula 25.21 4.00e-28 121.00
IUUC-Mga-059962 Meleagris gallopavo 46.26 3.00e-153 535.00
IUUC-Mvi-060438 Microbotryum violaceum 26.10 1.00e-15 79.30
IUUC-Mmr-061353 Microcebus murinus 86.40 0.00e+00 1966.00
IUUC-Mdo-062061 Monodelphis domestica 49.73 0.00e+00 897.00
IUUC-Mac-065653 Musa acuminata 23.33 9.00e-43 169.00
IUUC-Mpu-066420 Mustela putorius furo 87.02 0.00e+00 1974.00
IUUC-Mlu-068104 Myotis lucifugus 83.29 0.00e+00 1875.00
IUUC-Nfi-068301 Neosartorya fischeri 22.31 1.00e-33 139.00
IUUC-Ncr-068718 Neurospora crassa 22.78 2.00e-13 72.40
IUUC-Nle-069836 Nomascus leucogenys 86.04 0.00e+00 1441.00
IUUC-Ont-071605 Oreochromis niloticus 34.76 9.00e-161 561.00
IUUC-Oan-073645 Ornithorhynchus anatinus 47.94 0.00e+00 984.00
IUUC-Ocu-074708 Oryctolagus cuniculus 84.36 0.00e+00 1859.00
IUUC-Oba-075290 Oryza barthii 25.69 2.00e-21 98.60
IUUC-Obr-076647 Oryza brachyantha 22.71 3.00e-31 130.00
IUUC-Ogl-077628 Oryza glaberrima 27.08 2.00e-27 118.00
IUUC-Ogu-078209 Oryza glumaepatula 25.69 1.00e-21 99.40
IUUC-Oin-079342 Oryza indica 27.22 2.00e-28 121.00
IUUC-Olo-080623 Oryza longistaminata 26.13 5.00e-25 108.00
IUUC-Ome-081776 Oryza meridionalis 24.36 2.00e-21 99.00
IUUC-Oni-082311 Oryza nivara 27.22 2.00e-28 121.00
IUUC-Opu-083195 Oryza punctata 26.50 6.00e-27 116.00
IUUC-Oru-085006 Oryza rufipogon 25.38 6.00e-21 97.10
IUUC-Osa-085317 Oryza sativa 26.79 9.00e-27 116.00
IUUC-Ola-087145 Oryzias latipes 35.15 1.00e-144 508.00
IUUC-Olu-087785 Ostreococcus lucimarinus 26.83 2.00e-11 65.50
IUUC-Oga-088206 Otolemur garnettii 86.31 0.00e+00 1986.00
IUUC-Oar-089802 Ovis aries 84.10 0.00e+00 1850.00
IUUC-Ptr-091528 Pan troglodytes 78.40 0.00e+00 1719.00
IUUC-Pan-092782 Papio anubis 85.87 0.00e+00 1925.00
IUUC-Psi-093102 Pelodiscus sinensis 47.30 2.00e-134 473.00
IUUC-Pno-095063 Phaeosphaeria nodorum 25.81 2.00e-06 48.10
IUUC-Ppa-095436 Physcomitrella patens 24.30 8.00e-38 153.00
IUUC-Pfo-097423 Poecilia formosa 33.80 5.00e-143 502.00
IUUC-Pab-097763 Pongo abelii 86.40 0.00e+00 1924.00
IUUC-Pop-099090 Populus trichocarpa 27.01 2.00e-25 112.00
IUUC-Pca-100173 Procavia capensis 81.69 0.00e+00 1824.00
IUUC-Ppe-101580 Prunus persica 24.11 3.00e-29 124.00
IUUC-Pva-102715 Pteropus vampyrus 86.13 0.00e+00 1900.00
IUUC-Pgr-103424 Puccinia graminis 24.41 8.00e-14 73.20
IUUC-Pte-104316 Pyrenophora teres 23.28 8.00e-12 66.60
IUUC-Pyt-104676 Pyrenophora triticirepentis 23.71 7.00e-11 63.50
IUUC-Rno-105122 Rattus norvegicus 94.31 0.00e+00 2172.00
IUUC-Sce-106465 Saccharomyces cerevisiae 21.23 9.00e-29 122.00
IUUC-Sha-107208 Sarcophilus harrisii 48.29 0.00e+00 1011.00
IUUC-Sja-107771 Schizosaccharomyces japonicus 34.81 3.00e-18 87.80
IUUC-Spo-108272 Schizosaccharomyces pombe 22.40 5.00e-20 93.60
IUUC-Ssl-108576 Sclerotinia sclerotiorum 21.70 4.00e-06 47.40
IUUC-Smo-108961 Selaginella moellendorffii 23.64 4.00e-44 174.00
IUUC-Sit-109932 Setaria italica 22.73 9.00e-34 139.00
IUUC-Sly-111685 Solanum lycopersicum 23.56 9.00e-34 139.00
IUUC-Sar-112998 Sorex araneus 83.93 0.00e+00 1912.00
IUUC-Sbi-114074 Sorghum bicolor 22.34 3.00e-35 144.00
IUUC-Ssc-115619 Sus scrofa 86.27 0.00e+00 934.00
IUUC-Tgu-117485 Taeniopygia guttata 46.08 5.00e-158 551.00
IUUC-Tru-118104 Takifugu rubripes 35.89 4.00e-164 572.00
IUUC-Tni-119995 Tetraodon nigroviridis 36.13 2.00e-157 550.00
IUUC-Tca-121790 Theobroma cacao 26.90 9.00e-25 109.00
IUUC-Tre-122080 Trichoderma reesei 20.81 5.00e-11 63.90
IUUC-Tvi-122306 Trichoderma virens 21.71 1.00e-12 68.90
IUUC-Tae-125371 Triticum aestivum 23.32 6.00e-37 150.00
IUUC-Tur-126787 Triticum urartu 23.70 9.00e-31 129.00
IUUC-Tbe-128082 Tupaia belangeri 88.54 5.00e-152 531.00
IUUC-Ttr-128387 Tursiops truncatus 89.94 0.00e+00 968.00
IUUC-Vda-129804 Verticillium dahliae 21.29 4.00e-09 57.40
IUUC-Vpa-130257 Vicugna pacos 85.48 4.00e-156 545.00
IUUC-Vvi-131701 Vitis vinifera 28.44 8.00e-28 120.00
IUUC-Xtr-132622 Xenopus tropicalis 41.96 0.00e+00 864.00
IUUC-Xma-134014 Xiphophorus maculatus 34.94 2.00e-153 536.00
IUUC-Yli-134589 Yarrowia lipolytica 22.15 2.00e-26 115.00
IUUC-Zma-135732 Zea mays 21.51 5.00e-37 150.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved