iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051800

Ensembl Protein ID

ENSLOCP00000013174.1

UniProt Accession

W5MXR5; W5MXR5_LEPOC

Genbank Protein ID

ENSLOCP00000013174

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01031677

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000010739.1	ENSLOCT00000013202.1	ENSLOCP00000013174.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.90e-115	383.8	320	1002
ULD/UDP/UBQ/UBQ_Other	5.70e-12	45.5	161	238

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+NlgNtC+mNS+LQcLsn  +l+e++l+ +++ ++n+enp ++ ge+++++++l++++w++++++v+pr+++++++++a++fsg
   Q: 320  CGLSNLGNTCFMNSALQCLSNAAPLTEYFLKdEYEAEINRENPLGMRGEIAEAYADLVKQMWQGRNSYVAPRTFKTQVGRFAPQFSG 406
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+qqD+qE+laflld+l+e+l++ k+kp+  +++++   ++de     a+ ++  +n+s+i+d+F+g +ks+++c+ec +vs++++p
   Q: 407  YQQQDSQELLAFLLDGLHEDLNRVKKKPYLVLRDAE--GRQDEivakeAWTNHRLRNDSIIVDIFHGLFKSTLVCPECSKVSVTFDP 491
           ****************************98887666..5555555666*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f++l+lp+p+k+++ +e                                                                      
   Q: 492  FCYLTLPLPMKKDRTMEvflvrtdpqsrpmqyrvvvpklgtvadlcsslsklsgvtaenmlvadvynhrfhkiyrrddglnhimdkd 578
           ************99999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 579  difvyeveeedgerislpiyfrerhvkhagtststvlfgqpliitvprqnlavdflyekvlerigryvkrpqgagcegkvsatcsss 665
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 666  sscsssqaaemaggrslntemgasvcqsleeascsagtagmvtsncqnakhqpgtcnsnnsngvcegedeamdhqeeislepdnsqs 752
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 753  egsvgdedsedlengpvdnapkssvksttcqpklfsftmvnsygtadispvtnesnilklkafstvaidwnsemkklyyddqeaeay 839
           *************************************************************************************** PP
   S: 186  ................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefp 256
                            l+dc+e ft+ e+l +++ +yc++ckk+q+a+kk++l++lP++L++hLkRfs+++  + r k+++ v+fp
   Q: 840  ekhesmlqhqrkkatvALRDCIELFTTMETLGEHDPWYCPTCKKHQQATKKFDLWSLPRILVVHLKRFSYNR--CWRDKLDTVVDFP 924
           ********************************************************************9966..6778********* PP
   S: 257  le.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           ++ L++s+f+++p+ +   +++Y+Liav +H+G++++GHY+ay+kn  +g+W++fdDs+V++ +e+++++   + aYvlfY+rr
   Q: 925  ISdLNMSEFVCDPKAG---PYIYDLIAVSNHYGGMGGGHYTAYAKNkVDGQWYYFDDSSVSSATEDQIVT---KAAYVLFYQRR 1002
           ************9987...8**************************44677*******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 6    ksldgs.eltlkvnpsdtVaeLKekiekklgippe.qqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           +++d   + t++++++dt+ ++ ++++ +++ippe + rL++k      + L ++  t++d gl++g+++++++k+++
   Q: 161  ENSDMDnVITRHFSKADTIETIEKEMRVLFKIPPEkETRLWNKymsntYEQLnKPESTVQDAGLYQGQVLVIEQKNED 238
           55555558899**********************555*****999987744457*********************9986 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

TMAEGGGPES GSGTEPDPEP VPAQIPLPSP DSQKQSLGAL LKTPLRKGDE WFLIDSRWFK 60
QWKKYVGFDS WDMYNVGEFS LYPGPIDNSG LFSDHETQTL KEHLIDELDY VLVPTEAWNK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGATGGCTG AGGGAGGAGG ACCCGAATCG GGTAGCGGGA CTGAACCCGA TCCGGAGCCG 60
GTACCTGCTC AGATACCCTT ACCTTCACCC GACAGCCAGA AGCAAAGCCT AGGAGCTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0034122--P:negative regulation of toll-like receptor signaling pathway
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002991	Amborella trichopoda	38.36	3.00e-99	356.00
IUUC-Apl-004068	Anas platyrhynchos	60.26	0.00e+00	1099.00
IUUC-Ago-007911	Ashbya gossypii	41.90	1.00e-64	241.00
IUUC-Ani-009479	Aspergillus nidulans	36.44	2.00e-53	204.00
IUUC-Ang-009562	Aspergillus niger	38.03	4.00e-57	217.00
IUUC-Aor-009949	Aspergillus oryzae	35.85	7.00e-56	212.00
IUUC-Ate-010323	Aspergillus terreus	37.59	5.00e-59	223.00
IUUC-Ame-011064	Astyanax mexicanus	74.55	0.00e+00	1068.00
IUUC-Bta-012929	Bos taurus	65.10	0.00e+00	1268.00
IUUC-Bdi-015062	Brachypodium distachyon	39.77	1.00e-125	444.00
IUUC-Bra-017029	Brassica rapa	39.05	7.00e-108	385.00
IUUC-Cpo-022144	Cavia porcellus	65.21	0.00e+00	1235.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	35.47	3.00e-62	234.00
IUUC-Cne-026852	Cryptococcus neoformans	38.78	1.00e-70	262.00
IUUC-Cme-027338	Cyanidioschyzon merolae	57.58	2.00e-66	247.00
IUUC-Dre-027869	Danio rerio	78.78	0.00e+00	1502.00
IUUC-Dse-031432	Dothistroma septosporum	36.10	5.00e-59	223.00
IUUC-Fal-037634	Ficedula albicollis	64.43	0.00e+00	1189.00
IUUC-Gmo-038866	Gadus morhua	81.62	0.00e+00	966.00
IUUC-Gga-040729	Gallus gallus	59.58	0.00e+00	1132.00
IUUC-Gac-042631	Gasterosteus aculeatus	85.67	0.00e+00	1093.00
IUUC-Ggo-045337	Gorilla gorilla	65.49	0.00e+00	1130.00
IUUC-Hsa-045669	Homo sapiens	66.57	0.00e+00	1253.00
IUUC-Lch-050533	Latimeria chalumnae	69.55	0.00e+00	1222.00
IUUC-Mor-056985	Magnaporthe oryzae	39.48	8.00e-62	233.00
IUUC-Mla-058848	Melampsora laricipopulina	35.36	4.00e-101	363.00
IUUC-Mga-059300	Meleagris gallopavo	59.51	0.00e+00	1097.00
IUUC-Mvi-060324	Microbotryum violaceum	47.21	4.00e-72	266.00
IUUC-Nle-070010	Nomascus leucogenys	66.02	0.00e+00	1250.00
IUUC-Ont-072573	Oreochromis niloticus	77.54	0.00e+00	1526.00
IUUC-Oan-073363	Ornithorhynchus anatinus	63.99	0.00e+00	859.00
IUUC-Obr-076410	Oryza brachyantha	38.24	2.00e-121	429.00
IUUC-Ola-086553	Oryzias latipes	83.41	0.00e+00	1080.00
IUUC-Oar-090439	Ovis aries	65.79	0.00e+00	1261.00
IUUC-Ptr-090801	Pan troglodytes	66.67	0.00e+00	1256.00
IUUC-Psi-093942	Pelodiscus sinensis	63.84	0.00e+00	1170.00
IUUC-Pfo-097060	Poecilia formosa	75.52	0.00e+00	1488.00
IUUC-Pca-100161	Procavia capensis	70.61	0.00e+00	854.00
IUUC-Ptt-103847	Puccinia triticina	36.01	6.00e-61	229.00
IUUC-Sce-106170	Saccharomyces cerevisiae	37.81	4.00e-61	230.00
IUUC-Spo-108291	Schizosaccharomyces pombe	42.81	4.00e-73	269.00
IUUC-Sly-111746	Solanum lycopersicum	38.43	2.00e-108	387.00
IUUC-Stu-112671	Solanum tuberosum	37.79	2.00e-106	380.00
IUUC-Sre-115130	Sporisorium reilianum	47.97	2.00e-76	281.00
IUUC-Ssc-115637	Sus scrofa	71.54	0.00e+00	924.00
IUUC-Tgu-117267	Taeniopygia guttata	63.39	0.00e+00	1179.00
IUUC-Tca-121001	Theobroma cacao	39.70	2.00e-107	383.00
IUUC-Tvi-122422	Trichoderma virens	35.47	7.00e-58	219.00
IUUC-Tae-123874	Triticum aestivum	39.02	8.00e-123	434.00
IUUC-Xtr-132305	Xenopus tropicalis	66.33	0.00e+00	1268.00
IUUC-Xma-133176	Xiphophorus maculatus	75.29	0.00e+00	1358.00
IUUC-Yli-134392	Yarrowia lipolytica	44.24	5.00e-62	233.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence