iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117590

Ensembl Protein ID

ENSTRUP00000025493.1

UniProt Accession

H2TLD8; H2TLD8_TAKRU

Protein Name

Protein HIRA

Gene Name

hira

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000010121.1	ENSTRUT00000025596.1	ENSTRUP00000025493.1
ENSTRUG00000010121.1	ENSTRUT00000025597.1	ENSTRUP00000025494.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.90e-19	68.6	69	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H + v+c+++ ++  +l+sG+dD+ ++vW 
   Q: 69   HLACVNCVRWsNNgLYLASGGDDKLVMVWK 98
           8899******977799*************7 PP

Organism

Takifugu rubripes

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MKLLKPSWVS HNGKPIFSVD IHPDGTKFAT GGQGEDSGKV MIWNMAPVLK EEDEKNENVP 60
KMLCQMDNHL ACVNCVRWSN NGLYLASGGD DKLVMVWKRA ALIGPSTVFG SSNKLANVEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGCTGC TGAAGCCGAG CTGGGTGAGC CACAACGGTA AGCTTGTGCA GGAATCTGGG 60
GGACCAAGTT GGTCTTTTGT TGTCGGAGGG GGTGAATTGA ACAGGCGTGC TGTGGTGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	35.27	1.00e-87	318.00
IUUC-Aml-001723	Ailuropoda melanoleuca	66.05	0.00e+00	1242.00
IUUC-Atr-003132	Amborella trichopoda	36.20	2.00e-91	330.00
IUUC-Apl-003197	Anas platyrhynchos	67.92	0.00e+00	1313.00
IUUC-Aca-004733	Anolis carolinensis	65.77	0.00e+00	1314.00
IUUC-Aly-005446	Arabidopsis lyrata	35.73	9.00e-83	301.00
IUUC-Ath-007627	Arabidopsis thaliana	36.80	9.00e-86	311.00
IUUC-Ago-007766	Ashbya gossypii	32.35	2.00e-58	221.00
IUUC-Acl-008104	Aspergillus clavatus	32.23	6.00e-62	233.00
IUUC-Afl-008591	Aspergillus flavus	32.45	2.00e-61	231.00
IUUC-Afu-008781	Aspergillus fumigatus	33.06	7.00e-57	216.00
IUUC-Ani-009272	Aspergillus nidulans	31.37	3.00e-53	203.00
IUUC-Ang-009655	Aspergillus niger	29.31	1.00e-63	238.00
IUUC-Aor-010119	Aspergillus oryzae	32.45	2.00e-61	231.00
IUUC-Ate-010530	Aspergillus terreus	28.81	1.00e-52	202.00
IUUC-Ame-011147	Astyanax mexicanus	92.08	3.00e-55	205.00
IUUC-Bgr-012237	Blumeria graminis	32.58	3.00e-61	230.00
IUUC-Bta-013320	Bos taurus	66.12	0.00e+00	1285.00
IUUC-Bci-013795	Botrytis cinerea	30.15	5.00e-68	253.00
IUUC-Bdi-014075	Brachypodium distachyon	36.90	7.00e-91	328.00
IUUC-Bol-016440	Brassica oleracea	36.09	6.00e-88	318.00
IUUC-Bra-016651	Brassica rapa	35.84	6.00e-88	319.00
IUUC-Cel-018692	Caenorhabditis elegans	38.10	4.00e-76	280.00
IUUC-Cja-018987	Callithrix jacchus	65.37	0.00e+00	1179.00
IUUC-Cfa-020132	Canis familiaris	65.58	0.00e+00	1244.00
IUUC-Cpo-021484	Cavia porcellus	66.09	0.00e+00	1274.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	34.29	1.00e-59	224.00
IUUC-Csa-023081	Chlorocebus sabaeus	65.90	0.00e+00	1268.00
IUUC-Cin-025182	Ciona intestinalis	55.91	4.00e-158	552.00
IUUC-Csv-026154	Ciona savignyi	57.17	4.00e-158	552.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	29.06	1.00e-64	241.00
IUUC-Cne-026891	Cryptococcus neoformans	39.46	2.00e-81	297.00
IUUC-Cme-027349	Cyanidioschyzon merolae	29.63	4.00e-52	200.00
IUUC-Dre-027655	Danio rerio	77.39	0.00e+00	1504.00
IUUC-Dno-029557	Dasypus novemcinctus	60.78	0.00e+00	792.00
IUUC-Dor-030687	Dipodomys ordii	69.20	0.00e+00	651.00
IUUC-Dse-031334	Dothistroma septosporum	30.95	2.00e-62	234.00
IUUC-Dme-031746	Drosophila melanogaster	52.80	1.00e-156	547.00
IUUC-Ete-032384	Echinops telfairi	62.10	0.00e+00	1164.00
IUUC-Eca-033430	Equus caballus	65.96	0.00e+00	1243.00
IUUC-Fca-036121	Felis catus	65.87	0.00e+00	1248.00
IUUC-Fal-036817	Ficedula albicollis	67.67	0.00e+00	1313.00
IUUC-Fox-037906	Fusarium oxysporum	29.75	2.00e-65	243.00
IUUC-Fso-038409	Fusarium solani	29.49	2.00e-64	241.00
IUUC-Gmo-039151	Gadus morhua	73.86	0.00e+00	1474.00
IUUC-Ggr-040016	Gaeumannomyces graminis	33.33	5.00e-68	253.00
IUUC-Gga-040936	Gallus gallus	68.30	0.00e+00	1357.00
IUUC-Gac-041405	Gasterosteus aculeatus	80.12	0.00e+00	1539.00
IUUC-Gma-044252	Glycine max	35.54	3.00e-89	323.00
IUUC-Ggo-045430	Gorilla gorilla	66.22	0.00e+00	1265.00
IUUC-Hsa-046442	Homo sapiens	66.51	0.00e+00	1274.00
IUUC-Hvu-047587	Hordeum vulgare	35.45	7.00e-78	285.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	87.33	4.00e-159	553.00
IUUC-Kpa-049145	Komagataella pastoris	31.38	3.00e-60	227.00
IUUC-Lch-050474	Latimeria chalumnae	82.72	0.00e+00	804.00
IUUC-Lpe-051209	Leersia perrieri	35.44	3.00e-85	310.00
IUUC-Loc-052119	Lepisosteus oculatus	74.06	0.00e+00	1410.00
IUUC-Lma-053237	Leptosphaeria maculans	31.30	5.00e-66	246.00
IUUC-Laf-053718	Loxodonta africana	66.06	0.00e+00	1271.00
IUUC-Mcc-055621	Macaca mulatta	64.97	0.00e+00	1185.00
IUUC-Meu-055914	Macropus eugenii	58.50	0.00e+00	1102.00
IUUC-Mor-057090	Magnaporthe oryzae	32.94	2.00e-65	244.00
IUUC-Mpo-057364	Magnaporthe poae	30.91	8.00e-70	258.00
IUUC-Mtr-057744	Medicago truncatula	36.15	6.00e-90	325.00
IUUC-Mla-058914	Melampsora laricipopulina	36.51	2.00e-86	313.00
IUUC-Mga-060181	Meleagris gallopavo	67.28	0.00e+00	1320.00
IUUC-Mvi-060432	Microbotryum violaceum	36.96	3.00e-75	276.00
IUUC-Mmr-060871	Microcebus murinus	66.38	0.00e+00	1291.00
IUUC-Mdo-062301	Monodelphis domestica	65.73	0.00e+00	1285.00
IUUC-Mmu-063888	Mus musculus	66.51	0.00e+00	1283.00
IUUC-Mac-065137	Musa acuminata	38.25	4.00e-90	326.00
IUUC-Mpu-066732	Mustela putorius furo	66.21	0.00e+00	1256.00
IUUC-Mlu-067542	Myotis lucifugus	65.03	0.00e+00	1248.00
IUUC-Nfi-068396	Neosartorya fischeri	33.80	1.00e-56	214.00
IUUC-Ncr-068842	Neurospora crassa	31.38	1.00e-67	251.00
IUUC-Nle-070156	Nomascus leucogenys	66.09	0.00e+00	1271.00
IUUC-Opr-070808	Ochotona princeps	61.96	0.00e+00	962.00
IUUC-Ont-072105	Oreochromis niloticus	87.80	0.00e+00	1809.00
IUUC-Ocu-074962	Oryctolagus cuniculus	65.30	0.00e+00	1253.00
IUUC-Oba-075178	Oryza barthii	35.54	5.00e-91	329.00
IUUC-Obr-076399	Oryza brachyantha	37.13	2.00e-91	330.00
IUUC-Ogu-078797	Oryza glumaepatula	35.54	5.00e-91	329.00
IUUC-Oin-080085	Oryza indica	34.23	1.00e-77	284.00
IUUC-Olo-081048	Oryza longistaminata	39.74	5.00e-64	240.00
IUUC-Ome-081324	Oryza meridionalis	35.54	4.00e-91	329.00
IUUC-Oni-082548	Oryza nivara	35.54	5.00e-91	329.00
IUUC-Opu-084008	Oryza punctata	41.07	4.00e-89	322.00
IUUC-Oru-084339	Oryza rufipogon	35.36	1.00e-90	327.00
IUUC-Osa-085782	Oryza sativa	35.36	1.00e-90	327.00
IUUC-Ola-087302	Oryzias latipes	81.35	0.00e+00	1553.00
IUUC-Olu-087611	Ostreococcus lucimarinus	35.63	4.00e-89	322.00
IUUC-Oga-087935	Otolemur garnettii	65.58	0.00e+00	1247.00
IUUC-Oar-089229	Ovis aries	62.24	0.00e+00	725.00
IUUC-Ptr-090715	Pan troglodytes	66.41	0.00e+00	1273.00
IUUC-Pan-092318	Papio anubis	65.67	0.00e+00	1241.00
IUUC-Psi-094053	Pelodiscus sinensis	66.83	0.00e+00	1299.00
IUUC-Pno-094985	Phaeosphaeria nodorum	31.46	8.00e-57	215.00
IUUC-Ppa-095819	Physcomitrella patens	34.40	9.00e-85	308.00
IUUC-Pfo-096857	Poecilia formosa	84.53	0.00e+00	1699.00
IUUC-Pab-098047	Pongo abelii	66.16	0.00e+00	1272.00
IUUC-Pop-099587	Populus trichocarpa	41.84	8.00e-88	318.00
IUUC-Pca-100558	Procavia capensis	57.74	8.00e-122	431.00
IUUC-Ppe-101261	Prunus persica	36.71	3.00e-89	323.00
IUUC-Pva-102683	Pteropus vampyrus	66.57	0.00e+00	1296.00
IUUC-Pgr-103660	Puccinia graminis	39.35	8.00e-77	281.00
IUUC-Ptt-103900	Puccinia triticina	40.43	2.00e-78	286.00
IUUC-Pte-104209	Pyrenophora teres	31.42	4.00e-63	236.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	31.56	1.00e-62	235.00
IUUC-Rno-105566	Rattus norvegicus	66.32	0.00e+00	1285.00
IUUC-Sce-106291	Saccharomyces cerevisiae	32.35	3.00e-61	230.00
IUUC-Sha-107514	Sarcophilus harrisii	62.61	0.00e+00	1165.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	40.43	2.00e-78	287.00
IUUC-Spo-108162	Schizosaccharomyces pombe	38.89	2.00e-76	280.00
IUUC-Smo-109186	Selaginella moellendorffii	40.85	8.00e-89	322.00
IUUC-Sit-110730	Setaria italica	37.23	3.00e-90	327.00
IUUC-Sly-111547	Solanum lycopersicum	37.07	2.00e-89	324.00
IUUC-Stu-112705	Solanum tuberosum	37.07	8.00e-90	325.00
IUUC-Sar-113222	Sorex araneus	71.90	0.00e+00	803.00
IUUC-Sbi-114272	Sorghum bicolor	37.62	4.00e-93	336.00
IUUC-Sre-115061	Sporisorium reilianum	33.82	9.00e-75	275.00
IUUC-Ssc-116364	Sus scrofa	66.28	0.00e+00	1298.00
IUUC-Tgu-116645	Taeniopygia guttata	68.16	0.00e+00	1328.00
IUUC-Tsy-119212	Tarsius syrichta	68.26	0.00e+00	768.00
IUUC-Tni-119915	Tetraodon nigroviridis	91.67	0.00e+00	1791.00
IUUC-Tca-121765	Theobroma cacao	36.95	2.00e-90	327.00
IUUC-Tre-121887	Trichoderma reesei	29.55	5.00e-61	229.00
IUUC-Tvi-122262	Trichoderma virens	32.59	3.00e-59	223.00
IUUC-Tae-124148	Triticum aestivum	43.08	3.00e-38	154.00
IUUC-Tur-126483	Triticum urartu	37.57	1.00e-91	331.00
IUUC-Tme-127202	Tuber melanosporum	29.19	3.00e-56	213.00
IUUC-Tbe-127350	Tupaia belangeri	66.91	2.00e-154	539.00
IUUC-Ttr-129077	Tursiops truncatus	62.75	0.00e+00	1233.00
IUUC-Uma-129465	Ustilago maydis	34.58	1.00e-77	285.00
IUUC-Vda-129844	Verticillium dahliae	33.83	6.00e-65	242.00
IUUC-Vvi-131397	Vitis vinifera	36.85	3.00e-91	330.00
IUUC-Xtr-132057	Xenopus tropicalis	74.08	0.00e+00	872.00
IUUC-Xma-134139	Xiphophorus maculatus	85.25	0.00e+00	1077.00
IUUC-Yli-134424	Yarrowia lipolytica	32.38	1.00e-64	241.00
IUUC-Zma-135506	Zea mays	35.73	2.00e-91	330.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence