iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-24	85.5	501	532
UBD/Beta-Prp	3.20e-70	237.1	293	573

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH++++++l+f +   +l+s+s+D+t+++WD+
   Q: 501  GHEGPISGLCFnPMkSILASASWDKTVRLWDM 532
           8**********988889**************6 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseD.rtikvwdlstgkcvhtlkghedsvlsl 100
           +t+ ++++++ ll+tg+++g   ++++ + +l++sls  ++ v++v ++++g++++ g +  + + vw+ ++ ++v + +gh +s ++l
   Q: 293  LTAAAYHKKTHLLVTGFASGIFHLHELPEFNLIHSLSISDQRVASVAINSSGDWIAFGCSGlGQLLVWEWQSESYVLKQQGHFNSMVAL 381
           788999*******************************************************9*************************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfd 189
           ++sp+g+++v+G++d  ++vw++ +g c+  tl++h++ v++v++  +g ++v++slD+tvr +dl + +  rt+t+    +  ++++d
   Q: 382  AYSPDGQYIVTGGDDGKVKVWNTLSGFCFV-TLTEHSSGVTGVTFTATGHVIVTSSLDGTVRAYDLHRYRNFRTFTSPRPTQFSCVAVD 469
           ******************************.********************************************************** PP
   S: 190  sngkelvsgsldg.tvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl.rsgdllktlqlhnssvisvavlsfg 276
           s+g+ + +g++d+  + +w++qtg+ ++ l gh+ +++ + f p + +l+s+s D+++r+Wd+ +s  +  tl+l  s v +v++ +++
   Q: 470  SSGEIVSAGAQDSfEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSILASASWDKTVRLWDMfDSWRTKETLSL-TSDVLAVTY-RPD 556
           ************95699********************************************86356666777777.457777777.9** PP
   S: 277  dnvlvlgsedskvniwk 293
           + +l+ ++ +s++ +w+
   Q: 557  GAELAVATLNSQITFWD 573
           ****************8 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MKFAYRFSNL LGTVYRCGNL NFSRDGNSVI SPVGNRVTVF DLKNNRSDTL PLATKYNIKC 60
VGLSPDGRLA IIVDEGGAAL LVSLVCRSVL HHFHFKGSVH SVSFSPDGRK FVITKGNIAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGAACACTA TGGTTGAGGC CCCGCCCCCG GAATTACGCA TTTTGAGCGC CGGAGATAGT 60
TCGTATTCCG GAAGTGGCTG GAGCAGGGTT CCGCACGTGT GGCTCCGGGA TGAAATTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027145--PWP2
IPR011047--Quinoprotein_ADH-like_supfam
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04003--Utp12
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000028--P:ribosomal small subunit assembly

KEGG

rno:690297

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001932	Ailuropoda melanoleuca	86.00	0.00e+00	1631.00
IUUC-Atr-003033	Amborella trichopoda	46.73	2.00e-166	580.00
IUUC-Apl-003219	Anas platyrhynchos	75.87	0.00e+00	1428.00
IUUC-Aca-004950	Anolis carolinensis	74.67	0.00e+00	1422.00
IUUC-Aly-006213	Arabidopsis lyrata	39.73	0.00e+00	653.00
IUUC-Ath-006593	Arabidopsis thaliana	39.45	0.00e+00	654.00
IUUC-Ago-007916	Ashbya gossypii	43.76	0.00e+00	726.00
IUUC-Acl-008225	Aspergillus clavatus	44.63	0.00e+00	784.00
IUUC-Afl-008390	Aspergillus flavus	44.62	0.00e+00	781.00
IUUC-Afu-009039	Aspergillus fumigatus	44.73	0.00e+00	781.00
IUUC-Ani-009228	Aspergillus nidulans	42.17	0.00e+00	689.00
IUUC-Ang-009663	Aspergillus niger	43.92	0.00e+00	759.00
IUUC-Aor-009923	Aspergillus oryzae	44.62	0.00e+00	781.00
IUUC-Ate-010264	Aspergillus terreus	45.34	0.00e+00	791.00
IUUC-Ame-010790	Astyanax mexicanus	66.67	1.00e-163	569.00
IUUC-Bgr-012066	Blumeria graminis	43.72	0.00e+00	770.00
IUUC-Bta-012399	Bos taurus	89.50	0.00e+00	1616.00
IUUC-Bci-013757	Botrytis cinerea	50.82	2.00e-173	603.00
IUUC-Bdi-015028	Brachypodium distachyon	40.89	0.00e+00	669.00
IUUC-Bol-016521	Brassica oleracea	41.05	0.00e+00	665.00
IUUC-Bra-017096	Brassica rapa	40.83	0.00e+00	665.00
IUUC-Cel-018690	Caenorhabditis elegans	39.23	0.00e+00	644.00
IUUC-Cja-019229	Callithrix jacchus	87.90	0.00e+00	1630.00
IUUC-Cfa-020504	Canis familiaris	86.67	0.00e+00	1640.00
IUUC-Cpo-021574	Cavia porcellus	90.55	0.00e+00	1689.00
IUUC-Cre-022756	Chlamydomonas reinhardtii	42.75	4.00e-152	532.00
IUUC-Csa-023436	Chlorocebus sabaeus	89.87	0.00e+00	1654.00
IUUC-Cin-025397	Ciona intestinalis	57.30	0.00e+00	877.00
IUUC-Csv-026194	Ciona savignyi	58.38	0.00e+00	646.00
IUUC-Cgl-026684	Colletotrichum gloeosporioides	41.84	0.00e+00	688.00
IUUC-Cne-027031	Cryptococcus neoformans	44.87	0.00e+00	808.00
IUUC-Cme-027276	Cyanidioschyzon merolae	31.56	3.00e-110	393.00
IUUC-Dre-027514	Danio rerio	65.94	0.00e+00	1269.00
IUUC-Dno-029191	Dasypus novemcinctus	87.03	0.00e+00	1408.00
IUUC-Dor-030149	Dipodomys ordii	91.09	0.00e+00	1695.00
IUUC-Dse-031260	Dothistroma septosporum	50.88	1.00e-166	580.00
IUUC-Dme-032043	Drosophila melanogaster	46.27	0.00e+00	835.00
IUUC-Ete-033102	Echinops telfairi	84.97	0.00e+00	1023.00
IUUC-Eca-033223	Equus caballus	89.43	0.00e+00	1673.00
IUUC-Fca-035795	Felis catus	80.54	0.00e+00	1473.00
IUUC-Fal-036830	Ficedula albicollis	75.37	0.00e+00	1427.00
IUUC-Fox-037835	Fusarium oxysporum	42.00	0.00e+00	699.00
IUUC-Fso-038324	Fusarium solani	49.75	6.00e-170	591.00
IUUC-Gmo-039355	Gadus morhua	70.15	0.00e+00	1315.00
IUUC-Ggr-039840	Gaeumannomyces graminis	48.82	7.00e-164	571.00
IUUC-Gga-040907	Gallus gallus	78.54	0.00e+00	915.00
IUUC-Gac-042624	Gasterosteus aculeatus	71.25	0.00e+00	1305.00
IUUC-Gma-043034	Glycine max	40.38	0.00e+00	689.00
IUUC-Hsa-046145	Homo sapiens	89.65	0.00e+00	1676.00
IUUC-Hvu-047416	Hordeum vulgare	40.45	0.00e+00	660.00
IUUC-Itr-049083	Ictidomys tridecemlineatus	90.20	0.00e+00	1698.00
IUUC-Kpa-049150	Komagataella pastoris	44.11	0.00e+00	733.00
IUUC-Lch-049460	Latimeria chalumnae	71.76	0.00e+00	1236.00
IUUC-Lpe-050840	Leersia perrieri	47.21	8.00e-167	581.00
IUUC-Loc-052733	Lepisosteus oculatus	70.87	0.00e+00	1350.00
IUUC-Lma-053277	Leptosphaeria maculans	49.84	4.00e-173	602.00
IUUC-Laf-054294	Loxodonta africana	87.96	0.00e+00	1575.00
IUUC-Mcc-054624	Macaca mulatta	90.63	0.00e+00	1670.00
IUUC-Meu-056665	Macropus eugenii	71.18	0.00e+00	1001.00
IUUC-Mor-057288	Magnaporthe oryzae	48.76	1.00e-168	587.00
IUUC-Mpo-057594	Magnaporthe poae	43.92	0.00e+00	710.00
IUUC-Mtr-058700	Medicago truncatula	40.07	0.00e+00	700.00
IUUC-Mla-058846	Melampsora laricipopulina	44.29	0.00e+00	759.00
IUUC-Mga-059207	Meleagris gallopavo	68.83	0.00e+00	1254.00
IUUC-Mvi-060327	Microbotryum violaceum	46.05	0.00e+00	796.00
IUUC-Mmr-061264	Microcebus murinus	90.18	0.00e+00	1614.00
IUUC-Mdo-062327	Monodelphis domestica	81.63	0.00e+00	1558.00
IUUC-Mmu-063542	Mus musculus	96.70	0.00e+00	1739.00
IUUC-Mac-065142	Musa acuminata	41.27	0.00e+00	684.00
IUUC-Mpu-066098	Mustela putorius furo	85.83	0.00e+00	1404.00
IUUC-Mlu-067056	Myotis lucifugus	83.97	0.00e+00	1491.00
IUUC-Nfi-068323	Neosartorya fischeri	44.55	0.00e+00	785.00
IUUC-Ncr-068925	Neurospora crassa	43.29	0.00e+00	772.00
IUUC-Nle-068970	Nomascus leucogenys	90.00	0.00e+00	1664.00
IUUC-Opr-070966	Ochotona princeps	93.87	0.00e+00	645.00
IUUC-Ont-071252	Oreochromis niloticus	72.02	0.00e+00	1332.00
IUUC-Oan-072737	Ornithorhynchus anatinus	77.86	0.00e+00	1455.00
IUUC-Oba-075794	Oryza barthii	39.89	0.00e+00	638.00
IUUC-Obr-076617	Oryza brachyantha	40.65	0.00e+00	670.00
IUUC-Ogl-077022	Oryza glaberrima	40.99	0.00e+00	672.00
IUUC-Ogu-078757	Oryza glumaepatula	32.58	5.00e-127	448.00
IUUC-Oin-079813	Oryza indica	40.77	0.00e+00	667.00
IUUC-Olo-080265	Oryza longistaminata	40.99	0.00e+00	673.00
IUUC-Ome-081494	Oryza meridionalis	40.77	0.00e+00	665.00
IUUC-Oni-082639	Oryza nivara	32.70	2.00e-127	449.00
IUUC-Opu-084005	Oryza punctata	41.10	0.00e+00	683.00
IUUC-Oru-084883	Oryza rufipogon	32.47	1.00e-126	447.00
IUUC-Osa-086158	Oryza sativa	40.72	0.00e+00	666.00
IUUC-Ola-086822	Oryzias latipes	70.88	0.00e+00	1329.00
IUUC-Olu-087741	Ostreococcus lucimarinus	32.29	8.00e-20	89.40
IUUC-Oga-088887	Otolemur garnettii	89.39	0.00e+00	1608.00
IUUC-Oar-090110	Ovis aries	86.56	0.00e+00	1552.00
IUUC-Pan-092808	Papio anubis	89.50	0.00e+00	1672.00
IUUC-Psi-093954	Pelodiscus sinensis	76.19	0.00e+00	1442.00
IUUC-Pno-094922	Phaeosphaeria nodorum	51.00	5.00e-178	618.00
IUUC-Ppa-095678	Physcomitrella patens	43.15	0.00e+00	676.00
IUUC-Pfo-097175	Poecilia formosa	71.70	0.00e+00	1356.00
IUUC-Pab-098155	Pongo abelii	89.10	0.00e+00	1672.00
IUUC-Pop-099635	Populus trichocarpa	41.05	0.00e+00	704.00
IUUC-Pca-100947	Procavia capensis	82.34	0.00e+00	1529.00
IUUC-Ppe-101552	Prunus persica	41.74	0.00e+00	721.00
IUUC-Pva-102744	Pteropus vampyrus	79.85	0.00e+00	1460.00
IUUC-Pgr-103389	Puccinia graminis	44.87	0.00e+00	755.00
IUUC-Ptt-103953	Puccinia triticina	39.06	3.00e-174	605.00
IUUC-Pte-104079	Pyrenophora teres	51.42	3.00e-175	608.00
IUUC-Pyt-104656	Pyrenophora triticirepentis	51.86	7.00e-175	607.00
IUUC-Sce-106390	Saccharomyces cerevisiae	44.59	0.00e+00	762.00
IUUC-Sha-107264	Sarcophilus harrisii	74.35	0.00e+00	649.00
IUUC-Sja-107674	Schizosaccharomyces japonicus	42.76	0.00e+00	748.00
IUUC-Spo-108348	Schizosaccharomyces pombe	43.13	0.00e+00	737.00
IUUC-Smo-109327	Selaginella moellendorffii	42.86	0.00e+00	714.00
IUUC-Sit-110304	Setaria italica	41.03	0.00e+00	702.00
IUUC-Sly-111620	Solanum lycopersicum	47.16	3.00e-163	568.00
IUUC-Stu-112877	Solanum tuberosum	41.44	0.00e+00	726.00
IUUC-Sbi-114702	Sorghum bicolor	41.18	0.00e+00	694.00
IUUC-Sre-115129	Sporisorium reilianum	42.55	0.00e+00	704.00
IUUC-Ssc-115931	Sus scrofa	83.76	0.00e+00	702.00
IUUC-Tgu-116787	Taeniopygia guttata	74.94	0.00e+00	1422.00
IUUC-Tru-118218	Takifugu rubripes	69.96	0.00e+00	1320.00
IUUC-Tsy-119401	Tarsius syrichta	87.45	0.00e+00	899.00
IUUC-Tni-120046	Tetraodon nigroviridis	69.10	0.00e+00	1275.00
IUUC-Tca-121685	Theobroma cacao	48.25	2.00e-173	602.00
IUUC-Tre-122154	Trichoderma reesei	44.21	0.00e+00	758.00
IUUC-Tvi-122451	Trichoderma virens	46.51	5.00e-170	591.00
IUUC-Tae-125397	Triticum aestivum	43.92	2.00e-120	426.00
IUUC-Tur-126650	Triticum urartu	39.72	4.00e-178	618.00
IUUC-Tme-127005	Tuber melanosporum	45.69	0.00e+00	771.00
IUUC-Tbe-128102	Tupaia belangeri	91.90	0.00e+00	1000.00
IUUC-Ttr-128259	Tursiops truncatus	86.91	0.00e+00	1544.00
IUUC-Uma-129511	Ustilago maydis	42.89	0.00e+00	699.00
IUUC-Vda-129833	Verticillium dahliae	42.52	0.00e+00	689.00
IUUC-Vvi-131572	Vitis vinifera	41.65	0.00e+00	685.00
IUUC-Xtr-131776	Xenopus tropicalis	55.61	5.00e-118	418.00
IUUC-Xma-133887	Xiphophorus maculatus	72.02	0.00e+00	1313.00
IUUC-Yli-134427	Yarrowia lipolytica	49.83	4.00e-175	608.00
IUUC-Zma-135980	Zea mays	41.45	0.00e+00	689.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence