iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.40e-34	117.2	8	138

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdppegisakpvdesd.ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk..ifhPnvyenGkvClsilkeeekWspalsv 98
           Rl+kel++l+++ peg+ ++ ++ s+ l++w++ ++G e+t Y+g+vF l+++f ++YPf++P+v+f+ +    hP++y+nG++Clsil   ++W+palsv
   Q: 8    RLMKELAQLKSEAPEGLLVDNTSTSNdLKQWKIGVVGAEGTLYAGEVFMLQFTFGPQYPFNSPEVMFVGEtiPAHPHIYSNGHICLSILS--DDWTPALSV 106
           9****************9987765544*****************************************997789***************9..********* PP
   S: 99   esvllsiqsll.aepnpesplneeaa.ellkk 128
           +sv+lsi s+l ++ + ++p ++ ++ ++++k
   Q: 107  QSVCLSILSMLsSSKEKKHPIDDAIYvRTCSK 138
           ***********545777888888777344444 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MSDAATRRLM KELAQLKSEA PEGLLVDNTS TSNDLKQWKI GVVGAEGTLY AGEVFMLQFT 60
FGPQYPFNSP EVMFVGETIP AHPHIYSNGH ICLSILSDDW TPALSVQSVC LSILSMLSSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGCCTCCAC TCATCAGGAA TGTCAGATGC TGCGACAAGA CGACTGATGA AAGAGCTGGC 60
TCAACTGAAA AGTGAGGCTC CAGAAGGGCT TTTAGTGGAT AATACATCAA CAAGTAACGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

KEGG

cel:CELE_Y54E5B.4

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000363	Aegilops tauschii	44.16	2.00e-32	130.00
IUUC-Aml-002375	Ailuropoda melanoleuca	60.69	7.00e-49	184.00
IUUC-Apl-003950	Anas platyrhynchos	60.56	6.00e-48	181.00
IUUC-Aly-006450	Arabidopsis lyrata	51.30	2.00e-36	143.00
IUUC-Ath-007702	Arabidopsis thaliana	50.65	2.00e-36	143.00
IUUC-Acl-008034	Aspergillus clavatus	36.18	3.00e-21	93.20
IUUC-Afl-008476	Aspergillus flavus	39.24	6.00e-24	102.00
IUUC-Afu-008827	Aspergillus fumigatus	37.34	7.00e-23	98.60
IUUC-Ani-009244	Aspergillus nidulans	32.64	2.00e-15	73.60
IUUC-Ang-009545	Aspergillus niger	36.18	1.00e-20	90.50
IUUC-Aor-009924	Aspergillus oryzae	38.10	1.00e-20	90.90
IUUC-Ate-010478	Aspergillus terreus	30.17	3.00e-17	80.10
IUUC-Ame-011757	Astyanax mexicanus	60.81	3.00e-50	189.00
IUUC-Bgr-012004	Blumeria graminis	39.22	9.00e-25	104.00
IUUC-Bta-013365	Bos taurus	60.14	5.00e-50	188.00
IUUC-Bci-013609	Botrytis cinerea	36.13	7.00e-23	98.20
IUUC-Bdi-014373	Brachypodium distachyon	52.60	6.00e-37	145.00
IUUC-Bol-016083	Brassica oleracea	50.66	2.00e-35	140.00
IUUC-Bra-017578	Brassica rapa	50.65	4.00e-34	135.00
IUUC-Cja-018997	Callithrix jacchus	60.42	3.00e-48	182.00
IUUC-Cfa-020790	Canis familiaris	61.38	7.00e-50	188.00
IUUC-Cpo-021615	Cavia porcellus	61.27	2.00e-48	182.00
IUUC-Cre-022615	Chlamydomonas reinhardtii	40.51	2.00e-24	103.00
IUUC-Csa-024236	Chlorocebus sabaeus	60.14	5.00e-50	188.00
IUUC-Cho-024448	Choloepus hoffmanni	53.62	6.00e-38	148.00
IUUC-Cin-025579	Ciona intestinalis	54.11	1.00e-42	164.00
IUUC-Cgl-026554	Colletotrichum gloeosporioides	39.10	3.00e-25	106.00
IUUC-Cme-027157	Cyanidioschyzon merolae	49.06	5.00e-34	135.00
IUUC-Dre-028337	Danio rerio	60.00	3.00e-49	185.00
IUUC-Dno-029321	Dasypus novemcinctus	60.14	5.00e-50	188.00
IUUC-Dor-030985	Dipodomys ordii	68.75	2.00e-41	159.00
IUUC-Dse-031193	Dothistroma septosporum	37.74	6.00e-24	101.00
IUUC-Dme-032116	Drosophila melanogaster	64.38	3.00e-51	193.00
IUUC-Ete-032344	Echinops telfairi	61.38	7.00e-50	187.00
IUUC-Eca-033939	Equus caballus	61.27	2.00e-48	182.00
IUUC-Eeu-034593	Erinaceus europaeus	61.38	7.00e-50	187.00
IUUC-Fca-035457	Felis catus	61.27	2.00e-48	182.00
IUUC-Fal-037512	Ficedula albicollis	63.28	7.00e-45	171.00
IUUC-Fox-038001	Fusarium oxysporum	39.61	3.00e-20	89.70
IUUC-Fso-038237	Fusarium solani	41.56	1.00e-20	90.90
IUUC-Gmo-039574	Gadus morhua	60.14	4.00e-50	188.00
IUUC-Ggr-040091	Gaeumannomyces graminis	36.94	2.00e-24	103.00
IUUC-Gga-040125	Gallus gallus	59.46	1.00e-49	187.00
IUUC-Gac-041300	Gasterosteus aculeatus	58.67	2.00e-49	186.00
IUUC-Gma-043703	Glycine max	48.70	3.00e-32	129.00
IUUC-Ggo-044461	Gorilla gorilla	61.38	7.00e-50	187.00
IUUC-Hsa-046710	Homo sapiens	60.14	9.00e-50	187.00
IUUC-Itr-048816	Ictidomys tridecemlineatus	61.38	6.00e-50	188.00
IUUC-Kpa-049405	Komagataella pastoris	41.10	5.00e-26	108.00
IUUC-Lch-050426	Latimeria chalumnae	58.00	1.00e-48	184.00
IUUC-Lpe-051342	Leersia perrieri	52.60	2.00e-37	146.00
IUUC-Loc-052247	Lepisosteus oculatus	61.38	9.00e-50	187.00
IUUC-Lma-053151	Leptosphaeria maculans	40.52	3.00e-24	103.00
IUUC-Laf-053849	Loxodonta africana	61.27	2.00e-48	182.00
IUUC-Mcc-055520	Macaca mulatta	61.38	1.00e-49	187.00
IUUC-Mor-057224	Magnaporthe oryzae	37.25	1.00e-23	100.00
IUUC-Mpo-057368	Magnaporthe poae	36.94	2.00e-24	103.00
IUUC-Mtr-058781	Medicago truncatula	51.30	8.00e-37	144.00
IUUC-Mla-059112	Melampsora laricipopulina	46.91	5.00e-28	115.00
IUUC-Mga-059919	Meleagris gallopavo	60.69	2.00e-49	186.00
IUUC-Mvi-060408	Microbotryum violaceum	42.95	6.00e-31	125.00
IUUC-Mmr-061136	Microcebus murinus	60.00	2.00e-48	183.00
IUUC-Mdo-062768	Monodelphis domestica	59.46	1.00e-49	187.00
IUUC-Mmu-063097	Mus musculus	60.14	2.00e-49	186.00
IUUC-Mac-064973	Musa acuminata	50.67	4.00e-35	139.00
IUUC-Mpu-066887	Mustela putorius furo	60.00	3.00e-48	182.00
IUUC-Mlu-067762	Myotis lucifugus	60.14	1.00e-49	187.00
IUUC-Nfi-068242	Neosartorya fischeri	35.95	4.00e-21	92.80
IUUC-Ncr-068788	Neurospora crassa	37.25	8.00e-24	101.00
IUUC-Nle-070082	Nomascus leucogenys	61.38	7.00e-50	188.00
IUUC-Ont-072026	Oreochromis niloticus	61.38	6.00e-50	188.00
IUUC-Oan-073013	Ornithorhynchus anatinus	62.50	3.00e-44	168.00
IUUC-Ocu-074009	Oryctolagus cuniculus	61.27	2.00e-48	183.00
IUUC-Oba-075133	Oryza barthii	52.60	2.00e-37	146.00
IUUC-Obr-076142	Oryza brachyantha	53.25	2.00e-38	149.00
IUUC-Ogl-077944	Oryza glaberrima	51.95	4.00e-37	145.00
IUUC-Ogu-078744	Oryza glumaepatula	52.60	2.00e-37	146.00
IUUC-Oin-079726	Oryza indica	52.60	2.00e-37	146.00
IUUC-Olo-080356	Oryza longistaminata	51.95	4.00e-37	145.00
IUUC-Ome-081951	Oryza meridionalis	52.60	2.00e-37	146.00
IUUC-Oni-082217	Oryza nivara	52.60	2.00e-37	146.00
IUUC-Opu-083614	Oryza punctata	51.30	8.00e-37	144.00
IUUC-Oru-084326	Oryza rufipogon	52.60	2.00e-37	146.00
IUUC-Osa-085683	Oryza sativa	52.60	2.00e-37	146.00
IUUC-Ola-086845	Oryzias latipes	56.12	6.00e-32	127.00
IUUC-Oga-087990	Otolemur garnettii	61.38	6.00e-50	188.00
IUUC-Oar-090149	Ovis aries	61.27	2.00e-48	183.00
IUUC-Ptr-090701	Pan troglodytes	61.38	9.00e-50	187.00
IUUC-Pan-092007	Papio anubis	61.38	9.00e-50	187.00
IUUC-Psi-093380	Pelodiscus sinensis	60.69	2.00e-49	186.00
IUUC-Pma-094682	Petromyzon marinus	64.83	3.00e-51	192.00
IUUC-Ppa-095456	Physcomitrella patens	51.30	2.00e-32	130.00
IUUC-Pfo-097000	Poecilia formosa	60.14	1.00e-49	187.00
IUUC-Pab-098188	Pongo abelii	60.14	5.00e-50	188.00
IUUC-Pop-099724	Populus trichocarpa	48.00	2.00e-30	123.00
IUUC-Pca-100346	Procavia capensis	61.43	3.00e-47	179.00
IUUC-Ppe-101300	Prunus persica	49.66	5.00e-31	125.00
IUUC-Pva-102207	Pteropus vampyrus	68.75	1.00e-41	159.00
IUUC-Pgr-103668	Puccinia graminis	43.53	1.00e-31	127.00
IUUC-Pte-104294	Pyrenophora teres	42.86	1.00e-21	94.00
IUUC-Pyt-104534	Pyrenophora triticirepentis	42.06	2.00e-20	89.70
IUUC-Rno-105466	Rattus norvegicus	60.81	2.00e-50	189.00
IUUC-Sha-106707	Sarcophilus harrisii	60.56	7.00e-48	181.00
IUUC-Smo-109161	Selaginella moellendorffii	52.63	3.00e-38	149.00
IUUC-Sit-110080	Setaria italica	52.60	1.00e-37	147.00
IUUC-Sly-111778	Solanum lycopersicum	50.65	4.00e-33	132.00
IUUC-Stu-112037	Solanum tuberosum	50.65	2.00e-32	130.00
IUUC-Sar-113531	Sorex araneus	60.96	7.00e-50	187.00
IUUC-Sbi-114650	Sorghum bicolor	52.60	1.00e-37	147.00
IUUC-Sre-114974	Sporisorium reilianum	40.79	7.00e-28	114.00
IUUC-Ssc-115770	Sus scrofa	61.38	5.00e-50	188.00
IUUC-Tgu-117316	Taeniopygia guttata	60.69	2.00e-49	186.00
IUUC-Tru-117640	Takifugu rubripes	60.00	2.00e-48	183.00
IUUC-Tsy-119222	Tarsius syrichta	60.84	1.00e-48	184.00
IUUC-Tni-120737	Tetraodon nigroviridis	59.46	2.00e-49	186.00
IUUC-Tca-121226	Theobroma cacao	50.34	4.00e-31	125.00
IUUC-Tre-121998	Trichoderma reesei	38.96	1.00e-15	74.30
IUUC-Tvi-122565	Trichoderma virens	40.26	1.00e-21	94.40
IUUC-Tae-124081	Triticum aestivum	53.25	1.00e-37	147.00
IUUC-Tur-126577	Triticum urartu	58.06	5.00e-34	135.00
IUUC-Tme-127110	Tuber melanosporum	39.47	2.00e-23	100.00
IUUC-Tbe-127701	Tupaia belangeri	61.38	8.00e-50	187.00
IUUC-Ttr-128279	Tursiops truncatus	56.64	3.00e-43	165.00
IUUC-Uma-129371	Ustilago maydis	42.11	4.00e-28	115.00
IUUC-Vda-129698	Verticillium dahliae	35.95	2.00e-23	100.00
IUUC-Vpa-130053	Vicugna pacos	60.45	1.00e-42	163.00
IUUC-Vvi-131254	Vitis vinifera	50.00	1.00e-32	130.00
IUUC-Xtr-132804	Xenopus tropicalis	43.06	1.00e-32	130.00
IUUC-Xma-133451	Xiphophorus maculatus	60.14	1.00e-49	187.00
IUUC-Yli-134332	Yarrowia lipolytica	48.00	1.00e-31	127.00
IUUC-Zma-135814	Zea mays	52.60	4.00e-38	149.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence