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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Spo-108317
Ensembl Protein ID SPCC962.02c.1:pep
UniProt Accession O14064; Q9USG4; Q9UTZ0; BIR1_SCHPO
Genbank Protein ID BAA83415.1; CAA20434.1; BAA87223.1
Protein Name Protein bir1; Chromosome segregation protein cut17
Genbank Nucleotide ID AB031034; CU329672; AB027919
Gene Name bir1; cut17; pbh1; SPCC962.02c; SPCP31B10.10c
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPCC962.02c SPCC962.02c.1 SPCC962.02c.1:pep
Annotation
mRNA Expression
GEO
Protein-protein Interaction
iRefIndexMentha
Post-translational Modifications (PTMs)
dbPAFdbPTM
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 29.73 6.00e-15 80.50 IUUC-Dme-031819
E3 activity/RING/RING 27.17 6.00e-15 81.30 IUUC-Hsa-046144
UBD/Alpha-Helix/UBA 27.17 6.00e-15 81.30 IUUC-Hsa-046144
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     Seems to act in the pleiotropic control of cell division. Has a role in chromosome segregation by recruiting condensin and ark1 kinase to appropriate sites as the cell progresses through mitosis. Ark1 activity depends upon bir1 function and phosphorylation. Ark1 with bir1 function is required for full-scale association with kinetochores and formation of a complex with mad3.
 Seems to act in the pleiotropic control of cell division. Has a role in chromosome segregation by recruiting condensin and ark1 kinase to appropriate sites as the cell progresses through mitosis. Ark1 activity depends upon bir1 function and phosphorylation. Ark1 with bir1 function is required for full-scale association with kinetochores and formation of a complex with mad3.
Protein Sequence
(Fasta)
MKPITSSSKR RWNRFRREMC NYSKRLDTFQ KKKWPRAKPT PETLATVGFY YNPISESNSE 60
ERLDNVTCYM CTKSFYDWED DDDPLKEHIT HSPSCPWAYI LSSKNNPNQN PQAAALTKCR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108317|E3,RING;UBD,UBA|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCCATATACG CCTTGCGAGG CGACCTTCCC TATCCTATGC ATTTGGAAGT ATCTGATATT 60
GTCTAAAGAC AATAACCAGA AGTTTTAAAA AAATTAATTT TATAGTTTTA AGGATCGGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108317|E3,RING;UBD,UBA|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0137--Centromere
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0479--Metal-binding
KW-0498--Mitosis
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
Interpro

IPR001370--BIR_rpt
PROSITE

PS50143--BIR_REPEAT_2
Pfam

PF00653--BIR
SMART

SM00238--BIR
Gene Ontology

GO:0032133--C:chromosome passenger complex
GO:0000778--C:condensed nuclear chromosome kinetochore
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:1990023--C:mitotic spindle midzone
GO:0000790--C:nuclear chromatin
GO:0031618--C:nuclear pericentric heterochromatin
GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0007076--P:mitotic chromosome condensation
GO:0000281--P:mitotic cytokinesis
GO:0000070--P:mitotic sister chromatid segregation
GO:0090307--P:mitotic spindle assembly
GO:0034501--P:protein localization to kinetochore
GO:0034503--P:protein localization to nucleolar rDNA repeats
GO:0009966--P:regulation of signal transduction
KEGG spo:SPCC962.02c
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002369 Ailuropoda melanoleuca 31.38 2.00e-17 82.40
IUUC-Apl-003549 Anas platyrhynchos 30.59 1.00e-14 72.80
IUUC-Aca-004515 Anolis carolinensis 30.72 8.00e-18 83.60
IUUC-Ath-007409 Arabidopsis thaliana 35.29 4.40e-01 26.90
IUUC-Acl-008330 Aspergillus clavatus 38.82 2.00e-38 152.00
IUUC-Afl-008648 Aspergillus flavus 37.65 2.00e-36 145.00
IUUC-Afu-008813 Aspergillus fumigatus 38.24 3.00e-36 144.00
IUUC-Ani-009424 Aspergillus nidulans 37.06 1.00e-36 146.00
IUUC-Ang-009667 Aspergillus niger 35.93 8.00e-36 143.00
IUUC-Ate-010501 Aspergillus terreus 37.72 4.00e-35 141.00
IUUC-Ame-011877 Astyanax mexicanus 31.43 3.00e-17 81.60
IUUC-Bgr-012051 Blumeria graminis 35.19 7.00e-28 117.00
IUUC-Bta-013105 Bos taurus 31.14 1.00e-18 86.30
IUUC-Bci-013905 Botrytis cinerea 37.58 2.00e-33 135.00
IUUC-Cja-018895 Callithrix jacchus 31.38 9.00e-18 83.20
IUUC-Cfa-020667 Canis familiaris 34.29 1.00e-21 96.30
IUUC-Cpo-022048 Cavia porcellus 31.47 9.00e-19 86.70
IUUC-Csa-024159 Chlorocebus sabaeus 30.00 4.00e-18 84.30
IUUC-Cho-024929 Choloepus hoffmanni 32.34 4.00e-18 84.30
IUUC-Cin-025738 Ciona intestinalis 24.76 1.00e-11 63.20
IUUC-Csv-026182 Ciona savignyi 29.41 1.00e-05 42.70
IUUC-Cgl-026472 Colletotrichum gloeosporioides 36.14 7.00e-33 134.00
IUUC-Cne-027029 Cryptococcus neoformans 28.96 1.00e-28 119.00
IUUC-Dre-028647 Danio rerio 31.18 3.00e-17 81.60
IUUC-Dno-029509 Dasypus novemcinctus 30.64 8.00e-18 83.20
IUUC-Dse-031353 Dothistroma septosporum 34.63 4.00e-37 148.00
IUUC-Dme-031819 Drosophila melanogaster 31.35 2.00e-17 82.00
IUUC-Ete-032768 Echinops telfairi 31.05 3.00e-17 81.30
IUUC-Eca-034417 Equus caballus 28.19 2.00e-18 85.50
IUUC-Eeu-035114 Erinaceus europaeus 29.95 1.00e-16 79.30
IUUC-Fca-036034 Felis catus 31.91 6.00e-18 84.00
IUUC-Fal-037656 Ficedula albicollis 30.54 1.00e-16 79.30
IUUC-Fox-037889 Fusarium oxysporum 33.16 3.00e-34 138.00
IUUC-Fso-038452 Fusarium solani 31.50 6.00e-32 130.00
IUUC-Gmo-038477 Gadus morhua 31.25 2.00e-15 75.10
IUUC-Ggr-039891 Gaeumannomyces graminis 34.15 2.00e-30 125.00
IUUC-Gga-040601 Gallus gallus 29.74 2.00e-17 82.40
IUUC-Gac-041467 Gasterosteus aculeatus 31.98 3.00e-16 77.80
IUUC-Ggo-044605 Gorilla gorilla 27.73 1.00e-17 83.20
IUUC-Hsa-046144 Homo sapiens 27.85 5.00e-18 84.00
IUUC-Itr-048379 Ictidomys tridecemlineatus 28.28 1.00e-18 85.90
IUUC-Kpa-049324 Komagataella pastoris 29.94 1.00e-20 93.60
IUUC-Lch-050259 Latimeria chalumnae 29.35 6.00e-17 80.50
IUUC-Loc-052169 Lepisosteus oculatus 32.40 4.00e-16 77.80
IUUC-Lma-052958 Leptosphaeria maculans 37.34 3.00e-29 121.00
IUUC-Laf-053720 Loxodonta africana 30.21 7.00e-19 87.00
IUUC-Mcc-055282 Macaca mulatta 30.00 4.00e-18 84.30
IUUC-Meu-056241 Macropus eugenii 34.55 1.00e-17 82.40
IUUC-Mor-057252 Magnaporthe oryzae 36.26 6.00e-32 130.00
IUUC-Mpo-057489 Magnaporthe poae 34.07 2.00e-30 125.00
IUUC-Mla-058940 Melampsora laricipopulina 27.31 3.00e-20 91.70
IUUC-Mga-059947 Meleagris gallopavo 30.77 2.00e-18 85.50
IUUC-Mvi-060388 Microbotryum violaceum 28.25 3.00e-15 74.70
IUUC-Mmr-060719 Microcebus murinus 28.63 7.00e-18 83.60
IUUC-Mdo-062352 Monodelphis domestica 33.93 9.00e-17 79.70
IUUC-Mmu-064340 Mus musculus 31.15 2.00e-19 88.60
IUUC-Mpu-066740 Mustela putorius furo 32.57 2.00e-18 85.90
IUUC-Mlu-068077 Myotis lucifugus 31.94 2.00e-18 85.50
IUUC-Nfi-068591 Neosartorya fischeri 39.41 8.00e-39 153.00
IUUC-Ncr-068787 Neurospora crassa 36.36 9.00e-32 130.00
IUUC-Nle-069942 Nomascus leucogenys 29.46 6.00e-18 84.00
IUUC-Opr-070597 Ochotona princeps 29.30 2.00e-17 82.40
IUUC-Ont-071776 Oreochromis niloticus 29.73 3.00e-15 74.70
IUUC-Oan-073604 Ornithorhynchus anatinus 32.35 2.00e-17 82.40
IUUC-Ocu-074698 Oryctolagus cuniculus 29.38 1.00e-18 85.90
IUUC-Ola-086446 Oryzias latipes 28.95 7.00e-14 70.10
IUUC-Oga-089080 Otolemur garnettii 31.55 2.00e-18 85.10
IUUC-Oar-089496 Ovis aries 29.52 9.00e-21 93.20
IUUC-Ptr-091203 Pan troglodytes 27.85 6.00e-18 84.00
IUUC-Pan-092673 Papio anubis 30.85 4.00e-17 81.30
IUUC-Psi-092992 Pelodiscus sinensis 29.80 1.00e-18 85.90
IUUC-Pma-094277 Petromyzon marinus 31.64 2.00e-18 85.10
IUUC-Pno-094971 Phaeosphaeria nodorum 38.12 2.00e-28 118.00
IUUC-Pfo-096790 Poecilia formosa 28.82 3.00e-16 78.60
IUUC-Pab-098734 Pongo abelii 30.89 3.00e-17 81.60
IUUC-Pca-100443 Procavia capensis 24.11 1.00e-09 55.80
IUUC-Pva-102788 Pteropus vampyrus 30.85 7.00e-18 83.60
IUUC-Pte-104098 Pyrenophora teres 37.04 2.00e-31 128.00
IUUC-Pyt-104561 Pyrenophora triticirepentis 36.56 8.00e-31 125.00
IUUC-Rno-105026 Rattus norvegicus 32.50 7.00e-20 90.10
IUUC-Sha-107229 Sarcophilus harrisii 31.34 2.00e-17 82.00
IUUC-Sja-107720 Schizosaccharomyces japonicus 48.72 1.00e-75 276.00
IUUC-Sar-113239 Sorex araneus 33.33 1.00e-14 72.80
IUUC-Ssc-115804 Sus scrofa 30.32 1.00e-16 79.70
IUUC-Tgu-116931 Taeniopygia guttata 31.76 6.00e-19 87.00
IUUC-Tru-117620 Takifugu rubripes 29.83 4.00e-15 74.30
IUUC-Tsy-118958 Tarsius syrichta 31.18 8.00e-19 86.70
IUUC-Tni-119683 Tetraodon nigroviridis 28.65 8.00e-14 70.10
IUUC-Tre-121884 Trichoderma reesei 32.12 9.00e-31 126.00
IUUC-Tvi-122552 Trichoderma virens 31.61 1.00e-30 126.00
IUUC-Tbe-127523 Tupaia belangeri 30.37 4.00e-17 81.30
IUUC-Ttr-128766 Tursiops truncatus 29.10 1.00e-19 89.40
IUUC-Vpa-130761 Vicugna pacos 28.28 8.00e-21 93.20
IUUC-Xtr-132031 Xenopus tropicalis 28.82 3.00e-15 74.70
IUUC-Xma-132984 Xiphophorus maculatus 25.67 1.00e-13 69.70
IUUC-Yli-134629 Yarrowia lipolytica 42.33 4.00e-37 147.00
Created Date 25-Jun-2017

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