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Tag Content
iUUCD ID IUUC-Psi-093792
Ensembl Protein ID ENSPSIP00000019457.1
UniProt Accession K7GGP6; K7GGP6_PELSI
Genbank Protein ID ENSPSIP00000019457
Protein Name tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4
Genbank Nucleotide ID AGCU01194773
Gene Name WDR4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPSIG00000017237.1 ENSPSIT00000019541.1 ENSPSIP00000019450.1
ENSPSIG00000017237.1 ENSPSIT00000019548.1 ENSPSIP00000019457.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.80e-07 31.3 199 233
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 6    vtclaf..sd..tllvsGsdDgtikvWDlrtgvllk 37
           v+ + f  ++  +l++s+s+D+t+++W++++g+ ++
   Q: 199  VSRI-FviPNfpDLMLSASGDCTLRLWEYKSGKEVQ 233
           4444.4664445899***************999876 PP
   
Organism Pelodiscus sinensis
Functional Description
(View)

Functional Description


     Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
 Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Protein Sequence
(Fasta)
MEAAGAGSRG PGLALCGGLM AASGGSRFLA ARYQEPSMDD LFMYDCITAG KKSQEDRGQD 60
GQPAIKTSDD ILTFAFSSSG DYFAVTDDNK RLILFRTKPC WECLSVRSVV RRCTSLIITS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Psi-093792|E3,WD_repeat|Pelodiscus sinensis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCGCAGCTG GGGGCGCGCA CGTGGGCGGC TGTGTGCATG GATGGAGGCG GCGGGGGCTG 60
GAAGTCGCGG CCCGGGGCTG GCGCTCTGCG GAGGCCTGAT GGCTGCCAGC GGCGGGAGTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Psi-093792|E3,WD_repeat|Pelodiscus sinensis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat
Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
SMART

SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003975 Anas platyrhynchos 75.29 2.00e-158 551.00
IUUC-Aca-005170 Anolis carolinensis 73.21 1.00e-145 509.00
IUUC-Aly-005769 Arabidopsis lyrata 29.14 4.00e-23 102.00
IUUC-Ath-006733 Arabidopsis thaliana 30.58 1.00e-23 103.00
IUUC-Acl-008151 Aspergillus clavatus 28.63 3.00e-15 76.60
IUUC-Afl-008518 Aspergillus flavus 41.24 2.00e-13 69.70
IUUC-Afu-009102 Aspergillus fumigatus 29.25 2.00e-13 70.50
IUUC-Ani-009442 Aspergillus nidulans 26.89 4.00e-13 69.30
IUUC-Aor-010133 Aspergillus oryzae 29.32 2.00e-16 80.50
IUUC-Ate-010465 Aspergillus terreus 28.45 4.00e-14 72.40
IUUC-Ame-010613 Astyanax mexicanus 42.74 7.00e-89 320.00
IUUC-Bgr-012067 Blumeria graminis 35.37 3.00e-17 83.20
IUUC-Bta-012788 Bos taurus 58.70 2.00e-131 462.00
IUUC-Bdi-014458 Brachypodium distachyon 29.32 1.00e-15 77.40
IUUC-Bol-016398 Brassica oleracea 30.42 3.00e-24 105.00
IUUC-Bra-017059 Brassica rapa 35.96 5.00e-22 98.20
IUUC-Cpo-021963 Cavia porcellus 56.15 6.00e-124 436.00
IUUC-Csa-024148 Chlorocebus sabaeus 60.05 1.00e-116 412.00
IUUC-Cne-026834 Cryptococcus neoformans 31.15 4.00e-17 82.80
IUUC-Dre-028427 Danio rerio 47.56 6.00e-91 327.00
IUUC-Dno-028881 Dasypus novemcinctus 53.03 2.00e-117 415.00
IUUC-Dor-030522 Dipodomys ordii 57.80 5.00e-128 450.00
IUUC-Dme-032136 Drosophila melanogaster 42.60 1.00e-25 110.00
IUUC-Fca-035833 Felis catus 61.08 3.00e-131 461.00
IUUC-Fal-037497 Ficedula albicollis 75.15 4.00e-154 537.00
IUUC-Gga-040547 Gallus gallus 72.63 1.00e-157 548.00
IUUC-Gac-041761 Gasterosteus aculeatus 39.68 5.00e-78 284.00
IUUC-Gma-043722 Glycine max 27.90 2.00e-20 92.80
IUUC-Ggo-045340 Gorilla gorilla 58.97 6.00e-122 430.00
IUUC-Hsa-046403 Homo sapiens 59.51 1.00e-122 432.00
IUUC-Hvu-047643 Hordeum vulgare 28.57 2.00e-15 76.60
IUUC-Itr-048103 Ictidomys tridecemlineatus 57.34 2.00e-131 462.00
IUUC-Kpa-049283 Komagataella pastoris 28.43 7.00e-16 77.80
IUUC-Lch-050682 Latimeria chalumnae 54.68 4.00e-120 424.00
IUUC-Lpe-050712 Leersia perrieri 29.39 2.00e-22 99.80
IUUC-Loc-052599 Lepisosteus oculatus 54.22 2.00e-116 411.00
IUUC-Laf-054390 Loxodonta africana 62.23 9.00e-140 489.00
IUUC-Mcc-054747 Macaca mulatta 59.24 1.00e-120 426.00
IUUC-Mtr-058600 Medicago truncatula 28.16 2.00e-23 102.00
IUUC-Mla-059129 Melampsora laricipopulina 27.12 5.00e-13 67.80
IUUC-Mga-059876 Meleagris gallopavo 73.98 1.00e-155 541.00
IUUC-Mvi-060359 Microbotryum violaceum 35.22 9.00e-15 75.10
IUUC-Mmr-061518 Microcebus murinus 58.42 1.00e-127 449.00
IUUC-Mac-065625 Musa acuminata 28.63 7.00e-21 94.70
IUUC-Nfi-068402 Neosartorya fischeri 28.06 3.00e-13 69.30
IUUC-Nle-069914 Nomascus leucogenys 58.15 7.00e-116 410.00
IUUC-Ont-071555 Oreochromis niloticus 40.53 2.00e-81 296.00
IUUC-Oan-072951 Ornithorhynchus anatinus 66.57 1.00e-139 489.00
IUUC-Ocu-074679 Oryctolagus cuniculus 58.15 2.00e-126 445.00
IUUC-Oba-075355 Oryza barthii 25.65 2.00e-11 63.50
IUUC-Obr-076769 Oryza brachyantha 30.12 5.00e-23 101.00
IUUC-Ogl-077168 Oryza glaberrima 29.26 9.00e-23 100.00
IUUC-Ogu-078275 Oryza glumaepatula 26.56 2.00e-11 63.90
IUUC-Oin-079207 Oryza indica 29.26 9.00e-23 100.00
IUUC-Oni-082437 Oryza nivara 25.65 3.00e-11 63.20
IUUC-Opu-084031 Oryza punctata 29.45 3.00e-21 96.30
IUUC-Oru-084380 Oryza rufipogon 26.56 5.00e-11 62.00
IUUC-Osa-085327 Oryza sativa 29.26 2.00e-22 99.40
IUUC-Ola-086716 Oryzias latipes 38.62 4.00e-73 268.00
IUUC-Olu-087708 Ostreococcus lucimarinus 25.71 5.00e-14 71.60
IUUC-Oar-090239 Ovis aries 58.60 1.00e-130 459.00
IUUC-Ptr-090851 Pan troglodytes 59.24 1.00e-122 432.00
IUUC-Pan-092558 Papio anubis 59.73 3.00e-115 408.00
IUUC-Ppa-095757 Physcomitrella patens 36.69 3.00e-19 89.40
IUUC-Pfo-096465 Poecilia formosa 40.74 2.00e-82 298.00
IUUC-Pab-097722 Pongo abelii 59.25 1.00e-122 432.00
IUUC-Pop-098979 Populus trichocarpa 30.18 2.00e-18 86.30
IUUC-Pca-100753 Procavia capensis 59.68 4.00e-92 331.00
IUUC-Ppe-101515 Prunus persica 26.72 5.00e-17 82.00
IUUC-Sja-107780 Schizosaccharomyces japonicus 26.79 7.00e-13 68.20
IUUC-Spo-108251 Schizosaccharomyces pombe 28.70 2.00e-12 67.00
IUUC-Smo-108938 Selaginella moellendorffii 33.33 5.00e-17 82.00
IUUC-Sit-110020 Setaria italica 28.46 2.00e-19 89.70
IUUC-Sly-111543 Solanum lycopersicum 27.93 2.00e-23 103.00
IUUC-Stu-111925 Solanum tuberosum 27.93 3.00e-23 102.00
IUUC-Sbi-114061 Sorghum bicolor 28.74 4.00e-21 95.50
IUUC-Tgu-117321 Taeniopygia guttata 73.90 3.00e-142 497.00
IUUC-Tru-118454 Takifugu rubripes 40.37 3.00e-77 281.00
IUUC-Tni-119894 Tetraodon nigroviridis 40.46 7.00e-69 253.00
IUUC-Tca-121746 Theobroma cacao 31.91 9.00e-19 87.80
IUUC-Tae-123054 Triticum aestivum 28.46 5.00e-16 78.60
IUUC-Tur-126254 Triticum urartu 29.88 8.00e-08 51.20
IUUC-Tbe-127683 Tupaia belangeri 39.33 1.00e-41 163.00
IUUC-Ttr-129056 Tursiops truncatus 55.98 2.00e-122 432.00
IUUC-Vvi-131428 Vitis vinifera 32.62 1.00e-19 90.90
IUUC-Xma-133605 Xiphophorus maculatus 40.58 1.00e-82 299.00
Created Date 25-Jun-2017

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