iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Dme-031951

UUCD1 version

UUC-DrM-00557

Ensembl Protein ID

FBpp0082303

UniProt Accession

Q9VFR8; Q9VFR8_DROME

Genbank Protein ID

AAF54982.1; CBA35274.1; CBA35275.1; CBA35276.1; CBA35277.1; CBA35278.1; CBA35279.1; CBA35280.1; CBA35281.1; CBA35282.1; CBA35283.1; CBA35284.1; CBA35285.1

Protein Name

CG9602 protein; Ubiquitin conjugating enzyme 87F

Genbank Nucleotide ID

AE014297; FN544193; FN544194; FN544195; FN544196; FN544197; FN544198; FN544199; FN544200; FN544201; FN544202; FN544203; FN544204

Gene Name

Ubc87F; CG9602; Dmel_CG9602

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0267383	FBtr0082838	FBpp0082303

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
IID	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.30e-49	167.5	10	157

Active Site

Position(s)	Description	Evidence
90	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........e 88
           l+++l+el+++p+eg+sa++v++sd+++wev+i+Gp+dt Yegg+Fk+++ fp++YP++PPk+kf+t+i+hPn++++G+vC+sil+            
   Q: 10   LNRQLSELQRHPVEGFSAGLVSDSDIFKWEVVIIGPPDTLYEGGFFKAHLIFPKEYPLRPPKMKFITEIWHPNIDKAGDVCISILHepgddkwgyekA 107
           57899********************************************************************************8888899999999 PP
   S: 89   eekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ee+W p+++ve++lls++s+l++pn es++n++aa+++++n +e+k+kv 
   Q: 108  EERWLPVHTVETILLSVISMLTDPNDESAANVDAAKEYRENYAEFKRKVT 157
           ***********************************************995 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSELQASLLL NRQLSELQRH PVEGFSAGLV SDSDIFKWEV VIIGPPDTLY EGGFFKAHLI 60
FPKEYPLRPP KMKFITEIWH PNIDKAGDVC ISILHEPGDD KWGYEKAEER WLPVHTVETI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCGTAGTT CAGCCTCCGT AGAAGTAAAC CAGAAAGTGA CTCGAAACAA TTGAACAAAA 60
TTCCAGTAAG TACAAATGTG ATTGTACTTA AATGGCTTAT CCCACTGATG GTGCTTATCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

dme:Dmel_CG9602

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ani-009165	Aspergillus nidulans	56.55	1.00e-47	181.00
IUUC-Cel-018162	Caenorhabditis elegans	79.63	4.00e-77	279.00
IUUC-Cin-025131	Ciona intestinalis	68.86	2.00e-70	256.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence