iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pte-104355

Ensembl Protein ID

EFQ88961

UniProt Accession

E3RZ70; E3RZ70_PYRTT

Genbank Protein ID

EFQ88961.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

GL536034

Gene Name

PTT_14922

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PTT_14922	EFQ88961	EFQ88961

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.50e-58	197.5	18	554

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagg..lGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           YDRQ+rlwG+++q +l+++++ll++ g+  +G+E+lKnLvl  +g++t+ D + v+ ++l+ +F++++++ g  +Ae +++ lkelnpdv++ +++e+i+ 
   Q: 18   YDRQLRLWGATGQIALEKSHILLINSGPgvVGVETLKNLVLPCIGNFTIQDSAIVTEADLGVNFFLEDRHLGGYRAEHTCNLLKELNPDVDGHFVTEPIES 118
           ************************987666*********************************************************************** PP
   S: 100  leeeivFfkkfdvVvlaldnrear.rkvnrlclnarvpliesgtlGllGqvrviik.gltecyscsd....dppqktiPfctlketpn...........aa 183
             ++   ++ +++++++   r +  +k+     +a vpl+ + + G++ + +v+++  +++ + +++     ++++  P+++l ++ +           ++
   Q: 119  WLTQPDALRPYTLIIATAPIRPEIlTKLSHHASAALVPLFYVHSVGFYAHFSVHLPpAFPIVDTHPNpestSDLRLLRPWPELVQYAEektadldkmkpED 219
           *99977***********998865516899999999*******************972566666666699999*************98888888888989** PP
   S: 184  ehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv..... 274
           + +++w++l+ ++le++++++ ++ + +++ek+e+++ v +++++      eenf+ea+++++k++++ + +s +k+++  +ec  v++++++fwv     
   Q: 220  HGHVPWIALLLHFLEKWKKDHGGEVPQTYKEKTEFRKSVADAARTnnpeGGEENFDEAVAAVLKSLNPPQPSSsVKEIFTAPECLLVREDSPSFWVianai 320
           ********************************************955555579*****************9999*************************** PP
   S: 275  ...................................................................sfcsnaealq........vp............ek 288
                                                                               fc+na+ ++        +             ++
   Q: 321  glfytkynvlpvpgsvpdmkarsadyiqlqnvykskarkdlaeviesvrflernanrstsieekdieVFCKNAAHIKlvrgrpfhIAkagtkikwgdraKS 421
           *******************************************************************8999999988655555551144444444433233 PP
   S: 289  vekdeevvkasap...lylllralerfekkkgrk........pgelsfekdddsavdlvtaaanlra.............eslgiepkldddlikeiagni 365
           +++  +  +   +   ly++++a ++f ++++++         ge++ e       + +t +a  +a              ++++ +    ++++e+++ +
   Q: 422  IAQMLTFPD---SqipLYIAFLAWDEFVATHDKDglagaprvAGECDPET----DSEKLTGIAFKIAddlvkeanasideDQYALIKGQIGEYTRELVRAG 515
           333333333...23357777777777766665542222111123333333....3444444443333444444455555677777664667899******* PP
   S: 366  ipaiattnavvgGlaaqEviKvvsgkfeplknfflfdae 404
            ++++ + a  gG+++qE+iK+++++++p++n+ +fd++
   Q: 516  GAELHNIGALTGGIVSQEIIKAITEQYVPVDNTCVFDGI 554
           ************************************985 PP

Organism

Pyrenophora teres

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MEDLPPPVQG PTAKEKKYDR QLRLWGATGQ IALEKSHILL INSGPGVVGV ETLKNLVLPC 60
IGNFTIQDSA IVTEADLGVN FFLEDRHLGG YRAEHTCNLL KELNPDVDGH FVTEPIESWL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGATC TTCCCCCTCC CGTCCAGGGC CCGACTGCAA AGGAGAAGAA GTAGGTGTGC 60
ACATGAACAA AGTATGGGAC GATGAGCTGA TCCAAGCAGA TATGATCGTC AACTACGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

pte:PTT_14922

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	33.09	1.00e-71	262.00
IUUC-Aml-002333	Ailuropoda melanoleuca	36.41	3.00e-90	323.00
IUUC-Atr-002644	Amborella trichopoda	33.57	6.00e-67	246.00
IUUC-Apl-003446	Anas platyrhynchos	35.21	1.00e-80	291.00
IUUC-Aca-004450	Anolis carolinensis	32.32	1.00e-81	295.00
IUUC-Aly-005466	Arabidopsis lyrata	33.09	3.00e-75	273.00
IUUC-Ath-006692	Arabidopsis thaliana	33.09	2.00e-76	278.00
IUUC-Ago-007900	Ashbya gossypii	27.27	2.00e-27	115.00
IUUC-Acl-008333	Aspergillus clavatus	50.96	2.00e-151	527.00
IUUC-Afl-008529	Aspergillus flavus	52.53	2.00e-154	537.00
IUUC-Afu-009071	Aspergillus fumigatus	50.26	1.00e-149	521.00
IUUC-Ani-009443	Aspergillus nidulans	49.48	1.00e-143	501.00
IUUC-Ang-009669	Aspergillus niger	50.87	8.00e-158	548.00
IUUC-Aor-009914	Aspergillus oryzae	51.90	4.00e-153	533.00
IUUC-Ate-010450	Aspergillus terreus	50.69	4.00e-152	529.00
IUUC-Ame-011183	Astyanax mexicanus	35.36	1.00e-86	312.00
IUUC-Bgr-012111	Blumeria graminis	43.47	9.00e-122	428.00
IUUC-Bta-012583	Bos taurus	35.77	2.00e-91	328.00
IUUC-Bci-013892	Botrytis cinerea	48.07	4.00e-137	479.00
IUUC-Bdi-014592	Brachypodium distachyon	33.63	1.00e-69	255.00
IUUC-Bol-015487	Brassica oleracea	34.88	6.00e-77	279.00
IUUC-Bra-017506	Brassica rapa	34.49	6.00e-76	276.00
IUUC-Cel-018456	Caenorhabditis elegans	31.21	3.00e-60	224.00
IUUC-Cja-020007	Callithrix jacchus	35.99	1.00e-90	325.00
IUUC-Cfa-020324	Canis familiaris	36.36	2.00e-92	331.00
IUUC-Cpo-022248	Cavia porcellus	35.06	3.00e-50	190.00
IUUC-Csa-023149	Chlorocebus sabaeus	33.75	1.00e-67	249.00
IUUC-Cho-024537	Choloepus hoffmanni	28.83	1.00e-49	189.00
IUUC-Cin-025763	Ciona intestinalis	33.33	2.00e-81	294.00
IUUC-Csv-026113	Ciona savignyi	32.57	2.00e-79	288.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	42.14	6.00e-110	389.00
IUUC-Cne-026884	Cryptococcus neoformans	30.19	9.00e-57	213.00
IUUC-Cme-027210	Cyanidioschyzon merolae	19.42	7.00e-17	80.50
IUUC-Dre-028140	Danio rerio	36.38	8.00e-89	319.00
IUUC-Dno-030033	Dasypus novemcinctus	38.31	8.00e-81	292.00
IUUC-Dor-030513	Dipodomys ordii	52.78	8.00e-24	103.00
IUUC-Dse-031536	Dothistroma septosporum	55.46	0.00e+00	645.00
IUUC-Dme-031683	Drosophila melanogaster	32.55	3.00e-76	277.00
IUUC-Ete-032420	Echinops telfairi	31.87	1.00e-70	258.00
IUUC-Eca-033992	Equus caballus	33.05	1.00e-65	241.00
IUUC-Eeu-034713	Erinaceus europaeus	55.45	7.00e-25	107.00
IUUC-Fca-036548	Felis catus	36.19	1.00e-90	325.00
IUUC-Fal-037600	Ficedula albicollis	34.85	3.00e-79	287.00
IUUC-Fox-038037	Fusarium oxysporum	41.64	3.00e-129	453.00
IUUC-Fso-038387	Fusarium solani	42.96	6.00e-130	456.00
IUUC-Gmo-038562	Gadus morhua	34.35	1.00e-85	308.00
IUUC-Ggr-040005	Gaeumannomyces graminis	46.76	4.00e-134	469.00
IUUC-Gga-041129	Gallus gallus	35.17	4.00e-86	310.00
IUUC-Gac-042558	Gasterosteus aculeatus	34.10	2.00e-83	301.00
IUUC-Gma-043610	Glycine max	33.51	3.00e-73	267.00
IUUC-Ggo-045611	Gorilla gorilla	36.46	5.00e-90	323.00
IUUC-Hsa-046563	Homo sapiens	36.77	3.00e-91	327.00
IUUC-Hvu-047790	Hordeum vulgare	30.00	2.00e-40	158.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	36.19	9.00e-91	325.00
IUUC-Kpa-049309	Komagataella pastoris	32.07	6.00e-68	249.00
IUUC-Lch-050038	Latimeria chalumnae	35.28	8.00e-85	306.00
IUUC-Lpe-051535	Leersia perrieri	31.33	9.00e-54	202.00
IUUC-Loc-051917	Lepisosteus oculatus	34.32	1.00e-81	295.00
IUUC-Lma-053112	Leptosphaeria maculans	79.93	0.00e+00	958.00
IUUC-Laf-053690	Loxodonta africana	36.36	3.00e-91	327.00
IUUC-Mcc-055117	Macaca mulatta	35.58	5.00e-87	313.00
IUUC-Meu-056761	Macropus eugenii	28.92	2.00e-59	222.00
IUUC-Mor-057230	Magnaporthe oryzae	45.66	3.00e-133	466.00
IUUC-Mpo-057514	Magnaporthe poae	47.15	3.00e-129	453.00
IUUC-Mtr-058551	Medicago truncatula	32.33	4.00e-68	250.00
IUUC-Mla-059183	Melampsora laricipopulina	32.43	5.00e-79	286.00
IUUC-Mga-060144	Meleagris gallopavo	34.71	8.00e-82	295.00
IUUC-Mvi-060221	Microbotryum violaceum	39.05	2.00e-67	248.00
IUUC-Mmr-061325	Microcebus murinus	35.64	1.00e-86	311.00
IUUC-Mdo-062532	Monodelphis domestica	35.05	3.00e-87	313.00
IUUC-Mmu-063956	Mus musculus	36.19	4.00e-92	330.00
IUUC-Mac-064521	Musa acuminata	33.99	1.00e-69	255.00
IUUC-Mpu-066716	Mustela putorius furo	35.73	7.00e-82	296.00
IUUC-Mlu-067459	Myotis lucifugus	36.81	7.00e-93	332.00
IUUC-Nfi-068245	Neosartorya fischeri	50.87	8.00e-152	528.00
IUUC-Ncr-068910	Neurospora crassa	46.21	5.00e-146	509.00
IUUC-Nle-070034	Nomascus leucogenys	34.85	3.00e-83	300.00
IUUC-Opr-070552	Ochotona princeps	33.90	1.00e-72	265.00
IUUC-Ont-071426	Oreochromis niloticus	35.55	2.00e-87	315.00
IUUC-Oan-073389	Ornithorhynchus anatinus	32.14	7.00e-60	222.00
IUUC-Ocu-074911	Oryctolagus cuniculus	36.19	3.00e-90	324.00
IUUC-Oba-075437	Oryza barthii	32.13	9.00e-62	229.00
IUUC-Obr-076684	Oryza brachyantha	32.55	3.00e-58	218.00
IUUC-Ogl-077170	Oryza glaberrima	32.13	9.00e-62	229.00
IUUC-Ogu-078844	Oryza glumaepatula	31.51	4.00e-55	207.00
IUUC-Oin-079105	Oryza indica	32.07	7.00e-62	229.00
IUUC-Olo-080943	Oryza longistaminata	29.48	8.00e-49	186.00
IUUC-Oni-082891	Oryza nivara	29.89	2.00e-55	208.00
IUUC-Opu-083457	Oryza punctata	32.31	3.00e-61	227.00
IUUC-Oru-084960	Oryza rufipogon	29.48	5.00e-49	186.00
IUUC-Osa-085358	Oryza sativa	32.07	9.00e-62	229.00
IUUC-Ola-086420	Oryzias latipes	33.67	6.00e-57	212.00
IUUC-Olu-087625	Ostreococcus lucimarinus	29.02	8.00e-48	182.00
IUUC-Oga-088810	Otolemur garnettii	35.59	5.00e-92	330.00
IUUC-Oar-089196	Ovis aries	35.22	2.00e-89	321.00
IUUC-Ptr-090617	Pan troglodytes	36.48	7.00e-91	326.00
IUUC-Pan-092761	Papio anubis	36.54	4.00e-92	330.00
IUUC-Psi-093191	Pelodiscus sinensis	33.88	7.00e-81	292.00
IUUC-Pma-094380	Petromyzon marinus	32.76	4.00e-70	256.00
IUUC-Pno-095084	Phaeosphaeria nodorum	75.84	0.00e+00	879.00
IUUC-Ppa-095875	Physcomitrella patens	32.62	8.00e-70	256.00
IUUC-Pfo-096467	Poecilia formosa	34.52	3.00e-87	314.00
IUUC-Pab-098255	Pongo abelii	37.86	1.00e-80	291.00
IUUC-Pop-099871	Populus trichocarpa	32.85	3.00e-73	267.00
IUUC-Pca-100807	Procavia capensis	37.06	2.00e-27	114.00
IUUC-Ppe-101280	Prunus persica	33.57	2.00e-73	268.00
IUUC-Pva-102333	Pteropus vampyrus	35.35	6.00e-84	303.00
IUUC-Pgr-103401	Puccinia graminis	29.29	1.00e-62	232.00
IUUC-Ptt-103889	Puccinia triticina	27.74	7.00e-57	213.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	95.56	0.00e+00	1112.00
IUUC-Rno-105810	Rattus norvegicus	35.94	5.00e-91	326.00
IUUC-Sce-106397	Saccharomyces cerevisiae	25.43	1.00e-21	95.90
IUUC-Sha-106770	Sarcophilus harrisii	40.00	5.00e-52	196.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	29.48	3.00e-62	231.00
IUUC-Spo-108276	Schizosaccharomyces pombe	30.40	5.00e-70	256.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	48.59	1.00e-141	494.00
IUUC-Smo-109296	Selaginella moellendorffii	33.45	7.00e-75	273.00
IUUC-Sit-110157	Setaria italica	32.79	2.00e-70	258.00
IUUC-Sly-111105	Solanum lycopersicum	31.73	2.00e-71	261.00
IUUC-Stu-112469	Solanum tuberosum	32.09	3.00e-73	267.00
IUUC-Sar-113083	Sorex araneus	27.32	3.00e-48	184.00
IUUC-Sbi-113813	Sorghum bicolor	33.82	1.00e-72	265.00
IUUC-Sre-115058	Sporisorium reilianum	33.81	7.00e-78	283.00
IUUC-Tgu-116772	Taeniopygia guttata	33.87	8.00e-79	285.00
IUUC-Tru-118686	Takifugu rubripes	35.06	4.00e-87	313.00
IUUC-Tsy-119111	Tarsius syrichta	37.85	2.00e-44	172.00
IUUC-Tni-120231	Tetraodon nigroviridis	32.50	2.00e-76	278.00
IUUC-Tca-121491	Theobroma cacao	32.97	7.00e-69	253.00
IUUC-Tre-122103	Trichoderma reesei	45.21	1.00e-135	474.00
IUUC-Tvi-122672	Trichoderma virens	45.04	3.00e-132	463.00
IUUC-Tae-125684	Triticum aestivum	33.09	4.00e-72	263.00
IUUC-Tur-126487	Triticum urartu	32.12	6.00e-67	246.00
IUUC-Tme-127097	Tuber melanosporum	39.65	2.00e-99	354.00
IUUC-Ttr-128465	Tursiops truncatus	33.87	1.00e-76	279.00
IUUC-Uma-129645	Ustilago maydis	34.72	1.00e-80	292.00
IUUC-Vda-129989	Verticillium dahliae	41.83	2.00e-104	370.00
IUUC-Vpa-130529	Vicugna pacos	34.75	2.00e-80	291.00
IUUC-Vvi-131059	Vitis vinifera	33.15	7.00e-72	263.00
IUUC-Xtr-132002	Xenopus tropicalis	36.59	5.00e-90	323.00
IUUC-Xma-133930	Xiphophorus maculatus	35.05	2.00e-85	308.00
IUUC-Yli-134505	Yarrowia lipolytica	35.60	4.00e-81	293.00
IUUC-Zma-135619	Zea mays	33.15	4.00e-69	253.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence