iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026933

Ensembl Protein ID

AAW44775

UniProt Accession

Q5KDJ3; Q5KDJ3_CRYNJ

Genbank Protein ID

AAW44775.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AE017347

Gene Name

CNG03780

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNG03780	AAW44775	AAW44775

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	7.50e-135	447.4	362	674
E3 adaptor/Cullin RING/DCX/DWD	7.00e-22	75.1	505	534

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.......eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtltg 94
           p+kvldap+l+ddfylnL++Ws++nvl v+L+s+vylwsa++++v+kl+dl       e +d +  ++w+++g+ la+Gt++g vei+D+e +k++r+++g
   Q: 362  PFKVLDAPDLADDFYLNLISWSASNVLGVGLNSCVYLWSAQSSKVTKLCDLaagvelgEGGDVIRGLEWTNKGSTLAIGTNNGLVEIWDAEYCKRIRVMSG 462
           689***********************************************99998888889**************************************** PP
   S: 95   hsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqa.haqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfkehkaavkaiawsPwqksl 194
           hs rvgaL+Wn+++lssGsrd++ilhrd r++++ +++lq+ h+qe+CGl+wn d+ +LasGGnDn++ vw   + +P+ +f eh+aavkaiawsP+q++l
   Q: 463  HSGRVGALAWNSHILSSGSRDRTILHRDTRIPDQYIRRLQGhHKQEICGLRWNCDTDQLASGGNDNKLFVWGGVDARPTWRFGEHRAAVKAIAWSPHQRGL 563
           ************************************999972589******************************************************** PP
   S: 195  LasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfa....enkitlwkypslskvaelkgheaRvlslalspdgeaivtaagDetl 291
           LasGGGtaD++i+fwn+ltg l++eidtgsqvc+l+wsk+s+e+vsthG++    +n+i +wkyps++++a+l+gh++Rvl+la+spdg++ivt+agDetl
   Q: 564  LASGGGTADKKIRFWNSLTGGLVSEIDTGSQVCNLMWSKNSNEIVSTHGYSggpiSNQIHIWKYPSMTQIATLTGHNYRVLYLAMSPDGQTIVTGAGDETL 664
           **************************************************85555699******************************************* PP
   S: 292  rfwklfdkkk 301
           rfw+ f+k k
   Q: 665  RFWNAFQKAK 674
           ******9976 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+ ++++l++  d + l+sG++D+++ vW 
   Q: 505  HKQEICGLRWnCDtDQLASGGNDNKLFVWG 534
           999*******966699*************7 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MSIYDTEFSR RIRSSITVPP SPVSQSPRYD LRSTNPAVAS SSRLGPAGVE ARESKMDVFG 60
SVGMTPTKSS SPRLKGKGIT REYGDRFIPT REGSDLHAAY QFMEGVRGQV KVKTRRKSGQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCGAACAG CACAAGATAT GTCCATCTAC GATACAGAGT TCTCTCGCCG TATCCGCTCC 60
TCAATTACAG TACCGCCGTC ACCTGTTTCT CAATCACCAA GATATGACCT TCGATCAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR013979--TIF_beta_prop-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF08662--eIF2A
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

cne:CNG03780

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	58.51	7.00e-109	385.00
IUUC-Aml-002003	Ailuropoda melanoleuca	59.58	1.00e-127	447.00
IUUC-Atr-002753	Amborella trichopoda	54.81	1.00e-117	414.00
IUUC-Apl-003212	Anas platyrhynchos	51.24	8.00e-130	455.00
IUUC-Aca-004920	Anolis carolinensis	45.26	1.00e-81	294.00
IUUC-Aly-005442	Arabidopsis lyrata	55.97	6.00e-125	439.00
IUUC-Ath-006938	Arabidopsis thaliana	55.45	2.00e-124	436.00
IUUC-Ago-007784	Ashbya gossypii	46.80	1.00e-105	375.00
IUUC-Acl-008269	Aspergillus clavatus	56.29	1.00e-137	481.00
IUUC-Afl-008432	Aspergillus flavus	57.69	3.00e-138	483.00
IUUC-Afu-008829	Aspergillus fumigatus	58.10	2.00e-137	481.00
IUUC-Ani-009471	Aspergillus nidulans	57.49	4.00e-137	479.00
IUUC-Ang-009711	Aspergillus niger	56.29	7.00e-137	479.00
IUUC-Aor-010118	Aspergillus oryzae	57.69	3.00e-138	483.00
IUUC-Ate-010534	Aspergillus terreus	56.77	4.00e-138	483.00
IUUC-Ame-010685	Astyanax mexicanus	62.73	2.00e-122	430.00
IUUC-Bgr-012013	Blumeria graminis	56.53	5.00e-138	483.00
IUUC-Bta-012586	Bos taurus	51.03	4.00e-129	452.00
IUUC-Bci-013807	Botrytis cinerea	62.93	5.00e-129	452.00
IUUC-Bdi-014981	Brachypodium distachyon	64.51	7.00e-123	432.00
IUUC-Bol-016301	Brassica oleracea	55.47	2.00e-124	437.00
IUUC-Bra-017453	Brassica rapa	55.47	2.00e-124	437.00
IUUC-Cel-018472	Caenorhabditis elegans	56.89	1.00e-116	412.00
IUUC-Cja-019929	Callithrix jacchus	51.24	3.00e-129	453.00
IUUC-Cfa-020977	Canis familiaris	51.24	2.00e-129	453.00
IUUC-Cpo-021537	Cavia porcellus	51.65	4.00e-130	456.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	48.01	2.00e-85	307.00
IUUC-Csa-023389	Chlorocebus sabaeus	51.24	2.00e-129	453.00
IUUC-Cho-024920	Choloepus hoffmanni	49.14	4.00e-33	134.00
IUUC-Cin-025327	Ciona intestinalis	56.79	7.00e-117	412.00
IUUC-Csv-025921	Ciona savignyi	59.60	1.00e-120	424.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	57.63	1.00e-138	484.00
IUUC-Cme-027143	Cyanidioschyzon merolae	58.15	6.00e-109	386.00
IUUC-Dre-027470	Danio rerio	58.79	2.00e-121	427.00
IUUC-Dno-029629	Dasypus novemcinctus	61.99	3.00e-114	403.00
IUUC-Dor-030187	Dipodomys ordii	58.27	2.00e-124	437.00
IUUC-Dse-031502	Dothistroma septosporum	55.42	6.00e-126	442.00
IUUC-Dme-031858	Drosophila melanogaster	62.10	1.00e-126	444.00
IUUC-Ete-032562	Echinops telfairi	69.57	6.00e-82	296.00
IUUC-Eca-034210	Equus caballus	51.03	6.00e-129	452.00
IUUC-Eeu-035059	Erinaceus europaeus	47.98	5.00e-66	243.00
IUUC-Fca-035839	Felis catus	59.58	3.00e-128	449.00
IUUC-Fal-036895	Ficedula albicollis	51.24	9.00e-130	454.00
IUUC-Fox-037814	Fusarium oxysporum	65.05	3.00e-131	459.00
IUUC-Fso-038420	Fusarium solani	60.00	5.00e-137	479.00
IUUC-Gmo-039544	Gadus morhua	63.75	6.00e-123	432.00
IUUC-Ggr-039774	Gaeumannomyces graminis	59.10	3.00e-137	479.00
IUUC-Gga-041025	Gallus gallus	51.24	9.00e-130	454.00
IUUC-Gac-041596	Gasterosteus aculeatus	59.42	2.00e-123	433.00
IUUC-Gma-043563	Glycine max	62.42	5.00e-116	409.00
IUUC-Ggo-045599	Gorilla gorilla	51.24	4.00e-123	432.00
IUUC-Hsa-046695	Homo sapiens	51.24	2.00e-129	453.00
IUUC-Hvu-047486	Hordeum vulgare	61.38	1.00e-103	367.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	51.45	9.00e-130	454.00
IUUC-Kpa-049239	Komagataella pastoris	59.42	5.00e-126	442.00
IUUC-Lch-049827	Latimeria chalumnae	59.32	2.00e-122	430.00
IUUC-Lpe-051568	Leersia perrieri	58.36	6.00e-108	382.00
IUUC-Loc-052856	Lepisosteus oculatus	64.02	1.00e-122	431.00
IUUC-Laf-053742	Loxodonta africana	46.32	4.00e-85	306.00
IUUC-Mcc-055601	Macaca mulatta	51.24	2.00e-129	453.00
IUUC-Meu-056276	Macropus eugenii	59.94	1.00e-115	407.00
IUUC-Mor-057113	Magnaporthe oryzae	64.84	5.00e-137	479.00
IUUC-Mpo-057599	Magnaporthe poae	59.10	2.00e-137	480.00
IUUC-Mtr-057760	Medicago truncatula	63.29	2.00e-119	420.00
IUUC-Mla-059048	Melampsora laricipopulina	58.87	3.00e-124	436.00
IUUC-Mga-060097	Meleagris gallopavo	47.44	2.00e-114	404.00
IUUC-Mvi-060465	Microbotryum violaceum	62.03	1.00e-139	487.00
IUUC-Mmr-061151	Microcebus murinus	46.17	6.00e-104	369.00
IUUC-Mdo-063062	Monodelphis domestica	51.24	9.00e-130	454.00
IUUC-Mmu-063731	Mus musculus	51.03	3.00e-128	450.00
IUUC-Mac-064942	Musa acuminata	59.53	3.00e-119	419.00
IUUC-Mpu-066173	Mustela putorius furo	51.45	8.00e-130	454.00
IUUC-Mlu-068030	Myotis lucifugus	50.83	1.00e-128	451.00
IUUC-Nfi-068536	Neosartorya fischeri	55.82	4.00e-137	479.00
IUUC-Ncr-068734	Neurospora crassa	64.93	2.00e-138	484.00
IUUC-Nle-070163	Nomascus leucogenys	51.24	3.00e-129	453.00
IUUC-Opr-070974	Ochotona princeps	60.73	4.00e-98	348.00
IUUC-Ont-072272	Oreochromis niloticus	59.95	1.00e-123	434.00
IUUC-Oan-073634	Ornithorhynchus anatinus	62.30	1.00e-108	383.00
IUUC-Ocu-073797	Oryctolagus cuniculus	46.32	3.00e-85	307.00
IUUC-Oba-075417	Oryza barthii	60.19	6.00e-108	382.00
IUUC-Obr-076123	Oryza brachyantha	61.58	2.00e-119	421.00
IUUC-Ogl-077294	Oryza glaberrima	61.88	9.00e-119	418.00
IUUC-Ogu-077996	Oryza glumaepatula	61.88	8.00e-119	418.00
IUUC-Oin-080172	Oryza indica	61.88	2.00e-118	417.00
IUUC-Olo-081068	Oryza longistaminata	61.88	1.00e-118	417.00
IUUC-Ome-081250	Oryza meridionalis	61.88	1.00e-118	418.00
IUUC-Oni-083048	Oryza nivara	61.88	9.00e-119	418.00
IUUC-Opu-083333	Oryza punctata	61.88	7.00e-119	418.00
IUUC-Oru-085001	Oryza rufipogon	61.88	1.00e-118	418.00
IUUC-Osa-086243	Oryza sativa	61.88	9.00e-119	418.00
IUUC-Ola-087094	Oryzias latipes	59.69	4.00e-123	432.00
IUUC-Olu-087647	Ostreococcus lucimarinus	47.26	5.00e-92	329.00
IUUC-Oga-088911	Otolemur garnettii	51.03	6.00e-129	452.00
IUUC-Oar-089508	Ovis aries	51.03	4.00e-129	452.00
IUUC-Ptr-090935	Pan troglodytes	40.35	3.00e-85	307.00
IUUC-Pan-092147	Papio anubis	51.24	2.00e-129	453.00
IUUC-Psi-093702	Pelodiscus sinensis	51.03	1.00e-128	451.00
IUUC-Pma-094581	Petromyzon marinus	58.12	2.00e-124	437.00
IUUC-Pno-095139	Phaeosphaeria nodorum	60.42	2.00e-120	424.00
IUUC-Ppa-095518	Physcomitrella patens	61.92	9.00e-126	441.00
IUUC-Pfo-096309	Poecilia formosa	59.95	1.00e-123	434.00
IUUC-Pab-098603	Pongo abelii	39.14	5.00e-85	306.00
IUUC-Pop-098924	Populus trichocarpa	55.28	3.00e-117	413.00
IUUC-Pca-100565	Procavia capensis	63.75	3.00e-123	433.00
IUUC-Ppe-101924	Prunus persica	53.83	1.00e-119	421.00
IUUC-Pva-102602	Pteropus vampyrus	51.27	9.00e-125	438.00
IUUC-Pgr-103466	Puccinia graminis	60.68	3.00e-128	450.00
IUUC-Ptt-103888	Puccinia triticina	59.31	1.00e-116	411.00
IUUC-Pte-104097	Pyrenophora teres	60.48	1.00e-135	474.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	55.91	4.00e-119	419.00
IUUC-Rno-105028	Rattus norvegicus	51.24	6.00e-129	452.00
IUUC-Sce-106240	Saccharomyces cerevisiae	44.88	1.00e-102	365.00
IUUC-Sha-106538	Sarcophilus harrisii	54.60	6.00e-115	405.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	58.11	2.00e-117	413.00
IUUC-Spo-108369	Schizosaccharomyces pombe	51.33	2.00e-112	397.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	57.54	2.00e-130	457.00
IUUC-Smo-109041	Selaginella moellendorffii	62.72	5.00e-126	442.00
IUUC-Sit-110550	Setaria italica	63.30	1.00e-121	427.00
IUUC-Sly-111446	Solanum lycopersicum	59.94	5.00e-119	419.00
IUUC-Stu-112491	Solanum tuberosum	59.67	2.00e-118	417.00
IUUC-Sar-113092	Sorex araneus	44.41	7.00e-77	279.00
IUUC-Sbi-114386	Sorghum bicolor	62.69	3.00e-120	423.00
IUUC-Sre-115222	Sporisorium reilianum	62.34	4.00e-145	506.00
IUUC-Ssc-116171	Sus scrofa	51.03	4.00e-129	452.00
IUUC-Tgu-116878	Taeniopygia guttata	43.94	6.00e-101	358.00
IUUC-Tru-118222	Takifugu rubripes	59.42	8.00e-124	435.00
IUUC-Tni-119863	Tetraodon nigroviridis	59.95	2.00e-124	437.00
IUUC-Tca-121599	Theobroma cacao	55.58	8.00e-118	415.00
IUUC-Tre-122249	Trichoderma reesei	58.33	2.00e-137	480.00
IUUC-Tvi-122675	Trichoderma virens	58.33	7.00e-138	482.00
IUUC-Tae-123489	Triticum aestivum	61.58	9.00e-124	435.00
IUUC-Tur-126545	Triticum urartu	54.60	8.00e-100	355.00
IUUC-Tme-127151	Tuber melanosporum	60.10	7.00e-146	508.00
IUUC-Tbe-128056	Tupaia belangeri	57.51	9.00e-98	347.00
IUUC-Ttr-129055	Tursiops truncatus	51.87	4.00e-128	449.00
IUUC-Uma-129555	Ustilago maydis	60.85	6.00e-142	495.00
IUUC-Vda-130027	Verticillium dahliae	64.91	2.00e-137	481.00
IUUC-Vvi-131749	Vitis vinifera	55.91	5.00e-121	426.00
IUUC-Xtr-132808	Xenopus tropicalis	51.14	3.00e-129	453.00
IUUC-Xma-133183	Xiphophorus maculatus	59.95	1.00e-123	434.00
IUUC-Yli-134584	Yarrowia lipolytica	64.79	4.00e-140	489.00
IUUC-Zma-135640	Zea mays	62.69	1.00e-120	424.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence