iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066107

Ensembl Protein ID

ENSMPUP00000012121.1

UniProt Accession

M3YLB4; M3YLB4_MUSPF

Genbank Protein ID

ENSMPUP00000012121

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01074231

Gene Name

SYVN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000012218.1	ENSMPUT00000012321.1	ENSMPUP00000012121.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.10e-09	37.7	291	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC+e++ +g + lpC+H+fh++Cl  w       +++++CP+Cr
   Q: 291  CIICREEMVTGAKRLPCNHIFHTSCLRSW------FQRQQTCPTCR 330
           ********99999****************......**********8 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MFRTAVMMAA SLALTGAVVA HAYYLKHQFY PTVVYLTKSS PSMAVLYIQA FVLVFLLGKV 60
MGKVFFGQLR AAEMEHLLER SWYAVTETCL AFTVFRDDFS PRFVALFTLL LFLKCFHWLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTCCAGGC CAGGGCAATG TTCCGCACCG CAGTGATGAT GGCGGCCAGC CTGGCGCTGA 60
CCGGGGCCGT GGTGGCTCAT GCCTACTACC TCAAGCACCA GTTCTACCCC ACTGTGGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR032832--E3_lig_synoviolin/Hrd1
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:0016021--C:integral component of membrane
GO:0005654--C:nucleoplasm
GO:0005790--C:smooth endoplasmic reticulum
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:1902236--P:negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0050821--P:protein stabilization
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030970--P:retrograde protein transport, ER to cytosol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000344	Aegilops tauschii	37.28	1.00e-51	197.00
IUUC-Aml-001539	Ailuropoda melanoleuca	99.41	0.00e+00	702.00
IUUC-Atr-002892	Amborella trichopoda	43.30	1.00e-77	284.00
IUUC-Apl-004003	Anas platyrhynchos	95.76	2.00e-65	240.00
IUUC-Aca-004799	Anolis carolinensis	97.81	0.00e+00	660.00
IUUC-Aly-006352	Arabidopsis lyrata	43.43	9.00e-75	274.00
IUUC-Ath-006773	Arabidopsis thaliana	43.43	2.00e-74	273.00
IUUC-Ago-007894	Ashbya gossypii	25.23	4.00e-19	89.70
IUUC-Acl-008041	Aspergillus clavatus	30.53	6.00e-55	209.00
IUUC-Afl-008427	Aspergillus flavus	31.28	9.00e-50	191.00
IUUC-Afu-009023	Aspergillus fumigatus	31.36	1.00e-55	211.00
IUUC-Ani-009133	Aspergillus nidulans	31.50	4.00e-58	219.00
IUUC-Ang-009612	Aspergillus niger	34.30	1.00e-55	211.00
IUUC-Aor-010045	Aspergillus oryzae	30.94	4.00e-56	213.00
IUUC-Ate-010533	Aspergillus terreus	31.65	8.00e-57	215.00
IUUC-Ame-011083	Astyanax mexicanus	93.38	0.00e+00	627.00
IUUC-Bgr-012122	Blumeria graminis	28.31	1.00e-47	185.00
IUUC-Bta-013375	Bos taurus	99.70	0.00e+00	699.00
IUUC-Bci-013675	Botrytis cinerea	37.25	2.00e-23	104.00
IUUC-Bdi-015070	Brachypodium distachyon	42.69	1.00e-68	253.00
IUUC-Bol-015674	Brassica oleracea	43.50	2.00e-74	273.00
IUUC-Bra-017516	Brassica rapa	42.03	1.00e-72	266.00
IUUC-Cel-018422	Caenorhabditis elegans	57.70	5.00e-117	414.00
IUUC-Cja-019779	Callithrix jacchus	97.05	0.00e+00	669.00
IUUC-Cfa-020189	Canis familiaris	99.70	0.00e+00	700.00
IUUC-Cpo-022209	Cavia porcellus	99.41	0.00e+00	699.00
IUUC-Cre-022743	Chlamydomonas reinhardtii	39.24	9.00e-65	240.00
IUUC-Csa-023571	Chlorocebus sabaeus	99.70	0.00e+00	699.00
IUUC-Cho-024889	Choloepus hoffmanni	88.43	1.00e-177	616.00
IUUC-Csv-026160	Ciona savignyi	60.23	8.00e-122	430.00
IUUC-Cne-027002	Cryptococcus neoformans	40.27	2.00e-76	280.00
IUUC-Cme-027285	Cyanidioschyzon merolae	36.24	6.00e-51	195.00
IUUC-Dre-027999	Danio rerio	93.06	0.00e+00	634.00
IUUC-Dno-029250	Dasypus novemcinctus	99.41	0.00e+00	702.00
IUUC-Dor-030718	Dipodomys ordii	94.97	0.00e+00	665.00
IUUC-Dse-031498	Dothistroma septosporum	34.76	2.00e-27	117.00
IUUC-Dme-031969	Drosophila melanogaster	63.48	2.00e-142	499.00
IUUC-Ete-032592	Echinops telfairi	96.92	3.00e-31	129.00
IUUC-Eca-033258	Equus caballus	99.70	0.00e+00	703.00
IUUC-Fca-035980	Felis catus	99.40	0.00e+00	699.00
IUUC-Fal-037554	Ficedula albicollis	68.51	7.00e-99	353.00
IUUC-Fox-037902	Fusarium oxysporum	30.96	1.00e-51	197.00
IUUC-Fso-038418	Fusarium solani	30.71	4.00e-48	186.00
IUUC-Gmo-039288	Gadus morhua	90.55	2.00e-180	625.00
IUUC-Ggr-040076	Gaeumannomyces graminis	31.68	3.00e-50	193.00
IUUC-Gga-040347	Gallus gallus	92.31	3.00e-75	273.00
IUUC-Gac-042347	Gasterosteus aculeatus	92.43	3.00e-180	625.00
IUUC-Gma-044123	Glycine max	44.06	5.00e-75	275.00
IUUC-Ggo-044858	Gorilla gorilla	99.70	0.00e+00	702.00
IUUC-Hsa-046412	Homo sapiens	99.70	0.00e+00	704.00
IUUC-Hvu-047279	Hordeum vulgare	42.99	3.00e-69	255.00
IUUC-Itr-048924	Ictidomys tridecemlineatus	99.70	0.00e+00	699.00
IUUC-Kpa-049117	Komagataella pastoris	28.53	3.00e-31	129.00
IUUC-Lch-049533	Latimeria chalumnae	49.14	2.00e-73	270.00
IUUC-Lpe-051229	Leersia perrieri	32.38	6.00e-34	138.00
IUUC-Loc-052843	Lepisosteus oculatus	92.59	6.00e-121	426.00
IUUC-Lma-052997	Leptosphaeria maculans	33.07	9.00e-60	224.00
IUUC-Laf-053482	Loxodonta africana	99.70	0.00e+00	696.00
IUUC-Mcc-055075	Macaca mulatta	99.70	0.00e+00	704.00
IUUC-Meu-056683	Macropus eugenii	97.72	1.00e-150	526.00
IUUC-Mor-057082	Magnaporthe oryzae	31.18	2.00e-54	207.00
IUUC-Mpo-057573	Magnaporthe poae	31.00	5.00e-50	192.00
IUUC-Mtr-058601	Medicago truncatula	44.71	2.00e-79	289.00
IUUC-Mla-059168	Melampsora laricipopulina	40.67	4.00e-78	286.00
IUUC-Mga-059510	Meleagris gallopavo	98.80	6.00e-47	180.00
IUUC-Mvi-060515	Microbotryum violaceum	39.57	6.00e-66	245.00
IUUC-Mmr-060922	Microcebus murinus	99.70	0.00e+00	700.00
IUUC-Mdo-062491	Monodelphis domestica	98.52	0.00e+00	678.00
IUUC-Mmu-063770	Mus musculus	99.70	0.00e+00	699.00
IUUC-Mac-064789	Musa acuminata	41.93	2.00e-78	286.00
IUUC-Mlu-067918	Myotis lucifugus	97.43	0.00e+00	634.00
IUUC-Nfi-068389	Neosartorya fischeri	30.85	4.00e-55	209.00
IUUC-Ncr-068742	Neurospora crassa	32.08	6.00e-49	189.00
IUUC-Nle-069139	Nomascus leucogenys	99.70	0.00e+00	704.00
IUUC-Opr-070898	Ochotona princeps	98.12	2.00e-126	446.00
IUUC-Ont-071991	Oreochromis niloticus	91.08	0.00e+00	639.00
IUUC-Ocu-074065	Oryctolagus cuniculus	99.41	0.00e+00	699.00
IUUC-Oba-075221	Oryza barthii	41.49	3.00e-67	249.00
IUUC-Obr-076914	Oryza brachyantha	42.90	1.00e-63	236.00
IUUC-Ogu-078124	Oryza glumaepatula	41.49	3.00e-67	249.00
IUUC-Oin-080013	Oryza indica	39.82	1.00e-63	237.00
IUUC-Olo-080247	Oryza longistaminata	39.88	5.00e-60	225.00
IUUC-Ome-081769	Oryza meridionalis	42.09	8.00e-70	257.00
IUUC-Oni-082946	Oryza nivara	41.49	3.00e-67	249.00
IUUC-Opu-083268	Oryza punctata	36.13	2.00e-50	193.00
IUUC-Oru-085114	Oryza rufipogon	41.49	3.00e-67	249.00
IUUC-Osa-085829	Oryza sativa	42.09	5.00e-70	258.00
IUUC-Ola-087449	Oryzias latipes	92.70	1.00e-180	626.00
IUUC-Olu-087894	Ostreococcus lucimarinus	42.04	2.00e-73	268.00
IUUC-Oga-089036	Otolemur garnettii	99.70	0.00e+00	698.00
IUUC-Oar-089715	Ovis aries	99.70	0.00e+00	704.00
IUUC-Ptr-091000	Pan troglodytes	99.70	0.00e+00	697.00
IUUC-Pan-092187	Papio anubis	99.70	0.00e+00	704.00
IUUC-Psi-093377	Pelodiscus sinensis	97.04	1.00e-180	626.00
IUUC-Pma-094759	Petromyzon marinus	92.25	2.00e-79	289.00
IUUC-Pno-094883	Phaeosphaeria nodorum	32.62	7.00e-58	218.00
IUUC-Ppa-095684	Physcomitrella patens	44.51	5.00e-71	261.00
IUUC-Pfo-096861	Poecilia formosa	90.21	0.00e+00	632.00
IUUC-Pab-098030	Pongo abelii	99.70	0.00e+00	704.00
IUUC-Pop-099245	Populus trichocarpa	42.53	3.00e-80	292.00
IUUC-Pca-100191	Procavia capensis	95.91	0.00e+00	674.00
IUUC-Ppe-101829	Prunus persica	43.50	6.00e-79	288.00
IUUC-Pva-102689	Pteropus vampyrus	99.41	0.00e+00	704.00
IUUC-Pgr-103286	Puccinia graminis	37.85	4.00e-73	269.00
IUUC-Ptt-103919	Puccinia triticina	37.90	3.00e-72	265.00
IUUC-Pte-104372	Pyrenophora teres	33.50	8.00e-64	238.00
IUUC-Pyt-104456	Pyrenophora triticirepentis	33.25	1.00e-61	231.00
IUUC-Rno-105723	Rattus norvegicus	99.70	0.00e+00	697.00
IUUC-Sce-106348	Saccharomyces cerevisiae	26.25	6.00e-24	105.00
IUUC-Sha-107300	Sarcophilus harrisii	97.01	8.00e-154	536.00
IUUC-Sja-107685	Schizosaccharomyces japonicus	27.79	1.00e-38	154.00
IUUC-Spo-108308	Schizosaccharomyces pombe	30.03	2.00e-39	157.00
IUUC-Ssl-108558	Sclerotinia sclerotiorum	37.25	1.00e-23	105.00
IUUC-Smo-109123	Selaginella moellendorffii	46.69	1.00e-75	276.00
IUUC-Sit-110276	Setaria italica	42.99	3.00e-70	259.00
IUUC-Sly-111819	Solanum lycopersicum	44.82	8.00e-72	264.00
IUUC-Stu-112048	Solanum tuberosum	44.20	2.00e-75	276.00
IUUC-Sbi-114192	Sorghum bicolor	42.42	3.00e-68	252.00
IUUC-Sre-115212	Sporisorium reilianum	36.76	7.00e-63	235.00
IUUC-Ssc-116323	Sus scrofa	99.40	0.00e+00	695.00
IUUC-Tgu-117156	Taeniopygia guttata	94.81	2.00e-39	153.00
IUUC-Tru-118045	Takifugu rubripes	89.85	0.00e+00	634.00
IUUC-Tsy-118823	Tarsius syrichta	86.52	9.00e-160	555.00
IUUC-Tni-120106	Tetraodon nigroviridis	90.51	2.00e-129	456.00
IUUC-Tca-121462	Theobroma cacao	43.58	7.00e-80	291.00
IUUC-Tre-122204	Trichoderma reesei	38.41	2.00e-26	114.00
IUUC-Tvi-122550	Trichoderma virens	30.52	1.00e-49	191.00
IUUC-Tae-125239	Triticum aestivum	43.28	2.00e-71	263.00
IUUC-Tur-126538	Triticum urartu	38.54	1.00e-49	191.00
IUUC-Tme-127197	Tuber melanosporum	40.73	1.00e-67	251.00
IUUC-Tbe-127385	Tupaia belangeri	89.09	0.00e+00	632.00
IUUC-Ttr-128795	Tursiops truncatus	99.70	0.00e+00	702.00
IUUC-Uma-129401	Ustilago maydis	35.31	2.00e-52	201.00
IUUC-Vda-129968	Verticillium dahliae	28.31	3.00e-40	160.00
IUUC-Vvi-130944	Vitis vinifera	43.94	3.00e-79	289.00
IUUC-Xtr-131884	Xenopus tropicalis	94.05	0.00e+00	652.00
IUUC-Xma-133488	Xiphophorus maculatus	90.50	0.00e+00	637.00
IUUC-Yli-134552	Yarrowia lipolytica	25.35	9.00e-36	144.00
IUUC-Zma-135530	Zea mays	42.42	3.00e-68	252.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence