iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068961

Ensembl Protein ID

EAA28640

UniProt Accession

Q7S020; Q7S020_NEUCR

Genbank Protein ID

EAA28640.3

Protein Name

Ubiquitin C-terminal hydrolase

Genbank Nucleotide ID

CM002236

Gene Name

NCU08579

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU08579	EAA28640	EAA28640

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.60e-50	169.7	52	615

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp.....................................kepkgellkslqklfeelw..k 62
           +Gl N  N C++NSvLQ+L+ + +lr +l +++++++ +                                          + g ++k l++++ +l    
   Q: 52   VGLINPANDCFINSVLQALAGLGDLRLYLIRETHRRCLDGGWvyaqtipsdvwgsggegegdetskwqvrggvpewkaeGLQMGIVTKGLKDILDALNerP 152
           6******************************777777766557788888888888888888888877777888777776666679************9777 PP
   S: 63   skkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk..........eknkpkeeeeeedkselsde........................ 129
             kk +s + ++++l+ +  +  + +qqDaqEfl+++ ++l +e +            +++p+++           +                        
   Q: 153  IYKKTISASPFVRTLEIAFGQRISRQQQDAQEFLQVVAERLCDEYHAgqrarsyamrGAEQPTTKI----------Slnsktsdsealdrplplraseqvs 243
           77899*************999899*********************775555555544222222222..........133345555678999********** PP
   S: 130  ..............aeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck... 212
                         +  ++++ ++      F+g+++sqi cl+c+ +   ++++f++l+l+vp   +t   +l+ c++ ++k+e +e+   ++cekc+   
   Q: 244  gadqpaataasavpNGADEERAEEG---FPFEGSFESQIECLTCGFRPrPTQSTFCTLTLNVPHIPTT---TLSACFDGMFKTEYIED---FKCEKCRllh 335
           *******997755444444444444...47****************999**************99988...****************7...********** PP
   S: 213  ...................................................kkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
                                                               k++  + ++++ +P++L +hL+R  ++ + ++++k+  kv+fp+ L l 
   Q: 336  akavleadiqrstsessrekartalaslelaietdpekapkgvelpdpryaPKRKIARHIRMTGFPRILAIHLSRSIYDMS-NFSQKNLAKVTFPELLPLG 435
           *****************99999999999999999999999999999999998888***********************998.7777*********99**99 PP
   S: 263  pfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.............................................................. 301
             +++        +kY+L++vv H+G+++sGHY ++ ++                                                              
   Q: 436  GLLQQ--------RKYKLLGVVTHKGNHHSGHYESFRRQniyppfsnpgtfqpsgayiytsspsninpgqaiqpgsgqaptpgveggitpaneprststsr 528
           66665........89************************************************************************************** PP
   S: 302  .....................................................ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
                                                                ++ +W++++D+kV+e +  +vl ++ ++ Y+lfY+
   Q: 529  erdtdtnslrsaaasarstlikiaskpssragspditgskphtktpvkskrhkSSSRWWRISDDKVKEASTRDVLGMQ-REVYLLFYE 615
           **********************************99999999999998876544555*******************65.********8 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MPDKTLTVAA YAAGASLAAI TLIYVFGPTY FLDNDPSANS TSVFSIKRNG AVGLINPAND 60
CFINSVLQAL AGLGDLRLYL IRETHRRCLD GGWVYAQTIP SDVWGSGGEG EGDETSKWQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTATCCTGC TCTATGAACA GTTTAAGCCG ATCTGGGCGT TAGGGTGGGA AATTTTGGGA 60
CCTGGCACGC CTGGATAGAC TAGCCCCACC CAGGCCGGTC ACGACTTCTT ACTGTATAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ncr:NCU08579

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007955	Ashbya gossypii	25.39	9.00e-18	83.60
IUUC-Acl-008228	Aspergillus clavatus	50.29	6.00e-122	429.00
IUUC-Afl-008530	Aspergillus flavus	49.38	2.00e-118	418.00
IUUC-Afu-008943	Aspergillus fumigatus	45.19	1.00e-133	468.00
IUUC-Ang-009829	Aspergillus niger	44.50	3.00e-125	440.00
IUUC-Aor-009934	Aspergillus oryzae	50.66	7.00e-118	416.00
IUUC-Ate-010439	Aspergillus terreus	52.49	2.00e-120	424.00
IUUC-Bgr-012072	Blumeria graminis	49.71	9.00e-124	435.00
IUUC-Bci-013641	Botrytis cinerea	59.16	1.00e-148	518.00
IUUC-Cgl-026463	Colletotrichum gloeosporioides	48.56	1.00e-149	521.00
IUUC-Dse-031517	Dothistroma septosporum	52.33	8.00e-118	415.00
IUUC-Fox-037837	Fusarium oxysporum	49.77	5.00e-157	546.00
IUUC-Fso-038234	Fusarium solani	50.00	2.00e-154	537.00
IUUC-Ggr-039945	Gaeumannomyces graminis	57.28	1.00e-145	508.00
IUUC-Lma-053197	Leptosphaeria maculans	45.88	5.00e-112	396.00
IUUC-Mor-057061	Magnaporthe oryzae	62.29	6.00e-147	512.00
IUUC-Mpo-057549	Magnaporthe poae	67.31	4.00e-76	277.00
IUUC-Nfi-068557	Neosartorya fischeri	43.86	4.00e-132	463.00
IUUC-Pno-094802	Phaeosphaeria nodorum	55.17	1.00e-132	464.00
IUUC-Pte-104416	Pyrenophora teres	48.93	2.00e-146	510.00
IUUC-Pyt-104503	Pyrenophora triticirepentis	47.90	9.00e-148	515.00
IUUC-Tre-121937	Trichoderma reesei	49.32	2.00e-151	527.00
IUUC-Tvi-122428	Trichoderma virens	50.97	2.00e-149	520.00
IUUC-Tme-126993	Tuber melanosporum	44.25	1.00e-90	325.00
IUUC-Vda-129757	Verticillium dahliae	47.53	7.00e-145	505.00
IUUC-Yli-134426	Yarrowia lipolytica	32.52	5.00e-33	134.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence