iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071555

Ensembl Protein ID

ENSONIP00000021963.1

UniProt Accession

I3KLG8; I3KLG8_ORENI

Genbank Protein ID

ENSONIP00000021963

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Genbank Nucleotide ID

AERX01040309

Gene Name

wdr4; WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000017415.1	ENSONIT00000021982.1	ENSONIP00000021963.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.40e-08	33.9	187	227

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH   v++l+   +  + l+sGs+Dgt+k+WD+ +g  l+s
   Q: 187  GHRQFVSALQIlsTHpHWLLSGSGDGTLKLWDYESGSELQS 227
           688889999988533577****************9998886 PP

Organism

Oreochromis niloticus

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MSAVGFCGNW IIVTCDKKLF AVHTKEAREP FVFDCSTAEK KPKNTQDEKN SDGGSSEETG 60
SDKVLAFAVS PSGKLLALSD DTKRLVLFSC EPSWHCISIR WVVRRCTSLV FTQAEDELLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTGCTG TAGGTTTTTG TGGAAACTGG ATTATTGTCA CCTGCGACAA AAAACTCTTT 60
GCAGTCCATA CAAAGGAAGC CAGGTTTGAA TGACTTTAAA TCTCTTTCTT TGGTTCCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0036265--P:RNA (guanine-N7)-methylation
GO:0030488--P:tRNA methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	28.47	2.00e-07	50.40
IUUC-Atr-002431	Amborella trichopoda	36.44	7.00e-13	66.20
IUUC-Apl-003975	Anas platyrhynchos	47.31	4.00e-88	318.00
IUUC-Aca-005170	Anolis carolinensis	43.14	2.00e-70	259.00
IUUC-Aly-005769	Arabidopsis lyrata	30.10	6.00e-26	112.00
IUUC-Ath-006733	Arabidopsis thaliana	31.62	2.00e-24	107.00
IUUC-Acl-008151	Aspergillus clavatus	40.87	4.00e-15	76.30
IUUC-Afl-008518	Aspergillus flavus	41.67	7.00e-15	74.70
IUUC-Afu-009102	Aspergillus fumigatus	27.80	8.00e-16	78.60
IUUC-Ani-009442	Aspergillus nidulans	26.19	9.00e-14	71.60
IUUC-Aor-010133	Aspergillus oryzae	41.67	8.00e-15	75.10
IUUC-Ate-010465	Aspergillus terreus	41.18	3.00e-13	70.10
IUUC-Ame-010613	Astyanax mexicanus	54.94	2.00e-117	416.00
IUUC-Bgr-012067	Blumeria graminis	30.48	4.00e-21	96.30
IUUC-Bta-012788	Bos taurus	43.31	2.00e-81	296.00
IUUC-Bdi-014458	Brachypodium distachyon	31.08	4.00e-14	72.80
IUUC-Bol-016398	Brassica oleracea	33.20	4.00e-25	109.00
IUUC-Bra-017059	Brassica rapa	32.52	6.00e-25	108.00
IUUC-Cpo-021963	Cavia porcellus	41.33	2.00e-76	279.00
IUUC-Csa-024148	Chlorocebus sabaeus	41.25	3.00e-68	252.00
IUUC-Cne-026834	Cryptococcus neoformans	35.57	6.00e-19	89.40
IUUC-Dre-028427	Danio rerio	53.72	5.00e-127	447.00
IUUC-Dno-028881	Dasypus novemcinctus	37.97	2.00e-68	253.00
IUUC-Dor-030522	Dipodomys ordii	42.17	6.00e-82	297.00
IUUC-Dme-032136	Drosophila melanogaster	38.34	1.00e-24	107.00
IUUC-Fca-035833	Felis catus	46.33	3.00e-78	285.00
IUUC-Fal-037497	Ficedula albicollis	45.24	4.00e-87	314.00
IUUC-Gga-040547	Gallus gallus	45.33	2.00e-85	309.00
IUUC-Gac-041761	Gasterosteus aculeatus	66.58	1.00e-147	516.00
IUUC-Gma-043722	Glycine max	28.87	3.00e-20	92.80
IUUC-Ggo-045340	Gorilla gorilla	41.51	3.00e-71	262.00
IUUC-Hsa-046403	Homo sapiens	42.30	1.00e-72	266.00
IUUC-Hvu-047643	Hordeum vulgare	30.07	1.00e-15	77.40
IUUC-Itr-048103	Ictidomys tridecemlineatus	42.97	7.00e-85	307.00
IUUC-Kpa-049283	Komagataella pastoris	32.75	2.00e-17	83.60
IUUC-Lch-050682	Latimeria chalumnae	45.57	1.00e-93	337.00
IUUC-Lpe-050712	Leersia perrieri	29.02	9.00e-26	111.00
IUUC-Loc-052599	Lepisosteus oculatus	51.48	1.00e-118	419.00
IUUC-Laf-054390	Loxodonta africana	44.36	1.00e-85	310.00
IUUC-Mcc-054747	Macaca mulatta	42.30	2.00e-71	263.00
IUUC-Mtr-058600	Medicago truncatula	35.02	3.00e-24	106.00
IUUC-Mla-059129	Melampsora laricipopulina	25.93	1.00e-12	67.00
IUUC-Mga-059876	Meleagris gallopavo	46.74	3.00e-87	315.00
IUUC-Mvi-060359	Microbotryum violaceum	31.14	1.00e-13	71.60
IUUC-Mmr-061518	Microcebus murinus	42.45	9.00e-77	280.00
IUUC-Mac-065417	Musa acuminata	29.68	1.00e-23	104.00
IUUC-Nfi-068402	Neosartorya fischeri	28.16	1.00e-16	81.60
IUUC-Nle-069914	Nomascus leucogenys	40.73	6.00e-65	241.00
IUUC-Oan-072951	Ornithorhynchus anatinus	43.64	4.00e-82	298.00
IUUC-Ocu-074679	Oryctolagus cuniculus	41.25	3.00e-70	258.00
IUUC-Oba-075355	Oryza barthii	27.03	3.00e-12	66.60
IUUC-Obr-076769	Oryza brachyantha	28.34	3.00e-26	113.00
IUUC-Ogl-077168	Oryza glaberrima	28.68	9.00e-27	114.00
IUUC-Ogu-078275	Oryza glumaepatula	27.03	5.00e-12	65.90
IUUC-Oin-079207	Oryza indica	28.68	9.00e-27	114.00
IUUC-Oni-082437	Oryza nivara	26.60	3.00e-12	66.60
IUUC-Opu-084031	Oryza punctata	29.47	2.00e-25	110.00
IUUC-Oru-084380	Oryza rufipogon	27.03	5.00e-12	65.90
IUUC-Osa-085327	Oryza sativa	28.68	1.00e-26	114.00
IUUC-Ola-086716	Oryzias latipes	58.18	4.00e-128	451.00
IUUC-Olu-087708	Ostreococcus lucimarinus	27.69	9.00e-17	81.30
IUUC-Oar-090239	Ovis aries	43.49	8.00e-82	297.00
IUUC-Ptr-090851	Pan troglodytes	41.78	8.00e-72	264.00
IUUC-Pan-092558	Papio anubis	41.04	8.00e-67	247.00
IUUC-Psi-093792	Pelodiscus sinensis	42.11	8.00e-85	307.00
IUUC-Ppa-095757	Physcomitrella patens	29.21	1.00e-21	97.40
IUUC-Pfo-096465	Poecilia formosa	63.64	9.00e-146	509.00
IUUC-Pab-097722	Pongo abelii	44.51	6.00e-74	271.00
IUUC-Pop-098979	Populus trichocarpa	34.54	8.00e-21	95.10
IUUC-Pca-100753	Procavia capensis	41.80	5.00e-52	198.00
IUUC-Ppe-101515	Prunus persica	33.49	4.00e-22	99.40
IUUC-Sja-107780	Schizosaccharomyces japonicus	27.31	5.00e-14	72.40
IUUC-Spo-108251	Schizosaccharomyces pombe	27.54	2.00e-16	80.10
IUUC-Smo-108938	Selaginella moellendorffii	33.21	4.00e-26	112.00
IUUC-Sit-110020	Setaria italica	30.98	1.00e-22	100.00
IUUC-Sly-111543	Solanum lycopersicum	34.98	1.00e-22	101.00
IUUC-Stu-111925	Solanum tuberosum	32.48	5.00e-23	102.00
IUUC-Sbi-114061	Sorghum bicolor	33.19	9.00e-21	94.70
IUUC-Tgu-117321	Taeniopygia guttata	45.14	1.00e-80	293.00
IUUC-Tru-118454	Takifugu rubripes	62.40	2.00e-135	475.00
IUUC-Tni-119894	Tetraodon nigroviridis	59.79	3.00e-121	428.00
IUUC-Tca-121746	Theobroma cacao	33.18	2.00e-23	103.00
IUUC-Tae-124459	Triticum aestivum	29.67	4.00e-16	79.30
IUUC-Tur-126254	Triticum urartu	28.42	3.00e-09	56.60
IUUC-Tbe-127683	Tupaia belangeri	53.85	9.00e-24	104.00
IUUC-Ttr-129056	Tursiops truncatus	41.41	3.00e-74	272.00
IUUC-Vvi-131428	Vitis vinifera	36.22	3.00e-23	103.00
IUUC-Xma-133605	Xiphophorus maculatus	63.03	3.00e-147	514.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence