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Tag Content
iUUCD ID IUUC-Mcc-055862
Ensembl Protein ID ENSMMUP00000013649.3
UniProt Accession F7D386; F7D386_MACMU
Genbank Protein ID ENSMMUP00000013649
Protein Name Non-specific serine/threonine protein kinase
Genbank Nucleotide ID JSUE03001479
Gene Name PRKAA2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000010406.3 ENSMMUT00000014567.3 ENSMMUP00000013649.3
ENSMMUG00000010406.3 ENSMMUT00000056178.1 ENSMMUP00000048375.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 48.07 5.00e-124 442.00 IUUC-Ath-007014
UBD/Alpha-Helix/UBA 41.29 1.00e-106 381.00 IUUC-Spo-108202
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Macaca mulatta
Protein Sequence
(Fasta)
MAEKQKHDGR VKIGHYVLGD TLGVGTFGKV KIGEHQLTGH KVAVKILNRQ KIRSLDVVGK 60
IKREIQNLKL FRHPHIIKLY QVISTPTDFF MVMEYVSGGE LFDYICKHGR VEEMEARRLF 120
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Protein Fasta Sequence


>IUUC-Mcc-055862|UBD,UBA|Macaca mulatta
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Nucleotide Sequence
(Fasta)
CGGAGCGGAG CGGCAGGCGG CGAAGCGAGG CCGCGCGCGC GGAAGATGGC TGAGAAGCAG 60
AAGCACGACG GGCGGGTGAA GATCGGACAC TACGTGCTGG GCGACACGCT GGGCGTCGGC 120
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Nucleotide Fasta Sequence


>IUUC-Mcc-055862|UBD,UBA|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF16579--AdenylateSensor
PF00069--Pkinase
SMART

SM00220--S_TKc
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005794--C:Golgi apparatus
GO:0016607--C:nuclear speck
GO:0031588--C:nucleotide-activated protein kinase complex
GO:0005634--C:nucleus
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0035690--P:cellular response to drug
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0042593--P:glucose homeostasis
GO:0035404--P:histone-serine phosphorylation
GO:0035556--P:intracellular signal transduction
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0042752--P:regulation of circadian rhythm
GO:0010468--P:regulation of gene expression
GO:0016241--P:regulation of macroautophagy
GO:0014850--P:response to muscle activity
KEGG mcc:717703
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000713 Aegilops tauschii 47.73 3.00e-122 432.00
IUUC-Aml-001907 Ailuropoda melanoleuca 74.86 0.00e+00 797.00
IUUC-Atr-002770 Amborella trichopoda 47.77 8.00e-125 440.00
IUUC-Apl-003395 Anas platyrhynchos 93.49 0.00e+00 1021.00
IUUC-Aca-004480 Anolis carolinensis 93.92 0.00e+00 1029.00
IUUC-Aly-006289 Arabidopsis lyrata 47.96 3.00e-125 442.00
IUUC-Ath-007014 Arabidopsis thaliana 48.07 1.00e-125 443.00
IUUC-Ago-007957 Ashbya gossypii 42.62 1.00e-115 410.00
IUUC-Acl-008103 Aspergillus clavatus 60.07 4.00e-101 362.00
IUUC-Afl-008555 Aspergillus flavus 59.71 1.00e-101 364.00
IUUC-Afu-008949 Aspergillus fumigatus 60.07 2.00e-101 363.00
IUUC-Ani-009408 Aspergillus nidulans 62.17 1.00e-101 363.00
IUUC-Ang-009551 Aspergillus niger 60.07 4.00e-101 362.00
IUUC-Aor-010176 Aspergillus oryzae 59.71 1.00e-101 364.00
IUUC-Ate-010287 Aspergillus terreus 60.07 6.00e-101 362.00
IUUC-Ame-011019 Astyanax mexicanus 86.27 0.00e+00 1011.00
IUUC-Bgr-012045 Blumeria graminis 61.80 3.00e-102 366.00
IUUC-Bta-012786 Bos taurus 75.95 0.00e+00 798.00
IUUC-Bci-013774 Botrytis cinerea 46.84 1.00e-104 374.00
IUUC-Bdi-014319 Brachypodium distachyon 46.94 8.00e-125 440.00
IUUC-Bol-016242 Brassica oleracea 48.25 4.00e-128 451.00
IUUC-Bra-016750 Brassica rapa 48.25 2.00e-128 452.00
IUUC-Cel-018518 Caenorhabditis elegans 58.09 0.00e+00 628.00
IUUC-Cja-019386 Callithrix jacchus 99.64 0.00e+00 1110.00
IUUC-Cfa-020177 Canis familiaris 73.47 0.00e+00 764.00
IUUC-Cpo-021805 Cavia porcellus 99.09 0.00e+00 1104.00
IUUC-Cre-022915 Chlamydomonas reinhardtii 54.83 1.00e-96 345.00
IUUC-Csa-024267 Chlorocebus sabaeus 99.82 0.00e+00 1095.00
IUUC-Cho-024859 Choloepus hoffmanni 71.69 0.00e+00 751.00
IUUC-Cin-025550 Ciona intestinalis 62.16 0.00e+00 677.00
IUUC-Csv-026139 Ciona savignyi 60.33 0.00e+00 676.00
IUUC-Cne-027044 Cryptococcus neoformans 51.15 2.00e-108 386.00
IUUC-Cme-027289 Cyanidioschyzon merolae 45.57 2.00e-111 395.00
IUUC-Dre-027749 Danio rerio 70.54 0.00e+00 796.00
IUUC-Dno-030006 Dasypus novemcinctus 74.68 0.00e+00 796.00
IUUC-Dor-030578 Dipodomys ordii 98.55 0.00e+00 1103.00
IUUC-Dse-031507 Dothistroma septosporum 62.69 9.00e-105 374.00
IUUC-Dme-031704 Drosophila melanogaster 60.41 0.00e+00 665.00
IUUC-Ete-033055 Echinops telfairi 73.16 0.00e+00 813.00
IUUC-Eca-034016 Equus caballus 98.08 0.00e+00 1032.00
IUUC-Fca-035754 Felis catus 73.02 0.00e+00 790.00
IUUC-Fal-037363 Ficedula albicollis 74.77 0.00e+00 790.00
IUUC-Fox-038073 Fusarium oxysporum 51.62 1.00e-105 377.00
IUUC-Fso-038236 Fusarium solani 51.24 6.00e-102 365.00
IUUC-Gmo-039633 Gadus morhua 70.33 0.00e+00 819.00
IUUC-Ggr-039987 Gaeumannomyces graminis 48.77 6.00e-102 365.00
IUUC-Gga-040546 Gallus gallus 92.04 0.00e+00 1056.00
IUUC-Gac-041822 Gasterosteus aculeatus 83.99 0.00e+00 950.00
IUUC-Gma-042712 Glycine max 47.07 4.00e-125 441.00
IUUC-Ggo-045303 Gorilla gorilla 100.00 0.00e+00 1115.00
IUUC-Hsa-045746 Homo sapiens 100.00 0.00e+00 1115.00
IUUC-Hvu-047406 Hordeum vulgare 47.65 3.00e-125 441.00
IUUC-Itr-048134 Ictidomys tridecemlineatus 99.46 0.00e+00 1111.00
IUUC-Kpa-049190 Komagataella pastoris 44.86 4.00e-122 431.00
IUUC-Lch-049623 Latimeria chalumnae 73.05 0.00e+00 784.00
IUUC-Lpe-051392 Leersia perrieri 46.94 8.00e-125 440.00
IUUC-Loc-052928 Lepisosteus oculatus 90.24 0.00e+00 1033.00
IUUC-Lma-053054 Leptosphaeria maculans 62.92 3.00e-106 379.00
IUUC-Laf-053459 Loxodonta africana 98.37 0.00e+00 1101.00
IUUC-Mor-057170 Magnaporthe oryzae 50.44 3.00e-100 359.00
IUUC-Mpo-057302 Magnaporthe poae 49.18 3.00e-102 366.00
IUUC-Mtr-058309 Medicago truncatula 48.12 1.00e-123 436.00
IUUC-Mla-059058 Melampsora laricipopulina 43.09 2.00e-104 373.00
IUUC-Mga-059206 Meleagris gallopavo 91.55 0.00e+00 996.00
IUUC-Mvi-060337 Microbotryum violaceum 42.03 1.00e-108 387.00
IUUC-Mmr-061619 Microcebus murinus 98.37 0.00e+00 1090.00
IUUC-Mdo-062160 Monodelphis domestica 93.66 0.00e+00 1072.00
IUUC-Mmu-063406 Mus musculus 97.83 0.00e+00 1090.00
IUUC-Mac-064518 Musa acuminata 45.54 2.00e-121 429.00
IUUC-Mpu-066326 Mustela putorius furo 99.04 0.00e+00 1043.00
IUUC-Mlu-067968 Myotis lucifugus 97.16 0.00e+00 1006.00
IUUC-Nfi-068493 Neosartorya fischeri 60.07 2.00e-101 363.00
IUUC-Ncr-068665 Neurospora crassa 40.51 1.00e-106 380.00
IUUC-Nle-070158 Nomascus leucogenys 99.82 0.00e+00 1113.00
IUUC-Opr-070272 Ochotona princeps 72.84 0.00e+00 788.00
IUUC-Ont-071395 Oreochromis niloticus 86.20 0.00e+00 993.00
IUUC-Oan-073322 Ornithorhynchus anatinus 68.96 0.00e+00 751.00
IUUC-Ocu-074188 Oryctolagus cuniculus 73.59 0.00e+00 790.00
IUUC-Oba-075436 Oryza barthii 47.44 2.00e-126 446.00
IUUC-Obr-076507 Oryza brachyantha 47.57 3.00e-126 445.00
IUUC-Ogl-077718 Oryza glaberrima 50.34 9.00e-124 437.00
IUUC-Ogu-078349 Oryza glumaepatula 47.11 1.00e-126 446.00
IUUC-Oin-079889 Oryza indica 46.00 3.00e-124 438.00
IUUC-Olo-080521 Oryza longistaminata 47.44 2.00e-126 446.00
IUUC-Ome-081630 Oryza meridionalis 47.24 4.00e-126 444.00
IUUC-Oni-082211 Oryza nivara 47.44 8.00e-127 447.00
IUUC-Opu-083617 Oryza punctata 47.14 4.00e-125 441.00
IUUC-Oru-084252 Oryza rufipogon 47.44 1.00e-126 446.00
IUUC-Osa-085548 Oryza sativa 47.44 1.00e-126 446.00
IUUC-Ola-087169 Oryzias latipes 84.41 0.00e+00 967.00
IUUC-Olu-087861 Ostreococcus lucimarinus 48.48 4.00e-116 411.00
IUUC-Oga-088003 Otolemur garnettii 74.86 0.00e+00 797.00
IUUC-Oar-089933 Ovis aries 75.95 0.00e+00 798.00
IUUC-Ptr-090741 Pan troglodytes 100.00 0.00e+00 1115.00
IUUC-Pan-092526 Papio anubis 75.05 0.00e+00 799.00
IUUC-Psi-094034 Pelodiscus sinensis 74.37 0.00e+00 787.00
IUUC-Pno-095030 Phaeosphaeria nodorum 62.92 2.00e-104 372.00
IUUC-Ppa-095615 Physcomitrella patens 45.28 7.00e-124 437.00
IUUC-Pfo-096295 Poecilia formosa 85.30 0.00e+00 980.00
IUUC-Pab-098023 Pongo abelii 100.00 0.00e+00 1115.00
IUUC-Pop-100042 Populus trichocarpa 47.98 4.00e-128 451.00
IUUC-Pca-101104 Procavia capensis 79.12 2.00e-175 608.00
IUUC-Ppe-101642 Prunus persica 48.95 2.00e-125 442.00
IUUC-Pva-102470 Pteropus vampyrus 98.19 0.00e+00 1092.00
IUUC-Pgr-103406 Puccinia graminis 61.36 5.00e-92 332.00
IUUC-Ptt-103713 Puccinia triticina 37.85 5.00e-79 288.00
IUUC-Pte-104259 Pyrenophora teres 62.55 2.00e-105 376.00
IUUC-Pyt-104752 Pyrenophora triticirepentis 62.92 7.00e-106 378.00
IUUC-Rno-104960 Rattus norvegicus 98.37 0.00e+00 1102.00
IUUC-Sce-106290 Saccharomyces cerevisiae 42.46 2.00e-116 413.00
IUUC-Sha-107603 Sarcophilus harrisii 74.68 0.00e+00 794.00
IUUC-Sja-107772 Schizosaccharomyces japonicus 40.53 2.00e-110 393.00
IUUC-Spo-108202 Schizosaccharomyces pombe 41.29 5.00e-107 381.00
IUUC-Ssl-108535 Sclerotinia sclerotiorum 46.34 2.00e-103 370.00
IUUC-Smo-109309 Selaginella moellendorffii 45.44 6.00e-122 431.00
IUUC-Sit-109745 Setaria italica 48.38 5.00e-127 447.00
IUUC-Sly-110890 Solanum lycopersicum 48.28 1.00e-126 446.00
IUUC-Stu-112144 Solanum tuberosum 46.23 6.00e-119 421.00
IUUC-Sar-113521 Sorex araneus 65.33 0.00e+00 638.00
IUUC-Sbi-114764 Sorghum bicolor 47.99 7.00e-128 450.00
IUUC-Sre-115141 Sporisorium reilianum 66.91 2.00e-115 410.00
IUUC-Ssc-115732 Sus scrofa 73.61 0.00e+00 763.00
IUUC-Tgu-117190 Taeniopygia guttata 74.95 0.00e+00 788.00
IUUC-Tru-118735 Takifugu rubripes 84.59 0.00e+00 979.00
IUUC-Tsy-119503 Tarsius syrichta 95.96 0.00e+00 988.00
IUUC-Tni-119880 Tetraodon nigroviridis 84.79 0.00e+00 979.00
IUUC-Tca-121386 Theobroma cacao 47.46 4.00e-127 448.00
IUUC-Tre-122070 Trichoderma reesei 50.00 2.00e-103 369.00
IUUC-Tvi-122305 Trichoderma virens 49.46 4.00e-102 365.00
IUUC-Tae-123515 Triticum aestivum 47.75 3.00e-126 445.00
IUUC-Tur-126416 Triticum urartu 47.55 1.00e-123 436.00
IUUC-Tme-127174 Tuber melanosporum 40.30 7.00e-67 248.00
IUUC-Tbe-127791 Tupaia belangeri 86.09 2.00e-113 402.00
IUUC-Ttr-129224 Tursiops truncatus 73.02 0.00e+00 788.00
IUUC-Uma-129372 Ustilago maydis 66.91 1.00e-114 407.00
IUUC-Vda-129819 Verticillium dahliae 53.68 3.00e-86 313.00
IUUC-Vpa-130220 Vicugna pacos 98.27 0.00e+00 1030.00
IUUC-Vvi-131649 Vitis vinifera 47.97 8.00e-126 443.00
IUUC-Xtr-132954 Xenopus tropicalis 92.41 0.00e+00 1066.00
IUUC-Xma-134119 Xiphophorus maculatus 85.13 0.00e+00 978.00
IUUC-Yli-134422 Yarrowia lipolytica 45.58 1.00e-119 423.00
IUUC-Zma-135621 Zea mays 62.31 2.00e-120 426.00
Created Date 25-Jun-2017

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