iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118566

Ensembl Protein ID

ENSTRUP00000008220.1

UniProt Accession

H2S748; H2S748_TAKRU

Protein Name

Uncharacterized protein

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000003500.1	ENSTRUT00000008268.1	ENSTRUP00000008220.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-35	119.2	344	384
UBD/Beta-Prp	6.00e-64	217.3	560	678

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..........sdtl....lvsGsdDgtikvWDl 30
           H++sv++++              l    ++++s D+ti++W++
   Q: 344  HSGSVWSIEVypelsdssqpC--LppssFLTCSSDNTIRLWNV 384
           999*****9559997765540..155559************96 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkl...lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghed 95
           k+ +++++   +++++a +++d+ i+v+dv+tgk+   ++  sg+e++v  ++++p+g++++t+ +D++i ++d+++g+c++tl gh++
   Q: 560  KTTLYDMDLDSSRKHVAIACQDRNIRVYDVETGKMkkcVKGSSGDEGAVIKIQMDPSGSFFATSCSDKNISIFDYESGECISTLFGHSE 648
           56677778888899999999999999999999999666666789999999999999999999999999999999999999999999999 PP
   S: 96   svlslsfspsgdklvsGshdrtirvwdlet 125
            +++l+fs++   l++ s d+ + vw l++
   Q: 649  IATCLRFSQDCRNLITVSGDSCVFVWRLDS 678
           999999999999999999999999998875 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

QVRLEKVLGI TTASGSGLAS DPNTGLVAYP AGCVIVLLHP KKNKQTHIIN TCRRPFSALA 60
FSHDGKYLVT GESGHMPCVR VWEVGGAKVA ETQSHNYGVS HVAFSINSQY IVSVGYQHDM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGTCAGGT TGGAGAAAGT TCTGGGCATC ACCACAGCCA GCGGCAGTGG TTTGGCCTCT 60
GACCCCAACA CGGGCCTGGT TGCTTATCCT GCAGGGTGAG CTCTGCCTCC TCTGAAGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR002469--Peptidase_S9B_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0000922--C:spindle pole
GO:0005682--C:U5 snRNP
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008426	Aspergillus flavus	22.45	2.00e-27	118.00
IUUC-Ani-009489	Aspergillus nidulans	22.49	3.00e-21	97.80
IUUC-Aor-009966	Aspergillus oryzae	22.45	2.00e-27	118.00
IUUC-Ame-010799	Astyanax mexicanus	65.30	0.00e+00	1018.00
IUUC-Cho-024310	Choloepus hoffmanni	52.76	6.00e-159	554.00
IUUC-Dre-028678	Danio rerio	66.28	0.00e+00	1036.00
IUUC-Dse-031501	Dothistroma septosporum	24.16	2.00e-28	121.00
IUUC-Loc-052488	Lepisosteus oculatus	64.16	0.00e+00	1010.00
IUUC-Mtr-058383	Medicago truncatula	32.63	8.00e-55	207.00
IUUC-Ont-072333	Oreochromis niloticus	75.10	0.00e+00	1122.00
IUUC-Pfo-096069	Poecilia formosa	68.01	0.00e+00	1038.00
IUUC-Tni-120316	Tetraodon nigroviridis	81.14	0.00e+00	1104.00
IUUC-Vpa-130392	Vicugna pacos	36.78	1.00e-56	214.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence