iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134528

Ensembl Protein ID

CAG83757

UniProt Accession

Q6CHN0; SLA1_YARLI

Genbank Protein ID

CAG83757.1

Protein Name

Actin cytoskeleton-regulatory complex protein SLA1

Genbank Nucleotide ID

CR382127

Gene Name

SLA1; YALI0A07018g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_A07018g	CAG83757	CAG83757

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-36	122.7	359	413

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++ +vly ++aq  de + ++G+ v++i +++++ +W++  k+ +g  G++P+ ++e
   Q: 359  KLGKVLYKFDAQGRDEVSVEEGENVFII-DDTKSRDWWMV-KNSSGVAGVVPSSYIE 413
           6789************************.*********98.7*************98 PP

Organism

Yarrowia lipolytica

Functional Description
(View)

Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).

Protein Sequence
(Fasta)

MPSLFHGVYQ ALYDYEARTE DELTFSENSL LYLLEKSSTD EWLKAKKAGP AGTNEIGLVP 60
LTYIEPAPAK RQAYALYDYD KQTEEELTFK EGDALTVYDD SDSEWLLVCR GGDEYGFVPA 120

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Nucleotide Sequence
(Fasta)

ATGCCGTCTC TGTTCCACGG CGTGTACCAA GCGCTCTACG ACTATGAGGC TCGTACGGAG 60
GACGAATTGA CCTTTTCCGA GAACTCGCTT CTCTACCTTT TGGAAAAGTC GTCGACCGAC 120

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Sequence Source

Ensembl

Keyword

KW-0009--Actin-binding
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0254--Endocytosis
KW-0967--Endosome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain

Interpro

IPR013761--SAM/pointed
IPR001452--SH3_domain
IPR007131--SHD1
IPR029922--Sla1

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF03983--SHD1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0030479--C:actin cortical patch
GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0007015--P:actin filament organization
GO:0006897--P:endocytosis

KEGG

yli:YALI0A07018g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007979	Ashbya gossypii	40.07	6.00e-59	220.00
IUUC-Acl-008300	Aspergillus clavatus	43.76	2.00e-86	311.00
IUUC-Afl-008694	Aspergillus flavus	41.06	5.00e-71	261.00
IUUC-Afu-008881	Aspergillus fumigatus	43.47	2.00e-83	301.00
IUUC-Ani-009274	Aspergillus nidulans	45.54	1.00e-84	306.00
IUUC-Ang-009534	Aspergillus niger	44.24	1.00e-92	333.00
IUUC-Aor-010097	Aspergillus oryzae	46.75	1.00e-81	296.00
IUUC-Ate-010495	Aspergillus terreus	44.75	4.00e-86	311.00
IUUC-Ame-011670	Astyanax mexicanus	48.28	4.00e-09	53.50
IUUC-Bgr-012294	Blumeria graminis	42.70	3.00e-89	321.00
IUUC-Bci-013990	Botrytis cinerea	47.14	4.00e-42	165.00
IUUC-Cel-018144	Caenorhabditis elegans	45.28	8.00e-10	55.80
IUUC-Csv-025910	Ciona savignyi	31.09	2.00e-10	55.50
IUUC-Cgl-026697	Colletotrichum gloeosporioides	51.43	3.00e-48	185.00
IUUC-Cne-026842	Cryptococcus neoformans	36.33	1.00e-36	146.00
IUUC-Dre-028211	Danio rerio	47.27	1.00e-09	57.00
IUUC-Dor-030295	Dipodomys ordii	49.09	1.00e-09	57.00
IUUC-Dse-031496	Dothistroma septosporum	39.57	2.00e-76	279.00
IUUC-Fal-036698	Ficedula albicollis	45.45	5.00e-09	54.70
IUUC-Fso-038358	Fusarium solani	41.08	7.00e-81	293.00
IUUC-Ggr-040032	Gaeumannomyces graminis	41.47	2.00e-74	272.00
IUUC-Kpa-049118	Komagataella pastoris	39.80	6.00e-51	194.00
IUUC-Lma-053236	Leptosphaeria maculans	52.54	2.00e-46	178.00
IUUC-Mor-056954	Magnaporthe oryzae	44.57	8.00e-89	320.00
IUUC-Mpo-057576	Magnaporthe poae	48.56	1.00e-49	189.00
IUUC-Mla-059035	Melampsora laricipopulina	43.89	3.00e-34	139.00
IUUC-Mvi-060454	Microbotryum violaceum	39.78	4.00e-30	125.00
IUUC-Mpu-066414	Mustela putorius furo	47.27	2.00e-08	53.50
IUUC-Nfi-068406	Neosartorya fischeri	43.63	5.00e-83	301.00
IUUC-Ncr-068902	Neurospora crassa	37.25	1.00e-52	199.00
IUUC-Opr-070603	Ochotona princeps	49.09	9.00e-10	57.40
IUUC-Ome-081785	Oryza meridionalis	56.25	1.90e-01	27.30
IUUC-Oga-088492	Otolemur garnettii	47.27	4.00e-09	55.50
IUUC-Pno-094774	Phaeosphaeria nodorum	42.14	5.00e-78	284.00
IUUC-Pca-100736	Procavia capensis	50.91	3.00e-09	55.80
IUUC-Pgr-103396	Puccinia graminis	42.86	2.00e-34	139.00
IUUC-Ptt-103751	Puccinia triticina	40.54	4.00e-35	141.00
IUUC-Pte-104349	Pyrenophora teres	52.43	7.00e-45	174.00
IUUC-Pyt-104695	Pyrenophora triticirepentis	50.23	6.00e-43	167.00
IUUC-Sce-106372	Saccharomyces cerevisiae	44.79	2.00e-39	156.00
IUUC-Sja-107962	Schizosaccharomyces japonicus	33.70	9.00e-65	240.00
IUUC-Spo-108375	Schizosaccharomyces pombe	32.02	1.00e-22	100.00
IUUC-Ssl-108553	Sclerotinia sclerotiorum	41.34	3.00e-73	268.00
IUUC-Sit-109721	Setaria italica	47.06	6.20e-01	25.40
IUUC-Sre-115072	Sporisorium reilianum	54.32	4.00e-23	101.00
IUUC-Tru-118643	Takifugu rubripes	45.45	3.00e-08	52.40
IUUC-Tre-121912	Trichoderma reesei	41.97	1.00e-71	263.00
IUUC-Tvi-122336	Trichoderma virens	47.71	3.00e-45	175.00
IUUC-Tme-127017	Tuber melanosporum	40.43	3.00e-50	191.00
IUUC-Tbe-127262	Tupaia belangeri	44.23	2.00e-09	55.10
IUUC-Uma-129502	Ustilago maydis	60.87	7.00e-23	101.00
IUUC-Vda-129879	Verticillium dahliae	43.54	8.00e-82	296.00
IUUC-Xtr-132625	Xenopus tropicalis	44.44	6.00e-09	53.50

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence