iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059702

UUCD1 version

UUC-MeG-00827

Ensembl Protein ID

ENSMGAP00000015837.1

UniProt Accession

G1NPZ4; G1NPZ4_MELGA

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Gene Name

UCHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000014941.1	ENSMGAT00000016800.1	ENSMGAP00000015837.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.10e-60	205.5	2	213

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 21   lvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsvll 109
           +++++g++ d+q+ ++y+++pe l+++++pv+++lllF+i+ek+e++r+++   + ++ +++d+ ++++f+kq+i+N+C+t++l+++++
   Q: 2    FLKQLGIHPDWQFVDVYGMEPELLSMVPRPVCAVLLLFPITEKYETFRTEE--EERIKAKGQDVKSSVYFMKQTINNACGTIGLIHAIA 88
           789*********************************************766..5589******************************** PP
   S: 110  ncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglk 197
           n+ +k+ ++  + l++++e + ++ pe++a+ l++ ++++++h+s a+++++++p+ +       +k  +hf+++vn++g+lyeldg+k
   Q: 89   NNREKMnFETNSSLKKFLEDSLSMTPEERAKYLETYEAIRVTHESSAHEGQTEAPSID-------EKVDLHFIALVNVGGHLYELDGRK 170
           *******************************************************888.......8899******************** PP
   S: 198  pfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           pfP+++g+++++  l+d+++v+++f+er    + +e+rfn++a++a+
   Q: 171  PFPINHGETSDDSFLEDAIEVCKKFMER----DPEELRFNAIALSAA 213
           ****************************....9**********9875 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

QFLKQLGIHP DWQFVDVYGM EPELLSMVPR PVCAVLLLFP ITEKYETFRT EEEERIKAKG 60
QDVKSSVYFM KQTINNACGT IGLIHAIANN REKMNFETNS SLKKFLEDSL SMTPEERAKY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTTTCTCA AGCAGTTAGG TATACATCCT GACTGGCAAT TTGTAGATGT CTATGGTATG 60
GAACCGGAAC TGCTTAGCAT GGTGCCAAGA CCTGTATGTG CAGTGCTTCT TCTCTTTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	38.46	2.00e-39	155.00
IUUC-Aml-001344	Ailuropoda melanoleuca	86.85	7.00e-107	379.00
IUUC-Atr-002931	Amborella trichopoda	45.75	4.00e-45	173.00
IUUC-Apl-003949	Anas platyrhynchos	99.53	6.00e-116	409.00
IUUC-Aca-004924	Anolis carolinensis	86.85	4.00e-106	376.00
IUUC-Ath-006827	Arabidopsis thaliana	49.06	1.00e-47	182.00
IUUC-Ago-007950	Ashbya gossypii	34.12	7.00e-25	106.00
IUUC-Acl-008305	Aspergillus clavatus	36.20	9.00e-34	136.00
IUUC-Afl-008611	Aspergillus flavus	37.10	4.00e-35	140.00
IUUC-Afu-008945	Aspergillus fumigatus	36.77	1.00e-33	135.00
IUUC-Ani-009339	Aspergillus nidulans	36.49	3.00e-34	138.00
IUUC-Ang-009691	Aspergillus niger	35.29	2.00e-33	135.00
IUUC-Aor-009961	Aspergillus oryzae	37.10	5.00e-35	140.00
IUUC-Ate-010316	Aspergillus terreus	36.94	4.00e-35	140.00
IUUC-Ame-011157	Astyanax mexicanus	74.18	5.00e-90	323.00
IUUC-Bgr-012125	Blumeria graminis	33.18	3.00e-30	124.00
IUUC-Bta-012673	Bos taurus	86.38	3.00e-106	376.00
IUUC-Bci-013734	Botrytis cinerea	36.53	5.00e-33	134.00
IUUC-Bdi-014330	Brachypodium distachyon	41.51	2.00e-43	168.00
IUUC-Bol-015214	Brassica oleracea	48.58	2.00e-48	184.00
IUUC-Bra-017491	Brassica rapa	49.06	5.00e-48	183.00
IUUC-Cfa-020371	Canis familiaris	83.68	3.00e-89	320.00
IUUC-Cpo-022036	Cavia porcellus	84.51	1.00e-102	365.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	42.29	7.00e-27	113.00
IUUC-Csa-023854	Chlorocebus sabaeus	85.92	4.00e-105	373.00
IUUC-Cin-025545	Ciona intestinalis	48.34	4.00e-58	217.00
IUUC-Cgl-026659	Colletotrichum gloeosporioides	31.65	2.00e-23	101.00
IUUC-Cne-026914	Cryptococcus neoformans	36.11	4.00e-26	110.00
IUUC-Cme-027216	Cyanidioschyzon merolae	39.49	3.00e-24	104.00
IUUC-Dre-028356	Danio rerio	73.71	7.00e-89	319.00
IUUC-Dse-031461	Dothistroma septosporum	36.32	8.00e-28	116.00
IUUC-Dme-032146	Drosophila melanogaster	49.77	2.00e-53	201.00
IUUC-Eca-033220	Equus caballus	86.38	6.00e-106	375.00
IUUC-Fca-036421	Felis catus	86.85	7.00e-107	379.00
IUUC-Fal-036773	Ficedula albicollis	99.53	7.00e-116	409.00
IUUC-Fox-037830	Fusarium oxysporum	35.29	5.00e-34	137.00
IUUC-Fso-038259	Fusarium solani	33.64	2.00e-29	124.00
IUUC-Gmo-039468	Gadus morhua	69.67	5.00e-75	273.00
IUUC-Ggr-039832	Gaeumannomyces graminis	34.72	4.00e-28	117.00
IUUC-Gga-041205	Gallus gallus	100.00	4.00e-116	409.00
IUUC-Gac-041629	Gasterosteus aculeatus	70.14	1.00e-81	295.00
IUUC-Ggo-044533	Gorilla gorilla	86.85	6.00e-107	379.00
IUUC-Hsa-046754	Homo sapiens	86.85	7.00e-107	379.00
IUUC-Hvu-047176	Hordeum vulgare	37.85	3.00e-35	140.00
IUUC-Itr-047992	Ictidomys tridecemlineatus	84.40	4.00e-66	242.00
IUUC-Kpa-049123	Komagataella pastoris	33.85	3.00e-23	101.00
IUUC-Lch-049685	Latimeria chalumnae	76.78	4.00e-95	340.00
IUUC-Loc-051988	Lepisosteus oculatus	75.59	2.00e-93	334.00
IUUC-Lma-053316	Leptosphaeria maculans	40.09	3.00e-38	151.00
IUUC-Laf-053985	Loxodonta africana	85.45	2.00e-105	374.00
IUUC-Mcc-055888	Macaca mulatta	85.85	7.00e-105	372.00
IUUC-Mor-057271	Magnaporthe oryzae	36.07	3.00e-33	134.00
IUUC-Mla-058942	Melampsora laricipopulina	45.00	3.00e-35	140.00
IUUC-Mvi-060249	Microbotryum violaceum	42.00	3.00e-32	131.00
IUUC-Mmr-061284	Microcebus murinus	84.40	3.00e-65	241.00
IUUC-Mdo-062639	Monodelphis domestica	75.60	7.00e-103	365.00
IUUC-Mmu-063299	Mus musculus	86.85	1.00e-106	378.00
IUUC-Mac-065075	Musa acuminata	44.19	1.00e-42	165.00
IUUC-Mpu-066769	Mustela putorius furo	86.85	7.00e-107	379.00
IUUC-Mlu-066937	Myotis lucifugus	85.92	1.00e-105	374.00
IUUC-Nfi-068320	Neosartorya fischeri	37.22	1.00e-34	139.00
IUUC-Ncr-068673	Neurospora crassa	36.99	3.00e-36	144.00
IUUC-Nle-069175	Nomascus leucogenys	86.79	1.00e-105	374.00
IUUC-Ont-072170	Oreochromis niloticus	72.51	4.00e-84	303.00
IUUC-Oan-073247	Ornithorhynchus anatinus	88.54	3.00e-42	162.00
IUUC-Ocu-074422	Oryctolagus cuniculus	86.38	3.00e-106	377.00
IUUC-Obr-076041	Oryza brachyantha	40.38	3.00e-42	164.00
IUUC-Ogl-076980	Oryza glaberrima	40.85	8.00e-42	162.00
IUUC-Olo-080671	Oryza longistaminata	38.86	2.00e-38	152.00
IUUC-Ome-081428	Oryza meridionalis	37.91	4.00e-37	147.00
IUUC-Opu-083305	Oryza punctata	38.86	7.00e-38	149.00
IUUC-Osa-085830	Oryza sativa	40.85	8.00e-42	162.00
IUUC-Ola-086893	Oryzias latipes	70.14	5.00e-80	289.00
IUUC-Olu-087858	Ostreococcus lucimarinus	40.57	7.00e-40	156.00
IUUC-Oga-088055	Otolemur garnettii	86.85	6.00e-107	379.00
IUUC-Oar-090319	Ovis aries	86.38	3.00e-106	377.00
IUUC-Pan-092714	Papio anubis	85.92	1.00e-105	375.00
IUUC-Psi-094036	Pelodiscus sinensis	93.90	8.00e-112	395.00
IUUC-Pma-094412	Petromyzon marinus	63.83	4.00e-47	179.00
IUUC-Pno-094997	Phaeosphaeria nodorum	33.89	1.00e-23	102.00
IUUC-Ppa-095519	Physcomitrella patens	47.39	4.00e-53	200.00
IUUC-Pfo-096182	Poecilia formosa	69.48	2.00e-81	294.00
IUUC-Pab-098216	Pongo abelii	86.11	3.00e-73	266.00
IUUC-Pop-099282	Populus trichocarpa	43.87	1.00e-39	155.00
IUUC-Ppe-101332	Prunus persica	44.34	7.00e-45	173.00
IUUC-Pgr-103430	Puccinia graminis	45.45	1.00e-40	159.00
IUUC-Ptt-103955	Puccinia triticina	48.13	5.00e-42	163.00
IUUC-Pte-104414	Pyrenophora teres	36.53	3.00e-30	124.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	32.29	8.00e-27	113.00
IUUC-Rno-105096	Rattus norvegicus	85.45	2.00e-105	374.00
IUUC-Sce-106412	Saccharomyces cerevisiae	32.00	2.00e-22	98.20
IUUC-Sha-106677	Sarcophilus harrisii	88.73	2.00e-108	384.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	27.92	2.00e-17	81.60
IUUC-Spo-108322	Schizosaccharomyces pombe	32.34	1.00e-21	95.90
IUUC-Ssl-108641	Sclerotinia sclerotiorum	35.87	1.00e-32	132.00
IUUC-Smo-109283	Selaginella moellendorffii	44.95	4.00e-42	164.00
IUUC-Sit-110163	Setaria italica	42.25	1.00e-42	166.00
IUUC-Sly-111613	Solanum lycopersicum	47.17	6.00e-50	189.00
IUUC-Sbi-114545	Sorghum bicolor	41.12	1.00e-40	158.00
IUUC-Sre-114961	Sporisorium reilianum	40.58	2.00e-29	122.00
IUUC-Ssc-115255	Sus scrofa	85.85	6.00e-105	372.00
IUUC-Tgu-117003	Taeniopygia guttata	99.53	1.00e-115	408.00
IUUC-Tru-118330	Takifugu rubripes	65.66	1.00e-59	223.00
IUUC-Tni-120042	Tetraodon nigroviridis	66.47	5.00e-60	225.00
IUUC-Tca-120976	Theobroma cacao	45.75	1.00e-46	179.00
IUUC-Tre-122149	Trichoderma reesei	37.79	6.00e-36	143.00
IUUC-Tvi-122450	Trichoderma virens	38.53	1.00e-35	142.00
IUUC-Tur-126250	Triticum urartu	38.46	5.00e-39	153.00
IUUC-Tme-126961	Tuber melanosporum	36.53	1.00e-29	122.00
IUUC-Uma-129382	Ustilago maydis	40.58	5.00e-33	133.00
IUUC-Vda-129850	Verticillium dahliae	31.02	9.00e-24	103.00
IUUC-Vvi-131661	Vitis vinifera	42.45	3.00e-43	167.00
IUUC-Xtr-132428	Xenopus tropicalis	71.83	9.00e-91	325.00
IUUC-Xma-134245	Xiphophorus maculatus	69.05	2.00e-81	294.00
IUUC-Yli-134570	Yarrowia lipolytica	38.65	1.00e-31	129.00
IUUC-Zma-134740	Zea mays	40.65	2.00e-42	164.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence