iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
POPTR_0009s07960	POPTR_0009s07960.2	POPTR_0009s07960.2
POPTR_0009s07960	POPTR_0009s07960.1	POPTR_0009s07960.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.50e-170	569.0	479	966

Active Site

Position(s)	Description	Evidence
660	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnp 86
           YD Qi ++G++ q+kl+ a+ ++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLfr++++g+ K+ vaa a++ +np
   Q: 479  YDAQISVFGSKLQKKLEDANLFVVGSGALGCEFLKNLALMGVscgeqGKLTITDDDVIEKSNLSRQFLFRDWNIGQAKSTVAASAAALINP 569
           ******************************************************************************************* PP
   S: 87   dvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfc 174
           + ++ea ++++  ++e+++   F ++++ Vv+aldn+ ar++v+++cl+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+c
   Q: 570  HLKIEALQNRVGSETENVFddtFWENLTAVVNALDNVNARLYVDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMC 660
           *****************99************************************************************************ PP
   S: 175  tlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsi 253
           t+ ++p +++h+++wa            + +n +l++  + ++  +k   ++++++++ v + l++e+ e+f+++i++a+  f+ ++   +
   Q: 661  TVHSFPHNIDHCLTWArsefeglvektpAEVNAYLSNPVEYTNAMNKAGDAQSRDTLEHVLECLEKEKCETFQDCITWARLRFEDYFADRV 751
           **************************999999999999999999999999***************************************** PP
   S: 254  kqllksfecdivtkskspfwv.........................................................sfcsnaealqvpe 287
           kql+  f+ d  t+ ++pfw+                                                         +f + ++a+ + +
   Q: 752  KQLIFTFPEDASTSTGAPFWSapkrfphplqfsvvdpshlhfvmaasilraetfgisvpewakhpkmlaeavekvvvpEFQPREDAKIETD 842
           **************************************************************99999888888888887777776655443 PP
   S: 288  kvekdeevvkasap..lylllralerfekkk..grkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiatt 372
             +      +++++  +  l+++le+ ++k   g  ++ ++fekddd   ++dl++ +an+ra +++i++ +d+ + k iag+iipaiat 
   Q: 843  EKATTLSSASVDDAavINELIKKLEQCRQKLplGFRMTPIQFEKDDDTnyHMDLIAGLANMRARNYSIPE-VDKLKAKFIAGRIIPAIATS 932
           3333333333333358**********999853378999********************************.******************** PP
   S: 373  navvgGlaaqEviKvvsg..kfeplknfflfdae 404
           +a+  Gl+++E++Kv++g  k e ++n+f ++a+
   Q: 933  TAMATGLVCLELYKVLDGghKVEDYRNTFANLAL 966
           ******************999********99875 PP

Organism

Populus trichocarpa

Protein Sequence
(Fasta)

MLPKKRPVEA EEAPDNSISD SSSFKKKRVD CDLESTVICN KKSCVTGNCS NTETETNNHC 60
KEEHLIMAPG DSNPMEIDED LHSRQLAVYG RETMRRLFGS NVLVSGMQGL GAEIAKNLIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAAACCTC TCCATTTTTC TCCACAAGCT ACCAAAAACC AAACCCCAAT CTTTTCTCCC 60
TCCCTCCCCT CACACTCCAT CATCCTTCCC TTGCTCACAG TGCTAAGCGG TACGTTTACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

pop:POPTR_0009s07960g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ath-006992	Arabidopsis thaliana	79.22	0.00e+00	1739.00
IUUC-Acl-008181	Aspergillus clavatus	45.06	0.00e+00	825.00
IUUC-Afu-009065	Aspergillus fumigatus	45.65	0.00e+00	855.00
IUUC-Ani-009371	Aspergillus nidulans	46.04	0.00e+00	828.00
IUUC-Ate-010466	Aspergillus terreus	45.38	0.00e+00	856.00
IUUC-Ggr-039823	Gaeumannomyces graminis	45.37	0.00e+00	876.00
IUUC-Lma-053315	Leptosphaeria maculans	44.26	0.00e+00	884.00
IUUC-Nfi-068407	Neosartorya fischeri	45.55	0.00e+00	835.00
IUUC-Ppa-095227	Physcomitrella patens	68.91	0.00e+00	1509.00
IUUC-Tbe-127714	Tupaia belangeri	33.83	2.00e-137	483.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence