iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-107301

Ensembl Protein ID

ENSSHAP00000008064.1

UniProt Accession

G3VY09; G3VY09_SARHA

Genbank Protein ID

ENSSHAP00000008064

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01160639

Gene Name

COPA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000006995.1	ENSSHAT00000008128.1	ENSSHAP00000008064.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-35	118.4	37	67
UBD/Beta-Prp	1.80e-74	250.7	2	311

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDl 30
           H ++v++++f  + +l+vsG+dD +ikvW++
   Q: 37   HDGPVRGIDFhkQQPLFVSGGDDYKIKVWNY 67
           99********97449**************96 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           + f+p++++++t+  +g i++wd+++ +l+ ++ +h+++v+ ++f+++++++v+g++D+ ikvw+++ + c+ tl gh d+++++ f+ 
   Q: 2    LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHH 90
           579************************************************************************************** PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl........................... 166
           +  +++s+s+d+tirvw++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                           
   Q: 91   EYPWILSASDDQTIRVWNWQSRTCVC-VLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIsglrkknlspgavesdvrgitgvdlfg 178
           **************************.************************************************************** PP
   S: 167  ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrs 253
            t+ ++++  +gh++ v++ +f+++++ +vsg++d++vk+w + +++   v+t++gh +nv++  f+p++e+++s s+D+sir+Wd+ +
   Q: 179  TTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAweVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSK 267
           888888888777********************************888888*************************************** PP
   S: 254  gdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           ++ ++t+ + +++++  a+ +++ n +++g  d+   ++kl++++p
   Q: 268  RTGVQTFRRDHDRFWVLAA-HPNLNLFAAG-HDGGMIVFKLERERP 311
           *******************.5554444444.589999999988765 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

GLSFHPKRPW ILTSLHNGVI QLWDYRMCTL IDKFDEHDGP VRGIDFHKQQ PLFVSGGDDY 60
KIKVWNYKLR RCLFTLLGHL DYIRTTFFHH EYPWILSASD DQTIRVWNWQ SRTCVCVLTG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGACTCAGCT TTCACCCCAA ACGACCCTGG ATCTTGACTA GTCTTCACAA TGGAGTCATC 60
CAGCTCTGGG ATTACCGGAT GTGTACCCTC ATTGACAAAT TTGATGAGCA CGATGGTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030157--P:pancreatic juice secretion
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	53.40	0.00e+00	1310.00
IUUC-Aml-001758	Ailuropoda melanoleuca	97.30	0.00e+00	2449.00
IUUC-Atr-002493	Amborella trichopoda	53.82	0.00e+00	1297.00
IUUC-Apl-003385	Anas platyrhynchos	96.52	0.00e+00	2073.00
IUUC-Aca-005154	Anolis carolinensis	96.91	3.00e-114	403.00
IUUC-Aly-006020	Arabidopsis lyrata	52.98	0.00e+00	1295.00
IUUC-Ath-007058	Arabidopsis thaliana	53.23	0.00e+00	1283.00
IUUC-Ago-007992	Ashbya gossypii	44.37	0.00e+00	1011.00
IUUC-Acl-008027	Aspergillus clavatus	57.02	0.00e+00	988.00
IUUC-Afl-008644	Aspergillus flavus	57.04	0.00e+00	985.00
IUUC-Afu-008964	Aspergillus fumigatus	48.94	0.00e+00	1179.00
IUUC-Ani-009379	Aspergillus nidulans	56.28	0.00e+00	994.00
IUUC-Ang-009756	Aspergillus niger	49.88	0.00e+00	1197.00
IUUC-Aor-010174	Aspergillus oryzae	57.04	0.00e+00	985.00
IUUC-Ate-010302	Aspergillus terreus	49.59	0.00e+00	1214.00
IUUC-Ame-011229	Astyanax mexicanus	86.62	0.00e+00	2180.00
IUUC-Bgr-012300	Blumeria graminis	48.43	0.00e+00	1144.00
IUUC-Bta-012524	Bos taurus	97.77	0.00e+00	2431.00
IUUC-Bci-013781	Botrytis cinerea	48.37	0.00e+00	1178.00
IUUC-Bdi-014549	Brachypodium distachyon	54.05	0.00e+00	1330.00
IUUC-Bol-015925	Brassica oleracea	61.27	0.00e+00	1061.00
IUUC-Bra-016978	Brassica rapa	60.56	0.00e+00	1058.00
IUUC-Cel-018115	Caenorhabditis elegans	64.31	0.00e+00	1108.00
IUUC-Cja-019107	Callithrix jacchus	94.84	0.00e+00	2382.00
IUUC-Cfa-020675	Canis familiaris	97.36	0.00e+00	2433.00
IUUC-Cpo-021813	Cavia porcellus	97.77	0.00e+00	2449.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	64.21	0.00e+00	1091.00
IUUC-Csa-023523	Chlorocebus sabaeus	98.10	0.00e+00	2469.00
IUUC-Cho-024704	Choloepus hoffmanni	83.58	0.00e+00	1883.00
IUUC-Cin-025572	Ciona intestinalis	72.56	0.00e+00	1857.00
IUUC-Csv-025864	Ciona savignyi	75.27	0.00e+00	1278.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	57.04	0.00e+00	1003.00
IUUC-Cne-027053	Cryptococcus neoformans	51.64	0.00e+00	1231.00
IUUC-Cme-027222	Cyanidioschyzon merolae	32.34	8.00e-164	571.00
IUUC-Dre-027421	Danio rerio	86.72	0.00e+00	2215.00
IUUC-Dno-029303	Dasypus novemcinctus	97.70	0.00e+00	2450.00
IUUC-Dor-030290	Dipodomys ordii	96.11	0.00e+00	1102.00
IUUC-Dse-031543	Dothistroma septosporum	46.18	0.00e+00	1108.00
IUUC-Dme-031945	Drosophila melanogaster	76.03	0.00e+00	1277.00
IUUC-Ete-032873	Echinops telfairi	91.73	0.00e+00	2115.00
IUUC-Eca-033773	Equus caballus	95.63	0.00e+00	2380.00
IUUC-Eeu-034874	Erinaceus europaeus	84.32	0.00e+00	1491.00
IUUC-Fca-035739	Felis catus	96.89	0.00e+00	2372.00
IUUC-Fal-037263	Ficedula albicollis	88.09	0.00e+00	2132.00
IUUC-Fox-037738	Fusarium oxysporum	48.05	0.00e+00	1197.00
IUUC-Fso-038153	Fusarium solani	48.77	0.00e+00	1185.00
IUUC-Gmo-039602	Gadus morhua	81.55	0.00e+00	2036.00
IUUC-Ggr-039931	Gaeumannomyces graminis	56.11	0.00e+00	998.00
IUUC-Gga-040590	Gallus gallus	97.11	0.00e+00	2405.00
IUUC-Gac-041318	Gasterosteus aculeatus	86.46	0.00e+00	2198.00
IUUC-Gma-043894	Glycine max	54.66	0.00e+00	1334.00
IUUC-Ggo-045029	Gorilla gorilla	97.21	0.00e+00	2457.00
IUUC-Hsa-046078	Homo sapiens	97.21	0.00e+00	2457.00
IUUC-Hvu-047556	Hordeum vulgare	54.87	0.00e+00	1345.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	96.47	0.00e+00	1721.00
IUUC-Kpa-049256	Komagataella pastoris	44.95	0.00e+00	1074.00
IUUC-Lch-049706	Latimeria chalumnae	92.82	0.00e+00	2299.00
IUUC-Lpe-051316	Leersia perrieri	62.41	0.00e+00	1088.00
IUUC-Loc-051867	Lepisosteus oculatus	71.85	0.00e+00	1199.00
IUUC-Lma-053138	Leptosphaeria maculans	48.05	0.00e+00	1157.00
IUUC-Laf-053510	Loxodonta africana	97.36	0.00e+00	2449.00
IUUC-Mcc-055836	Macaca mulatta	97.05	0.00e+00	2440.00
IUUC-Meu-056238	Macropus eugenii	93.02	0.00e+00	1177.00
IUUC-Mor-057172	Magnaporthe oryzae	48.33	0.00e+00	1180.00
IUUC-Mpo-057300	Magnaporthe poae	48.96	0.00e+00	1166.00
IUUC-Mtr-058248	Medicago truncatula	55.04	0.00e+00	1349.00
IUUC-Mla-059019	Melampsora laricipopulina	52.04	0.00e+00	1272.00
IUUC-Mga-059499	Meleagris gallopavo	96.95	0.00e+00	2400.00
IUUC-Mvi-060336	Microbotryum violaceum	52.70	0.00e+00	1253.00
IUUC-Mmr-061102	Microcebus murinus	97.30	0.00e+00	2413.00
IUUC-Mdo-062594	Monodelphis domestica	99.17	0.00e+00	2514.00
IUUC-Mmu-063736	Mus musculus	96.64	0.00e+00	2433.00
IUUC-Mac-065398	Musa acuminata	51.60	0.00e+00	1221.00
IUUC-Mpu-066701	Mustela putorius furo	97.53	0.00e+00	2410.00
IUUC-Mlu-067392	Myotis lucifugus	97.69	0.00e+00	2422.00
IUUC-Nfi-068270	Neosartorya fischeri	57.26	0.00e+00	991.00
IUUC-Ncr-068892	Neurospora crassa	49.15	0.00e+00	1173.00
IUUC-Nle-069634	Nomascus leucogenys	99.23	0.00e+00	1353.00
IUUC-Opr-070952	Ochotona princeps	84.82	0.00e+00	1783.00
IUUC-Ont-072488	Oreochromis niloticus	88.36	0.00e+00	2212.00
IUUC-Ocu-074211	Oryctolagus cuniculus	98.02	0.00e+00	2456.00
IUUC-Oba-075761	Oryza barthii	62.29	0.00e+00	1088.00
IUUC-Obr-076429	Oryza brachyantha	62.29	0.00e+00	1087.00
IUUC-Ogl-077364	Oryza glaberrima	62.29	0.00e+00	1088.00
IUUC-Ogu-078257	Oryza glumaepatula	62.42	0.00e+00	1086.00
IUUC-Oin-079274	Oryza indica	62.17	0.00e+00	1087.00
IUUC-Olo-080466	Oryza longistaminata	62.19	0.00e+00	1073.00
IUUC-Ome-081668	Oryza meridionalis	62.41	0.00e+00	934.00
IUUC-Oni-082874	Oryza nivara	62.29	0.00e+00	1087.00
IUUC-Opu-083697	Oryza punctata	53.48	0.00e+00	1316.00
IUUC-Oru-084274	Oryza rufipogon	62.29	0.00e+00	1088.00
IUUC-Osa-085565	Oryza sativa	62.29	0.00e+00	1088.00
IUUC-Ola-086921	Oryzias latipes	86.74	0.00e+00	2177.00
IUUC-Olu-087639	Ostreococcus lucimarinus	55.44	0.00e+00	1345.00
IUUC-Oga-087991	Otolemur garnettii	92.51	0.00e+00	2311.00
IUUC-Oar-089590	Ovis aries	97.85	0.00e+00	2459.00
IUUC-Ptr-090808	Pan troglodytes	97.30	0.00e+00	2457.00
IUUC-Pan-092475	Papio anubis	97.77	0.00e+00	2458.00
IUUC-Psi-093044	Pelodiscus sinensis	80.06	0.00e+00	1695.00
IUUC-Pno-094839	Phaeosphaeria nodorum	47.97	0.00e+00	1119.00
IUUC-Ppa-095254	Physcomitrella patens	56.05	0.00e+00	1385.00
IUUC-Pfo-097493	Poecilia formosa	88.03	0.00e+00	2184.00
IUUC-Pab-098497	Pongo abelii	98.10	0.00e+00	2471.00
IUUC-Pop-099992	Populus trichocarpa	56.05	0.00e+00	1328.00
IUUC-Pca-100413	Procavia capensis	89.29	0.00e+00	1011.00
IUUC-Ppe-101899	Prunus persica	54.31	0.00e+00	1314.00
IUUC-Pva-102126	Pteropus vampyrus	93.44	0.00e+00	2337.00
IUUC-Pgr-103376	Puccinia graminis	52.35	0.00e+00	1292.00
IUUC-Ptt-103978	Puccinia triticina	47.92	0.00e+00	1086.00
IUUC-Pte-104126	Pyrenophora teres	55.34	0.00e+00	984.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	45.77	1.00e-180	626.00
IUUC-Rno-105428	Rattus norvegicus	97.36	0.00e+00	2443.00
IUUC-Sce-106464	Saccharomyces cerevisiae	43.47	0.00e+00	994.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	45.53	0.00e+00	1080.00
IUUC-Spo-108217	Schizosaccharomyces pombe	47.08	0.00e+00	1123.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	48.49	0.00e+00	1187.00
IUUC-Smo-109582	Selaginella moellendorffii	65.33	0.00e+00	1135.00
IUUC-Sit-109697	Setaria italica	61.80	0.00e+00	1080.00
IUUC-Sly-111447	Solanum lycopersicum	54.68	0.00e+00	1346.00
IUUC-Stu-112564	Solanum tuberosum	54.46	0.00e+00	1344.00
IUUC-Sar-113313	Sorex araneus	87.56	0.00e+00	1481.00
IUUC-Sbi-114388	Sorghum bicolor	54.14	0.00e+00	1335.00
IUUC-Sre-115209	Sporisorium reilianum	57.42	0.00e+00	1028.00
IUUC-Ssc-115933	Sus scrofa	98.10	0.00e+00	2461.00
IUUC-Tgu-117109	Taeniopygia guttata	81.91	0.00e+00	751.00
IUUC-Tru-117772	Takifugu rubripes	86.70	0.00e+00	2164.00
IUUC-Tsy-119105	Tarsius syrichta	83.28	0.00e+00	2057.00
IUUC-Tni-120556	Tetraodon nigroviridis	72.93	0.00e+00	1680.00
IUUC-Tca-121046	Theobroma cacao	54.84	0.00e+00	1353.00
IUUC-Tre-121951	Trichoderma reesei	56.87	0.00e+00	1001.00
IUUC-Tvi-122359	Trichoderma virens	48.62	0.00e+00	1181.00
IUUC-Tae-125527	Triticum aestivum	53.56	0.00e+00	1314.00
IUUC-Tur-126754	Triticum urartu	61.56	0.00e+00	1080.00
IUUC-Tme-127170	Tuber melanosporum	50.33	0.00e+00	1217.00
IUUC-Tbe-127882	Tupaia belangeri	94.72	0.00e+00	828.00
IUUC-Ttr-128217	Tursiops truncatus	95.16	0.00e+00	2380.00
IUUC-Uma-129337	Ustilago maydis	56.71	0.00e+00	1026.00
IUUC-Vda-129828	Verticillium dahliae	48.13	0.00e+00	1168.00
IUUC-Vpa-130537	Vicugna pacos	96.80	0.00e+00	2411.00
IUUC-Vvi-130958	Vitis vinifera	62.90	0.00e+00	1096.00
IUUC-Xtr-132857	Xenopus tropicalis	89.57	0.00e+00	2261.00
IUUC-Xma-133138	Xiphophorus maculatus	87.86	0.00e+00	2180.00
IUUC-Yli-134399	Yarrowia lipolytica	50.65	0.00e+00	851.00
IUUC-Zma-135612	Zea mays	53.85	0.00e+00	1323.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence