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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-104960
Ensembl Protein ID ENSRNOP00000010680.2
UniProt Accession G3V715; G3V715_RAT
Genbank Protein ID EDL97882.1
Protein Name Non-specific serine/threonine protein kinase
Genbank Nucleotide ID AABR07049501
Gene Name Prkaa2; rCG_53426
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000007706.3 ENSRNOT00000010680.3 ENSRNOP00000010680.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACmiRNAMapRAID2
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 48.07 2.00e-124 442.00 IUUC-Ath-007014
UBD/Alpha-Helix/UBA 41.29 2.00e-106 381.00 IUUC-Spo-108202
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MAEKQKHDGR VKIGHYVLGD TLGVGTFGKV KIGEHQLTGH KVAVKILNRQ KIRSLDVVGK 60
IKREIQNLKL FRHPHIIKLY QVISTPTDFF MVMEYVSGGE LFDYICKHGR VEEVEARRLF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-104960|UBD,UBA|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCGAACATG GCTGAGAAGC AGAAGCACGA CGGGCGTGTG AAGATCGGAC ACTACGTGCT 60
GGGGGACACC CTGGGCGTCG GCACCTTCGG CAAAGTGAAG AGTGAGTGCA GCGGCGCGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-104960|UBD,UBA|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF16579--AdenylateSensor
PF00069--Pkinase
SMART

SM00220--S_TKc
Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0016607--C:nuclear speck
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0035690--P:cellular response to drug
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0042593--P:glucose homeostasis
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0042752--P:regulation of circadian rhythm
GO:0010468--P:regulation of gene expression
GO:0016241--P:regulation of macroautophagy
GO:0014850--P:response to muscle activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000713 Aegilops tauschii 47.01 5.00e-122 431.00
IUUC-Aml-001907 Ailuropoda melanoleuca 75.41 0.00e+00 793.00
IUUC-Atr-002770 Amborella trichopoda 47.77 6.00e-125 441.00
IUUC-Apl-003395 Anas platyrhynchos 93.30 0.00e+00 1021.00
IUUC-Aca-004480 Anolis carolinensis 93.16 0.00e+00 1023.00
IUUC-Aly-006289 Arabidopsis lyrata 47.96 1.00e-125 443.00
IUUC-Ath-007014 Arabidopsis thaliana 48.07 7.00e-126 444.00
IUUC-Ago-007957 Ashbya gossypii 42.62 7.00e-115 407.00
IUUC-Acl-008103 Aspergillus clavatus 60.07 4.00e-101 362.00
IUUC-Afl-008555 Aspergillus flavus 59.71 7.00e-102 365.00
IUUC-Afu-008949 Aspergillus fumigatus 47.78 2.00e-101 363.00
IUUC-Ani-009408 Aspergillus nidulans 62.17 9.00e-102 364.00
IUUC-Ang-009551 Aspergillus niger 60.07 2.00e-101 363.00
IUUC-Aor-010176 Aspergillus oryzae 59.71 7.00e-102 365.00
IUUC-Ate-010287 Aspergillus terreus 60.07 5.00e-101 362.00
IUUC-Ame-011019 Astyanax mexicanus 86.10 0.00e+00 1013.00
IUUC-Bgr-012045 Blumeria graminis 61.80 4.00e-102 365.00
IUUC-Bta-012786 Bos taurus 75.41 0.00e+00 793.00
IUUC-Bci-013774 Botrytis cinerea 46.84 4.00e-104 372.00
IUUC-Bdi-014319 Brachypodium distachyon 47.14 6.00e-125 441.00
IUUC-Bol-016242 Brassica oleracea 48.35 3.00e-128 451.00
IUUC-Bra-016750 Brassica rapa 48.25 2.00e-128 452.00
IUUC-Cel-018518 Caenorhabditis elegans 58.19 0.00e+00 629.00
IUUC-Cja-019386 Callithrix jacchus 98.01 0.00e+00 1097.00
IUUC-Cfa-020177 Canis familiaris 74.05 0.00e+00 761.00
IUUC-Cpo-021805 Cavia porcellus 98.37 0.00e+00 1100.00
IUUC-Cre-022915 Chlamydomonas reinhardtii 54.83 1.00e-96 346.00
IUUC-Csa-024267 Chlorocebus sabaeus 98.19 0.00e+00 1085.00
IUUC-Cho-024859 Choloepus hoffmanni 71.32 0.00e+00 748.00
IUUC-Cin-025550 Ciona intestinalis 62.52 0.00e+00 681.00
IUUC-Csv-026139 Ciona savignyi 61.20 0.00e+00 677.00
IUUC-Cne-027044 Cryptococcus neoformans 50.77 2.00e-108 387.00
IUUC-Cme-027289 Cyanidioschyzon merolae 45.57 6.00e-111 394.00
IUUC-Dre-027749 Danio rerio 70.02 0.00e+00 791.00
IUUC-Dno-030006 Dasypus novemcinctus 74.32 0.00e+00 793.00
IUUC-Dor-030578 Dipodomys ordii 98.01 0.00e+00 1099.00
IUUC-Dse-031507 Dothistroma septosporum 63.06 4.00e-105 375.00
IUUC-Dme-031704 Drosophila melanogaster 60.24 0.00e+00 664.00
IUUC-Ete-033055 Echinops telfairi 72.63 0.00e+00 809.00
IUUC-Eca-034016 Equus caballus 97.89 0.00e+00 1033.00
IUUC-Fca-035754 Felis catus 72.66 0.00e+00 787.00
IUUC-Fal-037363 Ficedula albicollis 74.23 0.00e+00 785.00
IUUC-Fox-038073 Fusarium oxysporum 51.92 1.00e-105 377.00
IUUC-Fso-038236 Fusarium solani 51.24 7.00e-102 364.00
IUUC-Gmo-039633 Gadus morhua 70.33 0.00e+00 821.00
IUUC-Ggr-039987 Gaeumannomyces graminis 49.04 5.00e-102 365.00
IUUC-Gga-040546 Gallus gallus 91.86 0.00e+00 1057.00
IUUC-Gac-041822 Gasterosteus aculeatus 83.63 0.00e+00 949.00
IUUC-Gma-042712 Glycine max 47.07 4.00e-125 441.00
IUUC-Ggo-045303 Gorilla gorilla 98.37 0.00e+00 1101.00
IUUC-Hsa-045746 Homo sapiens 98.37 0.00e+00 1101.00
IUUC-Hvu-047406 Hordeum vulgare 46.94 6.00e-125 441.00
IUUC-Itr-048134 Ictidomys tridecemlineatus 98.19 0.00e+00 1098.00
IUUC-Kpa-049190 Komagataella pastoris 45.06 1.00e-122 433.00
IUUC-Lch-049623 Latimeria chalumnae 73.05 0.00e+00 786.00
IUUC-Lpe-051392 Leersia perrieri 46.73 7.00e-125 440.00
IUUC-Loc-052928 Lepisosteus oculatus 89.87 0.00e+00 1033.00
IUUC-Lma-053054 Leptosphaeria maculans 63.30 1.00e-106 380.00
IUUC-Laf-053459 Loxodonta africana 97.10 0.00e+00 1090.00
IUUC-Mcc-055862 Macaca mulatta 98.37 0.00e+00 1101.00
IUUC-Mor-057170 Magnaporthe oryzae 57.39 4.00e-100 358.00
IUUC-Mpo-057302 Magnaporthe poae 49.18 6.00e-102 365.00
IUUC-Mtr-058309 Medicago truncatula 48.12 7.00e-124 437.00
IUUC-Mla-059058 Melampsora laricipopulina 43.09 4.00e-104 372.00
IUUC-Mga-059206 Meleagris gallopavo 91.36 0.00e+00 996.00
IUUC-Mvi-060337 Microbotryum violaceum 41.84 2.00e-107 383.00
IUUC-Mmr-061619 Microcebus murinus 97.83 0.00e+00 1087.00
IUUC-Mdo-062160 Monodelphis domestica 92.75 0.00e+00 1063.00
IUUC-Mmu-063406 Mus musculus 98.37 0.00e+00 1096.00
IUUC-Mac-064518 Musa acuminata 45.54 1.00e-121 430.00
IUUC-Mpu-066326 Mustela putorius furo 97.89 0.00e+00 1032.00
IUUC-Mlu-067968 Myotis lucifugus 96.02 0.00e+00 995.00
IUUC-Nfi-068493 Neosartorya fischeri 60.07 2.00e-101 363.00
IUUC-Ncr-068665 Neurospora crassa 40.98 3.00e-106 379.00
IUUC-Nle-070158 Nomascus leucogenys 98.19 0.00e+00 1099.00
IUUC-Opr-070272 Ochotona princeps 72.49 0.00e+00 785.00
IUUC-Ont-071395 Oreochromis niloticus 85.84 0.00e+00 993.00
IUUC-Oan-073322 Ornithorhynchus anatinus 68.43 0.00e+00 747.00
IUUC-Ocu-074188 Oryctolagus cuniculus 73.06 0.00e+00 786.00
IUUC-Oba-075436 Oryza barthii 47.24 1.00e-126 446.00
IUUC-Obr-076507 Oryza brachyantha 47.57 2.00e-126 446.00
IUUC-Ogl-077718 Oryza glaberrima 50.11 1.00e-123 436.00
IUUC-Ogu-078349 Oryza glumaepatula 46.91 7.00e-127 447.00
IUUC-Oin-079889 Oryza indica 45.81 4.00e-124 438.00
IUUC-Olo-080521 Oryza longistaminata 47.24 2.00e-126 446.00
IUUC-Ome-081630 Oryza meridionalis 47.03 4.00e-126 444.00
IUUC-Oni-082211 Oryza nivara 47.24 6.00e-127 447.00
IUUC-Opu-083617 Oryza punctata 46.94 3.00e-125 442.00
IUUC-Oru-084252 Oryza rufipogon 47.24 2.00e-126 446.00
IUUC-Osa-085548 Oryza sativa 47.24 2.00e-126 446.00
IUUC-Ola-087169 Oryzias latipes 84.23 0.00e+00 969.00
IUUC-Olu-087861 Ostreococcus lucimarinus 49.18 4.00e-116 411.00
IUUC-Oga-088003 Otolemur garnettii 74.50 0.00e+00 795.00
IUUC-Oar-089933 Ovis aries 75.41 0.00e+00 793.00
IUUC-Ptr-090741 Pan troglodytes 98.37 0.00e+00 1101.00
IUUC-Pan-092526 Papio anubis 74.68 0.00e+00 796.00
IUUC-Psi-094034 Pelodiscus sinensis 74.01 0.00e+00 784.00
IUUC-Pno-095030 Phaeosphaeria nodorum 63.30 8.00e-105 373.00
IUUC-Ppa-095615 Physcomitrella patens 45.28 7.00e-124 437.00
IUUC-Pfo-096295 Poecilia formosa 85.13 0.00e+00 980.00
IUUC-Pab-098023 Pongo abelii 98.37 0.00e+00 1101.00
IUUC-Pop-100042 Populus trichocarpa 47.98 3.00e-128 452.00
IUUC-Pca-101104 Procavia capensis 78.62 1.00e-174 605.00
IUUC-Ppe-101642 Prunus persica 48.95 2.00e-125 442.00
IUUC-Pva-102470 Pteropus vampyrus 97.10 0.00e+00 1082.00
IUUC-Pgr-103406 Puccinia graminis 61.36 8.00e-92 331.00
IUUC-Ptt-103713 Puccinia triticina 37.85 9.00e-79 288.00
IUUC-Pte-104259 Pyrenophora teres 62.55 2.00e-105 377.00
IUUC-Pyt-104752 Pyrenophora triticirepentis 62.92 5.00e-106 379.00
IUUC-Sce-106290 Saccharomyces cerevisiae 42.46 1.00e-115 410.00
IUUC-Sha-107603 Sarcophilus harrisii 74.32 0.00e+00 791.00
IUUC-Sja-107772 Schizosaccharomyces japonicus 40.53 4.00e-110 392.00
IUUC-Spo-108202 Schizosaccharomyces pombe 41.29 5.00e-107 381.00
IUUC-Ssl-108535 Sclerotinia sclerotiorum 46.34 3.00e-103 369.00
IUUC-Smo-109309 Selaginella moellendorffii 45.44 6.00e-122 431.00
IUUC-Sit-109745 Setaria italica 48.18 6.00e-127 447.00
IUUC-Sly-110890 Solanum lycopersicum 48.07 2.00e-126 445.00
IUUC-Stu-112144 Solanum tuberosum 46.23 5.00e-119 421.00
IUUC-Sar-113521 Sorex araneus 64.75 0.00e+00 635.00
IUUC-Sbi-114764 Sorghum bicolor 47.99 7.00e-128 450.00
IUUC-Sre-115141 Sporisorium reilianum 66.91 9.00e-115 407.00
IUUC-Ssc-115732 Sus scrofa 74.19 0.00e+00 758.00
IUUC-Tgu-117190 Taeniopygia guttata 74.41 0.00e+00 783.00
IUUC-Tru-118735 Takifugu rubripes 84.41 0.00e+00 979.00
IUUC-Tsy-119503 Tarsius syrichta 94.62 0.00e+00 978.00
IUUC-Tni-119880 Tetraodon nigroviridis 84.44 0.00e+00 978.00
IUUC-Tca-121386 Theobroma cacao 47.46 4.00e-127 448.00
IUUC-Tre-122070 Trichoderma reesei 40.90 4.00e-103 369.00
IUUC-Tvi-122305 Trichoderma virens 47.69 6.00e-102 365.00
IUUC-Tae-123515 Triticum aestivum 47.54 2.00e-126 445.00
IUUC-Tur-126416 Triticum urartu 46.85 2.00e-123 436.00
IUUC-Tme-127174 Tuber melanosporum 53.15 4.00e-66 245.00
IUUC-Tbe-127791 Tupaia belangeri 85.22 2.00e-112 399.00
IUUC-Ttr-129224 Tursiops truncatus 72.66 0.00e+00 784.00
IUUC-Uma-129372 Ustilago maydis 66.91 4.00e-114 405.00
IUUC-Vda-129819 Verticillium dahliae 54.04 9.00e-87 314.00
IUUC-Vpa-130220 Vicugna pacos 97.69 0.00e+00 1027.00
IUUC-Vvi-131649 Vitis vinifera 47.97 1.00e-125 443.00
IUUC-Xtr-132954 Xenopus tropicalis 92.22 0.00e+00 1063.00
IUUC-Xma-134119 Xiphophorus maculatus 84.95 0.00e+00 978.00
IUUC-Yli-134422 Yarrowia lipolytica 45.58 3.00e-119 422.00
IUUC-Zma-135621 Zea mays 62.31 1.00e-120 427.00
Created Date 25-Jun-2017

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