iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020160

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Genbank Nucleotide ID

AAEX03004472

Gene Name

DCUN1D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000017880.3	ENSCAFT00000028370.3	ENSCAFP00000026384.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	1.20e-84	283.4	87	278

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkd 90
           s ++leelf+rYkd++ed+i++eg+e+fc+dl+vdp++++vL+lawk++aat+c+f+r+ef+dg++a+++dsi+++++++++l +e+k+
   Q: 87   SLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQ 175
           679************************************************************************************** PP
   S: 91   eqkfkdiYrfafnfakd..kgqksldldtaialwkLllaerefklldawlkfLeee..kkksiskDtWnllLefskviakdlsnYdeeg 175
           e+kfkd+Yrf+f+f++d  +gq+sl++++aialwkL+++++++++ld+wl+fL+e+  ++k+is+DtWn++L+f++vi +dlsnY+e++
   Q: 176  EDKFKDLYRFTFQFGLDseEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENpsGIKGISRDTWNMFLNFTQVIGPDLSNYSEDE 264
           ***************998899**********************************9889****************************** PP
   S: 176  aWPvliDefveylk 189
           aWP+l+D+fve+++
   Q: 265  AWPSLFDTFVEWEM 278
           ************85 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MGQCVTKCKN PSSTLGSKNG DRDPSSKSHS RRSAGHREEQ PPACGKPGGD ILVNGTKKAE 60
AATEPCQLPT SSGDAGREPK SNAEESSLQR LEELFRRYKD EREDAILEEG MERFCNDLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCACCTTTAT ATTGGGTTCC TTCCTCCTCT TTCGACTCCT TTCACAGTTT CCTTTCTTGC 60
CTTTCTTTTA CTTAGGGGCA AAAACCAAAG CTTATCTCCA GTTAACTATT TTTCAGTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0005737--C:cytoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0030308--P:negative regulation of cell growth
GO:0043065--P:positive regulation of apoptotic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation
GO:0010332--P:response to gamma radiation
GO:0009314--P:response to radiation
GO:0010225--P:response to UV-C

KEGG

cfa:489983

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001689	Ailuropoda melanoleuca	99.67	2.00e-171	594.00
IUUC-Apl-003497	Anas platyrhynchos	82.57	8.00e-143	499.00
IUUC-Aca-004961	Anolis carolinensis	81.25	4.00e-148	517.00
IUUC-Ani-009241	Aspergillus nidulans	34.98	3.00e-23	102.00
IUUC-Aor-009902	Aspergillus oryzae	33.83	3.00e-11	60.80
IUUC-Ame-011413	Astyanax mexicanus	63.96	3.00e-101	361.00
IUUC-Bta-013338	Bos taurus	97.70	3.00e-167	580.00
IUUC-Cja-019458	Callithrix jacchus	97.37	1.00e-166	578.00
IUUC-Cpo-021835	Cavia porcellus	96.71	8.00e-156	542.00
IUUC-Csa-023328	Chlorocebus sabaeus	97.70	4.00e-167	580.00
IUUC-Cho-024888	Choloepus hoffmanni	96.03	6.00e-165	572.00
IUUC-Cin-025134	Ciona intestinalis	52.24	4.00e-60	225.00
IUUC-Csv-025904	Ciona savignyi	50.41	2.00e-32	130.00
IUUC-Dre-027780	Danio rerio	64.39	3.00e-97	347.00
IUUC-Dno-028866	Dasypus novemcinctus	97.70	7.00e-166	575.00
IUUC-Dor-030387	Dipodomys ordii	96.38	4.00e-164	570.00
IUUC-Dme-032081	Drosophila melanogaster	47.17	3.00e-48	185.00
IUUC-Eca-033857	Equus caballus	97.70	2.00e-168	584.00
IUUC-Eeu-034825	Erinaceus europaeus	90.46	1.00e-151	528.00
IUUC-Fca-036130	Felis catus	99.01	3.00e-170	590.00
IUUC-Fal-037296	Ficedula albicollis	82.57	3.00e-142	497.00
IUUC-Gmo-039626	Gadus morhua	65.12	3.00e-98	351.00
IUUC-Ggr-039959	Gaeumannomyces graminis	26.64	4.00e-15	76.60
IUUC-Gga-040741	Gallus gallus	81.91	1.00e-139	488.00
IUUC-Gac-042271	Gasterosteus aculeatus	66.79	2.00e-93	335.00
IUUC-Ggo-044727	Gorilla gorilla	97.70	4.00e-167	580.00
IUUC-Hsa-046288	Homo sapiens	97.37	8.00e-167	578.00
IUUC-Itr-049054	Ictidomys tridecemlineatus	97.04	4.00e-175	606.00
IUUC-Lch-050289	Latimeria chalumnae	79.02	3.00e-133	468.00
IUUC-Loc-052455	Lepisosteus oculatus	71.94	1.00e-109	389.00
IUUC-Laf-054369	Loxodonta africana	95.72	2.00e-157	548.00
IUUC-Mcc-055413	Macaca mulatta	78.25	6.00e-121	426.00
IUUC-Meu-056535	Macropus eugenii	87.17	1.00e-152	531.00
IUUC-Mga-059290	Meleagris gallopavo	82.57	1.00e-141	495.00
IUUC-Mmr-060689	Microcebus murinus	97.37	1.00e-166	578.00
IUUC-Mdo-062128	Monodelphis domestica	87.50	1.00e-147	515.00
IUUC-Mmu-064396	Mus musculus	95.72	7.00e-173	599.00
IUUC-Mpu-065926	Mustela putorius furo	99.67	2.00e-171	594.00
IUUC-Mlu-067044	Myotis lucifugus	96.05	4.00e-174	603.00
IUUC-Nle-069346	Nomascus leucogenys	97.70	4.00e-167	580.00
IUUC-Opr-070682	Ochotona princeps	97.70	3.00e-155	540.00
IUUC-Ont-071772	Oreochromis niloticus	67.74	5.00e-101	360.00
IUUC-Oan-072765	Ornithorhynchus anatinus	88.69	4.00e-146	510.00
IUUC-Ocu-074272	Oryctolagus cuniculus	92.31	1.00e-118	418.00
IUUC-Ola-087561	Oryzias latipes	68.75	3.00e-106	378.00
IUUC-Oga-088440	Otolemur garnettii	78.04	4.00e-123	433.00
IUUC-Oar-089403	Ovis aries	98.36	1.00e-168	585.00
IUUC-Ptr-091384	Pan troglodytes	97.70	4.00e-167	580.00
IUUC-Pan-092650	Papio anubis	97.70	4.00e-167	580.00
IUUC-Psi-093806	Pelodiscus sinensis	83.88	3.00e-136	477.00
IUUC-Pma-094196	Petromyzon marinus	64.89	8.00e-88	316.00
IUUC-Pfo-096584	Poecilia formosa	70.71	2.00e-104	371.00
IUUC-Pab-098605	Pongo abelii	97.70	4.00e-167	580.00
IUUC-Pca-100933	Procavia capensis	79.28	1.00e-115	409.00
IUUC-Pva-102172	Pteropus vampyrus	92.83	8.00e-161	559.00
IUUC-Rno-105406	Rattus norvegicus	96.71	1.00e-174	605.00
IUUC-Sha-106531	Sarcophilus harrisii	86.84	4.00e-153	533.00
IUUC-Sar-113051	Sorex araneus	76.64	7.00e-116	409.00
IUUC-Ssc-115555	Sus scrofa	98.03	3.00e-168	583.00
IUUC-Tgu-117178	Taeniopygia guttata	83.22	5.00e-144	503.00
IUUC-Tru-117876	Takifugu rubripes	68.18	2.00e-106	379.00
IUUC-Tsy-118790	Tarsius syrichta	95.36	7.00e-134	469.00
IUUC-Tni-119673	Tetraodon nigroviridis	68.64	2.00e-106	378.00
IUUC-Tbe-127429	Tupaia belangeri	97.37	1.00e-166	578.00
IUUC-Ttr-128467	Tursiops truncatus	98.36	2.00e-168	584.00
IUUC-Vpa-130376	Vicugna pacos	68.36	6.00e-97	346.00
IUUC-Xtr-132134	Xenopus tropicalis	79.27	5.00e-122	430.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence