iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Acl-008231

Ensembl Protein ID

CADACLAP00001780

UniProt Accession

A1CNL6; A1CNL6_ASPCL

Genbank Protein ID

EAW07237.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

DS027059

Gene Name

ACLA_019420

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADACLAG00001827	CADACLAT00001827	CADACLAP00001780

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	8.50e-58	195.1	4	242

Active Site

Position(s)	Description	Evidence
93	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
176	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 5    vkewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigN 97
           + +w ++esd g+ft l+e++gvk++ q+eel sLd ++++++  pv+g+++lFk++ +  s + sq +     +   +  +++ffa q+i+N
   Q: 4    GGGWSTIESDEGVFTSLIENLGVKDV-QFEELISLDADTIRSL-SPVYGVIFLFKWIRETPSPTPSQPLD---GTYATNPPENLFFAAQTIQN 91
           579***********************.****************.********************999774...46677788999********* PP
   S: 98   sCatyAllsvllnc....edkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvn 185
           +C+t+A+lsv+ln     ++   + +G++l  +k++t ++ p+ +++al+n+++++ +hn++ar  ++  ++ ++ ++   + +++hf++y++
   Q: 92   ACGTQAILSVILNQdspaTSTHpIAIGPELRAFKDFTTGFPPDLRGEALSNSEAIRTAHNAFARASPFVDETVRGPHD--EDGDVYHFIAYTP 182
           *************977764555689*******************************************9999886665..5899********* PP
   S: 186  ingrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivadrrvi 248
           ++g lyeldgl+p+P+ +g+ ++ + + dkl  v     ri  + ++e rfnl+a+v d rv 
   Q: 183  VGGVLYELDGLRPYPIAHGP-CDADSFPDKLIGVL--QRRIARYPEGETRFNLMAVVRDLRVR 242
           ********************.67788889998888..8*********************9985 PP

Organism

Aspergillus clavatus

Protein Sequence
(Fasta)

MADGGGWSTI ESDEGVFTSL IENLGVKDVQ FEELISLDAD TIRSLSPVYG VIFLFKWIRE 60
TPSPTPSQPL DGTYATNPPE NLFFAAQTIQ NACGTQAILS VILNQDSPAT STHPIAIGPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGACG GCGGCGGCTG GAGCACAATC GAGTCCGATG AGGTATGTCT AGACACAAAC 60
TCACCCACCT GCAATCACAA ACGGACTCCT AAGCAACATA CTACAGGGCG TCTTCACCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0034399--C:nuclear periphery
GO:0031595--C:nuclear proteasome complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

act:ACLA_019420

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	39.21	7.00e-60	222.00
IUUC-Aml-001866	Ailuropoda melanoleuca	36.86	7.00e-55	205.00
IUUC-Atr-002966	Amborella trichopoda	47.89	4.00e-55	206.00
IUUC-Apl-003306	Anas platyrhynchos	33.15	5.00e-47	179.00
IUUC-Aca-004763	Anolis carolinensis	36.71	7.00e-54	202.00
IUUC-Aly-005581	Arabidopsis lyrata	51.90	2.00e-56	211.00
IUUC-Ath-007283	Arabidopsis thaliana	51.05	7.00e-58	215.00
IUUC-Ago-007999	Ashbya gossypii	37.92	4.00e-46	176.00
IUUC-Afl-008557	Aspergillus flavus	80.06	2.00e-140	489.00
IUUC-Afu-008988	Aspergillus fumigatus	86.08	4.00e-152	528.00
IUUC-Ani-009420	Aspergillus nidulans	73.38	3.00e-126	442.00
IUUC-Ang-009859	Aspergillus niger	77.36	7.00e-131	457.00
IUUC-Aor-010145	Aspergillus oryzae	80.06	2.00e-140	489.00
IUUC-Ate-010347	Aspergillus terreus	76.88	4.00e-137	478.00
IUUC-Ame-010791	Astyanax mexicanus	36.47	1.00e-55	208.00
IUUC-Bgr-012298	Blumeria graminis	58.31	2.00e-100	357.00
IUUC-Bta-013251	Bos taurus	36.45	5.00e-55	206.00
IUUC-Bci-013786	Botrytis cinerea	65.15	5.00e-115	405.00
IUUC-Bdi-014132	Brachypodium distachyon	46.95	3.00e-59	219.00
IUUC-Bol-015611	Brassica oleracea	50.19	7.00e-59	218.00
IUUC-Bra-017769	Brassica rapa	46.58	6.00e-59	219.00
IUUC-Cel-018604	Caenorhabditis elegans	36.84	2.00e-51	194.00
IUUC-Cja-019768	Callithrix jacchus	33.33	2.00e-49	187.00
IUUC-Cfa-020207	Canis familiaris	36.86	7.00e-55	205.00
IUUC-Cpo-021925	Cavia porcellus	34.71	2.00e-49	187.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	40.57	9.00e-56	208.00
IUUC-Csa-023958	Chlorocebus sabaeus	36.77	4.00e-55	206.00
IUUC-Cho-024928	Choloepus hoffmanni	41.38	2.00e-11	61.20
IUUC-Cin-025771	Ciona intestinalis	35.80	1.00e-53	201.00
IUUC-Csv-026149	Ciona savignyi	37.78	4.00e-55	206.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	50.84	2.00e-83	300.00
IUUC-Cne-026955	Cryptococcus neoformans	37.50	8.00e-53	198.00
IUUC-Cme-027104	Cyanidioschyzon merolae	35.83	1.00e-41	161.00
IUUC-Dre-027409	Danio rerio	38.46	3.00e-55	206.00
IUUC-Dno-028921	Dasypus novemcinctus	36.33	2.00e-54	204.00
IUUC-Dor-030891	Dipodomys ordii	33.73	4.00e-31	127.00
IUUC-Dse-031170	Dothistroma septosporum	58.49	4.00e-98	349.00
IUUC-Dme-031677	Drosophila melanogaster	40.26	1.00e-56	211.00
IUUC-Ete-032646	Echinops telfairi	41.23	1.00e-34	139.00
IUUC-Eca-033776	Equus caballus	36.30	7.00e-48	182.00
IUUC-Eeu-035305	Erinaceus europaeus	35.35	8.00e-28	115.00
IUUC-Fca-035846	Felis catus	33.43	3.00e-50	190.00
IUUC-Fal-037597	Ficedula albicollis	35.74	2.00e-47	181.00
IUUC-Fox-037670	Fusarium oxysporum	60.67	5.00e-92	328.00
IUUC-Fso-038243	Fusarium solani	60.33	3.00e-91	326.00
IUUC-Gmo-038499	Gadus morhua	35.14	1.00e-47	181.00
IUUC-Ggr-039975	Gaeumannomyces graminis	56.97	2.00e-87	313.00
IUUC-Gga-040904	Gallus gallus	36.18	1.00e-55	208.00
IUUC-Gac-042058	Gasterosteus aculeatus	37.06	6.00e-54	202.00
IUUC-Gma-043030	Glycine max	51.74	8.00e-61	225.00
IUUC-Ggo-044699	Gorilla gorilla	43.60	6.00e-53	199.00
IUUC-Hsa-046227	Homo sapiens	36.66	2.00e-55	207.00
IUUC-Hvu-047359	Hordeum vulgare	39.21	7.00e-60	222.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	33.33	6.00e-50	189.00
IUUC-Lch-049829	Latimeria chalumnae	37.82	7.00e-55	205.00
IUUC-Lpe-050899	Leersia perrieri	40.49	1.00e-60	224.00
IUUC-Loc-052264	Lepisosteus oculatus	38.61	3.00e-53	200.00
IUUC-Lma-053110	Leptosphaeria maculans	62.16	3.00e-92	330.00
IUUC-Laf-053639	Loxodonta africana	36.86	7.00e-55	205.00
IUUC-Mcc-055506	Macaca mulatta	37.30	4.00e-55	206.00
IUUC-Meu-056267	Macropus eugenii	39.68	4.00e-39	154.00
IUUC-Mor-057001	Magnaporthe oryzae	57.41	4.00e-89	319.00
IUUC-Mpo-057608	Magnaporthe poae	59.56	2.00e-54	203.00
IUUC-Mtr-057731	Medicago truncatula	49.81	2.00e-63	233.00
IUUC-Mla-059016	Melampsora laricipopulina	44.66	6.00e-44	168.00
IUUC-Mga-060178	Meleagris gallopavo	35.53	6.00e-49	186.00
IUUC-Mvi-060353	Microbotryum violaceum	37.20	9.00e-53	198.00
IUUC-Mmr-060738	Microcebus murinus	36.86	6.00e-55	205.00
IUUC-Mdo-062625	Monodelphis domestica	41.67	6.00e-44	170.00
IUUC-Mmu-063619	Mus musculus	38.10	1.00e-55	208.00
IUUC-Mac-065301	Musa acuminata	44.23	4.00e-64	236.00
IUUC-Mpu-066058	Mustela putorius furo	36.33	6.00e-55	205.00
IUUC-Mlu-067292	Myotis lucifugus	36.42	8.00e-55	205.00
IUUC-Nfi-068275	Neosartorya fischeri	87.03	2.00e-165	573.00
IUUC-Ncr-068713	Neurospora crassa	59.68	4.00e-110	389.00
IUUC-Nle-069013	Nomascus leucogenys	36.77	4.00e-55	206.00
IUUC-Opr-070628	Ochotona princeps	32.35	2.00e-47	181.00
IUUC-Ont-072688	Oreochromis niloticus	37.26	3.00e-54	203.00
IUUC-Oan-073004	Ornithorhynchus anatinus	42.92	5.00e-46	175.00
IUUC-Ocu-074303	Oryctolagus cuniculus	36.33	9.00e-54	202.00
IUUC-Oba-075002	Oryza barthii	48.26	3.00e-61	226.00
IUUC-Obr-076392	Oryza brachyantha	47.47	2.00e-61	227.00
IUUC-Ogl-077271	Oryza glaberrima	48.26	3.00e-61	226.00
IUUC-Ogu-078493	Oryza glumaepatula	48.65	3.00e-62	230.00
IUUC-Oin-080084	Oryza indica	48.65	3.00e-62	230.00
IUUC-Olo-080803	Oryza longistaminata	48.65	3.00e-62	229.00
IUUC-Ome-081146	Oryza meridionalis	48.65	6.00e-62	229.00
IUUC-Oni-082146	Oryza nivara	48.65	3.00e-62	230.00
IUUC-Opu-083633	Oryza punctata	48.65	4.00e-62	229.00
IUUC-Oru-084789	Oryza rufipogon	48.65	3.00e-62	230.00
IUUC-Osa-086196	Oryza sativa	48.65	3.00e-62	230.00
IUUC-Ola-087126	Oryzias latipes	38.02	1.00e-55	207.00
IUUC-Olu-087665	Ostreococcus lucimarinus	41.20	2.00e-55	207.00
IUUC-Oga-089140	Otolemur garnettii	34.02	1.00e-50	191.00
IUUC-Oar-090296	Ovis aries	36.01	2.00e-53	200.00
IUUC-Ptr-090566	Pan troglodytes	36.66	2.00e-55	207.00
IUUC-Pan-092052	Papio anubis	36.77	4.00e-55	206.00
IUUC-Psi-093723	Pelodiscus sinensis	36.64	1.00e-47	181.00
IUUC-Pma-094568	Petromyzon marinus	44.75	6.00e-48	182.00
IUUC-Pno-095120	Phaeosphaeria nodorum	61.76	1.00e-98	350.00
IUUC-Ppa-095761	Physcomitrella patens	48.47	9.00e-60	221.00
IUUC-Pfo-096210	Poecilia formosa	38.41	4.00e-55	206.00
IUUC-Pab-098463	Pongo abelii	36.66	4.00e-55	206.00
IUUC-Pop-099109	Populus trichocarpa	47.89	4.00e-58	216.00
IUUC-Pca-100108	Procavia capensis	40.91	1.00e-49	188.00
IUUC-Ppe-101176	Prunus persica	47.49	2.00e-56	211.00
IUUC-Pva-102629	Pteropus vampyrus	42.57	2.00e-50	190.00
IUUC-Pgr-103419	Puccinia graminis	42.31	8.00e-45	172.00
IUUC-Pte-104207	Pyrenophora teres	60.23	8.00e-49	184.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	59.74	1.00e-97	347.00
IUUC-Rno-105579	Rattus norvegicus	33.94	1.00e-43	168.00
IUUC-Sha-106894	Sarcophilus harrisii	36.86	5.00e-45	172.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	44.97	7.00e-75	271.00
IUUC-Spo-108371	Schizosaccharomyces pombe	47.60	1.00e-78	284.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	63.16	1.00e-95	340.00
IUUC-Smo-109396	Selaginella moellendorffii	41.16	3.00e-56	210.00
IUUC-Sit-110630	Setaria italica	48.84	5.00e-63	232.00
IUUC-Sly-110972	Solanum lycopersicum	51.45	2.00e-59	220.00
IUUC-Stu-112185	Solanum tuberosum	52.51	5.00e-67	246.00
IUUC-Sar-113294	Sorex araneus	31.75	1.00e-43	168.00
IUUC-Sbi-113951	Sorghum bicolor	49.61	4.00e-64	236.00
IUUC-Ssc-115501	Sus scrofa	35.76	7.00e-50	189.00
IUUC-Tgu-117152	Taeniopygia guttata	35.74	2.00e-47	181.00
IUUC-Tru-118388	Takifugu rubripes	37.06	6.00e-54	202.00
IUUC-Tsy-119109	Tarsius syrichta	36.33	1.00e-54	205.00
IUUC-Tni-120048	Tetraodon nigroviridis	37.38	1.00e-54	204.00
IUUC-Tca-121750	Theobroma cacao	46.49	1.00e-64	238.00
IUUC-Tre-122130	Trichoderma reesei	60.71	3.00e-100	356.00
IUUC-Tvi-122284	Trichoderma virens	58.19	9.00e-94	334.00
IUUC-Tae-124082	Triticum aestivum	39.21	7.00e-60	222.00
IUUC-Tur-126366	Triticum urartu	38.60	7.00e-40	156.00
IUUC-Tme-127187	Tuber melanosporum	56.41	3.00e-102	362.00
IUUC-Tbe-127705	Tupaia belangeri	39.29	4.00e-38	150.00
IUUC-Ttr-128225	Tursiops truncatus	40.48	2.00e-43	169.00
IUUC-Vda-129912	Verticillium dahliae	56.19	2.00e-87	313.00
IUUC-Vpa-130552	Vicugna pacos	41.10	9.00e-44	168.00
IUUC-Vvi-130881	Vitis vinifera	40.17	2.00e-58	217.00
IUUC-Xtr-131934	Xenopus tropicalis	38.34	4.00e-55	206.00
IUUC-Xma-133312	Xiphophorus maculatus	38.41	4.00e-55	206.00
IUUC-Yli-134487	Yarrowia lipolytica	42.31	2.00e-67	247.00
IUUC-Zma-135639	Zea mays	43.39	2.00e-54	204.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence