iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006897

UUCD1 version

UUC-ArT-01635

Ensembl Protein ID

AT3G20060.1

UniProt Accession

Q9LJZ5; A8MSD2; UBC19_ARATH

Genbank Protein ID

AAM96886.1; AAY44859.1; BAB01863.1; AEE76325.1; AEE76326.1; ABF58954.1

Protein Name

Ubiquitin-conjugating enzyme E2 19; E2 ubiquitin-conjugating enzyme 19; Ubiquitin carrier protein 19

Genbank Nucleotide ID

AY127573; DQ027033; AP000383; CP002686; CP002686; BT025536

Gene Name

UBC19; At3g20060; MAL21.6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G20060	AT3G20060.1	AT3G20060.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.30e-45	154.6	40	173

Active Site

Position(s)	Description	Evidence
120	Glycyl thioester intermediate	N/A

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsv 98
           Rl+ el+ l+    +gisa p+++ +++ w+ +i+G +dt++eg  ++l+++f++dYPfk+Pkvkf+t +fhPnv+  G++Cl+il+  +kWs+a++v
   Q: 40   RLQSELMGLMMGADPGISAFPEED-NIFCWKGTITGSKDTVFEGTEYRLSLTFSNDYPFKSPKVKFETCCFHPNVDLYGNICLDILQ--DKWSSAYDV 134
           99**********************.9************************************************************9..********* PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +++llsiqsll epn++spln++aa+l+++++e y+k+v+
   Q: 135  RTILLSIQSLLGEPNISSPLNNQAAQLWSNQEE-YRKMVE 173
           ****************************88776.***996 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Part of the anaphase-promoting complex (APC). May have a key function during cell cycle and be involved in cyclin B1 degradation.

Protein Sequence
(Fasta)

MATVNGYTGN TPAATTPAAT GSKQSAPPTK TVDSHSVLKR LQSELMGLMM GADPGISAFP 60
EEDNIFCWKG TITGSKDTVF EGTEYRLSLT FSNDYPFKSP KVKFETCCFH PNVDLYGNIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGACGACGTT TCTTGTGTCG TACACGTTTT ATAACCCAGA CCCACGTCTC TCTCTCTCAA 60
AGAAGAGAAG AAGAACTCTC TCTCTATCTC TATCTCTATC TCTCTTCTCC TTCTTCTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0008283--P:cell proliferation
GO:0000209--P:protein polyubiquitination
GO:0030071--P:regulation of mitotic metaphase/anaphase transition
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ath:AT3G20060

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001924	Ailuropoda melanoleuca	60.93	5.00e-50	189.00
IUUC-Atr-002885	Amborella trichopoda	80.89	2.00e-72	263.00
IUUC-Aly-006086	Arabidopsis lyrata	97.79	2.00e-98	350.00
IUUC-Acl-008223	Aspergillus clavatus	56.34	4.00e-39	153.00
IUUC-Afl-008675	Aspergillus flavus	56.49	4.00e-41	159.00
IUUC-Afu-008997	Aspergillus fumigatus	56.16	3.00e-39	153.00
IUUC-Ani-009470	Aspergillus nidulans	58.22	5.00e-41	159.00
IUUC-Ang-009648	Aspergillus niger	55.63	5.00e-41	159.00
IUUC-Aor-009977	Aspergillus oryzae	57.50	4.00e-32	129.00
IUUC-Ate-010318	Aspergillus terreus	57.24	7.00e-41	159.00
IUUC-Ame-011302	Astyanax mexicanus	63.01	2.00e-52	197.00
IUUC-Bta-013101	Bos taurus	59.74	7.00e-52	195.00
IUUC-Bci-013787	Botrytis cinerea	51.61	1.00e-44	171.00
IUUC-Bdi-014144	Brachypodium distachyon	79.17	2.00e-67	246.00
IUUC-Bol-015436	Brassica oleracea	93.37	5.00e-95	338.00
IUUC-Bra-017249	Brassica rapa	94.48	4.00e-96	342.00
IUUC-Cfa-020588	Canis familiaris	61.07	3.00e-51	193.00
IUUC-Cpo-021384	Cavia porcellus	59.74	7.00e-52	195.00
IUUC-Csa-023437	Chlorocebus sabaeus	58.97	2.00e-52	197.00
IUUC-Cho-024330	Choloepus hoffmanni	67.83	7.00e-44	167.00
IUUC-Csv-025933	Ciona savignyi	60.69	4.00e-50	189.00
IUUC-Cgl-026494	Colletotrichum gloeosporioides	53.10	6.00e-42	162.00
IUUC-Dre-027375	Danio rerio	61.22	6.00e-52	195.00
IUUC-Dno-029921	Dasypus novemcinctus	59.73	1.00e-49	187.00
IUUC-Dor-030209	Dipodomys ordii	57.14	7.00e-48	182.00
IUUC-Dse-031516	Dothistroma septosporum	46.31	1.00e-34	138.00
IUUC-Dme-031942	Drosophila melanogaster	61.54	1.00e-54	204.00
IUUC-Eca-034073	Equus caballus	61.07	3.00e-51	193.00
IUUC-Fca-035666	Felis catus	61.07	3.00e-51	193.00
IUUC-Fox-037793	Fusarium oxysporum	53.79	2.00e-43	167.00
IUUC-Fso-038151	Fusarium solani	54.23	2.00e-43	167.00
IUUC-Gmo-038894	Gadus morhua	66.92	7.00e-47	178.00
IUUC-Ggr-039730	Gaeumannomyces graminis	54.23	3.00e-37	147.00
IUUC-Gga-040537	Gallus gallus	61.72	2.00e-46	176.00
IUUC-Gac-041346	Gasterosteus aculeatus	61.31	1.00e-46	178.00
IUUC-Gma-043989	Glycine max	80.56	3.00e-81	293.00
IUUC-Ggo-045594	Gorilla gorilla	57.59	2.00e-50	191.00
IUUC-Hsa-046216	Homo sapiens	58.33	7.00e-52	195.00
IUUC-Hvu-047797	Hordeum vulgare	74.29	1.00e-60	224.00
IUUC-Itr-048402	Ictidomys tridecemlineatus	61.07	3.00e-51	193.00
IUUC-Kpa-049294	Komagataella pastoris	57.33	5.00e-47	179.00
IUUC-Lch-049761	Latimeria chalumnae	54.97	3.00e-46	177.00
IUUC-Lpe-051089	Leersia perrieri	71.07	2.00e-66	244.00
IUUC-Loc-052297	Lepisosteus oculatus	64.79	9.00e-53	199.00
IUUC-Lma-053214	Leptosphaeria maculans	51.75	4.00e-42	162.00
IUUC-Laf-054468	Loxodonta africana	58.23	5.00e-51	192.00
IUUC-Mcc-055338	Macaca mulatta	58.97	2.00e-52	197.00
IUUC-Meu-056147	Macropus eugenii	60.39	7.00e-53	198.00
IUUC-Mor-057239	Magnaporthe oryzae	50.33	3.00e-42	163.00
IUUC-Mpo-057491	Magnaporthe poae	54.23	4.00e-43	166.00
IUUC-Mla-058880	Melampsora laricipopulina	58.04	3.00e-47	180.00
IUUC-Mvi-060528	Microbotryum violaceum	56.46	1.00e-44	172.00
IUUC-Mmr-060747	Microcebus murinus	64.96	2.00e-49	187.00
IUUC-Mdo-062343	Monodelphis domestica	60.39	5.00e-52	196.00
IUUC-Mmu-063563	Mus musculus	59.09	2.00e-50	191.00
IUUC-Mac-064777	Musa acuminata	80.00	7.00e-69	252.00
IUUC-Mpu-066541	Mustela putorius furo	63.57	3.00e-50	190.00
IUUC-Mlu-067388	Myotis lucifugus	59.60	1.00e-48	184.00
IUUC-Nfi-068577	Neosartorya fischeri	53.74	9.00e-38	148.00
IUUC-Ncr-068803	Neurospora crassa	52.03	4.00e-35	139.00
IUUC-Opr-070902	Ochotona princeps	63.57	2.00e-50	191.00
IUUC-Ont-071672	Oreochromis niloticus	64.23	5.00e-50	189.00
IUUC-Ocu-074566	Oryctolagus cuniculus	64.23	2.00e-50	190.00
IUUC-Oba-075538	Oryza barthii	78.20	2.00e-61	226.00
IUUC-Ogu-078467	Oryza glumaepatula	76.19	5.00e-67	246.00
IUUC-Oin-079533	Oryza indica	78.95	6.00e-62	228.00
IUUC-Olo-080673	Oryza longistaminata	78.20	2.00e-61	226.00
IUUC-Ome-081483	Oryza meridionalis	76.71	2.00e-66	244.00
IUUC-Oni-082321	Oryza nivara	76.19	5.00e-67	246.00
IUUC-Opu-083245	Oryza punctata	77.40	3.00e-67	246.00
IUUC-Oru-084641	Oryza rufipogon	72.26	7.00e-65	239.00
IUUC-Osa-085992	Oryza sativa	76.19	5.00e-67	246.00
IUUC-Ola-086807	Oryzias latipes	61.27	5.00e-50	189.00
IUUC-Olu-087834	Ostreococcus lucimarinus	70.80	1.00e-54	204.00
IUUC-Oga-088699	Otolemur garnettii	57.86	1.00e-50	191.00
IUUC-Oar-089542	Ovis aries	60.26	9.00e-50	188.00
IUUC-Ptr-091069	Pan troglodytes	58.33	7.00e-52	195.00
IUUC-Pan-092533	Papio anubis	58.23	6.00e-51	192.00
IUUC-Pma-094607	Petromyzon marinus	59.75	8.00e-50	188.00
IUUC-Pno-094829	Phaeosphaeria nodorum	52.45	6.00e-42	162.00
IUUC-Ppa-095861	Physcomitrella patens	70.06	6.00e-64	235.00
IUUC-Pfo-096836	Poecilia formosa	62.41	4.00e-51	192.00
IUUC-Pab-098707	Pongo abelii	58.33	7.00e-52	195.00
IUUC-Pop-099870	Populus trichocarpa	81.22	1.00e-82	297.00
IUUC-Pca-100661	Procavia capensis	60.39	1.00e-52	197.00
IUUC-Ppe-101289	Prunus persica	90.38	4.00e-82	295.00
IUUC-Pva-103235	Pteropus vampyrus	61.49	2.00e-47	181.00
IUUC-Pte-104292	Pyrenophora teres	51.43	2.00e-41	160.00
IUUC-Rno-105501	Rattus norvegicus	59.74	2.00e-51	194.00
IUUC-Sha-107205	Sarcophilus harrisii	61.36	5.00e-46	176.00
IUUC-Sja-108009	Schizosaccharomyces japonicus	55.28	9.00e-49	185.00
IUUC-Spo-108136	Schizosaccharomyces pombe	55.28	1.00e-49	188.00
IUUC-Ssl-108394	Sclerotinia sclerotiorum	54.42	2.00e-44	171.00
IUUC-Smo-109014	Selaginella moellendorffii	71.90	2.00e-62	230.00
IUUC-Sit-110754	Setaria italica	75.34	3.00e-66	243.00
IUUC-Sly-111137	Solanum lycopersicum	89.36	6.00e-74	268.00
IUUC-Stu-112305	Solanum tuberosum	85.90	2.00e-78	283.00
IUUC-Sbi-114299	Sorghum bicolor	69.80	2.00e-62	230.00
IUUC-Ssc-115625	Sus scrofa	61.07	3.00e-51	193.00
IUUC-Tni-120070	Tetraodon nigroviridis	59.85	1.00e-44	171.00
IUUC-Tre-121973	Trichoderma reesei	50.00	1.00e-43	168.00
IUUC-Tvi-122496	Trichoderma virens	55.17	6.00e-44	169.00
IUUC-Tae-123596	Triticum aestivum	76.51	1.00e-67	247.00
IUUC-Tme-127044	Tuber melanosporum	55.56	7.00e-38	149.00
IUUC-Vda-129840	Verticillium dahliae	54.48	2.00e-43	167.00
IUUC-Vvi-131685	Vitis vinifera	85.35	1.00e-78	284.00
IUUC-Xtr-132953	Xenopus tropicalis	64.34	1.00e-50	191.00
IUUC-Xma-134093	Xiphophorus maculatus	62.41	5.00e-51	192.00
IUUC-Yli-134548	Yarrowia lipolytica	55.10	1.00e-45	175.00
IUUC-Zma-135182	Zea mays	74.48	3.00e-65	240.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence