iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044947

UUCD1 version

UUC-GoG-01116

Ensembl Protein ID

ENSGGOP00000005255.2

UniProt Accession

G3QRK0; G3QRK0_GORGO

Protein Name

Uncharacterized protein

Gene Name

USP7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000005355.2	ENSGGOT00000005392.2	ENSGGOP00000005255.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-68	231.8	222	528

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+g+tCYmNS+LQ+L+++++lr+++    + +      +++++++  +lq++f el ++++k v +++l+k++++e   +++++q
   Q: 222  VGLKNQGATCYMNSLLQTLFFTNQLRKAVYM-MPTEG-----DDSSKSVPLALQRVFYEL-QHSDKPVGTKKLTKSFGWET--LDSFMQ 301
           6******************************.44433.....466889************.88889************887..67**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++lld++e+++                          k +  + +i +lF+g++ s i+c+e d +s r+e+ +d++l+++g
   Q: 302  HDVQELCRVLLDNVENKM--------------------------KGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKG 364
           ******************..........................789****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           k+     ++ +++ ++++ e+l+g+nky   +  ++qeaek +k+ +lP+vL+l+L+Rf ++ ++++++kin+++efp++L l++f+++
   Q: 365  KK-----NIFESFVDYVAVEQLDGDNKYDAGEH-GLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQK 447
           **.....9*********************9996.7****************************************************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg............staYvlfYkr 337
           ++ k+  + +Y L+av+vHsG  ++GHYv+y +   +gkW++fdD+ V+ +++ee  e +             ++aY+l+Y r
   Q: 448  TDPKD--PANYILHAVLVHSGDNHGGHYVVYLNPkGDGKWCKFDDDVVSRCTKEEAIEHNYgghdddlsvrhcTNAYMLVYIR 528
           88777..*************************9834566************86666664446*******************87 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

CSHSDVGERT SPIPQQTPLQ SHAEMAGNHR LGLEAGDTDD PPRITQNPVI NGNVALSDGH 60
NNAEEDMEDD TSWRSEATFQ FTVERFSRLS ESVLSPPCFV RNLPWKIMVM PRFYPDRPHQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAATAAA AAAGAATGCT GAGGTAGAGC TCCTAGAGAT TCTATGCAGT CACTCTGATG 60
TGGGTGAGAG AACCTCCCCC ATCCCCCAGC AGACGCCACT GCAGAGCCAT GCAGAGATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0010216--P:maintenance of DNA methylation
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0050821--P:protein stabilization
GO:0006283--P:transcription-coupled nucleotide-excision repair
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	33.21	6.00e-143	501.00
IUUC-Aml-002408	Ailuropoda melanoleuca	98.38	0.00e+00	2249.00
IUUC-Atr-003067	Amborella trichopoda	36.73	7.00e-123	435.00
IUUC-Apl-003558	Anas platyrhynchos	96.85	0.00e+00	2198.00
IUUC-Aca-004518	Anolis carolinensis	91.15	0.00e+00	2060.00
IUUC-Aly-006453	Arabidopsis lyrata	36.91	2.00e-160	559.00
IUUC-Ath-006591	Arabidopsis thaliana	36.33	2.00e-156	546.00
IUUC-Ago-007849	Ashbya gossypii	32.88	2.00e-139	490.00
IUUC-Acl-008327	Aspergillus clavatus	33.92	5.00e-170	592.00
IUUC-Afl-008491	Aspergillus flavus	34.57	3.00e-164	572.00
IUUC-Afu-008804	Aspergillus fumigatus	34.94	2.00e-161	563.00
IUUC-Ang-009776	Aspergillus niger	34.69	3.00e-161	562.00
IUUC-Aor-009998	Aspergillus oryzae	33.83	1.00e-155	544.00
IUUC-Ate-010428	Aspergillus terreus	34.51	9.00e-164	571.00
IUUC-Ame-010903	Astyanax mexicanus	93.19	0.00e+00	2129.00
IUUC-Bgr-012132	Blumeria graminis	32.10	5.00e-144	505.00
IUUC-Bta-013192	Bos taurus	98.61	0.00e+00	2210.00
IUUC-Bci-013924	Botrytis cinerea	33.94	2.00e-150	526.00
IUUC-Bdi-014920	Brachypodium distachyon	35.73	7.00e-157	548.00
IUUC-Bol-015224	Brassica oleracea	36.68	4.00e-157	549.00
IUUC-Bra-017448	Brassica rapa	36.46	7.00e-157	548.00
IUUC-Cel-018219	Caenorhabditis elegans	33.95	1.00e-155	543.00
IUUC-Cja-019006	Callithrix jacchus	98.11	0.00e+00	2244.00
IUUC-Cfa-020361	Canis familiaris	99.54	0.00e+00	2234.00
IUUC-Cpo-022320	Cavia porcellus	99.17	0.00e+00	2218.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	43.84	1.00e-91	330.00
IUUC-Csa-024050	Chlorocebus sabaeus	99.63	0.00e+00	2224.00
IUUC-Cho-024434	Choloepus hoffmanni	90.55	0.00e+00	1437.00
IUUC-Cin-025689	Ciona intestinalis	54.45	0.00e+00	1213.00
IUUC-Csv-025963	Ciona savignyi	52.41	0.00e+00	1165.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	33.24	9.00e-151	528.00
IUUC-Cne-026968	Cryptococcus neoformans	36.57	0.00e+00	627.00
IUUC-Cme-027103	Cyanidioschyzon merolae	35.69	2.00e-115	410.00
IUUC-Dre-028510	Danio rerio	93.38	0.00e+00	2131.00
IUUC-Dno-029696	Dasypus novemcinctus	98.46	0.00e+00	2239.00
IUUC-Dor-030611	Dipodomys ordii	82.93	0.00e+00	986.00
IUUC-Dse-031433	Dothistroma septosporum	34.74	1.00e-146	514.00
IUUC-Dme-031583	Drosophila melanogaster	48.58	0.00e+00	1043.00
IUUC-Ete-033191	Echinops telfairi	96.40	0.00e+00	2207.00
IUUC-Eca-034122	Equus caballus	99.17	0.00e+00	2229.00
IUUC-Eeu-035292	Erinaceus europaeus	76.47	0.00e+00	688.00
IUUC-Fca-036377	Felis catus	99.09	0.00e+00	2245.00
IUUC-Fal-036964	Ficedula albicollis	96.97	0.00e+00	2158.00
IUUC-Fox-037695	Fusarium oxysporum	33.30	1.00e-158	553.00
IUUC-Fso-038084	Fusarium solani	33.36	3.00e-158	552.00
IUUC-Gmo-038644	Gadus morhua	92.87	0.00e+00	2124.00
IUUC-Ggr-040029	Gaeumannomyces graminis	33.67	3.00e-157	549.00
IUUC-Gga-040944	Gallus gallus	97.10	0.00e+00	2191.00
IUUC-Gac-041740	Gasterosteus aculeatus	93.52	0.00e+00	2135.00
IUUC-Gma-043300	Glycine max	36.30	4.00e-168	585.00
IUUC-Hsa-046278	Homo sapiens	99.63	0.00e+00	2224.00
IUUC-Hvu-047749	Hordeum vulgare	37.01	5.00e-142	498.00
IUUC-Itr-047904	Ictidomys tridecemlineatus	99.36	0.00e+00	1906.00
IUUC-Kpa-049121	Komagataella pastoris	31.03	3.00e-126	446.00
IUUC-Lch-049847	Latimeria chalumnae	96.02	0.00e+00	2179.00
IUUC-Lpe-051505	Leersia perrieri	35.78	8.00e-143	501.00
IUUC-Loc-052234	Lepisosteus oculatus	93.34	0.00e+00	1420.00
IUUC-Lma-053169	Leptosphaeria maculans	36.66	2.00e-167	583.00
IUUC-Laf-053566	Loxodonta africana	99.44	0.00e+00	2217.00
IUUC-Mcc-055549	Macaca mulatta	99.63	0.00e+00	2215.00
IUUC-Meu-056887	Macropus eugenii	88.25	0.00e+00	1281.00
IUUC-Mor-057149	Magnaporthe oryzae	34.60	1.00e-158	553.00
IUUC-Mpo-057536	Magnaporthe poae	33.51	9.00e-158	551.00
IUUC-Mtr-058583	Medicago truncatula	37.37	7.00e-164	571.00
IUUC-Mla-058899	Melampsora laricipopulina	36.89	3.00e-171	595.00
IUUC-Mga-060148	Meleagris gallopavo	96.50	0.00e+00	2208.00
IUUC-Mvi-060207	Microbotryum violaceum	37.62	0.00e+00	633.00
IUUC-Mmr-060946	Microcebus murinus	99.07	0.00e+00	2215.00
IUUC-Mdo-062079	Monodelphis domestica	90.57	0.00e+00	1976.00
IUUC-Mmu-063678	Mus musculus	98.71	0.00e+00	2208.00
IUUC-Mac-065416	Musa acuminata	36.98	9.00e-157	547.00
IUUC-Mpu-066744	Mustela putorius furo	99.43	0.00e+00	2168.00
IUUC-Mlu-067949	Myotis lucifugus	98.02	0.00e+00	2241.00
IUUC-Nfi-068342	Neosartorya fischeri	35.28	1.00e-161	564.00
IUUC-Ncr-068818	Neurospora crassa	34.42	2.00e-162	566.00
IUUC-Nle-070064	Nomascus leucogenys	99.72	0.00e+00	2225.00
IUUC-Opr-071001	Ochotona princeps	96.49	0.00e+00	1840.00
IUUC-Ont-072095	Oreochromis niloticus	93.01	0.00e+00	2127.00
IUUC-Oan-073483	Ornithorhynchus anatinus	97.73	0.00e+00	2139.00
IUUC-Ocu-073967	Oryctolagus cuniculus	97.31	0.00e+00	2151.00
IUUC-Oba-075811	Oryza barthii	33.79	5.00e-141	495.00
IUUC-Obr-076857	Oryza brachyantha	35.89	3.00e-153	536.00
IUUC-Ogl-077038	Oryza glaberrima	35.70	1.00e-150	528.00
IUUC-Ogu-078265	Oryza glumaepatula	34.10	2.00e-136	480.00
IUUC-Oin-079513	Oryza indica	34.86	6.00e-142	498.00
IUUC-Olo-081067	Oryza longistaminata	33.73	3.00e-139	489.00
IUUC-Ome-081879	Oryza meridionalis	36.19	5.00e-151	528.00
IUUC-Oni-082409	Oryza nivara	33.46	2.00e-140	493.00
IUUC-Opu-083199	Oryza punctata	35.26	2.00e-147	516.00
IUUC-Oru-085109	Oryza rufipogon	35.58	7.00e-146	511.00
IUUC-Osa-085418	Oryza sativa	37.24	7.00e-131	461.00
IUUC-Ola-086640	Oryzias latipes	92.15	0.00e+00	2123.00
IUUC-Olu-087874	Ostreococcus lucimarinus	33.73	1.00e-143	504.00
IUUC-Oga-089059	Otolemur garnettii	92.05	0.00e+00	2073.00
IUUC-Oar-089710	Ovis aries	98.11	0.00e+00	2251.00
IUUC-Ptr-091334	Pan troglodytes	100.00	0.00e+00	2295.00
IUUC-Pan-091717	Papio anubis	100.00	0.00e+00	2153.00
IUUC-Psi-093933	Pelodiscus sinensis	96.31	0.00e+00	2198.00
IUUC-Pma-094648	Petromyzon marinus	82.23	0.00e+00	1726.00
IUUC-Pno-095020	Phaeosphaeria nodorum	35.16	8.00e-150	524.00
IUUC-Ppa-096020	Physcomitrella patens	34.71	7.00e-162	565.00
IUUC-Pfo-096181	Poecilia formosa	92.92	0.00e+00	2127.00
IUUC-Pab-098231	Pongo abelii	97.39	0.00e+00	2221.00
IUUC-Pop-099680	Populus trichocarpa	37.36	6.00e-160	558.00
IUUC-Pca-100543	Procavia capensis	81.07	0.00e+00	1045.00
IUUC-Ppe-101523	Prunus persica	35.95	1.00e-154	540.00
IUUC-Pva-102472	Pteropus vampyrus	97.48	0.00e+00	2217.00
IUUC-Pgr-103463	Puccinia graminis	36.08	1.00e-170	594.00
IUUC-Ptt-103716	Puccinia triticina	37.75	9.00e-168	584.00
IUUC-Pte-104360	Pyrenophora teres	36.13	3.00e-151	529.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	35.75	2.00e-149	523.00
IUUC-Rno-105816	Rattus norvegicus	99.07	0.00e+00	2214.00
IUUC-Sce-106230	Saccharomyces cerevisiae	30.02	5.00e-123	436.00
IUUC-Sha-107439	Sarcophilus harrisii	98.05	0.00e+00	2187.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	33.09	5.00e-139	488.00
IUUC-Spo-108019	Schizosaccharomyces pombe	34.45	5.00e-144	505.00
IUUC-Smo-109308	Selaginella moellendorffii	35.48	1.00e-152	533.00
IUUC-Sit-110367	Setaria italica	36.25	7.00e-158	551.00
IUUC-Sly-111337	Solanum lycopersicum	37.88	3.00e-163	569.00
IUUC-Stu-112387	Solanum tuberosum	36.66	2.00e-165	576.00
IUUC-Sar-113685	Sorex araneus	96.76	0.00e+00	2211.00
IUUC-Sbi-114037	Sorghum bicolor	36.68	2.00e-158	553.00
IUUC-Sre-115156	Sporisorium reilianum	36.68	0.00e+00	632.00
IUUC-Ssc-116297	Sus scrofa	99.07	0.00e+00	2217.00
IUUC-Tgu-116767	Taeniopygia guttata	96.58	0.00e+00	2201.00
IUUC-Tru-118208	Takifugu rubripes	93.06	0.00e+00	2098.00
IUUC-Tsy-119277	Tarsius syrichta	89.81	0.00e+00	738.00
IUUC-Tni-119890	Tetraodon nigroviridis	93.24	0.00e+00	2103.00
IUUC-Tca-121696	Theobroma cacao	37.30	3.00e-155	542.00
IUUC-Tre-122169	Trichoderma reesei	33.36	9.00e-153	534.00
IUUC-Tvi-122600	Trichoderma virens	34.15	4.00e-160	558.00
IUUC-Tae-125264	Triticum aestivum	35.35	2.00e-156	547.00
IUUC-Tur-126287	Triticum urartu	35.22	3.00e-149	523.00
IUUC-Tme-127045	Tuber melanosporum	35.35	2.00e-166	580.00
IUUC-Tbe-127696	Tupaia belangeri	88.60	6.00e-161	561.00
IUUC-Ttr-129161	Tursiops truncatus	98.29	0.00e+00	2249.00
IUUC-Uma-129535	Ustilago maydis	36.84	0.00e+00	642.00
IUUC-Vda-129708	Verticillium dahliae	32.81	2.00e-158	553.00
IUUC-Vvi-131048	Vitis vinifera	35.79	7.00e-159	555.00
IUUC-Xtr-132073	Xenopus tropicalis	92.31	0.00e+00	2076.00
IUUC-Xma-133949	Xiphophorus maculatus	92.64	0.00e+00	2118.00
IUUC-Yli-134527	Yarrowia lipolytica	32.80	5.00e-139	489.00
IUUC-Zma-135550	Zea mays	34.70	3.00e-148	519.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence