iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068245

Ensembl Protein ID

CADNFIAP00005046

UniProt Accession

A1DNB7; A1DNB7_NEOFI

Genbank Protein ID

EAW16288.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

DS027698

Gene Name

NFIA_056370

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00005174	CADNFIAT00005174	CADNFIAP00005046

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	9.50e-60	202.0	19	547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagg............lGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaeal 81
           YDRQ+rlw + +q++l++++vllv+ +g             G+E+lKnLvl G+g +t+vD + v+  +l+ +F+++ae+ gks+Ae +++ l
   Q: 19   YDRQLRLWAASGQQALEESRVLLVNSDGswgnqgtgvsgvAGVETLKNLVLPGIGGFTIVDPAVVTEPDLGVNFFLEAESLGKSRAEETCRLL 111
           ************************8765444444333333589************************************************** PP
   S: 82   kelnpdvnveaheesiteleeeiv.FfkkfdvVvlaldnrearrkvnrlclna...rvpliesgtlGllGqvrviik.gltecyscsd....d 165
           +elnpdv++++ ++si e  ++++ F+ ++ +V++    ++ r ++++lc +a   ++p +   + G+++  +  ++ ++++ + ++d    +
   Q: 112  RELNPDVEGSFRSKSIAEVLQQEPdFLAQHRLVLISGP-VK-RSTLDTLCNAAkalNIPVLYLHSVGFYSVFSLQLPaEFPIVETHPDpeatQ 202
           **********************99*********88654.43.44799999877999****************999994577777777799999 PP
   S: 166  ppqktiPfctlketpn..........aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavka 244
           ++++ +P+++l+   +           ++ +++++ l+ ++le+++++++++ +++++ek+e+++ v++++++      een++ea+++++k+
   Q: 203  DLRLLNPWPELAAAGAsisnldsmddHQHGHVPYVLLLLHYLEKWKQAHDGNVPSNYKEKSEFREFVRASARTnnaeGGEENYDEAVAAVLKS 295
           ************99666667777777*******************************************999966665699************ PP
   S: 245  fakttins.ikqllksfecdivtkskspfwv.............................................................. 274
           +++++  s i++++++++c ++ +++++fw+                                                              
   Q: 296  LNPFSLRSsIREIFEMDQCRNLKQDSAEFWLiaaavhefyqkhkvlplpgslpdmkaqsadyvslqniykskarkdveeitatvrrleaqlgp 388
           ********************************************************************************************* PP
   S: 275  ...........sfcsnaealqvp............ekvekdeevvkasap...lylllralerfekkkgrkpgelsfekddds.avdlvtaaa 340
                       fc+na+ ++v             ++ +  + ++++s++   + ++  +l+   ++ +++    ++  dd+s     ++++ 
   Q: 389  rravipekdieVFCKNAAHIKVIhgrdipringdaQTLKAIMDNLSSSEAlvpIFIACHILDDIVTDIQEYN-IADVSLDDKSlWNTHIQQVI 480
           *********************444444555555558888889999988889998888888888877777775.56667777776666677777 PP
   S: 341  nlraeslgiep.kldd...dlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           +  a++ ++    + +   ++++e+ +++ ++++ ++a  gGl+aqE++Kv++ +++pl+n+ +fd+
   Q: 481  SKLASDPAVIDeRAREkilEATQELRRTEGGELHNISALTGGLVAQEALKVITRQYVPLDNTCIFDG 547
           77777777776555551224678999***************************************97 PP

Organism

Neosartorya fischeri

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MTDTFPAALV GPSSKERKYD RQLRLWAASG QQALEESRVL LVNSDGSWGN QGTGVSGVAG 60
VETLKNLVLP GIGGFTIVDP AVVTEPDLGV NFFLEAESLG KSRAEETCRL LRELNPDVEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGATA CTTTCCCTGC TGCCCTGGTA GGGCCATCTT CGAAAGAGAG GAAGTATGAT 60
CGCCAGCTAC GTTTGTGGGC TGCGAGCGGG CAGCAAGCAC TGGAAGAGTC TCGTGTTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

nfi:NFIA_056370

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	32.80	2.00e-74	271.00
IUUC-Aml-002333	Ailuropoda melanoleuca	34.76	2.00e-87	314.00
IUUC-Atr-002644	Amborella trichopoda	32.36	2.00e-67	248.00
IUUC-Apl-003446	Anas platyrhynchos	33.70	2.00e-78	284.00
IUUC-Aca-004450	Anolis carolinensis	33.63	3.00e-85	307.00
IUUC-Aly-006187	Arabidopsis lyrata	34.12	5.00e-81	293.00
IUUC-Ath-006692	Arabidopsis thaliana	32.48	3.00e-79	287.00
IUUC-Ago-007900	Ashbya gossypii	24.55	3.00e-31	127.00
IUUC-Acl-008333	Aspergillus clavatus	83.33	0.00e+00	944.00
IUUC-Afl-008529	Aspergillus flavus	77.42	0.00e+00	868.00
IUUC-Afu-009071	Aspergillus fumigatus	95.69	0.00e+00	1074.00
IUUC-Ani-009443	Aspergillus nidulans	73.97	0.00e+00	812.00
IUUC-Ang-009669	Aspergillus niger	76.73	0.00e+00	894.00
IUUC-Aor-009914	Aspergillus oryzae	76.91	0.00e+00	864.00
IUUC-Ate-010450	Aspergillus terreus	75.09	0.00e+00	859.00
IUUC-Ame-011183	Astyanax mexicanus	34.65	9.00e-92	328.00
IUUC-Bgr-012111	Blumeria graminis	45.18	3.00e-122	430.00
IUUC-Bta-012583	Bos taurus	34.11	7.00e-88	316.00
IUUC-Bci-013892	Botrytis cinerea	47.57	1.00e-138	484.00
IUUC-Bdi-014592	Brachypodium distachyon	33.09	1.00e-73	268.00
IUUC-Bol-016401	Brassica oleracea	32.66	3.00e-79	287.00
IUUC-Bra-017506	Brassica rapa	32.36	3.00e-75	274.00
IUUC-Cel-018456	Caenorhabditis elegans	30.70	4.00e-59	220.00
IUUC-Cja-020007	Callithrix jacchus	34.05	8.00e-88	315.00
IUUC-Cfa-020324	Canis familiaris	33.87	1.00e-87	315.00
IUUC-Cpo-022248	Cavia porcellus	32.23	2.00e-48	184.00
IUUC-Csa-023149	Chlorocebus sabaeus	31.45	2.00e-64	238.00
IUUC-Cho-024537	Choloepus hoffmanni	27.64	8.00e-49	186.00
IUUC-Cin-025763	Ciona intestinalis	34.67	8.00e-86	309.00
IUUC-Csv-026113	Ciona savignyi	33.27	3.00e-86	310.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	43.71	3.00e-124	437.00
IUUC-Cne-026884	Cryptococcus neoformans	30.51	3.00e-66	244.00
IUUC-Dre-028140	Danio rerio	34.35	1.00e-88	318.00
IUUC-Dno-030033	Dasypus novemcinctus	38.01	1.00e-78	285.00
IUUC-Dor-030513	Dipodomys ordii	49.57	4.00e-24	103.00
IUUC-Dse-031536	Dothistroma septosporum	45.38	5.00e-137	479.00
IUUC-Dme-031683	Drosophila melanogaster	35.19	8.00e-79	286.00
IUUC-Ete-032420	Echinops telfairi	31.01	6.00e-67	246.00
IUUC-Eca-033992	Equus caballus	30.92	1.00e-61	228.00
IUUC-Eeu-034713	Erinaceus europaeus	51.85	5.00e-26	110.00
IUUC-Fca-036548	Felis catus	33.51	6.00e-87	313.00
IUUC-Fal-037600	Ficedula albicollis	31.88	2.00e-74	271.00
IUUC-Fox-038037	Fusarium oxysporum	46.38	4.00e-132	462.00
IUUC-Fso-038387	Fusarium solani	44.83	1.00e-132	464.00
IUUC-Gmo-038562	Gadus morhua	34.51	1.00e-89	321.00
IUUC-Ggr-040005	Gaeumannomyces graminis	46.48	2.00e-138	484.00
IUUC-Gga-041129	Gallus gallus	34.41	5.00e-83	300.00
IUUC-Gac-042558	Gasterosteus aculeatus	34.05	1.00e-86	312.00
IUUC-Gma-043610	Glycine max	33.15	2.00e-72	264.00
IUUC-Ggo-045611	Gorilla gorilla	34.22	1.00e-87	315.00
IUUC-Hsa-046563	Homo sapiens	34.22	7.00e-89	319.00
IUUC-Hvu-047790	Hordeum vulgare	29.17	5.00e-43	166.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	34.41	4.00e-88	317.00
IUUC-Kpa-049309	Komagataella pastoris	33.15	2.00e-73	268.00
IUUC-Lch-050038	Latimeria chalumnae	35.20	3.00e-81	294.00
IUUC-Lpe-051535	Leersia perrieri	30.27	4.00e-56	210.00
IUUC-Loc-051917	Lepisosteus oculatus	32.93	2.00e-78	285.00
IUUC-Lma-053112	Leptosphaeria maculans	50.17	4.00e-159	553.00
IUUC-Laf-053690	Loxodonta africana	34.05	1.00e-89	322.00
IUUC-Mcc-055117	Macaca mulatta	33.27	6.00e-84	303.00
IUUC-Meu-056761	Macropus eugenii	26.74	6.00e-56	209.00
IUUC-Mor-057230	Magnaporthe oryzae	47.38	2.00e-142	497.00
IUUC-Mpo-057514	Magnaporthe poae	46.41	1.00e-130	458.00
IUUC-Mtr-058551	Medicago truncatula	32.27	1.00e-66	245.00
IUUC-Mla-059183	Melampsora laricipopulina	33.04	7.00e-82	296.00
IUUC-Mga-060144	Meleagris gallopavo	33.39	1.00e-79	288.00
IUUC-Mvi-060221	Microbotryum violaceum	38.39	1.00e-68	252.00
IUUC-Mmr-061325	Microcebus murinus	33.33	5.00e-83	300.00
IUUC-Mdo-062532	Monodelphis domestica	34.05	1.00e-87	315.00
IUUC-Mmu-063956	Mus musculus	34.23	5.00e-89	320.00
IUUC-Mac-064521	Musa acuminata	32.44	1.00e-73	268.00
IUUC-Mpu-066716	Mustela putorius furo	33.59	2.00e-78	284.00
IUUC-Mlu-067459	Myotis lucifugus	34.36	2.00e-90	324.00
IUUC-Ncr-068910	Neurospora crassa	48.35	4.00e-147	513.00
IUUC-Nle-070034	Nomascus leucogenys	32.66	7.00e-80	289.00
IUUC-Opr-070552	Ochotona princeps	34.87	2.00e-65	241.00
IUUC-Ont-071426	Oreochromis niloticus	35.06	9.00e-92	328.00
IUUC-Oan-073389	Ornithorhynchus anatinus	31.88	1.00e-57	215.00
IUUC-Ocu-074911	Oryctolagus cuniculus	34.11	8.00e-88	315.00
IUUC-Oba-075437	Oryza barthii	32.06	8.00e-64	236.00
IUUC-Obr-076684	Oryza brachyantha	31.02	4.00e-58	217.00
IUUC-Ogl-077170	Oryza glaberrima	32.06	8.00e-64	236.00
IUUC-Ogu-078844	Oryza glumaepatula	31.82	7.00e-56	209.00
IUUC-Oin-079105	Oryza indica	32.25	3.00e-63	234.00
IUUC-Olo-080943	Oryza longistaminata	29.31	1.00e-50	192.00
IUUC-Oni-082891	Oryza nivara	29.89	3.00e-57	214.00
IUUC-Opu-083457	Oryza punctata	32.24	4.00e-63	233.00
IUUC-Oru-084960	Oryza rufipogon	29.27	6.00e-51	193.00
IUUC-Osa-085358	Oryza sativa	32.25	6.00e-63	233.00
IUUC-Ola-086420	Oryzias latipes	32.47	1.00e-54	205.00
IUUC-Olu-087625	Ostreococcus lucimarinus	25.22	4.00e-42	164.00
IUUC-Oga-088810	Otolemur garnettii	34.05	6.00e-89	319.00
IUUC-Oar-089196	Ovis aries	33.87	9.00e-87	312.00
IUUC-Ptr-090617	Pan troglodytes	34.05	3.00e-88	317.00
IUUC-Pan-092761	Papio anubis	34.41	2.00e-89	320.00
IUUC-Psi-093191	Pelodiscus sinensis	33.09	8.00e-80	289.00
IUUC-Pma-094380	Petromyzon marinus	37.39	2.00e-77	281.00
IUUC-Pno-095084	Phaeosphaeria nodorum	47.13	6.00e-138	483.00
IUUC-Ppa-095875	Physcomitrella patens	30.94	2.00e-69	254.00
IUUC-Pfo-096467	Poecilia formosa	35.19	3.00e-91	327.00
IUUC-Pab-098255	Pongo abelii	36.51	3.00e-79	287.00
IUUC-Pop-099871	Populus trichocarpa	33.03	3.00e-75	274.00
IUUC-Pca-100807	Procavia capensis	36.41	3.00e-28	117.00
IUUC-Ppe-101280	Prunus persica	33.03	2.00e-78	285.00
IUUC-Pva-102333	Pteropus vampyrus	32.68	3.00e-78	284.00
IUUC-Pgr-103401	Puccinia graminis	30.55	8.00e-67	246.00
IUUC-Ptt-103889	Puccinia triticina	31.11	2.00e-68	251.00
IUUC-Pte-104355	Pyrenophora teres	50.87	3.00e-159	553.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	50.70	2.00e-158	550.00
IUUC-Rno-105810	Rattus norvegicus	33.87	1.00e-86	312.00
IUUC-Sha-106770	Sarcophilus harrisii	39.79	3.00e-52	196.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	31.68	1.00e-72	265.00
IUUC-Spo-108276	Schizosaccharomyces pombe	33.58	4.00e-78	283.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	48.93	1.00e-140	491.00
IUUC-Smo-109296	Selaginella moellendorffii	32.43	1.00e-74	271.00
IUUC-Sit-110157	Setaria italica	32.97	4.00e-75	273.00
IUUC-Sly-111105	Solanum lycopersicum	32.44	4.00e-76	277.00
IUUC-Stu-112469	Solanum tuberosum	32.44	9.00e-77	279.00
IUUC-Sar-113083	Sorex araneus	25.00	4.00e-45	174.00
IUUC-Sbi-113813	Sorghum bicolor	32.67	1.00e-73	268.00
IUUC-Sre-115058	Sporisorium reilianum	38.33	7.00e-69	253.00
IUUC-Tgu-116772	Taeniopygia guttata	32.43	7.00e-76	276.00
IUUC-Tru-118686	Takifugu rubripes	35.28	1.00e-92	332.00
IUUC-Tsy-119111	Tarsius syrichta	34.59	6.00e-42	163.00
IUUC-Tni-120231	Tetraodon nigroviridis	31.86	1.00e-76	278.00
IUUC-Tca-121491	Theobroma cacao	33.03	8.00e-70	256.00
IUUC-Tre-122103	Trichoderma reesei	46.23	1.00e-135	474.00
IUUC-Tvi-122672	Trichoderma virens	44.86	4.00e-133	466.00
IUUC-Tae-125684	Triticum aestivum	32.80	1.00e-74	272.00
IUUC-Tur-126487	Triticum urartu	31.85	4.00e-70	256.00
IUUC-Tme-127097	Tuber melanosporum	38.65	7.00e-98	349.00
IUUC-Ttr-128465	Tursiops truncatus	31.90	6.00e-73	266.00
IUUC-Uma-129645	Ustilago maydis	38.33	4.00e-70	257.00
IUUC-Vda-129989	Verticillium dahliae	41.62	9.00e-107	378.00
IUUC-Vpa-130529	Vicugna pacos	32.26	1.00e-76	278.00
IUUC-Vvi-131059	Vitis vinifera	32.48	1.00e-73	268.00
IUUC-Xtr-132002	Xenopus tropicalis	36.17	2.00e-93	334.00
IUUC-Xma-133930	Xiphophorus maculatus	35.07	5.00e-89	320.00
IUUC-Yli-134505	Yarrowia lipolytica	33.75	7.00e-81	292.00
IUUC-Zma-135619	Zea mays	31.74	1.00e-70	259.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence