iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gma-044098

UUCD1 version

UUC-GlM-03020

Ensembl Protein ID

GLYMA12G00510.1

UniProt Accession

C6TL41; C6TL41_SOYBN

Genbank Protein ID

ACU23631.1; KRH23773.1

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

BT098417; CM000845

Gene Name

100786346; GLYMA_12G002900

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GLYMA12G00510	GLYMA12G00510.1	GLYMA12G00510.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-24	85.3	50	87
UBD/Beta-Prp	6.80e-53	181.4	7	254

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v+ ++   d  +l++Gs D t k+WD+ +g +l
   Q: 50   GHNGAVWTCDVsRDsARLITGSADQTAKLWDVQSGLQL 87
           89********9977799****************99887 PP

UBD/Beta-Prp

   S: 49   sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee........... 131
           +ghe + t +k+++dg++l ++++D++  vw  ++g+ + t++gh+  v+++++s+++ +l++Gs+d+t+++wd+++g  l++           
   Q: 7    KGHERPLTFLKYNRDGDLLFSCAKDHNPTVWFADNGERLGTYRGHNGAVWTCDVSRDSARLITGSADQTAKLWDVQSGLQLYTfnfdsparsvd 100
           5666666666666666666666666666666666666666666666666666666666666666666666666666666666666666666666 PP
   S: 132  ........................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsv 183
                                                   + +g +g +n + + p +  ++s++ D ++r+Wd++tgkll++   ++gh++ v
   Q: 101  fsvgdklavittdpfmelpsaihvkriandpsqqigesvlLIKGPQGRINRAIWGPLNTTIISAGEDAVIRIWDSETGKLLQESdkESGHKKTV 194
           66666666666666666666666666666799999***9999999***************************************99777***** PP
   S: 184  yslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght..dnvksvrfspnderlvsgssD 243
           +sl+ + +  ++++gsld++ +lwd ++ + ++t+   +  + v++  ++  d+ ++ g++D
   Q: 195  TSLAKSADDSHFLTGSLDKSARLWDTRSLTLIKTYVTERpvNAVTMSPLL--DHVVIGGGQD 254
           **********************************9976544555555555..5555555555 PP

Organism

Glycine max

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLKYNR DGDLLFSCAK DHNPTVWFAD NGERLGTYRG HNGAVWTCDV 60
SRDSARLITG SADQTAKLWD VQSGLQLYTF NFDSPARSVD FSVGDKLAVI TTDPFMELPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTAAATTA AAATATTAAT AAGCGAAGAA TAGTGAACCC TAAGTGAGGA TACACTATAC 60
TCCGGTAGCC GCTGTGTTGG TGAGTGAGTT GTGGTGCTTT TGAAAGATGA GGCCGATTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

KEGG

gmx:100819486

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afu-009080	Aspergillus fumigatus	43.81	1.00e-76	279.00
IUUC-Nfi-068478	Neosartorya fischeri	43.81	2.00e-77	281.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence