iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028322

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

F-box and WD repeat domain-containing 11a; F-box and WD-40 domain protein 11b

Genbank Nucleotide ID

BC045356

Gene Name

fbxw11a; fbxw11; fbxw11b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000104806.1	ENSDART00000167293.1	ENSDARP00000139358.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-56	187.0	426	460
UBD/Beta-Prp	2.70e-68	231.3	337	504

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ v+c++f d +++vsG++Dg+ikvWDl    +
   Q: 426  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLQAALD 460
           8**********.44****************977665 PP

UBD/Beta-Prp

   S: 41   tgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           + +l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl
   Q: 337  DISLRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACL 421
           556667789*************9..8**************************************..*********************** PP
   S: 130  eetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           + +l+gh+++v+c++++   + +vsG++D+++++Wdl         ++  +lrtl + h ++v  l+fd+  ++++s s+d t+ +wd+
   Q: 422  R-VLEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLqaaldprapASTLCLRTLVE-HSGRVFRLQFDE--FQIISSSHDDTILIWDF 504
           *.***************9..***********************************99.************..99**************7 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MDPDKEDKTL ELMNMTGMES QINTDEVSPK KTTVFKLGNG SLAGSRKRPS QGSFDKEKDL 60
CIQLFDQWSE SDQVEFVEHL IARMCHYQHG HINSYLKPML QRDFITALPA RGLDHIAENI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTCCATCT TTTGTAGCTG TGTGTTGTTT CGCTCTTCTC TCGGGTTCAC CGACGGGTTT 60
CCATTTTCAC GGTTGGATTC AGCTAGAACA ACAATAATAT GGATCCGGAC AAGGAGGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0002040--P:sprouting angiogenesis

KEGG

dre:334373

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008355	Aspergillus clavatus	28.57	3.00e-46	180.00
IUUC-Afu-008790	Aspergillus fumigatus	29.88	3.00e-37	150.00
IUUC-Aor-010185	Aspergillus oryzae	26.77	1.00e-46	181.00
IUUC-Cin-025188	Ciona intestinalis	78.95	0.00e+00	801.00
IUUC-Csv-026020	Ciona savignyi	74.90	0.00e+00	765.00
IUUC-Ete-032978	Echinops telfairi	70.34	0.00e+00	694.00
IUUC-Ola-086985	Oryzias latipes	85.59	0.00e+00	999.00
IUUC-Pfo-096783	Poecilia formosa	85.94	0.00e+00	1001.00
IUUC-Ptt-103853	Puccinia triticina	31.77	5.00e-61	228.00
IUUC-Sja-107743	Schizosaccharomyces japonicus	35.89	6.00e-76	278.00
IUUC-Spo-108200	Schizosaccharomyces pombe	31.03	4.00e-65	242.00
IUUC-Tru-117671	Takifugu rubripes	86.30	0.00e+00	1000.00
IUUC-Tni-120359	Tetraodon nigroviridis	92.03	0.00e+00	1011.00
IUUC-Vda-129941	Verticillium dahliae	31.96	8.00e-56	212.00
IUUC-Yli-134582	Yarrowia lipolytica	34.99	2.00e-56	213.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence