iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007962

Ensembl Protein ID

AAS53358

UniProt Accession

Q754T5; Q754T5_ASHGO

Genbank Protein ID

AAS53358.1

Protein Name

AFL014Cp

Genbank Nucleotide ID

AE016819

Gene Name

AGOS_AFL014C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AFL014C	AAS53358	AAS53358

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	7.90e-121	401.0	211	520
E3 adaptor/Cullin RING/DCX/DWD	2.20e-24	82.5	346	381

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladleekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtl.tghsarvg 100
           pe++ldap ++ddfylnLl+Ws+knvla+aL++s+ylw+ +tg+vs l+++ e++++tsv w+++++++++G+++g++ei+Dve++++vrt+ ++   r++
   Q: 211  PERILDAPGFQDDFYLNLLSWSKKNVLAIALDQSIYLWNGETGEVSLLTEF-ETETITSVVWSNDDCHISIGKDDGNTEIWDVETMSHVRTMrSSLGVRIC 310
           689************************************************.999*************************************88899**** PP
   S: 101  aLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfkehkaavkaiawsPwqkslLasGGGt 201
           + +W ++v++ G ++gei+ +dvrvk++ +st+++h++evCG+k+++d+ +LasGGnDn+v++wd+++ ePl  +++h+aavkai+w P   +lLa+GGG+
   Q: 311  SQDWLDTVVCIGAKSGEIQVNDVRVKDHIVSTWEKHTSEVCGIKFRQDGLQLASGGNDNTVMIWDTRQDEPLWVKRNHNAAVKAITWHPDVVNLLATGGGS 411
           ***************************************************************************************************** PP
   S: 202  aDrcikfwntltgalleeidtgsqvcsllwskks......kelvsthGfaenkitlwkypslskvae.lkgheaRvlslalspdgeaivtaagDetlrfwk 295
            Dr+i+fwnt+tga++ +i+tgsqv+sl+w++++      +e+v+t G ++n+i++++y+s+ kvae  ++he+R++s++lspdg++i+t++gDe+l+f++
   Q: 412  LDRHIHFWNTTTGARIGSINTGSQVSSLHWGQSYedshmnREIVATGGSPDNSISIYNYDSKVKVAEiTQAHESRIVSSQLSPDGTTIATVGGDENLKFYR 512
           *******************************9998889989**************************889******************************* PP
   S: 296  lfdkkkak 303
           +fd k++k
   Q: 513  VFDAKRKK 520
           ***99876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           Ht++v++++f +d   l+sG++D+t+++WD+r++ +
   Q: 346  HTSEVCGIKFrQDgLQLASGGNDNTVMIWDTRQDEP 381
           ***********88788***************99876 PP

Organism

Ashbya gossypii

Protein Sequence
(Fasta)

MVDTKEPRLS ASRSMLLLSS PSRLNVVSSD WSKVEKHNKV MKPRAAHGSL SNVTNVAHSA 60
GGGMQRTKLT QAVPPLLRKS SSYFKEEAVK EAAAEEHGSQ TYASSDRFIP VRNKGTGARC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGACA CGAAGGAGCC GCGGCTCAGT GCAAGCAGGT CGATGCTGCT GCTCTCGTCG 60
CCGTCGAGGC TCAACGTGGT GTCGTCGGAC TGGTCGAAGG TGGAGAAGCA CAACAAGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0033597--C:mitotic checkpoint complex
GO:0034399--C:nuclear periphery
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0045732--P:positive regulation of protein catabolic process
GO:0051441--P:positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle
GO:0040020--P:regulation of meiotic nuclear division

KEGG

ago:AGOS_AFL014C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008043	Aspergillus clavatus	45.10	3.00e-89	320.00
IUUC-Afl-008593	Aspergillus flavus	45.93	4.00e-90	323.00
IUUC-Afu-008793	Aspergillus fumigatus	43.53	3.00e-89	320.00
IUUC-Ani-009158	Aspergillus nidulans	44.04	4.00e-89	320.00
IUUC-Ang-009786	Aspergillus niger	46.67	1.00e-88	318.00
IUUC-Aor-010163	Aspergillus oryzae	45.93	4.00e-90	323.00
IUUC-Ate-010479	Aspergillus terreus	43.59	1.00e-90	325.00
IUUC-Bgr-012059	Blumeria graminis	47.72	5.00e-98	349.00
IUUC-Bci-013607	Botrytis cinerea	46.62	2.00e-96	344.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	44.20	5.00e-95	339.00
IUUC-Cne-026872	Cryptococcus neoformans	44.65	1.00e-83	301.00
IUUC-Dse-031391	Dothistroma septosporum	47.18	2.00e-95	340.00
IUUC-Fox-037850	Fusarium oxysporum	45.28	2.00e-92	331.00
IUUC-Fso-038375	Fusarium solani	43.58	9.00e-93	332.00
IUUC-Ggr-039864	Gaeumannomyces graminis	44.86	2.00e-96	343.00
IUUC-Lma-052998	Leptosphaeria maculans	46.52	5.00e-93	333.00
IUUC-Mor-057277	Magnaporthe oryzae	45.36	6.00e-94	335.00
IUUC-Mpo-057624	Magnaporthe poae	44.33	1.00e-92	331.00
IUUC-Mla-059066	Melampsora laricipopulina	37.74	3.00e-74	270.00
IUUC-Mvi-060422	Microbotryum violaceum	39.95	7.00e-79	285.00
IUUC-Nfi-068375	Neosartorya fischeri	43.76	2.00e-89	321.00
IUUC-Ncr-068951	Neurospora crassa	45.72	2.00e-93	334.00
IUUC-Pno-094809	Phaeosphaeria nodorum	45.14	7.00e-95	338.00
IUUC-Pgr-103627	Puccinia graminis	39.49	3.00e-71	260.00
IUUC-Pte-104142	Pyrenophora teres	45.48	5.00e-92	329.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	45.48	7.00e-92	328.00
IUUC-Sce-106360	Saccharomyces cerevisiae	54.31	5.00e-177	612.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	43.78	7.00e-96	342.00
IUUC-Spo-108075	Schizosaccharomyces pombe	41.75	5.00e-94	335.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	46.85	4.00e-96	343.00
IUUC-Sre-114976	Sporisorium reilianum	39.95	2.00e-70	257.00
IUUC-Tre-122211	Trichoderma reesei	43.11	1.00e-92	331.00
IUUC-Tvi-122531	Trichoderma virens	44.33	5.00e-95	339.00
IUUC-Tme-126905	Tuber melanosporum	45.80	7.00e-97	345.00
IUUC-Uma-129318	Ustilago maydis	43.24	1.00e-70	258.00
IUUC-Vda-129993	Verticillium dahliae	45.81	2.00e-95	340.00
IUUC-Yli-134501	Yarrowia lipolytica	43.37	2.00e-98	350.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence