iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ppa-095638

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

DS545132

Gene Name

PHYPADRAFT_146433

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S243_63V6	PP1S243_63V6.1	PP1S243_63V6.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.50e-36	121.2	184	224
UBD/Beta-Prp	2.90e-69	234.3	14	286

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+ +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 184  HQKGVNCVEYftgGDrPHLITGSDDQTAKVWDYQTKSCVQT 224
           9999****966*9778*******************999986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
           ++++++cv+ +p +++++++ ++g++ +w++++++l++s++  + +v++ kf+p+++++v gs+D++i+v++++t + v  +++h+d+++++ ++
   Q: 14   RSERVKCVDLHPTEPWILSTLYSGSVYIWNYQNQTLVKSFEVTDLPVRSAKFIPRKQWIVAGSDDMFIRVYNYNTMDKVKQFEAHTDYIRCVVVH 108
           67789****************************************************************************************** PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkel 195
           p+ ++++s s+d  i++wd+e+g+   ++++gh++ v+ v+++p++ n ++s+slDrtv++W+l + +   tl+  h++ v++++     ++++l
   Q: 109  PTLSYVLSCSDDMLIKLWDWEKGWICTQIFEGHSHYVMQVTFNPKDsNTFASASLDRTVKIWNLGSPEPNFTLEA-HQKGVNCVEyfTGGDRPHL 202
           ************************9999*********************************************98.*********7445566*** PP
   S: 196  vsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnv 279
           ++gs+d+t k+wd+qt++cv+tl+gh+ nv+ v f+p+  ++++gs+Dg++riW  ++  l +tl++  ++v+++ +++ ++++
   Q: 203  ITGSDDQTAKVWDYQTKSCVQTLEGHSHNVSAVCFHPELPIILTGSEDGTVRIWHATTYRLENTLNYGLERVWAIGYIKGSKRI 286
           **************************************************************************9985444443 PP

Organism

Physcomitrella patens

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLAIKRK LAQRSERVKC VDLHPTEPWI LSTLYSGSVY IWNYQNQTLV KSFEVTDLPV 60
RSAKFIPRKQ WIVAGSDDMF IRVYNYNTMD KVKQFEAHTD YIRCVVVHPT LSYVLSCSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCGTTGCC CTCCTCCGTC CTAGCCCTCC TCCTCCGTCC TAGCCCTCCT CCTCCGAGCT 60
CGTGGTGGTG GTGGTGGTGG TGTTCCCCGG AGATCCTTCC GCTTGCTGTT GCTTCGTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0732--Signal
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

ppp:PHYPADRAFT_146433

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006508	Arabidopsis lyrata	77.18	0.00e+00	1378.00
IUUC-Ago-007914	Ashbya gossypii	46.92	0.00e+00	727.00
IUUC-Acl-008237	Aspergillus clavatus	53.93	0.00e+00	919.00
IUUC-Afl-008535	Aspergillus flavus	52.76	0.00e+00	872.00
IUUC-Afu-008845	Aspergillus fumigatus	54.30	0.00e+00	906.00
IUUC-Ani-009135	Aspergillus nidulans	53.51	0.00e+00	889.00
IUUC-Aor-009939	Aspergillus oryzae	53.51	0.00e+00	928.00
IUUC-Ate-010355	Aspergillus terreus	53.93	0.00e+00	894.00
IUUC-Bgr-012249	Blumeria graminis	53.44	0.00e+00	891.00
IUUC-Bol-015731	Brassica oleracea	76.79	0.00e+00	1384.00
IUUC-Bra-017758	Brassica rapa	77.02	0.00e+00	1380.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	51.30	0.00e+00	800.00
IUUC-Dse-031268	Dothistroma septosporum	53.14	0.00e+00	882.00
IUUC-Fox-037711	Fusarium oxysporum	55.14	0.00e+00	845.00
IUUC-Fso-038268	Fusarium solani	54.75	0.00e+00	848.00
IUUC-Hvu-047669	Hordeum vulgare	87.01	0.00e+00	667.00
IUUC-Nfi-068277	Neosartorya fischeri	54.26	0.00e+00	898.00
IUUC-Ncr-068659	Neurospora crassa	54.76	0.00e+00	904.00
IUUC-Pno-094785	Phaeosphaeria nodorum	58.76	1.00e-103	369.00
IUUC-Sce-106269	Saccharomyces cerevisiae	48.61	0.00e+00	764.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	47.41	0.00e+00	778.00
IUUC-Spo-108299	Schizosaccharomyces pombe	46.84	0.00e+00	787.00
IUUC-Vda-129716	Verticillium dahliae	55.14	0.00e+00	915.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence