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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063899
UUCD1 version UUC-MuM-00925
Ensembl Protein ID ENSMUSP00000040647.7
UniProt Accession Q80ZK9; WDTC1_MOUSE
Genbank Protein ID AAH48824.1; AAH57107.1
Protein Name WD and tetratricopeptide repeats protein 1
Genbank Nucleotide ID BC048824; BC057107
Gene Name Wdtc1; Gm695
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000037622.14 ENSMUST00000043305.13 ENSMUSP00000040647.7
ENSMUSG00000037622.14 ENSMUST00000105906.1 ENSMUSP00000101526.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
UniProtPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.90e-27 95.3 45 76
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH++ v+cl++   ++ll+sGsdD    vWD+
   Q: 45   GHSGCVNCLEWneKGDLLASGSDDQHTIVWDP 76
           8**********65339***************6 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
 May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Protein Sequence
(Fasta)
MAKVNITRDL IRRQVKERGA LSFERRYHVT DPFIRRLGLE AELQGHSGCV NCLEWNEKGD 60
LLASGSDDQH TIVWDPLHHK KLLSMHTGHT ANIFSVKFLP HAGDRILITG AADSKVHVHD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063899|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGGCCTTGG GCAGGATCTG GGATTAGAAG TTAGCCTGGG CTGCATGGGA AGCTGGAGAC 60
CTATACCGAG ACTCTGTCTC GAAAAGGCAA ATCAAACCAG CGTGGTGGTG CATGCCTGAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063899|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat
Interpro

IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50293--TPR_REGION
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00028--TPR
SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004857--F:enzyme inhibitor activity
GO:0042393--F:histone binding
GO:0042826--F:histone deacetylase binding
GO:0055082--P:cellular chemical homeostasis
GO:0032869--P:cellular response to insulin stimulus
GO:0006006--P:glucose metabolic process
GO:0001701--P:in utero embryonic development
GO:0035264--P:multicellular organism growth
GO:0045717--P:negative regulation of fatty acid biosynthetic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016567--P:protein ubiquitination
GO:0008361--P:regulation of cell size
KEGG mmu:230796
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000083 Aegilops tauschii 33.10 6.00e-31 129.00
IUUC-Aml-001699 Ailuropoda melanoleuca 96.76 0.00e+00 1323.00
IUUC-Atr-002509 Amborella trichopoda 31.65 4.00e-50 192.00
IUUC-Apl-003379 Anas platyrhynchos 91.59 0.00e+00 1262.00
IUUC-Aca-005202 Anolis carolinensis 89.10 0.00e+00 1233.00
IUUC-Aly-006475 Arabidopsis lyrata 32.08 1.00e-52 201.00
IUUC-Ath-007666 Arabidopsis thaliana 31.42 2.00e-52 200.00
IUUC-Afl-008592 Aspergillus flavus 28.25 9.00e-26 112.00
IUUC-Ani-009263 Aspergillus nidulans 27.90 1.00e-25 112.00
IUUC-Ang-009671 Aspergillus niger 27.61 3.00e-26 115.00
IUUC-Aor-010229 Aspergillus oryzae 27.97 6.00e-26 113.00
IUUC-Ame-010988 Astyanax mexicanus 80.87 0.00e+00 989.00
IUUC-Bdi-014100 Brachypodium distachyon 30.80 1.00e-50 194.00
IUUC-Bol-016409 Brassica oleracea 31.98 2.00e-51 197.00
IUUC-Bra-016979 Brassica rapa 32.62 6.00e-52 199.00
IUUC-Cel-018561 Caenorhabditis elegans 32.25 1.00e-33 137.00
IUUC-Cja-019212 Callithrix jacchus 94.84 0.00e+00 1279.00
IUUC-Cfa-020200 Canis familiaris 96.61 0.00e+00 1322.00
IUUC-Cpo-021739 Cavia porcellus 97.20 0.00e+00 1326.00
IUUC-Cre-022659 Chlamydomonas reinhardtii 33.46 6.00e-34 139.00
IUUC-Csa-023648 Chlorocebus sabaeus 96.76 0.00e+00 1321.00
IUUC-Cin-025155 Ciona intestinalis 44.22 4.00e-64 238.00
IUUC-Csv-026289 Ciona savignyi 46.34 4.00e-150 524.00
IUUC-Cme-027316 Cyanidioschyzon merolae 27.99 3.00e-27 117.00
IUUC-Dre-028745 Danio rerio 79.50 0.00e+00 1099.00
IUUC-Dno-029403 Dasypus novemcinctus 90.86 0.00e+00 1231.00
IUUC-Dor-030332 Dipodomys ordii 86.89 0.00e+00 1195.00
IUUC-Dme-031811 Drosophila melanogaster 37.28 5.00e-108 385.00
IUUC-Ete-032331 Echinops telfairi 90.26 5.00e-143 501.00
IUUC-Eca-033783 Equus caballus 96.32 0.00e+00 1324.00
IUUC-Eeu-034732 Erinaceus europaeus 94.69 0.00e+00 1281.00
IUUC-Fca-036543 Felis catus 96.76 0.00e+00 1323.00
IUUC-Fal-037245 Ficedula albicollis 91.08 0.00e+00 1273.00
IUUC-Gmo-039346 Gadus morhua 77.70 0.00e+00 1108.00
IUUC-Gga-041034 Gallus gallus 91.45 0.00e+00 1257.00
IUUC-Gac-041297 Gasterosteus aculeatus 78.50 0.00e+00 1094.00
IUUC-Gma-042727 Glycine max 31.41 3.00e-47 183.00
IUUC-Ggo-045309 Gorilla gorilla 96.76 0.00e+00 1321.00
IUUC-Hsa-046622 Homo sapiens 96.76 0.00e+00 1321.00
IUUC-Itr-049052 Ictidomys tridecemlineatus 95.97 0.00e+00 1150.00
IUUC-Lch-049810 Latimeria chalumnae 84.60 0.00e+00 1142.00
IUUC-Lpe-051600 Leersia perrieri 28.97 1.00e-67 251.00
IUUC-Loc-052088 Lepisosteus oculatus 84.37 0.00e+00 1169.00
IUUC-Laf-054097 Loxodonta africana 96.31 0.00e+00 1321.00
IUUC-Mcc-054848 Macaca mulatta 96.76 0.00e+00 1321.00
IUUC-Meu-056022 Macropus eugenii 71.78 0.00e+00 790.00
IUUC-Mtr-057735 Medicago truncatula 29.80 1.00e-45 178.00
IUUC-Mga-059622 Meleagris gallopavo 91.45 0.00e+00 1259.00
IUUC-Mmr-060709 Microcebus murinus 96.46 0.00e+00 1323.00
IUUC-Mdo-062401 Monodelphis domestica 93.95 0.00e+00 1281.00
IUUC-Mac-064840 Musa acuminata 30.26 2.00e-47 184.00
IUUC-Mpu-066268 Mustela putorius furo 96.61 0.00e+00 1321.00
IUUC-Mlu-067211 Myotis lucifugus 96.34 0.00e+00 840.00
IUUC-Nle-070019 Nomascus leucogenys 96.61 0.00e+00 1298.00
IUUC-Opr-071008 Ochotona princeps 96.31 0.00e+00 1324.00
IUUC-Ont-072123 Oreochromis niloticus 80.27 0.00e+00 1125.00
IUUC-Ocu-074166 Oryctolagus cuniculus 95.87 0.00e+00 1320.00
IUUC-Oba-075298 Oryza barthii 29.60 1.00e-42 168.00
IUUC-Obr-076849 Oryza brachyantha 28.54 2.00e-41 164.00
IUUC-Ogl-077515 Oryza glaberrima 29.60 1.00e-42 168.00
IUUC-Ogu-077968 Oryza glumaepatula 29.62 5.00e-39 155.00
IUUC-Oin-079231 Oryza indica 29.75 5.00e-38 152.00
IUUC-Olo-081045 Oryza longistaminata 29.75 6.00e-37 150.00
IUUC-Ome-081395 Oryza meridionalis 29.54 1.00e-36 148.00
IUUC-Oni-082801 Oryza nivara 29.60 9.00e-43 168.00
IUUC-Opu-083585 Oryza punctata 29.82 2.00e-42 167.00
IUUC-Oru-085163 Oryza rufipogon 28.85 6.00e-42 166.00
IUUC-Osa-085550 Oryza sativa 34.00 1.00e-28 120.00
IUUC-Ola-086925 Oryzias latipes 77.91 0.00e+00 1090.00
IUUC-Oga-088095 Otolemur garnettii 95.29 0.00e+00 1316.00
IUUC-Oar-090285 Ovis aries 95.13 0.00e+00 1287.00
IUUC-Ptr-091221 Pan troglodytes 96.76 0.00e+00 1321.00
IUUC-Pan-091771 Papio anubis 96.76 0.00e+00 1321.00
IUUC-Psi-093977 Pelodiscus sinensis 90.71 0.00e+00 1253.00
IUUC-Ppa-095373 Physcomitrella patens 30.95 9.00e-50 192.00
IUUC-Pfo-096640 Poecilia formosa 79.65 0.00e+00 1107.00
IUUC-Pab-098513 Pongo abelii 96.76 0.00e+00 1321.00
IUUC-Pop-098837 Populus trichocarpa 31.52 9.00e-45 175.00
IUUC-Pca-101095 Procavia capensis 87.46 0.00e+00 1168.00
IUUC-Ppe-101507 Prunus persica 30.15 3.00e-46 180.00
IUUC-Pva-102444 Pteropus vampyrus 97.05 0.00e+00 1326.00
IUUC-Rno-105952 Rattus norvegicus 98.82 0.00e+00 1350.00
IUUC-Sha-106614 Sarcophilus harrisii 94.40 0.00e+00 1295.00
IUUC-Smo-108844 Selaginella moellendorffii 32.50 7.00e-47 182.00
IUUC-Sit-110154 Setaria italica 33.44 2.00e-40 160.00
IUUC-Sly-111707 Solanum lycopersicum 31.43 3.00e-48 186.00
IUUC-Sar-113129 Sorex araneus 79.53 0.00e+00 1049.00
IUUC-Sbi-113858 Sorghum bicolor 27.91 2.00e-52 200.00
IUUC-Ssc-116275 Sus scrofa 97.35 0.00e+00 1328.00
IUUC-Tgu-117507 Taeniopygia guttata 91.45 0.00e+00 1262.00
IUUC-Tru-117969 Takifugu rubripes 77.47 0.00e+00 1108.00
IUUC-Tsy-119374 Tarsius syrichta 84.55 0.00e+00 839.00
IUUC-Tni-119887 Tetraodon nigroviridis 75.80 0.00e+00 1050.00
IUUC-Tca-121722 Theobroma cacao 32.53 3.00e-48 187.00
IUUC-Tae-124854 Triticum aestivum 34.84 2.00e-36 147.00
IUUC-Tur-125968 Triticum urartu 35.34 3.00e-32 135.00
IUUC-Tme-126910 Tuber melanosporum 34.26 3.00e-24 107.00
IUUC-Tbe-127511 Tupaia belangeri 90.53 2.00e-86 313.00
IUUC-Ttr-128390 Tursiops truncatus 93.67 0.00e+00 1249.00
IUUC-Uma-129509 Ustilago maydis 26.85 4.00e-13 70.10
IUUC-Vpa-130124 Vicugna pacos 57.84 4.00e-143 501.00
IUUC-Xtr-132290 Xenopus tropicalis 76.25 0.00e+00 1039.00
IUUC-Xma-134025 Xiphophorus maculatus 79.20 0.00e+00 1102.00
Created Date 25-Jun-2017

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