iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045627

Ensembl Protein ID

ENSGGOP00000003243.2

UniProt Accession

G3QL96; G3QL96_GORGO

Protein Name

Uncharacterized protein

Gene Name

ERCC8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000003300.2	ENSGGOT00000003317.2	ENSGGOP00000003243.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-24	84.6	98	130

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlr 31
           H  sv  +++  +d +++ s+s D+t+kvWD+ 
   Q: 98   HRYSVETVQWypHDtGMFTSSSFDKTLKVWDTN 130
           888999*****9778****************75 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MLGFLSARQT GLEDPLRLRR AESTRRVLGL ELNKDRDVER IHGGGINTLD IEPVEGRYML 60
SGGSDGVIVL YDLENSSRQS YYTCKAVCSI GRDHPDVHRY SVETVQWYPH DTGMFTSSSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCATGGCGA CGTCCAGTTC TCCAGCCGGT GTGAGGACAC GATATGCTGG GGTTTTTGTC 60
CGCACGCCAA ACGGGTTTGG AGGACCCTCT TCGCCTTCGG AGAGCAGAGT CAACACGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0016363--C:nuclear matrix
GO:0000109--C:nucleotide-excision repair complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006979--P:response to oxidative stress
GO:0009411--P:response to UV
GO:0010165--P:response to X-ray
GO:0006283--P:transcription-coupled nucleotide-excision repair

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001170	Aegilops tauschii	30.25	6.00e-35	142.00
IUUC-Aml-002201	Ailuropoda melanoleuca	86.14	0.00e+00	711.00
IUUC-Atr-002784	Amborella trichopoda	35.55	2.00e-33	136.00
IUUC-Apl-003202	Anas platyrhynchos	75.00	3.00e-172	597.00
IUUC-Aca-004708	Anolis carolinensis	74.15	1.00e-159	555.00
IUUC-Aly-006144	Arabidopsis lyrata	32.27	2.00e-51	196.00
IUUC-Ath-006673	Arabidopsis thaliana	31.22	2.00e-46	179.00
IUUC-Acl-008195	Aspergillus clavatus	34.69	1.00e-35	144.00
IUUC-Afl-008406	Aspergillus flavus	35.14	7.00e-34	137.00
IUUC-Afu-008759	Aspergillus fumigatus	32.47	2.00e-33	136.00
IUUC-Ani-009380	Aspergillus nidulans	33.88	4.00e-34	139.00
IUUC-Ang-009820	Aspergillus niger	35.69	3.00e-33	135.00
IUUC-Aor-010092	Aspergillus oryzae	35.51	1.00e-38	154.00
IUUC-Ate-010491	Aspergillus terreus	34.51	2.00e-38	153.00
IUUC-Bta-012825	Bos taurus	86.39	0.00e+00	713.00
IUUC-Bci-013856	Botrytis cinerea	30.03	8.00e-46	177.00
IUUC-Bdi-014899	Brachypodium distachyon	32.35	4.00e-58	219.00
IUUC-Bol-015337	Brassica oleracea	37.32	2.00e-38	153.00
IUUC-Bra-018089	Brassica rapa	37.32	1.00e-38	153.00
IUUC-Cja-018725	Callithrix jacchus	88.61	0.00e+00	725.00
IUUC-Cfa-021162	Canis familiaris	86.14	0.00e+00	710.00
IUUC-Cpo-022190	Cavia porcellus	86.39	0.00e+00	715.00
IUUC-Cre-022960	Chlamydomonas reinhardtii	37.29	2.00e-33	136.00
IUUC-Csa-023610	Chlorocebus sabaeus	91.58	0.00e+00	747.00
IUUC-Cho-024689	Choloepus hoffmanni	83.86	0.00e+00	641.00
IUUC-Cin-025324	Ciona intestinalis	35.92	5.00e-67	248.00
IUUC-Csv-026059	Ciona savignyi	35.21	2.00e-60	226.00
IUUC-Cgl-026384	Colletotrichum gloeosporioides	30.19	1.00e-29	124.00
IUUC-Dre-028696	Danio rerio	67.08	3.00e-161	560.00
IUUC-Dno-029102	Dasypus novemcinctus	86.39	0.00e+00	714.00
IUUC-Dor-030361	Dipodomys ordii	73.38	6.00e-169	586.00
IUUC-Dse-031167	Dothistroma septosporum	27.62	6.00e-38	151.00
IUUC-Ete-032856	Echinops telfairi	74.38	6.00e-175	606.00
IUUC-Eca-033611	Equus caballus	85.84	3.00e-174	604.00
IUUC-Eeu-034583	Erinaceus europaeus	64.11	4.00e-139	487.00
IUUC-Fca-036481	Felis catus	86.32	0.00e+00	712.00
IUUC-Fal-037327	Ficedula albicollis	71.51	7.00e-148	516.00
IUUC-Fox-037684	Fusarium oxysporum	28.73	3.00e-36	146.00
IUUC-Fso-038306	Fusarium solani	30.05	2.00e-44	172.00
IUUC-Gmo-039043	Gadus morhua	63.00	5.00e-149	520.00
IUUC-Ggr-039783	Gaeumannomyces graminis	26.85	2.00e-30	127.00
IUUC-Gga-041085	Gallus gallus	78.12	1.00e-164	572.00
IUUC-Gac-042328	Gasterosteus aculeatus	61.98	2.00e-142	498.00
IUUC-Gma-043004	Glycine max	29.70	2.00e-38	153.00
IUUC-Hsa-046028	Homo sapiens	91.58	0.00e+00	747.00
IUUC-Hvu-047678	Hordeum vulgare	31.33	2.00e-31	129.00
IUUC-Itr-048648	Ictidomys tridecemlineatus	87.38	0.00e+00	723.00
IUUC-Kpa-049386	Komagataella pastoris	28.92	2.00e-34	140.00
IUUC-Lch-050590	Latimeria chalumnae	72.44	2.00e-145	508.00
IUUC-Lpe-051725	Leersia perrieri	32.68	4.00e-35	142.00
IUUC-Loc-051788	Lepisosteus oculatus	69.95	4.00e-166	577.00
IUUC-Lma-053082	Leptosphaeria maculans	31.39	5.00e-46	178.00
IUUC-Laf-053809	Loxodonta africana	86.88	0.00e+00	724.00
IUUC-Mcc-054998	Macaca mulatta	87.85	3.00e-145	507.00
IUUC-Meu-055929	Macropus eugenii	71.64	3.00e-167	580.00
IUUC-Mor-057003	Magnaporthe oryzae	31.95	6.00e-40	158.00
IUUC-Mtr-057921	Medicago truncatula	30.89	1.00e-50	193.00
IUUC-Mga-059449	Meleagris gallopavo	63.61	6.00e-120	423.00
IUUC-Mmr-061609	Microcebus murinus	87.41	0.00e+00	697.00
IUUC-Mdo-062564	Monodelphis domestica	79.85	0.00e+00	668.00
IUUC-Mmu-063904	Mus musculus	82.34	0.00e+00	687.00
IUUC-Mac-064716	Musa acuminata	27.85	8.00e-42	164.00
IUUC-Mpu-066617	Mustela putorius furo	85.89	0.00e+00	709.00
IUUC-Mlu-067054	Myotis lucifugus	83.91	0.00e+00	693.00
IUUC-Nfi-068467	Neosartorya fischeri	32.28	3.00e-27	115.00
IUUC-Nle-069731	Nomascus leucogenys	91.58	0.00e+00	747.00
IUUC-Opr-070297	Ochotona princeps	71.58	2.00e-70	259.00
IUUC-Ont-072558	Oreochromis niloticus	65.43	9.00e-150	522.00
IUUC-Oan-072864	Ornithorhynchus anatinus	84.21	2.00e-26	109.00
IUUC-Ocu-074415	Oryctolagus cuniculus	86.88	0.00e+00	719.00
IUUC-Oba-075759	Oryza barthii	32.69	5.00e-53	201.00
IUUC-Obr-076387	Oryza brachyantha	36.76	3.00e-37	149.00
IUUC-Ogl-077924	Oryza glaberrima	40.48	2.00e-17	82.00
IUUC-Ogu-079041	Oryza glumaepatula	34.99	3.00e-52	198.00
IUUC-Oin-079389	Oryza indica	32.68	7.00e-44	171.00
IUUC-Olo-080916	Oryza longistaminata	49.12	6.00e-13	67.00
IUUC-Ome-081471	Oryza meridionalis	31.69	8.00e-35	141.00
IUUC-Oni-082449	Oryza nivara	33.16	7.00e-50	191.00
IUUC-Opu-083210	Oryza punctata	32.67	8.00e-53	201.00
IUUC-Oru-085159	Oryza rufipogon	32.69	4.00e-53	202.00
IUUC-Osa-085926	Oryza sativa	39.19	2.00e-32	131.00
IUUC-Ola-087084	Oryzias latipes	64.09	4.00e-153	534.00
IUUC-Olu-087853	Ostreococcus lucimarinus	25.79	2.00e-31	129.00
IUUC-Oga-089008	Otolemur garnettii	86.35	0.00e+00	713.00
IUUC-Oar-089259	Ovis aries	86.39	0.00e+00	711.00
IUUC-Ptr-091112	Pan troglodytes	90.77	0.00e+00	737.00
IUUC-Pan-092303	Papio anubis	99.22	3.00e-73	266.00
IUUC-Psi-093050	Pelodiscus sinensis	75.68	0.00e+00	635.00
IUUC-Pma-094259	Petromyzon marinus	52.32	7.00e-117	413.00
IUUC-Pno-094798	Phaeosphaeria nodorum	29.57	4.00e-43	169.00
IUUC-Ppa-095477	Physcomitrella patens	30.20	3.00e-52	199.00
IUUC-Pfo-096855	Poecilia formosa	62.32	1.00e-148	519.00
IUUC-Pab-098096	Pongo abelii	90.84	0.00e+00	741.00
IUUC-Pop-098800	Populus trichocarpa	30.88	1.00e-61	230.00
IUUC-Pca-100187	Procavia capensis	91.75	9.00e-113	400.00
IUUC-Ppe-101759	Prunus persica	30.51	3.00e-60	226.00
IUUC-Pva-102438	Pteropus vampyrus	77.56	7.00e-91	327.00
IUUC-Pte-104197	Pyrenophora teres	30.99	4.00e-43	169.00
IUUC-Pyt-104421	Pyrenophora triticirepentis	31.55	3.00e-43	169.00
IUUC-Rno-106087	Rattus norvegicus	82.84	0.00e+00	693.00
IUUC-Sce-106276	Saccharomyces cerevisiae	44.19	2.00e-07	50.80
IUUC-Sha-106831	Sarcophilus harrisii	76.62	0.00e+00	635.00
IUUC-Sja-107681	Schizosaccharomyces japonicus	31.59	2.00e-48	186.00
IUUC-Spo-108294	Schizosaccharomyces pombe	35.26	4.00e-57	215.00
IUUC-Ssl-108613	Sclerotinia sclerotiorum	31.92	6.00e-47	181.00
IUUC-Smo-109008	Selaginella moellendorffii	38.15	2.00e-65	242.00
IUUC-Sit-110300	Setaria italica	31.40	3.00e-50	192.00
IUUC-Sly-111441	Solanum lycopersicum	34.16	5.00e-29	122.00
IUUC-Stu-111995	Solanum tuberosum	34.16	5.00e-29	122.00
IUUC-Sar-113196	Sorex araneus	72.32	5.00e-107	380.00
IUUC-Sbi-113790	Sorghum bicolor	39.63	5.00e-35	142.00
IUUC-Ssc-115609	Sus scrofa	86.63	0.00e+00	717.00
IUUC-Tgu-116927	Taeniopygia guttata	74.69	6.00e-176	609.00
IUUC-Tru-118164	Takifugu rubripes	65.11	5.00e-158	550.00
IUUC-Tsy-119151	Tarsius syrichta	82.09	0.00e+00	664.00
IUUC-Tni-120896	Tetraodon nigroviridis	64.36	1.00e-148	519.00
IUUC-Tca-121592	Theobroma cacao	35.15	6.00e-36	145.00
IUUC-Tre-122023	Trichoderma reesei	31.55	1.00e-39	157.00
IUUC-Tvi-122507	Trichoderma virens	32.45	7.00e-41	161.00
IUUC-Tae-125614	Triticum aestivum	36.42	1.00e-34	139.00
IUUC-Tur-126092	Triticum urartu	37.82	3.00e-22	99.80
IUUC-Tbe-127422	Tupaia belangeri	78.34	2.00e-70	259.00
IUUC-Ttr-129097	Tursiops truncatus	83.91	0.00e+00	692.00
IUUC-Vda-130014	Verticillium dahliae	32.39	5.00e-43	168.00
IUUC-Vpa-130782	Vicugna pacos	87.13	0.00e+00	723.00
IUUC-Vvi-131494	Vitis vinifera	32.68	2.00e-35	142.00
IUUC-Xtr-132165	Xenopus tropicalis	71.66	7.00e-164	569.00
IUUC-Xma-133205	Xiphophorus maculatus	62.96	5.00e-152	530.00
IUUC-Yli-134614	Yarrowia lipolytica	33.17	8.00e-53	201.00
IUUC-Zma-135861	Zea mays	30.98	3.00e-45	176.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence