iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pop-099992

Ensembl Protein ID

POPTR_0015s08110.1

UniProt Accession

B9IEK6; B9IEK6_POPTR

Genbank Protein ID

EEF05685.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CM000351

Gene Name

POPTRDRAFT_575095; POPTR_0015s08110g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
POPTR_0015s08110	POPTR_0015s08110.1	POPTR_0015s08110.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-38	128.6	50	85
UBD/Beta-Prp	1.80e-75	255.0	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f  s +l+vsG+dD +ikvW+++ +++
   Q: 50   HDGPVRGVHFhkSQPLFVSGGDDYKIKVWNYKLHRC 85
           99*********7559***************876666 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           t +++++++++ + f+ ++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++   c+ tl gh 
   Q: 3    TKFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFHKSQPLFVSGGDDYKIKVWNYKLHRCLFTLLGHL 93
           67889999*********************************************************************************** PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl................... 166
           d++++++f+ +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                   
   Q: 94   DYIRTVQFHHEYPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgalrkktvspaddimrltq 183
           ************************************.********************************************9999998887 PP
   S: 167  ........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsir 247
                     + + + l+g h++ v++ +f+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+sir
   Q: 184  mnsdlfggVDAVVKYVLEG-HDRGVNWAAFHPTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIR 273
           7777777444444444466.********************************777668********************************* PP
   S: 248  iWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           +Wd+++++ ++t+ +++++++  a  +++ n l++g  ds   ++kl++++p
   Q: 274  VWDVTKRTGVQTFRREHDRFWILAS-HPEMNLLAAG-HDSGMIVFKLERERP 323
           ************************9.6666655555.689999999988765 PP

Organism

Populus trichocarpa

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHSK RPWILASLHS GVIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
KSQPLFVSGG DDYKIKVWNY KLHRCLFTLL GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCGACGAG ACCCAGATCT AAAGTTCCAT AATAATAAAG AGAGAGCCCC GCTCCCAAAA 60
AAAATAAATA AAAGGAAAGG AAAAGGAAAA AATTTCTCTC CCCCATCTAG CTCTCTTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

pop:POPTR_0015s08110g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001758	Ailuropoda melanoleuca	56.17	0.00e+00	1395.00
IUUC-Atr-002493	Amborella trichopoda	84.32	0.00e+00	2063.00
IUUC-Apl-003385	Anas platyrhynchos	50.79	0.00e+00	1079.00
IUUC-Aca-005154	Anolis carolinensis	80.39	3.00e-97	346.00
IUUC-Aly-006020	Arabidopsis lyrata	85.25	0.00e+00	2108.00
IUUC-Ath-007058	Arabidopsis thaliana	85.15	0.00e+00	2101.00
IUUC-Ago-007992	Ashbya gossypii	43.60	0.00e+00	974.00
IUUC-Acl-008027	Aspergillus clavatus	55.73	0.00e+00	976.00
IUUC-Afl-008644	Aspergillus flavus	55.70	0.00e+00	970.00
IUUC-Afu-008964	Aspergillus fumigatus	48.26	0.00e+00	1135.00
IUUC-Ani-009379	Aspergillus nidulans	56.01	0.00e+00	988.00
IUUC-Ang-009756	Aspergillus niger	48.13	0.00e+00	1134.00
IUUC-Aor-010174	Aspergillus oryzae	55.70	0.00e+00	970.00
IUUC-Ate-010302	Aspergillus terreus	48.19	0.00e+00	1169.00
IUUC-Ame-011229	Astyanax mexicanus	55.34	0.00e+00	1373.00
IUUC-Bgr-012300	Blumeria graminis	47.85	0.00e+00	1103.00
IUUC-Bta-012524	Bos taurus	56.66	0.00e+00	1388.00
IUUC-Bci-013781	Botrytis cinerea	47.97	0.00e+00	1136.00
IUUC-Bdi-014549	Brachypodium distachyon	78.85	0.00e+00	2042.00
IUUC-Bol-015925	Brassica oleracea	83.55	0.00e+00	2068.00
IUUC-Bra-016978	Brassica rapa	84.36	0.00e+00	2080.00
IUUC-Cel-018115	Caenorhabditis elegans	55.37	0.00e+00	945.00
IUUC-Cja-019107	Callithrix jacchus	55.70	0.00e+00	1377.00
IUUC-Cfa-020675	Canis familiaris	55.86	0.00e+00	1368.00
IUUC-Cpo-021813	Cavia porcellus	56.74	0.00e+00	1406.00
IUUC-Csa-023523	Chlorocebus sabaeus	56.74	0.00e+00	1409.00
IUUC-Cho-024704	Choloepus hoffmanni	42.59	1.00e-178	620.00
IUUC-Cin-025572	Ciona intestinalis	51.69	0.00e+00	1275.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	55.92	0.00e+00	989.00
IUUC-Cne-027053	Cryptococcus neoformans	51.42	0.00e+00	1209.00
IUUC-Dre-027421	Danio rerio	55.96	0.00e+00	1390.00
IUUC-Dno-029303	Dasypus novemcinctus	56.79	0.00e+00	1413.00
IUUC-Dse-031543	Dothistroma septosporum	47.17	0.00e+00	1094.00
IUUC-Dme-031945	Drosophila melanogaster	60.91	0.00e+00	1042.00
IUUC-Eca-033773	Equus caballus	55.81	0.00e+00	1368.00
IUUC-Eeu-034874	Erinaceus europaeus	42.78	0.00e+00	687.00
IUUC-Fca-035739	Felis catus	55.63	0.00e+00	1360.00
IUUC-Fal-037263	Ficedula albicollis	52.64	0.00e+00	1239.00
IUUC-Fox-037738	Fusarium oxysporum	48.29	0.00e+00	1159.00
IUUC-Fso-038153	Fusarium solani	48.21	0.00e+00	1146.00
IUUC-Gmo-039602	Gadus morhua	52.79	0.00e+00	1281.00
IUUC-Ggr-039931	Gaeumannomyces graminis	55.40	0.00e+00	972.00
IUUC-Gga-040590	Gallus gallus	56.02	0.00e+00	1408.00
IUUC-Gac-041318	Gasterosteus aculeatus	55.42	0.00e+00	1392.00
IUUC-Gma-043257	Glycine max	87.23	0.00e+00	2168.00
IUUC-Ggo-045029	Gorilla gorilla	56.33	0.00e+00	1401.00
IUUC-Hsa-046078	Homo sapiens	56.33	0.00e+00	1401.00
IUUC-Hvu-047556	Hordeum vulgare	79.84	0.00e+00	2050.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	47.94	0.00e+00	788.00
IUUC-Kpa-049256	Komagataella pastoris	45.54	0.00e+00	1056.00
IUUC-Lch-049706	Latimeria chalumnae	55.64	0.00e+00	1391.00
IUUC-Lma-053138	Leptosphaeria maculans	55.54	0.00e+00	991.00
IUUC-Laf-053510	Loxodonta africana	56.79	0.00e+00	1429.00
IUUC-Mcc-055836	Macaca mulatta	56.34	0.00e+00	1397.00
IUUC-Mor-057172	Magnaporthe oryzae	47.61	0.00e+00	1127.00
IUUC-Mpo-057300	Magnaporthe poae	48.60	0.00e+00	1133.00
IUUC-Mtr-058423	Medicago truncatula	84.65	0.00e+00	2053.00
IUUC-Mla-059019	Melampsora laricipopulina	51.66	0.00e+00	1249.00
IUUC-Mga-059499	Meleagris gallopavo	55.93	0.00e+00	1405.00
IUUC-Mvi-060336	Microbotryum violaceum	51.46	0.00e+00	1229.00
IUUC-Mmr-061102	Microcebus murinus	55.73	0.00e+00	1380.00
IUUC-Mdo-062594	Monodelphis domestica	57.30	0.00e+00	1431.00
IUUC-Mmu-063736	Mus musculus	56.25	0.00e+00	1397.00
IUUC-Mpu-066701	Mustela putorius furo	56.07	0.00e+00	1410.00
IUUC-Mlu-067392	Myotis lucifugus	56.90	0.00e+00	1399.00
IUUC-Nfi-068270	Neosartorya fischeri	55.84	0.00e+00	975.00
IUUC-Opr-070952	Ochotona princeps	42.37	0.00e+00	663.00
IUUC-Ont-072488	Oreochromis niloticus	55.10	0.00e+00	1372.00
IUUC-Ocu-074211	Oryctolagus cuniculus	56.58	0.00e+00	1400.00
IUUC-Ola-086921	Oryzias latipes	53.75	0.00e+00	1343.00
IUUC-Olu-087639	Ostreococcus lucimarinus	62.53	0.00e+00	1580.00
IUUC-Oga-087991	Otolemur garnettii	53.47	0.00e+00	1303.00
IUUC-Oar-089590	Ovis aries	56.58	0.00e+00	1404.00
IUUC-Ptr-090808	Pan troglodytes	56.41	0.00e+00	1402.00
IUUC-Pan-092475	Papio anubis	56.61	0.00e+00	1403.00
IUUC-Pno-094839	Phaeosphaeria nodorum	54.51	0.00e+00	922.00
IUUC-Ppa-095254	Physcomitrella patens	71.58	0.00e+00	1820.00
IUUC-Pfo-097493	Poecilia formosa	55.83	0.00e+00	1374.00
IUUC-Pab-098497	Pongo abelii	56.74	0.00e+00	1411.00
IUUC-Ppe-101899	Prunus persica	89.98	0.00e+00	2212.00
IUUC-Pva-102126	Pteropus vampyrus	54.17	0.00e+00	1325.00
IUUC-Pgr-103376	Puccinia graminis	51.58	0.00e+00	1251.00
IUUC-Pte-104126	Pyrenophora teres	55.14	0.00e+00	949.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	45.99	1.00e-178	620.00
IUUC-Rno-105428	Rattus norvegicus	56.50	0.00e+00	1402.00
IUUC-Sce-106464	Saccharomyces cerevisiae	42.43	0.00e+00	951.00
IUUC-Sha-107301	Sarcophilus harrisii	56.12	0.00e+00	1382.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	45.54	0.00e+00	1085.00
IUUC-Spo-108217	Schizosaccharomyces pombe	45.68	0.00e+00	1067.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	47.97	0.00e+00	1140.00
IUUC-Smo-108819	Selaginella moellendorffii	68.06	0.00e+00	1744.00
IUUC-Sly-111759	Solanum lycopersicum	85.06	0.00e+00	2183.00
IUUC-Stu-112564	Solanum tuberosum	84.81	0.00e+00	2169.00
IUUC-Sar-113313	Sorex araneus	43.24	0.00e+00	664.00
IUUC-Sre-115209	Sporisorium reilianum	54.69	0.00e+00	1011.00
IUUC-Ssc-115933	Sus scrofa	56.66	0.00e+00	1404.00
IUUC-Tgu-117109	Taeniopygia guttata	44.79	2.00e-113	402.00
IUUC-Tru-117772	Takifugu rubripes	54.29	0.00e+00	1341.00
IUUC-Tsy-119105	Tarsius syrichta	54.07	0.00e+00	1077.00
IUUC-Tni-120556	Tetraodon nigroviridis	40.17	0.00e+00	816.00
IUUC-Tca-121545	Theobroma cacao	89.50	0.00e+00	2227.00
IUUC-Tre-121951	Trichoderma reesei	47.45	0.00e+00	1118.00
IUUC-Tvi-122359	Trichoderma virens	56.01	0.00e+00	994.00
IUUC-Tme-127170	Tuber melanosporum	48.91	0.00e+00	1195.00
IUUC-Tbe-127882	Tupaia belangeri	70.32	2.00e-130	460.00
IUUC-Ttr-128217	Tursiops truncatus	54.49	0.00e+00	1332.00
IUUC-Uma-129337	Ustilago maydis	55.49	0.00e+00	1009.00
IUUC-Vda-129828	Verticillium dahliae	48.26	0.00e+00	1137.00
IUUC-Vpa-130537	Vicugna pacos	56.04	0.00e+00	1376.00
IUUC-Vvi-130958	Vitis vinifera	87.19	0.00e+00	2178.00
IUUC-Xtr-132857	Xenopus tropicalis	54.52	0.00e+00	1313.00
IUUC-Xma-133138	Xiphophorus maculatus	55.74	0.00e+00	1374.00
IUUC-Yli-134399	Yarrowia lipolytica	49.94	0.00e+00	859.00
IUUC-Zma-135612	Zea mays	78.59	0.00e+00	2028.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence